ArfGAP with the SH3 Domain, Ankyrin Repeat and PH Domain 1 Inversely Regulates Programmed Death-Ligand 1 Through Negative Feedback of Phosphorylated Epithelial Growth Factor Recept... by Chiba N, Menju T, Shimazu Y, Toyazaki T, Sumitomo R, Miyamoto H, Tamari S, Nishikawa S, Date H

“…Multiple analysis of receptor tyrosine kinases (RTKs) was conducted using a semi-comprehensive RTKs assay.Results: We found that AMAP1 inversely regulated PD-L1 expression. …”
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Non-cancerous CT findings as predictors of survival outcome in advanced non-small cell lung cancer patients treated with first-generation EGFR-TKIs. by Pakorn Prakaikietikul, Pattraporn Tajarenmuang, Phumiphat Losuriya, Natee Ina, Thanika Ketpueak, Thanat Kanthawang

“…<h4>Purpose</h4>To identify non-cancerous factors from baseline CT chest affecting survival in advanced non-small cell lung cancer (NSCLC) treated with first-generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors (EGFR-TKIs).<h4>Methods</h4>Retrospective study of 172 advanced NSCLC patients treated with first-generation EGFR-TKIs as a first-line systemic treatment (January 2012 to September 2022). …”
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Chromium "(VI)" phytoremediation using Azolla pinnata: effects on Vicia faba growth, physiology, cytogenetics, and gene expression profiling by Elham R. S. Soliman, Kareem Moustafa, Mohamed Khamis, Zeinab A. Shedeed

“…Furthermore, the gene expression levels of both the PM H+-ATPase and the calcium-dependent protein kinase CDPK5 were upregulated in response to Cr, despite the fact that the expression level was altered in a dose- and concentration-dependent manner by Azolla treatment. …”
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Work performance, physiological and hemato-biochemical responses in working buffalo with different load weights by Visoky Paján-Jiménez, Fernando D. Pazmiño-Rodríguez, Patricia Roldán-Santiago, Cristian Larrondo-Cornejo, Anna Dutro-Aceves, Luis A. de la Cruz-Cruz

“…Physiological (respiratory rate, pulse, heart rate, and rectal temperature) and biochemical (glucose, lactate dehydrogenase, creatine kinase, and total protein) parameters, as well as blood cell count (white blood cell, neutrophils, lymphocytes, monocytes, eosinophils, and basophils), increased after work regardless of weight load (p<0.001). …”
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Clinical characteristics and prognosis of amyopathic dermatomyositis patients with interstitial lung disease: insights from a retrospective cohort by Yanan Ying, Tingting Wu, Long Wang, Yun Zhang, Yiming Yu, Zaichun Deng, Qunli Ding

“…The ADM with nonspecific interstitial pneumonia (NSIP) group (n = 46) presented increased haemoglobin (125.93 ± 12.91 g/L, p = 0.005), creatine kinase-MB (15.19 ± 8.58 U/L, p < 0.001), and partial pressure of oxygen (93.08 ± 26.20 mmHg, p = 0.003) levels and decreased β2-microglobulin (2.61 ± 1.21 mg/L, p = 0.039) levels compared to the control-NSIP group (n = 92). …”
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Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts by Kelley Weinfurtner, David Tischfield, George McClung, Jennifer Crainic, John Gordan, Jing Jiao, Emma E. Furth, Wuyan Li, Erena Tuzneen Supan, Gregory J. Nadolski, Stephen J. Hunt, David E. Kaplan, Terence P.F. Gade

