Suggested Topics within your search.
Suggested Topics within your search.
- Academic writing 1
- Advertising 1
- Agriculture 1
- Autonomy and independence movements 1
- Branding (Marketing) 1
- Calculus 1
- Communication in marketing 1
- Curricula 1
- Curriculum planning 1
- Cytodiagnosis 1
- Decolonization 1
- Dissertations, Academic 1
- Economic policy 1
- Education 1
- Electric circuit analysis 1
- Electric network analysis 1
- Electronic Health Records 1
- English language 1
- Entrepreneurship 1
- Film adaptations 1
- Foreign economic relations 1
- Grammar, Comparative and general 1
- History 1
- History and criticism 1
- International business enterprises 1
- LANGUAGE ARTS & DISCIPLINES / General 1
- LANGUAGE ARTS & DISCIPLINES / Linguistics / General 1
- LANGUAGE ARTS & DISCIPLINES / Linguistics / Syntax 1
- Life change events 1
- Literary style 1
-
20821
Fluctuations of anisotropic flow in Pb+Pb collisions at s NN $$ \sqrt{{\mathrm{s}}_{\mathrm{NN}}} $$ = 5.02 TeV with the ATLAS detector
Published 2020-01-01“…These results provide new information to disentangle flow fluctuations from the initial and final states, as well as new insights on the influence of centrality fluctuations.…”
Get full text
Article -
20822
A Heterogeneous Ensemble Learning Method Combining Spectral, Terrain, and Texture Features for Landslide Mapping
Published 2025-01-01“…Then, we construct a heterogeneous ensemble learning landslide recognition method, which combines the advantages of fully convolutional network, U-Net, and attention U-Net base classifiers to fully learn the multidimensional features of landslides. Finally, we evaluate the performance of the landslide recognition framework in the Bailongjiang River Basin complex scenes. …”
Get full text
Article -
20823
hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts
Published 2023-01-01“…Having observed that the extracellular-signal-regulated kinase (ERK) pathway in intestinal fibrosis can be inhibited by hucMSC-Ex, we treated intestinal fibroblasts with an ERK inhibitor to emphasize the potential target of ERK phosphorylation in the treatment of IBD-associated intestinal fibrosis. …”
Get full text
Article -
20824
Aggressive Papillary Thyroid Carcinoma Presenting with Metastasis to the Pancreas
Published 2022-01-01“…Surgical resection can be curative and can be followed by radioactive iodine ablation therapy if cancer cells show avidity. Tyrosine kinase inhibitors can be used in refractory disease. …”
Get full text
Article -
20825
Opérculos de Bolma rugosa en la necrópolis del Neolítico Medio de Bòbila Madurell (Barcelona, España)
Published 2024-12-01“…Estas estructuras con opérculos se datan entre finales del V milenio y la primera mitad del IV milenio a. …”
Get full text
Article -
20826
Effect of Admission Hyperglycemia on Short-Term Prognosis of Patients with Non-ST Elevation Acute Coronary Syndrome without Diabetes Mellitus
Published 2021-01-01“…However, there were significant differences in the incidences of multivessel disease, renal insufficiency, pump failure, and emergency percutaneous coronary intervention, and levels of high-sensitivity C-reactive protein, cardiac troponin T, and creatine kinase isoenzyme MB among the three groups (p<0.05 for all). …”
Get full text
Article -
20827
AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription
Published 2024-12-01“…Methods The study utilized databases such as PhosphositePlus, TRANSFAC, CHEA, GPS 5.0, and TCGA, along with experimental techniques including Western Blot, co-IP, in vitro kinase assay, construction of lentiviral overexpression and silencing vectors, immunoprecipitation, modified proteomics, immunofluorescence, ChIP-PCR, EdU assay, Transwell assay, and scratch assay to investigate the effects of AKT1-induced Notch1 phosphorylation on cell proliferation, invasion and migration in vitro, as well as growth and epithelial-mesenchymal transition (EMT) in vivo. …”
Get full text
Article -
20828
Does Adiponectin Act as an Antiangiogenic Factor in B-Cell Chronic Lymphocytic Leukemia?
