Study on Seismic Response Characteristics of Shield Tunnel in Soil-Rock Combination Stratum by Guang-Biao Shao, Xi-Sen Fan, Jin-Hua Shang, Li-Xin Lu

“…To explore the influence of soil-rock combination stratum vibration on the shield tunnel, the section of Jinan rail transit line 4 at the Olympic Sports Center is used as the research background. …”
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Radio- and Power-Over-Fiber Integration for 6G Networks: Challenges and Future Prospects by Leticia Carneiro de Souza, Victoria Dala Pegorara Souto, Arismar Cerqueira Sodre

“…Furthermore, the main challenges and limitations of RPoF systems are identified, including power transmission efficiency (PTE), optical fiber design and deployment, scalability, capacity, safety, and reliability. Finally, we discuss the potential research directions and technological advancements needed to fully exploit the capabilities of RPoF in the 6G era.…”
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Microplastic and human health with focus on pediatric well-being: a comprehensive review and call for future studies by Rogers Wainkwa Chia, Ntegang Venant Atem, Jin-Yong Lee, Jihye Cha

“…The samples were then treated with Fenton's reagent, stored in glass jars, and filtered through nonplastic filters. Finally, MPs in children were quantified using stereomicroscopy and characterized using micro-Fourier transform infrared spectroscopy.…”
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Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis by Louisane Desbiens, Catherine Lapointe, Marjan Gharagozloo, Shaimaa Mahmoud, Gunnar Pejler, Denis Gris, Pedro D’Orléans-Juste

“…In addition, higher levels of spinal myelin were found in mMCP-4 KO as compared with WT mice. Finally, whereas EAE triggered significant increases in brain levels of mMCP-4 mRNA and immunoreactive ET-1 in WT mice, the latter peptide was reduced to basal levels in mMCP-4 KO congeners. …”
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An Integrated Strategy for Hybrid Energy Storage Systems to Stabilize the Frequency of the Power Grid Through Primary Frequency Regulation by Dan Zhou, Zhiwei Zou, Yangqing Dan, Chenxuan Wang, Chenyuan Teng, Yuanlong Zhu

“…When the system frequency lies within the DB of the HESS, an SOC self-recovery strategy restores the BESS SOC to an ideal range, further enhancing its long-term frequency regulation (FR) capability. Finally, a regional power grid FR model is established in the RT-1000 real-time simulation system. …”
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Comparison and Estimation of Surface Albedo of Various Levels of Land use by SEBAL and METRIC Methods by Mehdi Asadi, Khalil Valizadeh khamran, Mohammad Baaghdeh, Hamed Adab

“…The amount of albedo was also examined in agricultural (0.240 based on SEBAL method and 0.247 based on METRIC method) and forest lands (0.149 based on SEBAL method and 0.225 based on METRIC method). Finally, according to the results of Albedo values based on SEBAL and METRIC methods, it was concluded that due to the difference in net energy received at different levels, it is possible to estimate the level of albedo levels, which is very effective in estimating evapotranspiration by remote sensing methods.…”
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Sustainable bamboo: Technological innovations and patent insights for a greener future by Himalay R. Patel, Rahil Mathakia, Urvashi C. Mangroliya, Viralkumar B. Mandaliya

“…In the environmental sector, large-scale planting techniques and optimized bamboo plantations have enhanced bamboo’s role in erosion control, land rehabilitation and carbon sequestration. Finally, we demonstrate how bamboo is aligned in achieving Sustainable Development Goals 1–17.…”
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RESIDUAL JURISDICTION VERSUS FORUM NECESSITATIS IN EU FAMILY LAW by Marian GOCIU

“…We will then try to identify the reasons why the Council opted for different regulation of the jurisdiction in question in the family law sub-branches of the Regulations, analyse whether the two legal institutions are likely to achieve their purpose and, finally, we will present our arguments for proposing the adoption of a unitary provision on the matter.…”
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Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells by Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S. Alam, Christina M. Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D. Ashwell, Klaus Strebel, Kyung S. Lee

“…Mechanistically, Vpr forms a cooperative ternary complex with an E3 ligase subunit, VprBP, and polo-like kinase 4 (Plk4). Unexpectedly, however, the complex enhances Plk4’s functionality by promoting its relocalization to the procentriole assembly and induces centrosome amplification. …”
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Research on the Energy-Saving Design Path of Rural Farmhouses under the Background of Ecological Livability by Jingyuan Shi, Qiuna Li

“…It aims to improve the indoor and outdoor thermal environment of farmhouses, saving heating energy consumption in winter and air-conditioning energy consumption in summer and effectively benefit users to use renewable energy such as biogas, straw, and solar energy. Finally, explore the adaptability between the design methods of farmhouses and the local characteristics of Chongqing’s rural areas. …”
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Adaptive Frequency Regulation of Doubly-Fed Pumped Storage Unit Considering Speed and Power Limit by LAO Wenjie, SHI Linjun, WU Feng, YANG Dongmei, LI Yang

“…Based on the proposed method, an adaptive frequency regulation strategy is further presented in which frequency regulation parameters adjust with the change of operating conditions of the unit. Finally, a four-machine two-zone system model with doubly-fed pumped storage unit is built, and the simulation results show that the frequency regulation strategy proposed can make the unit achieve a great frequency regulation performance under different operating conditions.…”
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Enhanced Proliferation of Porcine Bone Marrow Mesenchymal Stem Cells Induced by Extracellular Calcium is Associated with the Activation of the Calcium-Sensing Receptor and ERK Sign... by Jingjing Ye, Wei Ai, Fenglin Zhang, Xiaotong Zhu, Gang Shu, Lina Wang, Ping Gao, Qianyun Xi, YongLiang Zhang, Qingyan Jiang, Songbo Wang

