Transfusion in trauma: empiric or guided therapy? by Liam Barrett, Nicola Curry

“…Greater mechanistic understanding of the underlying pathobiology of trauma-induced coagulopathy and the direct effects of common treatments on this process will be of equal importance to the development of new treatments. Finally, we summarize relevant new data on this topic presented at the 2024 ISTH Congress.…”
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Analysis of Marketing Prediction Model Based on Genetic Neural Network: Taking Clothing Marketing as an Example by Hua Peng, Luxiao Dong, Yi Sun, Yanfang Jiang

“…In the process of estimating and calculating the parameters of the prediction model, an error criterion is selected to determine a set of relatively optimal prediction parameters, and finally the model results A verification analysis was carried out. …”
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Prevalence of bed falls among inpatients in Iranian hospitals: A meta-analysis by Parvaneh Isfahani, Mohammad Sarani, Mina Salajegheh, Somayeh Samani, Aliyeh Bazi, Mahdieh Poodineh Moghadam, Fatemeh Boulagh, Mahnaz Afshari

“…The heterogeneity of the studies was tested using the I2 index and the meta-regression model at the 0.05 significance level. Finally, the Comprehensive Meta-Analysis software analyzed six articles that met the inclusion criteria. …”
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Local endoreduplication of the host is a conserved process during Phytomyxea–host interaction by Michaela Hittorf, Andrea Garvetto, Marianne Magauer, Martin Kirchmair, Willibald Salvenmoser, Pedro Murúa, Sigrid Neuhauser

“…We identified molecular signatures of endoreduplication in RNA-seq datasets of P. brassicae-infected Brassica oleracea and M. ectocarpii-infected Ectocarpus siliculosus.DiscussionCell cycle switch proteins such as CCS52A1 and B in plants, CCS52 in algae, and the protein kinase WEE1 in plants were upregulated in RNA-seq datasets hinting at a potential role in the phytomyxean-induced transition from mitotic cell cycle to endocycle. …”
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Chimonanthus nitens Oliv. leaves flavonoids alleviate hyperuricemia by regulating uric acid metabolism and intestinal homeostasis in mice by Wenya Meng, Lingli Chen, Kehui Ouyang, Suyun Lin, Yang Zhang, Jing He, Wenjun Wang

“…In addition, CLF repaired renal injury by significantly down-regulating mRNA and protein expressions of renal UA reabsorption-related proteins and up-regulating the mRNA and protein expressions of UA secretory-related proteins. Finally, CLF inhibited UA synthesis and promoted UA excretion to alleviate hyperuricemia. …”
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Spatial spread of sexually transmitted diseases within susceptible populations at demographic steady state by Carlos Castillo-Chavez, Bingtuan Li

“…It isshown that there exists a unique spreading speed (where thespreading speed is characterized as the slowest speed of a classof traveling waves connecting two endemic equilibria) at which theinfectious population carrying the invading stronger strainspreads into the space where an equilibrium distribution has beenestablished by the population with the weaker strain. Finally, wegive sufficient conditions under which an explicit formula for thespreading speed can be found.…”
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An efficient and lightweight detection method for stranded elastic needle defects in complex industrial environments using VEE-YOLO by Qiaoqiao Xiong, Qipeng Chen, Saihong Tang, Yiting Li

“…Precise integration of spatial structural and channel information further enhanced the model’s overall feature extraction capability. Finally, EIoU Loss replaced CIoU Loss to address bounding box aspect ratio variability and sample imbalance challenges, significantly improving overall detection task performance. …”
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Urban Road Change Detection using Morphological Processing by Ei Phyu Sin Win

“…The primary points in the model are the advancement of the picture, the segmentation of that picture, the application of the morphological operators, and finally the detection of the roadway network. Use Google Earth Pro to get the necessary data photos and search for road improvements. …”
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IAPSM’s Position Paper on Typhoid Vaccines for Adult Immunization in India by Kapil Goel, Madhur Verma, Nikita Sharma, Swayam Pragyan Parida, Anu Bhardwaj, Anuradha Nadda, Sahil Sharma, Arunima Sen, Jacob John, Adarsh Bansal, Madhu Gupta

“…IAPSM encourages members to take front-line efforts in their community health service areas, and finally appeals for the development of vaccines to cover a more extensive range of Salmonella infections so that control over typhoid can be strengthened.…”
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Failure Mechanism of Gob-Side Roadway under Overlying Coal Pillar Multiseam Mining by Hongwei Mu, Anhu Wang, Dazhao Song, Dongfang Su, Donghui Li

