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21361
Which combination of medical expulsive therapy is more effective for treatment of distal ureteral stone in adults? A systematic review and network meta-analysis
Published 2025-01-01“…The combination MET of α-blockers with PDE-5 inhibitors (MD: -3.8, CI=-7.0, -0.5) showed significantly lower SET compared to α-blockers alone. Finally, combination MET of α-blockers with PDE-5 inhibitors (MD:1.0, CI = 0.4,1.7) and nifedipine with corticosteroids (MD:1.2, CI = 0.4,1.9) showed a significant decrease in analgesia use. …”
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21362
Modelación numérica del concreto simple con elementos finitos mediante la teoría de la plasticidad y la función de fluencia de Hu y Schnobrich Numerical modeling of the simple conc...
Published 2012-12-01“…The constitutive model presented in this paper was implemented in the nonlinear analysis finite element program with open source HYPLAS (de Souza Neto et al. 2008) and the post-process was performed using GiD (CIMNE 2008). Finally we present the comparison of the structural response of panels subjected to forces contained in its plane tested experimentally by Kupfer and others (1969), against the numerical simulation using the proposed model. …”
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21363
A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer
Published 2025-02-01“…Single-cell analysis was conducted to investigate cellular interactions associated with the immune-determinant gene module. Finally, immunofluorescence staining for CD8, CD45, and CXCR4 was performed on human GC tissue samples. …”
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21364
Evaluation of Rapeseed Leave Segmentation Accuracy Using Binocular Stereo Vision 3D Point Clouds
Published 2025-01-01“…Furthermore, the study results show that combining plane fitting with pass-through filtering effectively removes the ground point cloud noise, while statistical filtering successfully denoises outlier noise points generated during scanning. Finally, using the region-growing algorithm during the seedling stage with a normal angle threshold set at 5.0/180.0* M_PI and a curvature threshold set at 1.5 helps to avoid the under-segmentation and over-segmentation issues, achieving complete segmentation of rapeseed seedling leaves, while the LCCP clustering method fully segments rapeseed leaves at the bolting stage. …”
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21365
Systematic review and bayesian network meta-analysis: comparative efficacy and safety of six commonly used biologic therapies for moderate-to-severe Crohn’s disease
Published 2025-01-01“…A random-effects model was performed with rankings according to the surface under cumulative ranking curve (SUCRA) probability. Finally, we completed sensitivity and consistency analyses, and evaluated the certainty of evidence through GRADE working group guidance.ResultsWe identified 22 and 20 RCTs for induction and maintenance therapy, respectively. …”
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21366
Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells
Published 2025-01-01“…Conclusion Quercetin is greatly cytotoxic in oral cancer cells, triggering cells undergoing apoptosis and ROS-mediated cell death, possessing S and G2/M cell cycle arrest properties, and exhibiting anti-metastatic activities. Finally, this discovery opens up a wide range of possibilities for developing an anti-oral cancer drug and further investigating its effectiveness in vivo and in clinical trials as an alternative cancer treatment.…”
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21367
Predicting the Degree of Coronary Artery Stenosis Through Retinal Vascular Characteristics and Minimal Clinical Information
Published 2025-02-01“…The area under the curve (AUC) for logistic regression modeling with the Gensini Score binarized (dichotomized into two categories based on a cutoff of 4 points) as the dependent variable and fundus vascular characteristics as the independent variable was 0.59 ± 0.05 (95% CI). …”
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21368
Saussurea gossypiphora extracts reduce inflammation by reversing inflammatory cytokine levels in in-vitro and in-vivo
Published 2025-02-01“…Effect of MESGD on inflammasome pathway was studied by performing ELISA for IL-1β, TNF-α and confirmed by immunoblotting for NLRP3 and Caspase 1 in THP1 cells. Finally, RAW 264.7 cells treated with LPS were assessed for the synthesis of Nitric Oxide to confirm anti-inflammatory activity of MESGD. …”
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21369
Association between domain-specific physical activity and triglyceride‑glucose (TyG) index among US adults: Evidence from NHANES 2007–2018
Published 2025-01-01“…Furthermore, the stratified analysis found that the correlation between LT-MVPA and TyG index was stronger in females, those with higher family incomes, and non-smokers. Finally, mediation analyses indicated a significant joint mediation effect of BMI on the relationships between LT-MVPA (≥ 150 min/week) and the TyG index, accounting for 31.48% of the total effect. …”
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21370
Airborne Levels of Lung Carcinogens at an Ascon Manufacturing Site
Published 2020-04-01“…The drying process removes moisture from the aggregate and maintains the required temperature for combining the aggregate, asphalt, and additives into ascon during the mixing stage. Finally, the ascon is disgorged from an outlet on the mixing machine and loaded onto dump trucks. …”
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21371
A deep learning-based method for the intelligent identification of the quantity of coals flushed out during borehole hydraulic flushing
Published 2025-01-01“…The CIoU loss function was replaced with the SIoU loss function to accelerate the matching between prediction and ground truth boxes. Finally, the improved YOLOv8n algorithm was validated using a self-built dataset. …”
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21372
Economic burden of chronic obstructive pulmonary disease and post-tuberculosis sequelae in low- and middle-income countries: a database compiled from a systematic review and meta-a...
