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21861
The Influence of Depression, Anxiety, and Stress on Ageism Among Undergraduates: Mediating Roles of Life Satisfaction, Gratitude, and Prosociality
Published 2025-01-01“…It then examines the predictive effects of depression, anxiety, and stress (DAS) on ageism, accounting for these socio-demographic factors. Finally, the study explores how DAS influences ageism both directly and indirectly through life satisfaction, gratitude, and prosociality.Design and Settings: A cross-sectional study conducted at 11 higher education institutions in Jiangxi, China.Participants: A total of 1,213 undergraduates participated in the study between July and August 2024. …”
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21862
Advances in machine learning applications to resource technology for organic solid waste
Published 2025-03-01“…Another strategy is the use of reinforcement learning and transfer learning, which effectively address dynamic environments and small datasets, respectively. Finally, this work highlights the need for future research to focus on the integration of ML models with real-time process monitoring and control systems. …”
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21863
3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors
Published 2025-01-01“…The ten most promising compounds were screened based on the IC50 values and tested for molecular docking. Finally, the binding stability and dynamic behavior of these compounds with MAO-B receptors were analyzed by molecular dynamics simulation (MD).ResultsThe 3D-QSAR model showed good predictive ability, with a q2 value of 0.569, r2 value of 0.915, SEE of 0.109 and F value of 52.714 for the COMSIA model. …”
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21864
Le temple polygonal de la rue Lecointre à Reims/Durocortorum
Published 2022-11-01“…It represents a first for this region and thus confirms the hypothesis that this animal may have been imported and kept in parks. Finally, the establishment of a chalk quarry, in the immediate vicinity of the temple during the first half of the 3rd c. …”
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21865
Research on time–frequency characteristics of electromagnetic signals from coal and rock blasting based on DBO-VMD filtering
Published 2025-03-01“…The DBO-VMD achieves a signal-to-noise ratio about two times that of the EMD. Finally, we conducted a statistical analysis of the entropy, energy, bispectrum, and time–frequency domain characteristics of pure electromagnetic signals associated with coal–rock ruptures. …”
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21866
Factors associated with the discontinuation of modern contraceptive methods among lactating women in nine West African high-fertility countries: findings of the most recent demogra...
Published 2025-01-01“…Moreover, women who were not sexually active (aPR = 2.11; 95% CI [1.75–2.54]; p < 0.001) and those who wanted children within two subsequent years (aPR = 1.84; 95% CI [1.36–2.48]; p < 0.001) were more likely to discontinue contraception. Finally, method discontinuation varied by country, with women in Gambia, Guinea, Mauritania, and Mali more likely to discontinue a modern contraceptive method than those living in Burkina Faso. …”
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21867
ECG‐based epileptic seizure prediction: Challenges of current data‐driven models
Published 2025-02-01“…Secondly, the prediction was attempted in pseudo‐prospective conditions. Finally, visualized HRV data, clinical metadata, and results were correlated. …”
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21868
A Model H5N2 Vaccine Strain for Dual Protection Against H5N1 and H9N2 Avian Influenza Viruses
Published 2024-12-01“…Furthermore, we demonstrated that M2e-specific immune responses, difficult to induce with inactivated vaccines, can be effectively elicited with live vaccines, suggesting a strategy to enhance M2e immunogenicity in whole influenza virus vaccines. <b>Conclusions:</b> Finally, the successful development of the model rH5N2 vaccine strain is described; this strain provides dual protection, has potential applicability in regions where avian influenza is endemic, and can be used to promote the development of versatile H5N2 recombinant vaccines for effective avian influenza control.…”
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21869
South to south collaboration: advancing quality of abortion care through health care professionals exchange program
Published 2025-01-01“…Thematic analysis, following initial coding and inter-coder agreement, was employed to identify key themes from the interviews. Finally, triangulation of qualitative and quantitative data was performed to provide a comprehensive understanding of the program’s impact. …”
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21870
A Dynamic Adaptive Ensemble Learning Framework for Noninvasive Mild Cognitive Impairment Detection: Development and Validation Study
Published 2025-01-01“…To address the challenges (eg, the curse of dimensionality and increased model complexity) posed by high-dimensional features, we developed a dynamic adaptive feature selection optimization algorithm to identify the most impactful subset of features for classification performance. Finally, the accuracy and efficiency of the classification model were improved by optimizing the combination of base learners. …”
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21871
Genomic characteristics of ST6115 carbapenem-resistant Klebsiella pneumoniae coharboring blaNDM-1 and blaIMP-4
