Sustained Release of Prostaglandin E2 in Fibroblasts Expressing Ectopically Cyclooxygenase 2 Impairs P2Y-Dependent Ca2+-Mobilization by María Pimentel-Santillana, Paqui G. Través, Raquel Pérez-Sen, Esmerilda G. Delicado, Paloma Martín-Sanz, María Teresa Miras-Portugal, Lisardo Boscá

“…The inhibition of P2Y responses by PGE2 involves the activation of PKCs and PKD, a response that can be suppressed after pharmacological inhibition of these protein kinases. In addition to this, PGE2 reduces the fibroblast migration induced by P2Y-agonists such as UTP. …”
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Gamma Irradiation of Plukenetia volubilis L. Seeds Promotes Several Changes during Its Germination and Vegetative Growth by Mike Anderson Corazon-Guivin, Sofia Rengifo-Del Aguila, Angel David Hernández-Amasifuen, Víctor Manuel Arévalo-Rojas, Ronny Anthony Acosta-Córdova, Agustín Cerna-Mendoza, Thiago de Araújo Mastrangelo, Jorge Damian Valverde-Iparraguirre, Juan Carlos Guerrero-Abad

“…Also, the pattern of plant organ development changed as its gamma irradiation was increased. Finally, our analysis found that median lethal dose (LD50) for P. volubilis L. seeds is 618.78 Gy. …”
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Extraction of Spatial Distribution Characteristics of Jiangnan Urban Landscape under the Influence of Geomorphology by Shuhua Wang, Anhua Qin

“…From the perspective of spatial variability, the main features of traditional landscape construction in Jiangnan are analyzed through three levels: the characteristics of the process of humanized landscapes evolving into natural landscapes, the comparative analysis of similarities and differences in the construction of cities and towns, and the characteristics of the system of regional landscape construction. Finally, the changes in the landscape pattern of the region under the influence of globalization are analyzed through the changing characteristics of landscape architecture.…”
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La Jeune Grecque de David d’Angers ou le rêve brisé by Philippe Durey

“…While David d’Angers’ interest in Botzaris and the Greek cause, and the way he came up with his idea and his attachment to his statue are fairly well-documented, part of the history of this work has remained in the dark: the exact date of its execution, the knowledge of it in France before it was sent to Greece, the circumstances of its sending, the contacts with the Greeks, David’s place in the philhellenic movement, his sentimental and phantasmatic relationship with Greece, his plans to leave and set up a school of sculpture there, and finally the brutality of his disappointment in 1852. …”
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Logs for acid-base chemistry: illustrating the potential of multidisciplinary learning support interventions from the third space by Joshua Wang, Elise Kenny

“…Observations made during the workshop suggest that the intervention was able to efficiently improve acid-base calculation confidence in students from all attending cohorts.  Finally, the broader benefits of subject specialist third space staff in higher education are discussed in light of the case study findings. …”
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Éléments pour une théorie biologique du sujet by Lionel Simonneau

“…Indeed, the third approach focuses to a part of the world, which is captured by the subject, without any knowing, through his sensitive organs or his emotions, which could feed his behaviours and decisions. Finally, we end by an interrogation: how is any theory of the subject, especially those developed in this particular issue of this journal, getting on when it is applied not to the current man but to the so-called “enhanced human”, in a transhumanist society, where biological, physical, cognitive, emotional characteristics are hugely modified by the synthetic biology and the nanotechnologies?…”
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A Piecewise Linearization Based Method for Crossed Frequency Admittance Matrix Model Calculation of Harmonic Sources by Youhang Yang, Shaorong Wang, Mingming Shi, Xian Zheng

“…Furthermore, taking single-phase and three-phase bridge rectifiers as examples, CFAM analytical models under intermittent and continuous load current conditions are established, respectively, and the unified harmonic models for both conditions are summarized. Finally, case studies of rectifier harmonic sources under varying circuit control parameters and supply voltage distortions are conducted through Matlab/Simulink and experiments. …”
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Extraction of Features due to Breathing Crack from Vibration Response of Rotated Blades considering Tenon Connection and Shroud Contact by Faming Yang, Yongmin Yang, Haifeng Hu, Fengjiao Guan, Guoji Shen, Suiyu Chen, Zifang Bian

“…Next, the stiffness of the blade trunk with a breathing crack is analyzed. Finally, the vibration response of blade trunks with the occurrence of breathing crack is analyzed in time and frequency domains by numerical simulation. …”
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A Meta-Analysis for Association of Maternal Smoking with Childhood Refractive Error and Amblyopia by Li Li, Ya Qi, Wei Shi, Yuan Wang, Wen Liu, Man Hu

“…Potential publication bias was finally examined by Egger’s test. Results. A total of 9 articles were included in this meta-analysis. …”
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Recognition and Simulation of Exercise Mode Based on Energy Consumption Model by Yulei Li