Published 2024-07-01“…The costs were lower in lower middle-income countries compared with upper middle-income countries. Finally, considerable economic burden was attributable to smoking and air pollution.Conclusion The review and the CD-CPTB database give a thorough snapshot of the current evidence of the costs and economic burden of COPD and post-TB diseases. …”
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21373
18F−Prostate−Specific Membrane Antigen PET/CT imaging for potentially resectable pancreatic cancer (PANSCAN−2): a phase I/II study
Published 2025-01-01“…TBR was defined as the ratio between SUVmax of the primary tumor divided by SUVmax of the aortic blood pool. Finally, tracer uptake on PET was correlated to tissue expression of PSMA in surgical specimens. …”
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21374
Analysis of Fatigue Crack Propagation of an Orthotropic Bridge Deck Based on the Extended Finite Element Method
Published 2019-01-01“…Moreover, based on the extended finite element method (XFEM), the static crack and dynamic crack propagation in this critical position were analyzed. Finally, thermoelastoplastic analysis was carried out on the connection of the U-rib and deck with a length of 500 mm to obtain the residual stress, and then the results of residual stress were introduced into the segmental model to further study its influence on the evolution of fatigue crack propagation. …”
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21375
Photosynthetic Pigments with Potential for a Photosynthetic Antenna: A DFT Analysis
Published 2019-01-01“…From frequency calculations, IR spectra were obtained for combinations. Finally, excited-state computations were carried out to acquire UV-Vis spectra of the combinations. …”
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21376
The Mycoplasma hyopneumoniae protein Mhp274 elicits mucosal and systemic immune responses in mice
Published 2025-02-01“…The levels of IFN-γ, IL-4, and IL-17, in the supernatants of splenocytes and in serum were measured, and the mRNA levels of three cytokines in splenocytes were analyzed. Finally, lymphocyte proliferation after stimulation with corresponding proteins or crude extract of M. hyopneumoniae J strain was assessed.ResultsWe successfully constructed recombinant bacteria expressing rMhp170, rMhp274, and rMhp336. …”
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21377
Design and Development of a Web‐Based Registry for Outpatient Rehabilitation: A Delphi Multi‐Disciplinary, Expert Consensus Study
Published 2025-01-01“…Basic information comprised 12 subcategories of demographic details, socioeconomic information, referral information, service provider information, follow‐up information, death information, history, past medical history, environmental factors, treatment measures, rehabilitation measures, and assessment of body systems; specialized information included four subcategories of optometry information, audiology information, physiotherapy information, and speech therapy information. Following the finalization of the MDS, a web‐based registry for outpatient rehabilitation was created. …”
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21378
Advanced Machine Learning to Predict Coronary Artery Disease Severity in Patients with Premature Myocardial Infarction
Published 2025-01-01“…In addition, we used decision curve analysis (DCA) to assess the clinical validity of the XGBoost prediction model. Finally, an online calculator based on the XGBoost was established to measure the severity of coronary artery lesions in PMI patients Conclusions: In summary, we established a novel and convenient prediction system for the severity of lesions in PMI patients. …”
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21379
The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention
Published 2023-01-01“…The patients (N = 236) who were diagnosed with dilated cardiomyopathy or valvular heart disease without coronary artery stenosis, those with prior history of CABG or valvular surgery (N = 59), those who presented ST-segment elevated myocardial infarction (STEMI), those with a CAD and SYNTAX score of ≦ 22 (N = 175), those who received emergent CABG for coronary perforation (N = 3), and those who had NYHA class ≦ 2 (N = 65) were excluded. Finally, 116 patients with reduced LVEF and those who had a SYNTAX score >22, who received CABG (N = 47) and PCI (N = 69), were recruited for this study.Results. …”
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21380
Daily time series of 12 human thermal stress indices in Greece, aggregated at commune level (1998–2022)Zenodo
Published 2025-02-01“…The attribution of heat stress indices at the commune level (also referred as municipalities or municipal units), which is the lowest level of government within the organizational structure in Greece, enhances the usefulness of the data for statistical analysis against other parameters, such as epidemiological or socio-economic data, which are often available at this level. Finally, the dataset can support educational purposes, providing a practical example of climate data analysis and geospatial statistics applications.…”
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