Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates by Jennifer N. Wells, Lucy V. Edwardes, Vera Leber, Shenaz Allyjaun, Matthew Peach, Joshua Tomkins, Antonia Kefala-Stavridi, Sarah V. Faull, Ricardo Aramayo, Carolina M. Pestana, Lepakshi Ranjha, Christian Speck

“…We determined the hOCCM structure, which showed that hORC-hCDC6 recruits hMCM2-7 via five hMCM winged-helix domains. The structure highlights how hORC1 activates the hCDC6 ATPase and uncovered an unexpected role for hCDC6 ATPase in complex disassembly. …”
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Investigation into Macro- and Microcrack Propagation Mechanism of Red Sandstone under Different Confining Pressures Using 3D Numerical Simulation and CT Verification by Wen Zhang, Yan-yu Chen, Jin-ping Guo, Sai-sai Wu, Cheng-yuan Yan

“…The accumulated microcracks finally converged to form a macroscopic oblique shear failure. …”
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Load Balancing Selection Method and Simulation in Network Communication Based on AHP-DS Heterogeneous Network Selection Algorithm by Weiwei Xiao

“…Firstly, the training data is obtained from the collaborative algorithm, and it is used as the training set, and the network attributes are used as the attribute set, and the continuous attributes are discretized by dichotomization, and the attribute that can make the greatest information gain is selected as the division feature, and a decision tree with strong generalization ability is finally obtained, which is used as the decision basis for network access selection. …”
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Clinical Features and Risk Factors of Active Tuberculosis in Patients with Behçet’s Disease by Yaxu Liu, Lifan Zhang, Ziyue Zhou, Luxi Sun, Baotong Zhou, Xiaoqing Liu, Wenjie Zheng

“…The control group was selected by random number sampling from the remaining BD patients, including those with latent tuberculosis infection, previous tuberculosis, or without tuberculosis. Finally, we reviewed 386 BD patients and identified 21 (5.4%) ATB cases, including four (19.0%) microbiologically confirmed and 17 (81.0%) clinically diagnosed. …”
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HVSR Analysis of Rockslide Seismic Signals to Assess the Subsoil Conditions and the Site Seismic Response by Alessia Lotti, Veronica Pazzi, Gilberto Saccorotti, Andrea Fiaschi, Luca Matassoni, Giovanni Gigli

“…This can be related to the indirect effect of temperature on rock mass conditions and further extensive studies (also in the time frequency domain) are required to better comprehend this dependency. Finally, the continuous on-line data reveal interesting applications to provide near-real time warning systems for emerging potentially disastrous rockslides.…”
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Solutions of Cauchy Problems for the Caudrey–Dodd–Gibbon–Kotera–Sawada Equation in Three Spatial and Two Temporal Dimensions by Yufeng Zhang, Linlin Gui

“…Then, by transforming two temporal variables, the CDGKS equation in three dimensions is reduced, and the Lax pairs of the corresponding equations are given. Finally, the solutions of Cauchy problems for the CDGKS equation in three spatial and two temporal dimensions are constructed by introducing a novel nonlocal <i>d</i>-bar formalism, in which several new long derivative operators, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>D</mi><mi>x</mi></msub></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>D</mi><mi>y</mi></msub></semantics></math></inline-formula>, and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>D</mi><mi>t</mi></msub></semantics></math></inline-formula>, are constructed for the study of the initial value problem for the CDGKS equation. …”
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Evaluation of Proteins Released to Medium in Yeast-Bacteria Co-culture System by Çağatay Tarhan, Ayşegül Yanık

“…In this study, the wild strain of Schizosaccharomyces pombe and the DH5α strain of Escherichia coli were grown in their own specific media, then cultured for 48 hours and 72 hours by cultivating in media containing 0,1% glucose with different cell number, and finally the differentiation in the proteins released by the cells into the medium was observed in SDS polyacrylamide gels. …”
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Characteristics of patients with somatoform pain disorder by Lena Barth, Linda Baumbach, André Hajek, Lutz Götzmann, Katrin Feiks, Michael Rufer, Kyrill Schwegler, Bianca Schwennen, Kirstin Bernhardt, Uwe Wutzler, Paul Kaiser, Lutz Wittmann, Adrian Siegel

“…Furthermore, patients indicate feelings of helplessness, by agreeing to the expressions the pain controls me (70%). Finally, we found that pain is predominantly seen as suffering, failing to convey emotional pain, despite cognitively acknowledging the dependency of emotional and physical pain. …”
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The 2024 local elections in the Republic of Serbia: Political dynamics and consequences by Matić Petar M., Mijatović Marko R.

