ATP-Binding Pocket-Targeted Suppression of Src and Syk by Luteolin Contributes to Its Anti-Inflammatory Action by Jeong-Oog Lee, Deok Jeong, Mi-Yeon Kim, Jae Youl Cho

“…Luteolin displayed potent NO-inhibitory activity and also suppressed the nuclear translocation of NF-κB (p65 and p50) via blockade of Src and Syk, but not other mitogen-activated kinases. Overexpression of wild type Src and point mutants thereof, and molecular modelling studies, suggest that the ATP-binding pocket may be the luteolin-binding site in Src. …”
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Vibration Images-Driven Fault Diagnosis Based on CNN and Transfer Learning of Rolling Bearing under Strong Noise by Hongwei Fan, Ceyi Xue, Xuhui Zhang, Xiangang Cao, Shuoqi Gao, Sijie Shao

“…Each kind of sample research compares the impact of thirteen data sharing schemes on the TL accuracy and efficiency, and finally, the test accuracy and time index are introduced to evaluate the model. …”
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Volga Bulgaria and the Near East (Egypt and Syria) in the 10th – early 13th century (based on archaeological materials) by K.A. Rudenko

“…By the beginning of the 13th century the contacts of the Bulgars with the Middle Eastern region were practically interrupted, and were finally lost after the Mongol invasion. And only in the second half – the end of the 13th century, under the rule of the Golden Horde, artistic products of Syrian-Egyptian production are beginning to enter the markets of the Middle Volga region.…”
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Ultrasound-Guided Analgesia in Cardiac and Breast Surgeries: A Cadaveric Comparison of SPIP Block with Single and Double Injections vs. DPIP Block by Carmelo Pirri, Debora Emanuela Torre, Astrid Ursula Behr, Veronica Macchi, Andrea Porzionato, Raffaele De Caro, Carla Stecco

“…Adequate volume facilitates proper spread and diffusion across the fascial plane, ensuring more comprehensive fascia coverage and thus enhancing the block’s effectiveness. Finally, precise volume management is key to maximizing both efficacy and safety.…”
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Six events that shaped antibody approvals in oncology by Suman Paul, Suman Paul, Shibin Zhou, Shibin Zhou

“…We detail the generation of the ADC and BsAb formats that dramatically augmented antibody-mediated precision cytotoxicity. Finally, we explore the development of ipilimumab, the first immune checkpoint-inhibiting antibody that activates the immune system to kill cancer cells, and the discovery that allowed the use of checkpoint inhibitors across all cancer types based on the presence of genetic markers. …”
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Research progress of laser powder bed fusion of Ti2AlNb-based alloys: Microstructure, defects and properties by Jianfa Liao, Aoqi Fan, Haojie Luo, Yulei Du

“…We also summarize effective methods for enhancing mechanical properties. Finally, we propose future development directions, including the design of new alloy compositions, crack control, optimization of heat treatment processes, and performance evaluation of practical engineering components.…”
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Construction of Value Chain E-Commerce Model Based on Stationary Wavelet Domain Deep Residual Convolutional Neural Network by Chenyuan Wang

“…The original loss function based on the residual learning model deep learning is modified to solve the original model fuzzy problem, which improves the effect and has good robustness. Finally, based on the wavelet residual depth residual evaluation method, this paper evaluates the application effect of this model and proposes relevant suggestions for improving this model, including rationalizing and perfecting the external value chain coordination mechanism, establishing the e-commerce value chain sharing center, and promoting integration of e-commerce business, strengthening measures and recommendations in various aspects of e-commerce information construction. …”
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AI-based approaches for improving autonomous mobile robot localization in indoor environments: A comprehensive review by Shoude Wang, Nur Syazreen Ahmad

“…By clarifying these methodologies, our goal is to enhance their comprehension and promote their widespread adoption within the field. Finally, we discuss emerging research directions and ongoing challenges, providing guidance for future investigations and advancements in the domain of indoor AMR.…”
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Evaluation Method of Roof Damage Degree and a Case Study in Maoping Lead-Zinc Mine, Yunnan by Jun Yang, Linke Qiao, Zhixiu Wang, Han Wang

“…The damage of the top plate is divided into five grades: minor damage, obvious damage, serious damage, extremely serious damage, and devastating damage. Finally, the established evaluation method was applied to the project site-supporting work of the 760 m main transport roadway in Yunnan Maoping Lead-Zinc Mine. …”
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The Complexity of Social Networks in Healthy Aging: Novel Metrics and Their Associations with Psychological Well-Being by Sueur, Cédric, Fancello, Giovanna, Naud, Alexandre, Kestens, Yan, Chaix, Basile

“…Dimension 4 was linked with perceived accessibility to local services. Finally, and rather surprisingly, we found that none of the four network dimensions, even the degree, were linked to the three health status metrics.…”
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Dual-Band Integrated Antennas for DVB-T Receivers by Andrea D'alessandro, Roberto Caso, Marcos R. Pino, Paolo Nepa

