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21621
Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial
Published 2025-02-01“…A total of 124 patients was finally analyzed. The primary outcome was 28-day, in-ICU mortality. …”
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21622
A predictive risk‐scoring model for survival prognosis of multiple myeloma based on gain/amplification of 1q21: Experience in a tertiary hospital in South‐Western China
Published 2024-09-01“…The model's discriminative ability was evaluated using the AUC in both the training and validation sets. Finally, we compared the performance of the +1q21‐involved risk with the established R‐ISS and R2‐ISS models. …”
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21623
Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study
Published 2025-01-01“…MR-PRESSO was used to detect and correct outliers by excluding anomalous instrumental variables. Finally, we supplemented our analysis with methods such as Bayesian Weighted Mendelian Randomization (BWMR), Maximum-Likelihood, Lasso, Debiased Inverse Variance Weighted, and Contamination Mixture to establish a robust and compelling causal relationship.ResultsAfter accounting for reverse causality, horizontal pleiotropy, and various methodological corrections, Bifidobacterium kashiwanohense, GCA-900066755 sp900066755, Geminocystis, and Saccharofermentanaceae exhibited strong and robust causal effects on CRC. …”
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21624
Effectiveness of Virtual Reality Technology Interventions in Improving the Social Skills of Children and Adolescents With Autism: Systematic Review
Published 2025-02-01“…At the same time, nonimmersive VR stands out in terms of lower cost and flexibility, making it more appropriate for basic skill interventions for people with LFA. Finally, while VR technology positively enhances social skills, some studies have reported potential adverse side effects. …”
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21625
Evaluation of two-dimensional ultrasound fetal thymus size in correlation to infection parameters in pregnancies complicated with preterm premature rupture of membranes
Published 2023-12-01“…Group 1 had a positive correlation between Thymus perimeter and APGAR score of the neonates (r=0.658, P=0.002), Thymus perimeter and birth weight (r=0.741, P<0.001), Thymus transverse diameter and APGAR score of the neonates (r=0.741, P<0.001), and finally Thymus transverse diameter and birth weight (r=0.734, P<0.001). …”
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21626
Photo-Fenton Degradation of RB5 Dye in Aqueous Solution Using Fe Supported on Mexican Natural Zeolite
Published 2019-01-01“…The optimal RB5 dye degradation was achieved at RB50=100 mg/L in the presence of MNZ/Fe=0.2 g/L, H2O2=3 g/L and pH=2.5 where the highest discoloration and chemical oxygen demand removal were 93 and 70.5 at 180 min. Finally, the kinetic reaction was evaluated as a pseudo-first-order kinetics with an apparent rate constant (kapp) of 0.0225 min-1 at latest conditions.…”
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21627
Understanding “Alert Fatigue” in Primary Care: Qualitative Systematic Review of General Practitioners Attitudes and Experiences of Clinical Alerts, Prompts, and Reminders
Published 2025-02-01“…From an Organization perspective, the need for training on the use and benefits of CRs was highlighted. Finally, in the context of the Wider system and their Embedding Over Time, suggestions included sharing best practices for CR use and involving GPs in their design. …”
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21628
Prevalence of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in Ethiopia: A Systematic Review and Meta-Analysis
Published 2021-01-01“…Estimation of outcome measures at 95% confidence interval was performed using Der-Simonian-Laird’s random-effects model. Finally, results were presented via text, figures, and tables. …”
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21629
Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress
Published 2025-01-01“…Second, under cell wall stress, Whi7 was specifically recruited to SBF-target promoters, independent of the increase in its protein levels or cell cycle stage. Finally, we found that Whi7 protein instability further increased during cell wall stress and that Whi7 degradation triggered advanced cell cycle re-entry. …”
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21630
Ecological networks construction and optimization in the Longdong Loess Plateau: The advantages of self-organizing map and complex networks
Published 2025-01-01“…Furthermore, we compared the ENs before and after optimization to identify the benefits of the SOM. Finally, we apply the complex network topology edge-adding strategy to enhance the robustness of network. …”
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21631