“…Moreover, Ca2+o-induced promotion of pBMSCs proliferation, the changes of proliferative genes expression levels, and the activation of ERK1/2 signaling pathway were effectively blocked by U0126, a selective ERK kinase inhibitor. In conclusion, our findings provided evidence that the enhanced pBMSCs proliferation in response to Ca2+o was associated with the activation of CaSR and ERK1/2 signaling pathway, which may be useful for the application of pBMSCs in future clinical studies aimed at tissue regeneration and repair.…”
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Diagnosis and Management of Atypical Chronic Myeloid Leukemia with a t(2;13)(q33;q12) Translocation by John S. Wang, Omar Elghawy, Brett R. Kurpiel, Michael G. Douvas

“…After clinical progression, he was treated with sorafenib, a multiprotein kinase inhibitor more commonly used in the treatment of hepatocellular and renal cell carcinoma due to its off target FLT3 inhibition. …”
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An Improved Hierarchical Optimization Framework for Walking Control of Underactuated Humanoid Robots Using Model Predictive Control and Whole Body Planner and Controller by Yuanji Liu, Haiming Mou, Hao Jiang, Qingdu Li, Jianwei Zhang

“…Meanwhile, a whole body control (WBC) strategy refines ground reaction forces and joint trajectories under full-body dynamics and contact wrench cone (CWC) constraints, guaranteeing physically realizable interactions with the environment. Finally, a position–velocity–torque (PVT) controller integrates feedforward torque commands with the desired trajectories for robust execution. …”
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Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

“…Abstract Cyclin dependent kinase 2 (CDK2) regulates cell cycle and is an emerging target for cancer therapy. …”
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Study on the Characteristics of Self-Stabilizing Height Distribution for Deep Foundation Pit Vertical Sidewall in Binary Strata of Upper Soil and Lower Rock by Zhang Ziguang, Yihang Li, Jiesheng Zhang, Tao Xu, Guangyong Cao, YiKang Xu

“…The spatial distribution map of the self-stabilizing height for deep foundation pit vertical sidewall in upper soil and lower rock binary stratum has been constructed, and the mathematical fitting equation between Hr0 and Hs has been obtained. Finally, combined with the implementation effect of the deep foundation pit project of Ningxia Road Station for Qingdao Metro Line 3, the rationality of the conclusions is verified. …”
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Radio frequency energy harvesting-combined collaborative energy-saving computation offloading mechanism by Bei TANG, Qian WANG, Siguang CHEN

“…In order to fit the differentiated energy demands in vertical markets and ensure that internet of things (IoT) devices can hold an efficient and sustainable operation mode, a radio frequency energy harvesting-combined collaborative energy-saving computation offloading mechanism was studied.Specifically, a system energy consumption minimization problem was formulated under the joint optimization consideration of computation offloading decision, uplink bandwidth resource allocation, downlink bandwidth resource allocation and base station power splitting.Meanwhile, by combining the concept of penalty function, a new evaluation index was introduced, and then an adaptive particle swarm optimization-based collaborative energy saving computation offloading (APSO-CESCO) algorithm was proposed to solve the problem.The proposed algorithm constructed dynamic inertia weight and linearly adjusted penalty factor, which could alternate the spatial distribution density of the particle community in real-time during the iterative search process, and the optimal computation offloading policy with tolerable punishment could be well-generated.Furthermore, to prevent particles from exceeding exploration range, the velocity boundary was introduced which could also reduce the generation probability of invalid solutions and improve the actual exploration effectiveness.Finally, the simulation results show that the proposed algorithm can achieve higher convergence efficiency and solution accuracy, and compared with other common benchmark schemes, the system energy consumption can be reduced by 34.09%, 14.72%, and 6.86%, respectively.…”
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Using computer modeling to find new LRRK2 inhibitors for parkinson’s disease by María C. García, Sebastián A. Cuesta, José R. Mora, Jose L. Paz, Yovani Marrero-Ponce, Frank Alexis, Edgar A. Márquez

“…The dataset was constructed using pIC50 values of various compounds targeting the inhibition of leucine-rich repeat kinase 2 (LRRK2). The best ensemble model showed exceptional predictive performance, with five-fold cross-validation and external validation metrics exceeding 0.8 (Q2cv = 0.864 and Q2ext = 0.873). …”
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Precision medicine using molecular-target drugs in psoriatic arthritis by Ippei Miyagawa, Yoshiya Tanaka

“…As the pathology of PsA has been clarified, molecular-targeted drugs targeting tumor necrosis factor-α, interleukin (IL)-17A, IL-17A/F, IL-17 receptor, IL-12/23(p40), IL-23p19, Cytotoxic T-lymphocyte Antigen-4 (CTLA-4), Janus kinase, and phosphodiesterase-4 have been developed and are widely used in clinical practice. …”
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Incoherent Integration Detection Method of Airborne Phased Array Radar in a Multipath Environment by Yili Hu, Yongbo Zhao, Sheng Chen

“…In essence, the proposed method makes full use of multipath energy to improve the detection capability of airborne PAR in the multipath environment. Finally, the detection probability of the proposed method is given, and the detection performance is analyzed.…”
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