Published 2009-01-01“…Furthermore, patients with higher levels of adiponectin had a more favorable biological profile as defined by a lower number of both CD38− (r=−0.294; P=.02) and ZAP-70+ (r=−0.285; P=.04). Finally, we evaluated the presence of adiponectin in B-CLL cells at gene expression level. …”
Get full text
Article -
20829
CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models
Published 2025-02-01“…Pyruvate kinase isoform M2 (PKM2) is a multifunctional enzyme capable of transitioning between monomeric, dimeric, and tetrameric states, with its oligomeric equilibrium playing a pivotal role in tumour progression and survival. …”
Get full text
Article -
20830
JWST Imaging of Edge-on Protoplanetary Disks. IV. Mid-infrared Dust Scattering in the HH 30 Disk
Published 2025-01-01“…We also find a tension in the disk inclination angle inferred from optical/near-IR and millimeter observations, with the latter being closer to exactly edge-on. Finally, we report the first detection of the proper motion of an emission knot associated with the mid-IR collimated jet detected by combining two epochs of our MIRI 12.8 μ m observations.…”
Get full text
Article -
20831
Unveiling the toxicity of JWH-018 and JWH-019: Insights from behavioral and molecular studies in vivo and vitro
Published 2025-01-01“…JWH-018, but not JWH-019, activated the CB1R-dependent extracellular signal-regulated kinase 1 and 2 (ERK1/2) pathway in vivo and in vitro. …”
Get full text
Article -
20832
Body composition and physical performance of mountain bike athletes
Published 2025-01-01“…Participants performed the standing long jump and handgrip strength tests, to assess their strength of the lower and upper limbs, respectively. Finally, we measured the completion time of a Mountain Bike Marathon, with the distance of 75 km). …”
Get full text
Article -
20833
Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis
Published 2025-01-01“…In addition, rapamycin improved AD-MSC immunoregulatory functions by promoting the expression of immunosuppressive factors, such as IDO1, PTGS2 and also CD274 (encoding PD-L1). Finally, RNA sequencing analysis showed that in the presence of rapamycin, AD-MSCs displayed improved chondroprotective regenerative effects on co-cultured OA chondrocytes. …”
Get full text
Article -
20834
Development and validation of an integrated model for the diagnosis of liver cirrhosis with portal vein thrombosis combined with endoscopic characters and blood biochemistry data:...
Published 2025-12-01“…The validation got an AUC of 0.890 (95% CI, 0.831–0.934), A nomogram tool was finally established for application.Conclusion Blood test combined endoscopic characters could preliminarily predict the liver cirrhosis with portal vein thrombosis for cirrhotic patients undergoing endoscopic examination.…”
Get full text
Article -
20835
Pollen contamination and mating structure in maritime pine (Pinus pinaster Ait.) clonal seed orchards revealed by SNP markers
Published 2023-08-01“…All parental genotypes from the seed orchards contributed to the offspring as pollen parents, but differences in paternal reproductive success were detected. Finally, the overall self-fertilization rate was estimated at 5.4%, with considerable variability between genotypes (from 0% to 26%). …”
Get full text
Article -
20836
Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model: endophenotypic target for ASD
Published 2025-01-01“…Additionally, Sholl analysis revealed a reduction in dendritic branching and neuronal projection length in both mouse and human CLCN4 KD neurons. Finally, the decreased phosphorylation of SYNAPSIN and expression of PSD95 along with dendrite abnormalities were restored after Risperidone treatment. …”
Get full text
Article -
20837
A High-Salt Diet Disturbs the Development and Function of Natural Killer Cells in Mice
Published 2020-01-01“…Moreover, it was also found that the ability of NK cells to secrete CD107a and IFN-γ in HSD-fed mice was decreased following stimulation with RMA-S and YAC-1 tumor cells. Finally, the underlying molecular mechanism was evaluated, and it was found that HSD increased the production of reactive oxygen species (ROS) by NK cells, while the expression of CD122 was decreased, suggesting that HSD downregulates CD122 expression in NK cells via ROS signaling, thereby reducing the responsiveness to IL-15 and ultimately inhibiting NK cell function. …”
Get full text
Article -
20838
Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
Published 2007-07-01“…Furthermore, focal adhesion and Src family kinases, which propagate integrin-linked signaling and downstream cytoskeletal rearrangements, are shown to be required for FimH-dependent bacterial invasion of target host cells. …”
Get full text
Article -
20839
Next generation sequencing uncovers multiple miRNAs associated molecular targets in gallbladder cancer patients
Published 2023-11-01“…Panther analysis revealed the insulin-like growth factor (IGF)-mitogen activated protein kinases (MAPK) cascade, p38 MAPK pathway, p53 pathway, and FAS (a subgroup of the tumor necrosis factor receptor) signaling pathway as highly enriched among dysregulated miRNAs. …”
Get full text
Article -
20840
Urinary Proteome and Exosome Analysis Protocol for the Discovery of Respiratory Diseases Biomarkers
Published 2025-01-01“…., miR-16-5p, miR-21-5p, miR-146a-5p, and miR-215-5p) in urine exosomes by RTqPCR. Finally, we detected 333 miRNAs using Nanostring, 15 of them up-regulated in T2<sup>high</sup> asthma (N = 4) compared to T2<sup>low</sup> asthma (N = 4) and healthy subjects (N = 4). …”
Get full text
Article