“…No differences were observed in tumor engraftment or growth latency in subcutaneous tumors, but orthotopic tumors required implantation at 2 rather than 4 weeks post-humanization for successful engraftment. Finally, utilizing adult bone marrow instead of fetal livers enabled partial HLA-matching to HCC tumors but required more CD34+ cells. …”
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Determinants of 5-year survival in patients with advanced NSCLC with PD-L1≥50% treated with first-line pembrolizumab outside of clinical trials: results from the Pembro-real 5Y glo... by Mieke Van Hemelrijck, Salvatore Grisanti, Avinash Aujayeb, Martin Forster, Giannis Mountzios, Andrea Napolitano, Bruno Vincenzi, Joachim G J V Aerts, Marina Garassino, Valter Torri, Solange Peters, Alex Friedlaender, Alfredo Addeo, Giuseppe Lo Russo, Roberto Ferrara, Diego Signorelli, Alessandro Russo, So Yeon Kim, Jarushka Naidoo, Scott Gettinger, Heather Wakelee, Martin Sebastian, Mark Awad, Abdul Rafeh Naqash, Alessio Cortellini, Raffaele Giusti, Michele De Tursi, Federica Zoratto, Marco Russano, Rita Chiari, Biagio Ricciuti, Andrea De Giglio, Alain Gelibter, Giuseppe Tonini, Amin H Nassar, Alessandra Curioni-Fontecedro, Eleni Karapanagiotou, Emilio Bria, Jack Bell, Paolo Bironzo, Joao V Alessi, Alessandro Morabito, David J Pinato, Francesco Passiglia, Carlo Genova, Francesca Mazzoni, Alessandro Inno, Francesco Grossi, Luca Cantini, Lorenza Landi, Luigi Della Gravara, Margarita Majem, Uma Mukherjee, Federica Biello, Alessandro Leonetti, Annalisa Guida, Marianna Macerelli, Gabriele Minuti, Giulio Metro, Thomas Newsom-Davis, Eleni Josephides, Andrea Camerini, Elisa Roca, David O’Reilly, Mingjia Li, Laura Mezquita, Teresa Gorría, Claudia A M Fulgenzi, Lauren Young, Joel W Neal, Javier Baena, Francesco Pantano, Jacobo Rogado, Mary Jo Fidler, Teresa Beninato, Federica Pecci, Alessandro Di Federico, Kazuki Takada, Leonardo Brunetti, Talal El Zarif, Laura Moliner, Alberto Servetto, Sukumar Kalvapudi, Sai Yendamuri, Edoardo Garbo, Giuseppina Rita Di Fazio, Monica Loza, Ritujith Jayakrishnan, Michele Montrone, Nichola O Awosika, Bartlomiej Tomasik, Maximilian Rost, Isabelle Monnet, Francesco Agustoni, Artur Katz, Dwight Hall Owen, Michele Ghidini, Armida D’Incecco, Gianpaolo Spinelli, Monica Verrico, Manuel Dupont, Rafael Di Marco Barros, Diego Luigi Cortinovis, Chiara Bennati, Frank Aboubakar Nana, Anne-Marie Dingemans, Taher Abu Hejleh

“…To further assess the reproducibility of clinical trial results, we reconstructed the “KN024 look-alike” cohort by excluding patients with an Eastern Cooperative Oncology Group-performance status (ECOG-PS)≥2, those requiring corticosteroids with doses ≥10 mg of prednisolone/equivalent, patients with positive/unknown epidermal growth factor receptor/anaplastic lymphoma kinase genotype, and those with pre-existing autoimmune disease. …”
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Perancangan Aplikasi Computer based Test (CBT) Psikotes Berbasis Website by Sistha Putri Hemawati, Hanna Prillysca Chernovita

“…Untuk mengetahui bakat dan minat seseorang, sifat dan karakter seseorang, kepintaran hingga kecerdasan  seseorang tidak hanya bisa dengan dilihat melainkan perlu melakukan psikotes sebagai tolak ukur. …”
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Çağdaş Bir Anakronizm Örneği: Ehl-i Hadis Ekolü Temsilcilerinden İhsan İlâhî Zahîr’in Şîa Karşıtlığı Üzerine Bir İnceleme by Gülşen Yağır Ahmetoğlu

“…Zahîr, eserlerinin çoğunu Arapça yazmış, yazılarında ve yaptığı konuşmalarında özellikle Şiîler, Kâdiyânîler ve Birelvîler hakkında yaptığı eleştiriler, bu kesimlerin düşmanlığına neden olmuş ve 1987 yılında Minâr-ı Pâkistan’a yakın bir yerde yaptığı bir konuşma esnasında suikasta uğrayarak ağır yaralanmış ve tedavi için götürüldüğü Riyad’daki hastanede vefat etmiştir. …”
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Decolonization Projects by Cornelius Ewuoso

“…A. (ed.) 19370. [15] Dina Zoe Belluigi & Gladman Thondhlana 2019. ‘Why mouth all the pieties?’ …”
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Dynamic changes and future trend predictions of the global burden of anxiety disorders: analysis of 204 countries and regions from 1990 to 2021 and the impact of the COVID-19 pande... by Si Chen, Wei Huang, Min Zhang, Yan Song, Chunshan Zhao, Hongwei Sun, Yanyu Wang, Jihong Wang, Yali Sun, Lei Zhou, Yan Zhu, HongYuan Wang, ZhengYang Xu, YuRui Bai, Cheng Chang

“…Furthermore, path analysis was utilized to investigate the impact pathways between the COVID-19 pandemic and anxiety disorders. Finally, a Bayesian age-period-cohort (BAPC) model was employed to predict the prevalence trends of anxiety disorders from 2022 to 2050. …”
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Study on the status of liver function abnormalities and its related factors in patients with severe mental disorders in Shanghai community by ZHANG Yixuan, CHEN Chunmei, ZHU Youwei, ZHU Yi, HE Siyuan, LIU Yanli, WANG Na, CAI Jun, XIE Bin, ZHANG Weibo

“…Binary logistic regression analysis was used for multivariate analysis of the status of abnormal liver function, and the effects of mental disorder types and medication status on liver function were analyzed, simultaneously.ResultsA total of 7 251 patients with SMD were finally included into this study, and the rate of liver function abnormality was 22.7%, of which 694 cases (9.6%) had ALT abnormality and 1 084 cases (14.9%) had TBil abnormality. …”
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Estimating Suitable Areas for Dry Almond (Amygdalus communis L.) Cultivation Development in Fars Province using Geographic Information System (GIS) by Ayatollah Karami, Alireza Salehi, Vida Aliyari