“…Then, the motion recognition algorithm is tested, which can effectively identify the common movement patterns of primary and middle school students. Finally, the linear relationship between the estimation results of the model and the calculation results of Meijer is analyzed. …”
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Livestock Breeders’ Conflicts in the Steppe Rangelands of Naâma Region (Western Algeria) by Youcefi Ahmed Toufik, Marouf Abderrazak

“…The solution consists in cleaning up the steppe against illegal monopolies, accompanied by awareness-raising activities for a better awareness of residents to change their bad behavior. Finally, the competent authorities are required to find alternatives to enable farmers to carry out their activities properly. …”
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Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity by Peng Wang, Xin Li, Xuran Li, Weiwei Yang, Shun Yu

“…This was supported by the observations that phosphorylated α-syn oligomers entered neurons, rapidly increased accumulated thioflavin S-positive inclusions, and induced a series of metabolic changes that included activation of polo-like kinase 2, inhibition of glucocerebrosidase and protein phosphatase 2A, and reduction of ceramide levels, all of which have been shown to promote α-syn phosphorylation and aggregation. …”
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Current biomarkers of prostate cancer by I. A. Aboian, E. N. Fedotova, A. N. Shevchenko, S. M. Pakus, A. Yu. Maximov, E. V. Filatova, I. A. Khomutenko, Е. F. Komarova, N. K. Guskova

“…And with the increase in their availability, finally, the possibility of an individual approach to the appointment of treatment for men with prostate cancer appears on the horizon. …”
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LW-YOLO11: A Lightweight Arbitrary-Oriented Ship Detection Method Based on Improved YOLO11 by Jianwei Huang, Kangbo Wang, Yue Hou, Jiahe Wang

“…Secondly, the interaction between the spatial information of remote sensing images and the semantic information of low-resolution features of ships is realized by using the cross-stage partial stage. Finally, the GSConv module is introduced to minimize the loss of semantic information on ship features during transmission. …”
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Procrustes' Bed Metaphor: Understanding the Problem of Creativity and Innovation in the Human Resources of Iran's State-Owned Enterprises by Mohsen Imeni, Ali Sorourkhah

“…Questionnaires were distributed among experts and experts in charge of five big-size state-owned companies, and finally, 124 questionnaires were analyzed descriptively.Findings: The research findings show that the Procrustes bed has become a company desk in Iran's state-owned enterprises. …”
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Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood by Heiner Falkenberg, Teja Falk Radke, Gesine Kögler, Kai Stühler

“…In the presented publications, CD34-positive cells were isolated from cord blood and expanded for up to 7 days in media supplemented with stem cell factor (SCF), thrombopoietin (THPO), interleukin 6 (IL-6), and fms-related tyrosine kinase 3 ligand (FLT3lg). At days 3 and 7, expanded cells were harvested and analyzed by flow cytometry and quantitative proteomics. 2970 proteins were identified, whereof proteomic analysis showed 440 proteins significantly changed in abundance during ex vivo expansion. …”
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Sigma Virus (DMelSV) Incidence in Lines of Drosophila melanogaster Selected for Survival following Infection with Bacillus cereus by Meghan L. Bentz, Eve A. Humphrey, Lawrence G. Harshman, Marta L. Wayne

“…Later eclosing progeny were also less likely to be infected than earlier eclosing progeny, indicating a relationship with development time. Finally, there was a significant interaction between the timing of collection and the sex of the progeny, such that later eclosing males were the most resistant group. …”
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Harnessing the AI/ML in Drug and Biological Products Discovery and Development: The Regulatory Perspective by Fahimeh Mirakhori, Sarfaraz K. Niazi

“…We discuss the promises of responsible data-driven AI, challenges and related practices adopted to overcome limitations, and our practical reflections on regulatory oversight. Finally, the paper outlines a path forward and future opportunities for lawful ethical AI. …”
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An improved FMEA for sustainable risk management in the agri-food industry sector: A mini-review by Izzum Wafi'uddin, Imam Santoso, Arif Hidayat, Naila Maulidina Lu’ayya, Annisa’u Choirun

“…The mini-review is systematically organized by collecting articles, selecting them based on publication year and keywords, screening titles, screening for inclusion, assessing quality through a full-text review, extracting, and analyzing data, and finally reporting the findings. An analysis of 20 papers from 2010 to 2024 was conducted, examining a variety of frameworks. …”
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Multiobjective Optimization Design for Structural Parameters of TBM Disc Cutter Rings Based on FAHP and SAMPGA by Laikuang Lin, Yimin Xia, Dun Wu

“…According to the characteristics of this model, a self-adaptive multipopulation genetic algorithm (SAMPGA) is utilized to solve the optimization problem, and the Fuzzy analytical hierarchy process (FAHP) is employed to calculate weight coefficients for multiple objectives. Finally, the applicability of the proposed method is demonstrated through a case study in a TBM project. …”
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