Genetic polymorphisms of muscular fitness in young healthy men. by Tomas Venckunas, Hans Degens

“…Five of the studied polymorphisms (activin- and adreno-receptors, as well as myosine light chain kinase 1) in a group of one to three combined with body height, age and/or group explained up to 20.4% of the variation of muscle function. …”
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Hybrid dung beetle optimization based dimensionality reduction with deep learning based cybersecurity solution on IoT environment by Amal K. Alkhalifa, Nuha Alruwais, Wahida Mansouri, Munya A. Arasi, Mohammed Alliheedi, Fouad Shoie Alallah, Alaa O. Khadidos, Abdulrhman Alshareef

“…Besides, intrusions are detected using the attention bidirectional recurrent neural network (ABiRNN) model. Finally, an artificial rabbits optimization (ARO) based hyperparameter tuning process is performed, enhancing the overall classification performance. …”
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Abnormal Circadian Modification of Aδ-Fiber Pathway Excitability in Idiopathic Restless Legs Syndrome by Catello Vollono, Giacomo Della Marca, Elisa Testani, Anna Losurdo, Daniela Virdis, Diana Ferraro, Valerio Brunetti, Paolo M. Rossini, Domenica Le Pera, Salvatore Mazza, Massimiliano Valeriani

“…We recorded scalp laser-evoked potentials (LEPs) to stimulation of different sites (hands and feet) and during two different time conditions (daytime and nighttime). Finally, we compared the results with a matched control group of healthy subjects. …”
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Relationship between accelerometer-measured physical activity and depressive symptoms in hemodialysis patients with comorbid diabetes mellitus: a multicenter cross-sectional study by Ruiting Liang, Ruiting Liang, Xiaoyu Chen, Gaowa Siqin, Zhixin Zhang, Zhixin Zhang, Shumei Zhang, Lihua Li, SarNa Talin, Qi Guo

“…ObjectiveThe objective of this study was to examine the association between accelerometer-derived moderate-to-vigorous physical activity (MVPA) and depressive symptoms in hemodialysis patients with and without type 2 diabetes mellitus (T2DM).MethodsThis cross-sectional study finally included 450 maintenance hemodialysis patients (male 281, average age 62 years) from seven dialysis centers in Shanghai, China. …”
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Application of new external cooling cycles in technological scheme of helium extraction and natural gas liquefaction by M. Mehrpooya, A. V. Zaitsev, A. O. Lisovtsov

“…It shows that the cost of the product obtained in the normal MFC cycle and in the MFC cycle using an absorption refrigeration machine is $0,1939 and $0,2069 per kg of LNG, respectively. Finally, on the basis of such economic factors as the cost of electricity and the cost of the product, the efficiency of the new cycle was analyzed…”
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Effect of Laryngeal Mask Airway Insertion on Intraocular Pressure Response: Systematic Review and Meta-Analysis by Mohammed Suleiman Obsa, Zewde Zema kanche, Robera Olana Fite, Tilahun Saol Tura, Bulcha Guye Adema, Aseb Arba Kinfe, Melkamu Worku kercho, Kebreab Paulos chanko, Getahun Molla Shanka, Atkuregn Alemayehu Lencha, Gedion Asnake Azeze, Lolemo Kelbiso Hanfore, Nefsu Awoke Adulo, Blen Kassahun Dessu, Getahun Dendir Wolde, Shimelash Bitew Workie

“…A total of 47 research papers were reviewed, of which, six studies were finally included in this systematic review and meta-analysis. …”
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Preliminary Experiment on the Effect of 18% Substitute Salt on Home Blood Pressure Variability in Hypertensives by Jing Li, Lisha Mu, Huakun Rao, Yangfeng Wu, Hao Wang, Hongbing Tao, Lihong Mu

“…The present study is a phase I clinical trial involving 43 hypertensives in which the effect of 18% sodium substitute salt on the home blood pressure variability (BPV) was observed for 8 weeks with weekly follow-up. Finally, 4 patients were lost, and 39 patients completed the intervention and were included in the analysis. …”
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Characterization of subcutaneous and visceral de-differentiated fat cells by Yan Li, Houyu Zhang, Carlos F. Ibáñez, Meng Xie

“…Moreover, HFD deposits epigenetic changes in DFAT cells and ASPCs that are not reversed after returning to CD. Finally, combining genetic lineage tracing and single cell/nucleus RNA sequencing, we demonstrate the existence of DFAT cells in inguinal and epididymal adipose depots in vivo, with transcriptomes resembling late-stage ASPCs. …”
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Spatial and temporal characteristics and driving mechanisms of recreational ecosystem services supply-demand mismatch in rapidly urbanizing areas: Evidence from the Yangtze River D... by Ruien Tang, Guolin Hou, Yueyi Chen, Xiao Liu, Shaoying Chu, Li Li

“…The regression coefficients were significantly heterogeneous in space. Finally, the influence processes of county-level and city-level drivers were discussed, and the establishment of a three-level transmission mechanism of “grid-county-city” was proposed to achieve the sustainable management of recreational resources.…”
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A medical insurance fund operation performance evaluation system under the DRG payment mode reform by Zijian Wang, Zijian Wang, Zijian Wang, Weifu Chang, Weifu Chang, Aijing Luo, Aijing Luo, Aijing Luo