“…After fuzzy mapping and combining fuzzy scores with the weights obtained from the AHP analysis, the Fuzzy overlay algorithm was used to overlay different thematic layers (climatic, topographic, socio-economic, environmental adaptation). Finally, the map estimating the extent of suitable areas for almond cultivation was classified into five classes.Results and Discussion In this research, suitable areas for almond cultivation have been identified using Analytic Hierarchy Process (AHP) and GIS. …”
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Characteristics of the Volunteer Service Management System for National Parks in the United Kingdom by Tianyi REN, Chuanbo HONG, Yinglin WANG

“…Then the research summarizes the characteristics of volunteer service management in each national park and combines similar characteristics, based on which the characteristics of the universal volunteer service management system for national parks in the UK are finally summarized. Meanwhile, on the basis of literature review, this research searches relevant official data on the first batch of national parks announced in China, analyzes such contents as management documents, activity management, and personnel recruitment management, and compares the same horizontally with the volunteer service management system for national parks in the UK so as to analyze the shortcomings of the volunteer service management system for national parks in China and put forward corresponding suggestions.ResultsThe research finds that the 14 national parks in the UK have sound volunteer service management policies, management system structures and volunteer recruitment websites, as well as open and transparent volunteer screening mechanisms and volunteer feedback channels. …”
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The Role of Potassium Phosphite in Enhancing the Activity of Defense Enzymes in Rice Infected by Sheath Blight by Milad Habibi Daronkolaei, Mohammad Ali Tajick Ghanbary, Valiollah Babaeizad, Heshmatollah Rahimian, Ali Dehestani

“…Subsequently, the seeds were germinated and transferred to plastic pots filled with sterile soil. Finally, the pots were moved to the growth chamber. …”
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Performance evaluation of four cascade impactors for airborne ultrafine-particle (UFP) collection: the influence of particle type, concentration, mass, and chemical nature by E. Eckenberger, A. Mittereder, N. Gawlitta, N. Gawlitta, J. Schnelle-Kreis, J. Schnelle-Kreis, M. Sklorz, D. Brüggemann, R. Zimmermann, R. Zimmermann, A. C. Nölscher

“…</p> <p>The mass concentrations of the semi-volatile markers (PA, TA, and Levo) decreased on average from the PENS to the ultraMOUDI, then to the 120R MOUDI-II, and finally to the ELPI. We attributed this tendency to the following two effects. (1) Evaporation losses of these markers were likely driven by the pressure drop within the impactor, which increased from the PENS to the ELPI. (2) Despite the applied coating, bounce-off might have affected the smallest impactors (i.e., the PENS and ultraMOUDI) the most as they have fewer stages for retaining larger particles and fragments.…”
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On the Exponential Atom-Bond Connectivity Index of Graphs by Kinkar Chandra Das

“…We present several relations between <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mi>e</mi><mi mathvariant="script">ABC</mi></msup><mrow><mo>(</mo><mo>Υ</mo><mo>)</mo></mrow></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>A</mi><mi>B</mi><mi>C</mi><mo>(</mo><mo>Υ</mo><mo>)</mo></mrow></semantics></math></inline-formula> of graph <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mo>Υ</mo></semantics></math></inline-formula>. Finally, we provide a conclusion summarizing our findings and discuss potential directions for future research.…”
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homeRNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort studyResearch in... by Fang Yun Lim, Hannah G. Lea, Ashley M. Dostie, Soo-Young Kim, Tammi L. van Neel, Grant W. Hassan, Meg G. Takezawa, Lea M. Starita, Karen N. Adams, Michael Boeckh, Joshua T. Schiffer, Ollivier Hyrien, Alpana Waghmare, Erwin Berthier, Ashleigh B. Theberge

“…This is followed by a rapid induction of many interferon-stimulated genes (ISGs), concurrent to onset of viral shedding and increase in nasal viral load and symptom burden. Finally, elevated baseline expression of antimicrobial peptides was observed in exposed-uninfected individuals. …”
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Phasic and periodic change of drought under greenhouse effect by Yang Li, Zhicheng Zheng, Yaochen Qin, Haifeng Tian, Zhixiang Xie, Peijun Rong

“…In future, it will be necessary to focus on a sensitivity analysis of drought indices with regard to climate change. Finally, although this study calculated the SPEI using meteorological data provided by China’s high-density observatory network, deviations and uncertainties were inevitable in the point-to-grid spatialization process. …”
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Educide amid conflict: the struggle of the Palestinian education system by Dalal Iriqat, Rula Alousi, Tahani Z. Aldahdouh, Alaa AlDahdouh, Iman Dankar, Dima Alburai, Mohamed Buheji, Abdo Hassoun

“…The study’s qualitative approach may also limit the ability to quantify the full extent of destruction and long-term impacts on educational outcomes. Finally, the challenging political environment may affect the availability and reliability of certain sources, potentially leading to gaps in comprehensive data on Gaza’s educational infrastructure and human resource losses. …”
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