PGE2 Desensitizes β-Agonist Effect on Human Lung Fibroblast-Mediated Collagen Gel Contraction through Upregulating PDE4 by Qiuhong Fang, Yingmin Ma, Jing Wang, Joel Michalski, Stephen I. Rennard, Xiangde Liu

“…Pretreatment with PGE2 abolished the inhibitory effect of salmeterol, but it potentiated the inhibitory effect of cilomilast on fibroblast-mediated collagen gel contraction. Finally, indomethacin slightly inhibited PDE4C expression, while PGE2 stimulated the expression of PDE4A and -4C in human lung fibroblasts. …”
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Single-Machine Scheduling Problems with the General Sum-of-Processing-Time and Position-Dependent Effect Function by Kunping Shen, Yuke Chen, Shangchia Liu

“…For the sum of the total completion time problem and a1 is the deteriorating rate of the jobs, there exists an optimal solution for a1≥M; a V-shaped property with respect to the normal processing times is obtained for 0<a1≤1. Finally, we show that the sum of the weighted completion problem and the maximum lateness problem have polynomial-time solutions for a1>M under some agreeable conditions, respectively.…”
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Research of the Laser Cladding and Wear-resistance of Worn Surface of Heavy Load Gear of Mining Machine by Zhao Ning, Tao Li, Guo Hui, Zhang Mengqi

“…The slag and rust as well as fatigue spotting layer are completely removed from failure gear flank followed by laser incremental manufacturing and then the SEM analysis of the cross-section of laser cladding layer,wear resistance test is carried out. Finally a conclusion can be drawn,the re-manufacturing tooth surface produced by rectangular spot laser cladding has excellent wear resistance property,there is a high quality metallurgical bonding formed between laser cladding layer and the substrate gear,thus the work surface of gear has reached and surpassed the new product and properly matched the green re-manufacturing standard.…”
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Privacy computing:concept, connotation and its research trend by Feng-hua LI, Hui LI, Yan JIA, Neng-hai YU, Jian WENG

“…Then the privacy computing research category will be discussed from the whole life cycle of information privacy protection. Finally, some research directions of privacy computing are given, including privacy computing model, context adaptive cryptology for privacy protection, big data a lytics resisted privacy control and protection, privacy protection based on information hiding and system architecture for high concurrent privacy preserving services.…”
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Understanding and Perception of Women Career Towards The Principles of Ubudiyyah, Mas'uliyyah and Itqan by Noor Fatimah Mujahid, Nur Aina Mardhiah Che Rahim, Amrina Rasyada Kamaruzaman

“…In addition, this principle tells working women that working is an act of worship to Allah SWT and allows them to devote their time to their household affairs. Finally, the UMI principle is a clear reference and guide for most working women. …”
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Morphological and molecular identification of Particolored bat (Vespertilio murinus) in South Korea: A first record by Bong Kyun Kim, Jeong Hun Shim, Sun Sook Kim, Soo Hyung Eo

“…Additionally, the results of mtDNA sequence analysis indicated that the rescued bat could be differentiated from the closely-related species V. sinensis with respect to the sequences of 13PCGs, COI, Cytb and ND1. Finally, phylogenetic analysis revealed that this bat clustered in a clade with previously described V. murinus. …”
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An Investigation of the Anticancer Mechanism of <i>Caesalpinia sappan</i> L. Extract Against Colorectal Cancer by Integrating a Network Pharmacological Analysis and Experimental Va... by Mibae Jeong, Jaemoo Chun, Sang-Min Park, Heerim Yeo, Se Won Na, In Jin Ha, Bonglee Kim, Mi-Kyung Jeong

“…Western blot analyses confirmed the modulation of critical signaling pathways, including STAT3, AKT, and mitogen-activated protein kinases. Furthermore, CSE significantly suppressed tumor growth in MC38 CRC-bearing mice. …”
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A core-shell magnetic layered double hydroxide composite material for the effective decolorization of phenol red by Şakir Yılmaz

“…The optimal conditions for the PR decolorization efficiency were determined as 5.38, 24.59 mg, and 25.39 mg/L for pH, adsorbent dosage, and Co, respectively which resulted in 86.93% the PR decolorization efficiency. Finally, this work demonstrated that BBD could easefully be utilized for the optimization of the PR decolorization using Fe3O4/NiMn-LDH.…”
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Sherlock-Genome: an R Shiny application for genomic analysis and visualization by Alyssa Klein, Jun Zhong, Maria Teresa Landi, Tongwu Zhang

“…Following FAIR principles, Sherlock-Genome provides a platform and guidelines for managing and sharing finalized sample-level WGS analysis results, enabling users to upload results, inspect analyses locally, and perform integrative analyses. …”
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Dynamics of phase separation from holography by Maximilian Attems, Yago Bea, Jorge Casalderrey-Solana, David Mateos, Miguel Zilhão

