The Role of Phospholipase C Signaling in Macrophage-Mediated Inflammatory Response by Liqian Zhu, Clinton Jones, Gaiping Zhang

“…Recent studies have shown that some PLC isoforms are involved in multiple stages in TLR4-, CD14-, and FcγRs-mediated activation of nuclear factor kappa B (NF-κB), mitogen-activated protein kinase (MAPK), and interferon regulatory factors (IRFs), all of which are associated with the regulation of the inflammatory response. …”
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Tooth Profile Synthesis and Meshing Force Characteristic of Sinusoidal Double Generating-wave Pushrod Movable Tooth Transmission by Wang Lichuang, An Zijun

“…The maximum meshing force of the pushrod movable tooth on the center gear and the generator is gotten respectively. Finally， the calculation formula of the pressure angle of the transmission mechanism is conducted， and the variation law and influencing factors of pressure angle are analyzed. …”
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Probing aspects of extracellular vesicle associated AAV allows increased vector yield and insight into its transduction and immune-evasive properties by Ming Cheng, Demitri de la Cruz, Adam V. Crain, Paula Espinoza, Carrie Ng, Zachary C. Elmore, Aravind Asokan, Casey A. Maguire

“…Trans-expression of MAAP8 or MAAP9 increased yields of EV-AAV9 compared with the cis-expression of AAV9 Cap/AAV9 MAAP. Finally, we found that the capsid was required for efficient transduction of cultured cells by EV-AAV. …”
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Optimal System, Reductions, and Conservation Laws of a Nonlinear Damped Klein-Gordon- Fock Equation by Faiza Arif, F. M. Mahomed, F. D. Zaman, M. T. Mustafa

“…The graphs of the soliton solutions and traveling wave solutions are also presented. Finally, the conservation laws are identified via the partial Noether approach, leading to distinct cases with several subcases. …”
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Clinical advances in antibody-drug conjugates for hematological malignancies by TANG Sijie, MI Jianqing

“…Additionally, ADCs targeting different antigens such as CD123, CD19, CD20, receptor tyrosine kinase-like orphan receptor 1 (ROR1), and CD38 are undergoing clinical studies. …”
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Modern Fiber Art Creation Based on Traditional Hakka Hand Tie-Dyeing Process Based on Carbon Nanotube Nanomaterials by Fuying Zhang

“…It can be seen from the experimental data that the heat flow correlation function changes with time and gradually becomes stable and finally fluctuates around 0, which means that the model is in a stable state and the scheme is feasible. …”
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Application Research of New Cementitious Composite Materials in Saline Soil Subgrade Aseismic Strengthening by Shuai Huang, Yuejun Lyu, Yanju Peng

“…The research result showed that the saline soil solidified by our newly developed cementitious composite material showed compact internal structure and uniformly distributed soil particles; moreover, the new cementitious composite material exhibited a favourable solidifying effect on harmful ions in saline soil, and the Cl− trapping capacity of the new cementitious composite materials was stronger than that of cement. Finally, our developed cementitious composite material was applied to saline soil subgrade strengthening, and the displacement, acceleration, excess pore water pressure, and damage degree of the subgrade strengthening by our newly developed cementitious composite materials decreased remarkably; therefore, our newly developed cementitious composite material can improve the seismic behaviour of the saline soil subgrade and show potential future engineering application value.…”
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Prognostic Role of Platelet-to-Lymphocyte Ratio in Hepatocellular Carcinoma with Different BCLC Stages: A Systematic Review and Meta-Analysis by Wan-fu Lin, Mao-feng Zhong, Yu-ren Zhang, Huan Wang, He-tong Zhao, Bin-bin Cheng, Chang-quan Ling

“…A total of 297 potential studies were initially identified, and 9 studies comprising 2449 patients were finally enrolled to evaluate the association between the pretreatment PLR and clinical outcomes of overall survival (OS), disease-free survival (DFS), and event occurrence in patients with HCC in different BCLC stages. …”
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IL-17 Affects the Progression, Metastasis, and Recurrence of Laryngeal Cancer via the Inhibition of Apoptosis through Activation of the PI3K/AKT/FAS/FASL Pathways by Yang Song, Ming Yang, Hongjian Zhang, Yan Sun, Ye Tao, Huihui Li, Jing Zhang, Yuncheng Li, Jianming Yang

“…In addition, the time course expression of FAS and FASL was observed after stimulation and treatment with the IL-17 stimulator. Finally, in vitro experiments demonstrated that IL-17 functioned as an oncogene by inhibiting the apoptosis of LC cells via the PI3K/AKT/FAS/FASL pathways. …”
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Warped matrix-variate Gaussian processes with structured kernels for multi-step-ahead driving behaviour prediction by Seiya Takano, Tomohiko Jimbo

“…Additionally, from a practical standpoint, the proposed model is extended to constrain the support of the predictive distribution to a finite interval. Finally, we evaluated the performance of the proposed method using real data from 100 vehicles over up to nine months.…”
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Development of a Reduced Order Model-Based Workflow for Integrating Computer-Aided Design Editors with Aerodynamics in a Virtual Reality Dashboard: Open Parametric Aircraft Model-1... by Andrea Lopez, Marco E. Biancolini