“…They are composed of a series of branches, properly dimensioned and separated to generate the required resonances. Finally, to show the extreme flexibility of the previous two configurations, a novel dual-band L-shape PIFA has been designed. …”
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Effective Connectivity Study Guiding the Neuromodulation Intervention in Figurative Language Comprehension Using Optical Neuroimaging by Tania Alexandra Couto, Shiyang Xu, Paulo Armada da Silva, Chenggang Wu, Karl Neergaard, Meng-Yun Wang, Juan Zhang, Yutao Xiang, Zhen Yuan

“…Moreover, the interhemispheric directional flow suggests a right hemisphere engagement in decoding unfamiliar literal sentences and fine-grained integration guided by the left hemisphere to reduce ambiguity in meaningless words. Finally, bottom-up mechanisms seem activated by logographic-semantic processing in literal meanings and memory storage centres in meaningless comprehension. …”
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Applying cognitive diagnostic models to mechanics concept inventories by Vy Le, Jayson M. Nissen, Xiuxiu Tang, Yuxiao Zhang, Amirreza Mehrabi, Jason W. Morphew, Hua Hua Chang, Ben Van Dusen

“…Second, we coded the items on RBAs using the student models. Finally, we then tested and refined this coding using a common cognitive diagnostic model, the deterministic inputs, noisy “and” gate model. …”
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Immune Dysfunction in Rett Syndrome Patients Revealed by High Levels of Serum Anti-N(Glc) IgM Antibody Fraction by Anna Maria Papini, Francesca Nuti, Feliciana Real-Fernandez, Giada Rossi, Caterina Tiberi, Giuseppina Sabatino, Shashank Pandey, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Roberto Guerranti, Solange Lavielle, Lucia Ciccoli, Paolo Rovero, Claudio De Felice, Joussef Hayek

“…Rett syndrome (RTT), a neurodevelopmental disorder affecting exclusively (99%) female infants, is associated with loss-of-function mutations in the gene encoding methyl-CpG binding protein 2 (MECP2) and, more rarely, cyclin-dependent kinase-like 5 (CDKL5) and forkhead box protein G1 (FOXG1). …”
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Hierarchical Optimization Segmentation and Parameter Extraction of Street Trees Based on Topology Checking and Boundary Analysis from LiDAR Point Clouds by Yuan Kou, Xianjun Gao, Yue Zhang, Tianqing Liu, Guanxing An, Fen Ye, Yongyu Tian, Yuhan Chen

“…Then, the over-segmentation and under-segmentation situations that occur during the segmentation process are processed and optimized through projection topology checking and tree adaptive voxel bound analysis. Finally, the overall high-precision segmentation of roadside trees is completed, and relevant parameters such as tree height, diameter at breast height, and crown area are extracted. …”
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Osthole regulates N6‐methyladenosine‐modified TGM2 to inhibit the progression of rheumatoid arthritis and associated interstitial lung disease by Xian Lin, Jian Chen, Cheng Tao, Lianxiang Luo, Juan He, Qingwen Wang

“…Furthermore, OS restrained the proliferation and polarization of M2 macrophages to inhibit the aggregation of lung interstitial CD11b+ macrophages, and the effectiveness and non‐toxicity of OS in suppressing RA and RA‐ILD progression were verified in vivo. Finally, bioinformatics analyses validated the importance and the clinical significance of the OS‐regulated molecular network. …”
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Urban Planning Image Feature Enhancement and Simulation Based on Partial Differential Equation Method by Duo Li

“…The difference image is obtained by the domain difference method, and finally, the difference image is classified by the clustering algorithm, and the change area is extracted. …”
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Nurse-led counselling programme on the adherence to eye patch application among children with amblyopia: a randomised control trial by Srishti Raj, Savleen Kaur, Mona Duggal, Shivani ­, Sushma Kumari Saini

“…Standard care was given to the children of the control group. Both groups were finally evaluated at third month on adherence to eye patch application and visual acuity.Result The adherence to eye patch application, vision (as per logMAR chart) knowledge and practices of eye patch application was significantly better in the experimental group as compared with the control group (p<0.01).Conclusion The nurse-led counselling programme demonstrated improvement in visual outcomes and adherence to eye patch application.…”
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Stimuli-responsive hydrogel dressing for wound healing by Wei Zhang, Jun Hu, Hao Wu, Xiufei Lin, Limei Cai

“…Furthermore, we explore several promising tissue-engineered constructs (nanofibers, scaffolds, microneedles, and microspheres). Finally, summarize stimulus-responsive wound dressings on the basis of active research challenges, current research progress, and development trends in the field.…”
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Inhibition of Src signaling induces autophagic killing of Toxoplasma gondii via PTEN-mediated deactivation of Akt. by Alyssa Hubal, Anusha Vendhoti, Charles N Shaffer, Sarah Vos, Yalitza Lopez Corcino, Carlos S Subauste

“…Src knockdown or treatment with the Src family kinase inhibitor, Saracatinib, impaired these events, leading to PTEN accumulation around the PV and a reduction in activated Akt recruitment at this site. …”
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