“…Forming a particular whole with the local elections held in the city of Belgrade and another 65 municipalities, cities, and urban municipalities in central Serbia, on December 17, 2023, they showed a picture of the political scene of Serbia, its dynamics, actors at the national and local level, their strategies political struggles and, finally, electoral preferences citizens related to the political game in local political arenas. …”
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Evolution of sample-based music authorship network by Dongju Park, Juyong Park

“…The selection, manipulation, and adoption of samples heavily impact the genre, mood, texture, and finally the distinctive identity of a new musical composition. …”
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Biodiesel and Biolubricant Production from Waste Cooking Oil: Transesterification Reactor Modeling by Pedro M. Álvarez, Javier Collado Contreras, Sergio Nogales-Delgado

“…Also, a kinetic study was carried out (at temperatures ranging from 80 to 140 °C and with catalyst concentrations from 0.3 to 0.9% <i>w</i>/<i>w</i> and working pressures from 210 to 760 mmHg) to establish the main kinetic parameters, obtaining a second-order reaction and an activation energy of 17.8 kJ·mol⁻¹. Finally, a conceptual design was included, considering the main components of the facility. …”
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Cross-Linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines by Edismauro Garcia Freitas Filho, Elaine Zayas Marcelino da Silva, Camila Ziliotto Zanotto, Constance Oliver, Maria Célia Jamur

“…The effect of cross-linking the gangliosides on the MAP kinase pathway was then investigated. Cross-linking the gangliosides induced the phosphorylation of ERK1/2, JNK1/2, and p38 as well as activating both NFκB and NFAT in a Syk-dependent manner. …”
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Modulation Signal Bispectrum Slice Overall Average Feature Extraction of Low-speed Reciprocating Bearing Faults by Zhang Hao, Hu Lei, Xu Yuandong, Hu Niaoqing

“…Yaw bearings and slewing bearings in wind turbine systems, rotating support bearings in aerospace launch towers, and slew bearings in cranes and excavators all exhibit characteristics of low-speed reciprocating motion. …”
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Inflammatory Response Mechanisms Exacerbating Hypoxemia in Coexistent Pulmonary Fibrosis and Sleep Apnea by Ayodeji Adegunsoye, Jay Balachandran

“…Adipocytes may induce hypoxia inducible factor (HIF) 1α production; GERD is associated with increased levels of lactate dehydrogenase (LDH), alkaline phosphatase (ALP), and tumor necrosis factor alpha (TNF-α); pulmonary artery myocytes often exhibit increased cytosolic free Ca2+. Protein kinase C (PKC) mediated upregulation of TNF-α and IL-1β also occurs in the pulmonary arteries. …”
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Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

“…Abstract Technical limitations have prevented understanding of how growth factor signals are encoded in distinct activity patterns of the phosphoinositide 3-kinase (PI3K)/AKT pathway, and how this is altered by oncogenic pathway mutations. …”
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Short-hair black holes and the strong cosmic censorship conjecture by Zhiqin Tu, Meirong Tang, Zhaoyi Xu

“…These results suggest that the proximity of the black hole’s charge $$ Q $$ Q to its extremal value, along with the size of the angular quantum number $$ \ell $$ ℓ and the order $$ k $$ k , play key roles in exploring the physical properties of black holes and verifying SCCC. Finally, research using the WGC shows that when the charge-to-mass ratio in a scalar field meets certain conditions, short-hair black holes can still comply with the SCCC under extreme conditions. …”
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Automatic Recommendation Algorithm for Video Background Music Based on Deep Learning by Hong Kai

“…By comprehensively considering user’s interest and video background music characteristics, the collaborative filtering process is supervised, and the optimized prediction result is finally obtained. The performance test and function test of the system were carried out, respectively, to verify the effectiveness of the hybrid recommendation algorithm and the effect of the system for recommendation. …”
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Physical Simulation of the Water-Conducting Fracture Zone of Weak Roofs in Shallow Seam Mining Based on a Self-Designed Hydromechanical Coupling Experiment System by Hao Zha, Weiqun Liu, Qinghong Liu

“…The experimental results show that the vertical stress in the roof increases first as the working face approaches and finally decreases to near its initial value as the working face passes. …”
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Keratin/chitosan film promotes wound healing in rats with combined radiation-wound injury by Yu-mei Wang, Tong Xin, Hao Deng, Jie Chen, Shen-lin Tang, Li-sheng Liu, Xiao-liang Chen

“…A rat model of combined radiation-wound injury was employed to evaluate the therapeutic efficacy of the KRT/CS film. Finally, the systemic biotoxicity of KRT/CS film was assessed through histological analysis. …”
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Identification, evaluation and prioritization of hazards caused by high voltage power towers in urban areas by Negar Afzali Behbahani

“…Also, considering that one of the most important problems in the vicinity of residential areas with high voltage power transmission lines is the effects of magnetic field beams created around it, in order to determine the intensity of the magnetic field, 3D EMF TESTER device was used. Finally, the identified risks were scored based on the parameters of the research method and RPN was calculated for each. …”
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