“…The ROMs were exported as FMUs (Functional Mockup Units) to be easily managed in any environment. Finally, a VR design dashboard was created in the Unity environment, enabling the interaction with the geometric model in order to observe in a fully immersive and intuitive environment how each shape parameter affects the physics involved. …”
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The Detection of Soybean Bacterial Blight Based on Polarization Spectral Imaging Techniques by Jia Yi, Huilin Jiang, Yong Tan

“…The results show that the polarization spectral image can effectively identify the polarization characteristics of healthy soybean leaves and early bacterial blight in the field, and can distinguish the healthy leaves and the diseased leaves by obtaining the relative polarization reflectance of different areas in soybean leaves. Finally, the soybean disease species can be accurately diagnosed. …”
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Evaluation of the Influencing Factors of Using Underground Space of Abandoned Coal Mines to Store Hydrogen Based on the Improved ANP Method by Wang Liu, Peng Pei

“…First, the Apriori algorithm is applied to mine association rules between indicators, eliminate unnecessary influence relationships, simplify the network structure model, and optimize the ANP weight calculation results; second, the solution method of judgment matrix is improved with triangular fuzzy numbers, and the index weight is solved by fuzzy nine marks instead of the method of nine scale, which is convenient for experts to give the fuzzy scale while better reflecting the opinions of experts. Finally, the ANP algorithm is applied to rank the weights of the obtained influencing factors, discuss the main factors with higher weights, and analyze the feasibility of converting candidate coal mines into hydrogen storage facilities using the derived evaluation method in the case study. …”
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Recent plastic technologies development of basal texture control to improve the property of wrought Mg alloys-a review by Xiaoyu Feng, Lifei Wang, Xiang Chen, Kunkun Deng, Xiao Wang, Liuwei Zheng, Hongxia Wang, Qiang Zhang, Ho Kwon, Bin Xing, Kwang Seon Shin

“…The future development trends and challenges of Mg alloy plastic technology are finally proposed.…”
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A Universal Analysis Pipeline for Hybrid Capture-Based Targeted Sequencing Data with Unique Molecular Indexes by Min-Jung Kim, Si-Cho Kim, Young-Joon Kim

“…We focused mainly on the compatibility of the input and output of each tool. Finally, our laboratory built an analysis pipeline specialized for UMI-adopted data. …”
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An amplification mechanism for weak ELF magnetic fields quantum-bio effects in cancer cells by Amirali Zandieh, Seyed Peyman Shariatpanahi, Amir Abas Ravassipour, Javad Azadipour, Maryam Sadat Nezamtaheri, Zahra Habibi-Kelishomi, Mojtaba Ghanizadeh, Ali Same-Majandeh, Keivan Majidzadeh-A, Amir Taheri, Alireza Madjid Ansari, Mohammad Amin Javidi, Mohammad Mehdi Pirnia, Bahram Goliaei

“…We also observe the oscillatory behavior in the time-lapse fluorescence microscopy for 0.02 and 0.04 Hz magnetic fields. Finally, we investigate the dependence of the results on the field strength and propose a quantum spin-forbidden mechanism for the effect of magnetic fields on superoxide production in QO site of mitochondrial Complex III.…”
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Novel selective adsorption cooling materials for heating cigarettes by Chaojian Li, Xiaojuan You, Hongmei He, Huaibin Shi, Xin Gao, Wei Tang

“…Furthermore, the molecular simulation results found that the higher specific surface area and rich microscopic pore structure could increase the heat conduction area of the high-temperature flue gas, which enhanced the heat transfer effect of the flue gas. Finally, the periodic characteristic velocity pulsation destroyed the boundary layer formed by the fluid in the wall region, which increased the convective heat transfer effect between the fluid and the particles. …”
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Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathway by Chao Chen, Qiwu Wang, Jiwen Liu

“…Expression levels of insulin-like growth factor 1 receptor (IGF-1R) were determined by reverse transcription quantitative polymerase chain reaction (RT-qPCR) and western blotting. Phosphoinositide 3-kinase (PI3K), Akt, and forkhead box protein O1 (FOXO1) expression and phosphorylation were assessed by western blotting. …”
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Flexible switching method of control strategy for MMC-HVDC converter based on AC power grid strength by Maolan Peng, Lei Feng, Xiaoyu Hao, Meihui Sun, Wen Jiang, Chunyi Guo

“…This flexible control switching method ensures a smooth switching between different control strategies and causes a minimal disturbance to the overall system. Finally, a simulation model is established on the PSCAD/EMTDC platform, and the feasibility of the flexible control switching strategy for the MMC-HVDC system is verified. …”
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Dynamic Pricing under Cost Reduction in the Presence of Myopic and Strategic Consumers by Guangning Liu, Zhenzhong Guan, Hua Wang

“…In addition, with the increase of customer patience, not only strategic but also myopic consumers will buy less. Finally, the strategic properties moderate the pricing strategy in latter stage when there is a cost reduction. …”
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