“…It develops an innovative performance evaluation system for medical insurance funds utilizing the AHP-EWM-FCE evaluation method. Finally, it explores the key influencing factors by applying the Tobit regression model.ResultsAs the reform of DRG payment methods has advanced, the operational performance scores related to the management, fundraising, utilization, and satisfaction of DRG medical insurance funds have consistently improved. …”
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Evolving trends in the prevalence and treatment of ankylosing spondylitis in Korea from 2010 to 2023: a population-based study by Yu-Seon Jung, Soo-Kyung Cho, Se Rim Choi, Sun-Young Jung, Yoon-Kyoung Sung

“…The introduction of interleukin-17 and Janus kinase (JAK) inhibitors, particularly as second- and third-line therapies, marked a significant development. …”
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Differential expressed genes (DEGs) and differential alternative splicing genes (DASs) revealed the common pathologic mechanism of three bacterial pathogens to American eels (Angui... by Zihao Chen, Guanghua Sun, Songlin Guo

“…These DASs predominantly enriched in five GO terms associated with “RNA processing” and “binding”, and they were also significantly associated with two KEGG pathways of “Spliceosome” and “NOD-like receptor signaling pathway”. Finally, the analysis of protein-protein interactions identified 72 out of 332 common DASs. …”
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Role of the Btk-PLCγ2 Signaling Pathway in the Bone Destruction of Apical Periodontitis by Lina Wang, Hong Zhang, Ming Dong, Meina Zuo, Shuo Liu, Ying Lu, Weidong Niu

“…Studies have shown that the Bruton tyrosine kinase- (Btk-) phospholipase Cγ2 (PLCγ2) signaling pathway plays an important role in bone absorption, but it is unknown whether it plays a role in apical periodontitis bone destruction. …”
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A machine learning-based model for predicting paroxysmal and persistent atrial fibrillation based on EHR by Yuqi Zhang, Sijin Li, Peibiao Mai, Yanqi Yang, Niansang Luo, Chao Tong, Kuan Zeng, Kun Zhang

“…We built a prediction model for AF using three machine learning methods. Finally, the significance of each variable was analyzed by Shapley additive explanations method. …”
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Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer: a prospective cohort study by Zeyin Hu, Mengna Luo, Ruoying He, Zhenming Wu, Yuying Fan, Jia Li

“…Univariate and multivariate regression analyses were used to identify independently associated risk factors of PICC-RVT and develop a risk prediction model. 275 patients were finally included for data analysis, and 18 (6.5%) developed PICC-RVT. …”
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Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome by Xinlei Sun, Shuang Qu, Fenglian Zhou, Fujie Shi, Yunfei Wu, Lin Gu, Minghui Liu, Zhen Bian, Lei Shi, Zhihong Liu, Yuan Liu, Ke Zen

“…In a mouse model of Stx1/2-positive EDL933 infection-induced HUS, the presence of Stx2-positive monocytes in peripheral blood and infiltrated kidney tissues was observed. Finally, depleting monocytes through the usage of a CD14 neutralizing antibody or blocking monocyte chemotaxis via inhibition of CCL2 notably mitigates kidney injury and dysfunction caused by lipopolysaccharide (LPS)/Stx2 treatment. …”
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Vertical Profile of Wind Diurnal Cycle in the Surface Boundary Layer over the Coast of Cotonou, Benin, under a Convective Atmosphere by Hagninou E. V. Donnou, Aristide B. Akpo, Clément A. Kouchadé, Basile B. Kounouhewa, Guy H. Hounguè, Gbènoukpo F. Nonfodji, Julien Djossou

“…The average wind speed during this cycle is therefore evaluated to 8.07 m·s−1 for August which is the windiest month and to 4.98 m·s−1 for the least windy month (November) at 60 m of the ground. …”
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Evaluation of Serum Leucine-Rich Alpha-2 Glycoprotein as a New Inflammatory Biomarker of Inflammatory Bowel Disease by Tetsuhiro Yoshimura, Keiichi Mitsuyama, Ryosuke Sakemi, Hidetoshi Takedatsu, Shinichiro Yoshioka, Kotaro Kuwaki, Atsushi Mori, Shuhei Fukunaga, Toshihiro Araki, Masaru Morita, Kozo Tsuruta, Hiroshi Yamasaki, Takuji Torimura

“…Disease activity was assessed clinically and endoscopically. Finally, LRG gene expression in the PBMCs from a different cohort (41 patients with UC, 34 patients with CD, and 30 healthy controls) was examined. …”
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Investigation of intracellular signals generated by γ-interferon and IL-4 leading to the induction of class II antigen expression by S. Vassiliadis, N. Kyrpides, D. Stravopodis, M. Grigoriou, I. Athanassakis, J. Papamatheakis

“…Determination of the pathway followed by various cytokines can be achieved using specific inhibitors which include theophylline (TPH), TMB-8 and W7 that hinder calmodulin binding to Ca2+; sphingosine (SPH), H7 and staurosporine that inhibit protein kinase C (PKC) activation; and mevalonate (MEV) or the anti-p21ras antibody which block G-proteins. …”
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Numerical Prediction of Fatigue Life for Landing Gear Considering the Shock Absorber Travel by Haihong Tang, Panglun Liu, Jianbin Ding, Jinsong Cheng, Yiyao Jiang, Bingyan Jiang

“…Only 84 FE simulations are needed to efficiently obtain the fatigue stress spectra from the ground load spectra. Finally, according to the material S-N curve and Miner’s damage accumulation criterion, evaluate the fatigue life of the Main Fitting. …”
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