“…We numerically solve Einstein’s equations to follow the evolution, in which we identify four generic stages: a first, linear stage in which the instability grows exponentially; a second, non-linear stage in which peaks and/or phase domains are formed; a third stage in which these structures merge; and a fourth stage in which the system finally relaxes to a static, phase-separated configuration. …”
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A szakértői elfogultság a büntetőügyekben II. rész by Márton Lontai, Horolma Pamzsav, Dávid Petrétei

“…Érték: A tanulmány átfogó képet nyújt Itiel Dror munkásságán keresztül a szakértői elfogultság problémájáról, továbbá használható megoldási javaslatokat kínál. …”
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Cytokine-armed oncolytic herpes simplex viruses: a game-changer in cancer immunotherapy? by Howard L Kaufman, Hongbin Wang, Dipongkor Saha, Samuel D Rabkin, Mia Borlongan, Uyen Le, Hans J Nauwynck

“…In this review, we highlight preliminary data with several cytokines and chemokines, including GM-CSF, interleukin 12, FMS-like tyrosine kinase 3 ligand, tumor necrosis factor α, interleukin 2, interleukin 15, interleukin 18, chemokine (C-C motif) ligand 2, chemokine (C-C motif) ligand 5, chemokine (C-X-C motif) ligand 4, or their combinations, and show how these payloads can further enhance the antitumor immunity of oHSV. …”
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All-Consuming Passions: Fire Metaphors in Fiction by Jonathan CHARTERIS-BLACK

“…I also discuss the question of how far empathy and sensual arousal on the part of a reader of romantic fiction may be triggered in the brain by descriptive accounts of people engaging in romantic, affective and, or, sexual activities. Finally I offer two new metaphors specifically for seduction: SEDUCTION IS PLAYING A GAME and SEDUCTION IS FISHING and I suggest possible psychological reasons for their appeal to authors and readers of fiction.…”
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Optimization of Hydraulic Machinery Bladings by Multilevel CFD Techniques by Susanne Thum, Rudolf Schilling

“…After having got a convergent solution, the optimization process is repeated on the second level using a full 3D Euler code yielding a more accurate flow prediction. Finally, a 3D Navier-Stokes code is applied on the third level to search for the optimum optimorum by means of a fine-tuning of the geometrical parameters. …”
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Cómo crear ediciones digitales académicas entre La Habana y Berlín. El caso de Proyecto Humboldt Digital (ProHD) by Antonio Rojas-Castro, Grisel Terrón Quintero, Alaina Solernou Ferrer, Tobias Kraft

“…Also, we describe the model of data representation in TEI format, as well as the tools employed to encode and publish the editions. Finally, we analyze the first editorial results obtained and offer some conclusions on the main challenges faced.…”
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Robust multi-source geographic entities matching by maximizing geometric and semantic similarity by YuHan Yan, PengDa Wu, Yong Yin, PeiPei Guo

“…First, the entire entity is segmented based on shape features, and the partitioned feature segments are extracted as matching primitives; Second, feature segments are grouped into patterns, encompassing three major categories and fourteen subcategories; Following this, pattern matching is performed based on spatial similarity metric such as maximum projection distance, etc.; Finally, the spatial matches are detected and refined through semantic similarity calculation. …”
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Payload State Prediction Based on Real-Time IoT Network Traffic Using Hierarchical Clustering with Iterative Optimization by Hao Zhang, Jing Wang, Xuanyuan Wang, Kai Lu, Hao Zhang, Tong Xu, Yan Zhou

“…Secondly, the classification of payload state within network flows is obtained via a payload extraction module. Finally, the predictor of payload state in a network is trained on a payload set, and these payloads have state labels. …”
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Drug-induced bone disorders: A systematic review by Anshita Aggarwal, Meha Sharma, Indira Maisnam, Soumitra Ghosh, Sameer Aggarwal, Saptarshi Bhattacharya, Deep Dutta

“…Anti-epileptics, proton pump inhibitors, glucocorticoids, immunosuppressants (calcineurin inhibitors), anticoagulants, glitazones, SGLT2 inhibitors, somatostatin analogs, anticancer medications, and protein kinase inhibitors are some of the commonly used medications associated with bone mineral loss. …”
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Goal and shot prediction in ball possessions in FIFA Women’s World Cup 2023: a machine learning approach by Iyán Iván-Baragaño, Antonio Ardá, José L. Losada, Rubén Maneiro

“…The predictive capacity was tested using Random Forest and XGBoost and finally and SHAP values were calculated and visualized to understand the influence of the predictors.ResultsRandom Forest technique showed greater efficacy, with recall and sensitivity above 93% in the resampled dataset. …”
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An Improved Sequential Recommendation Algorithm based on Short-Sequence Enhancement and Temporal Self-Attention Mechanism by Jianjun Ni, Guangyi Tang, Tong Shen, Yu Cai, Weidong Cao

“…Then, the reverse prediction model is used to generate a batch of pseudo-historical items before the initial items of the short sequence, to achieve the goal of enhancing the short sequence. Finally, the absolute position information and time interval information of the user sequence are modeled, and a time-aware self-attention model is adopted to predict the user’s next action and generate a recommendation list. …”
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