Published 2025-02-01“…Annotation and analysis of the genome enabled the identification of the plasmid structure and the comparative analysis of the genetic background. Finally, the conjugation transfer experiment was conducted to assess the transferability of the plasmid pHD8428-NDM-IMP.ResultsA comparable phylogenetic analysis revealed that ST6115 HD8428 and the majority of ST17 strains (9/12) were clustered on the same clade, which suggests a close relationship between two ST types. …”
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21872
Chemistry of Hydrothermally Destabilized Rare-Metal and Radioactive Minerals in Deformed A-Type Granite in the Vicinity of Nugrus Shear Zone, South Eastern Desert, Egypt
Published 2024-12-01“…Also, the intimate relationship of sulfides with destabilized rare-element minerals indicates the destabilization of these minerals during the hydrothermal stage under reduced conditions. Finally, the proposed paragenetic sequence suggests that most ore minerals are magmatic or hydrothermal primarily. …”
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21873
Testing an Electronic Patient-Reported Outcome Platform in the Context of Traumatic Brain Injury: PRiORiTy Usability Study
Published 2025-01-01“…ResultsIn total, 9 participants completed a single usability testing session using Atom5, including 4 men, 4 women, and 1 nonbinary individual; 4 participants were under 55 years old, and 6 had their TBI <10 years ago. Finally, 8 participants used an Android device. The platform included measures for anxiety (Generalized Anxiety Disorder-2 item), depression (Patient Health Questionnaire-2), posttraumatic stress disorder (Posttraumatic Stress Disorder checklist 2), and TBI-specific quality of life (Traumatic Brain Injury – Quality of Life Short form) and a total of 26 questions. …”
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21874
Autoimmune glial fibrillary acidic protein astrocytopathy misdiagnosed as intracranial infectious diseases: case reports and literature review
Published 2025-01-01“…Anti-tuberculosis treatment was ineffective. Finally, with positive GFAP IgG in CSF, she was diagnosed with A-GFAP-A. …”
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21875
The effect of nursing care provided to coronary intensive care patients according to their circadian rhythms on sleep quality, pain, anxiety, and delirium: a randomised controlled...
Published 2025-02-01“…Considering the sound levels in the environment, the first-night decibel mean was significantly higher in the intervention group than in the control group (first-night decibel mean: intervention group 56.58 ± 2.43 dB vs. control group 54.51 ± 2.41 dB, p < 0.05). Finally, the smartwatch data show no significant difference in sleep times between groups (p < 0.05), but the intervention group had more deep and total sleep, while the control group had less deep sleep. …”
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21876
Characterization of Listeria monocytogenes strains isolated from soil under organic carrot farming
Published 2025-01-01“…The use of natural fertilizers during organic farming can be a source of pathogens, including L. monocytogenes in the soil and finally in vegetables and fruits. The aim of this study was to assess the prevalence of L. monocytogenes in soil samples from organic carrot crops (Poland) and to characterize the tested strains. …”
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21877
Enhanced Antitumor Efficacy and Reduced Toxicity in Colorectal Cancer Using a Novel Multifunctional Rg3- Targeting Nanosystem Encapsulated with Oxaliplatin and Calcium Peroxide
Published 2025-01-01“…The in vivo targeting effect as well as antitumor efficacy were determined in HCT116 tumor-bearing mice. Finally, the acute toxicity of Rg3-Lip-OXA/CaO2 was investigated in ICR mice to explore its safety.Results: The XRD and XPS analyses confirmed the successful synthesis of CaO2 nanoparticles. …”
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21878
Efficacy and Safety of Ultrasound-Guided Radiofrequency Treatment for Chronic Pain in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Published 2020-01-01“…In addition, the outcomes were blindly assessed in the meta-analysis from all studies according to evaluation of bias, which could affect the reality of the data. Finally, most of the studies only provided short follow-up times, so we could not analyze the long-term effectiveness of ultrasound-guided RF in the treatment of patients with KOA. …”
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21879
The anticancer properties, cell-cycle cytotoxicity and apoptosis of cissus rotundifolia, trema orientalis, and buddleja polystachya with ocular applications
Published 2025-02-01“…Additionally, a clonogenic assay was performed to measure tumor cell survival and subsequent proliferative capacity after drug exposure was conducted for the most active extract(s) and finally western blotting was used to determine the expression change of the two selected proteins (survivin and CCND1) in order to determine the exact mechanistic features of the most promising plant extract. …”
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21880
Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study
Published 2025-01-01“…Additionally, Kaplan-Meier curves were used to compare the cumulative incidence of cardiovascular and all-cause mortality across different metabolic statuses. Finally, the predictive value of eGDR for mortality was assessed using receiver operating characteristic curves.ResultsDuring an average follow-up of 115 months, a total of 6,906 (15.01%) participants experienced all-cause mortality, with 1,798 (3.91%) deaths attributed to cardiovascular causes. …”
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