“…The analytical solutions of the vertical stress distribution and the plastic zone of the gob-side roadway under overlying coal pillars were obtained. Finally, the accuracy of the mechanical model was verified using numerical simulations. …”
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GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells by Fumiya Ito, Wakiko Iwata, Yoshihiro Adachi, Hiromi Sesaki, Miho Iijima

“…Further analysis revealed that GRHL2 upregulates the receptor tyrosine kinase HER3, and that HER3 knockdown similarly decreases the IC50 for erlotinib. …”
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Ultrasound-assisted enzyme extraction of Dendrobium Officinale polysaccharides: Extraction process, characterization, immunomodulatory effects by Hengpu Zhou, Yingjie Dong, Zhangyun Wu, Xi Peng, Meiqiu Yan, Suhong Chen, Guiyuan Lv

“…Subsequently, DOP was characterized using HPLC, SEM, and HPGPC. Finally, an immunocompromised mouse model induced by cyclophosphamide was adopted to evaluate the immunomodulatory effects. …”
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The problem of American Loans and Credits for Czechoslovakia in 1945–1948 by A. V. Zorin

“…A fundamental role in the establishment of a new US political course had Secretary of State James Byrnes’ decision, made in the fall of 1946, on the inadmissibility of providing assistance to countries that have taken anti-American positions. This approach was finally entrenched after the Communists coup in Czechoslovakia in February 1948, when the country entered the Soviet sphere of influence. …”
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The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture by Bulent Demir, Burak Onal, Sibel Ozyazgan, Esra Demir, Vedat Bakuy, Ahmet Gokhan Akkan

“…Additionally, immunofluorescence method was used to show the expression of NF-κB and ICAM-1. Finally, LDH levels were determined by the ELISA method to quantify cytotoxicity. …”
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La Ville botanique by Maria A. Villalobos H.

“…From then on, we shall understand those parameters on a defined ground which will have to be restored, not as a spot in the urban landscape, but as as the focal point of the urban landscape under reconstruction : the Botanical Garden of Maracaibo (1980) in Venezuela, by Roberto Burle Marx. Finally, we shall come back on the status of the notion of botanical garden. …”
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Carbonic anhydrase 2 mediates anti-obesity effects of black tea as thermogenic activator by Peng Ma, Jie Xiao, Biyu Hou, Ping He, Xinyu Yang, Yisa Wang, Zijing Wang, Tianshu Xu, Xiuying Yang, Xuan Zhu, Shasha Xiang, Song Li, Guanhua Du, Jian Ying, Guifen Qiang

“…Specifically, utilizing in silico approach of network pharmacology and molecular docking, we identified carbonic anhydrase 2 (CA2) in nitrogen metabolism as anti-obesity target of BTE and further elucidated that protein kinase B (AKT) signaling pathway linked CA2 and UCP1. …”
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Los estudios sociales de la tecnología en América Latina by Hernán Thomas

“…Otras líneas de investigación estuvieron ligadas a los estudios históricos internalistas y, hacia finales de los ochenta, a estudios sociológicos y antropológicos de enfoque constructivista. …”
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Antioxidant and Antimicrobial Activity of New Amide Compounds Containing Azo Group Using Dicyclohexylcarbodiimide (DCC) as Coupling Agent by Dania Mohammed Saleh, Bushra Kamel Al-Salami

“…The effectiveness of inhibiting fungi was also studied against Candida albicans by agar diffusion method. Finally, the antioxidant capacities of the prepared compounds were determined by using DPPH radical scavenging method. …”
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Nonlinear Pounding Analysis of Multispan and Simply Supported Beam Bridges Subjected to Strong Ground Motions by Hong-Yu Jia, Xian-Lin Lan, Nan Luo, Jian Yang, Shi-Xiong Zheng, Chao Zhang

“…Secondly, the natural vibration characteristic of the considered railway bridge is analyzed to prepare for the subsequent parameter analysis. Finally, the influence of three nonlinear parameters, i.e., stiffness of impact element, separation gap width of expansion joint, and bearing stiffness, on impact responses of bridge structures is studied. …”
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Research on the Deformation Law and Stress Distribution Characteristics of Overburden under the Influence of Multiple Faults by Yaobin Qi, Weijian Yu, Desun Yu, Hanxiao Guo, Bao Pan

“…The results showed that in the early stage of mining, F1 undergoes activation under the influence of the main roof weighting, leading to an increase in the degree of plastic damage to the coal seam and strata behind the working face, causing a redistribution of the behind abutment pressure. Finally, under the influence of the F1 barrier effect, the vast majority of the behind abutment pressure is transferred to the lower strata of F1, leading to a continuous increase in stress concentration there. …”
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