Extracellular vesicles (EVs) in seminal plasma of buffalo bulls possess spermatozoa specific fertility associated proteins and enzymes
Published 2023-11-01“…We observed that protein cargo was successfully assimilated with sperm. Finally, LC-MS/MS-based high throughput proteome was performed to identify the differential abundance of protein cargo in seminal EVs of contrasting fertility bulls. …”
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21632
Association between exposure to tobacco information through mass media, smoking households and secondhand smoke exposure in adolescents: Survey data from South Korea
Published 2024-01-01“…In addition, regression models revealed that exposure to cigarette advertising in magazines (β=0.131; 95% CI: 0.097–0.166), networks (β=0.151; 95% CI: 0.127– 0.175), convenience stores (β=0.061; 95% CI: 0.035–0.087), and supermarkets (β=0.133; 95% CI: 0.108–0.158) is associated with SHS exposure in adolescents. Finally, our study showed stronger ties between SHS exposure, family smoking, and tobacco ads in girls. …”
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21633
Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains
Published 2025-02-01“…We also identified genes whose requirements were subspecies, lineage, and isolate-specific. Finally, by correlating TnSeq profiles, we identified 19 previously uncharacterized genetic networks in Mab. …”
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21634
Efficacy and safety of ketamine and esketamine in reducing the incidence of postpartum depression: an updated systematic review and meta-analysis
Published 2025-02-01“…We extracted PPD occurrence rate, PPD score, pain score and side effects. Finally, a meta-analysis was conducted using RevMan software. …”
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21635
Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer
Published 2025-01-01“…Notably, we detect copy number variants predominantly within luminal acinar cells in prostate tumors, suggesting a bias in their cell type of origin, as well as a larger field of transcriptomic alterations in non-tumor cells. Finally, we observe that luminal acinar tumor cells in treatment-naïve prostate cancer display heterogeneous androgen receptor (AR) signaling activity, including a split between AR-positive and AR-low profiles with similarity to PrU-like states. …”
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21636
Pengembangan Media Pembelajaran Video Animasi 2 Dimensi dengan Model ADDIE pada Mata Pelajaran Teknik Pengolahan Audio dan Video Kelas XII Multimedia SMKN 12 Malang
Published 2022-12-01“…The development of learning media is carried out using the ADDIE model with the following stages: (1) Conducting student character analysis, media analysis and learning analysis; (2) Designing character designs, media scenarios and designing instrument sheets; (3) Performing the animation video development stage, audio recording and video finalization; (4) Implementing face-to-face and online learning activities; and (5) Conducting learning evaluation activities and testing the validity of media and materials to 3 media experts and 2 material experts. …”
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21637
L’utilisation du bois dans les aménagements portuaires antiques de Narbonne/Narbo Martius (Aude)
Published 2020-12-01“…AD; - the phases of reconstruction/repair, especially during Late Antiquity ; - finally, the remains of a probable unloading machine. …”
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21638
Clinical manifestations, para-clinical features and outcome of Iranian adults with respiratory syncytial virus (RSV) infection: a report from hospitalized patients
Published 2025-02-01“…Notably, biochemical and inflammatory markers such as CRP, ESR, and LDH were significantly elevated beyond the normal range. Finally, five patients (13.9%) who received intensive care treatments died. …”
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21639
Dissolution, Solubility, and Stability of the Basic Ferric Sulfate-Arsenates [Fe(SO4)x(AsO4)y(OH)z·nH2O] at 25–45°C and pH 2–10
Published 2021-01-01“…For the dissolution of the sample FeSAsOH–1 [Fe(SO4)0.27(AsO4)0.73 (OH)0.27·0.26H2O] at 25–45°C and initial pH 2, all constituents preferred to be dissolved in the order of AsO43− > SO42− > Fe3+ in 1–3 h, in the order of SO42− > AsO43− > Fe3+ from 1–3 h to 12–24 h, and finally in the order of SO42− > Fe3+ > AsO43−. The released iron, sulfate, and arsenate existed dominantly as Fe3+/Fe(OH)2+/FeSO4+, HSO4−/SO42−/FeSO4+, and H3AsO40/H2AsO4−, respectively. …”
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21640
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease
Published 2025-02-01“…Transcription factors (GATA2, POU2F2, NFKB1, etc.) can regulate the expression of biomarkers. Finally, we discovered that all biomarkers could bind to MLT with a strong binding energy. …”
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