Comprehensive Analysis of the Immune Response to SARS-CoV-2 Epitopes: Unveiling Potential Targets for Vaccine Development by Huixiong Deng, Yanlei Li, Gefei Wang, Rui Li

“…Furthermore, using Shannon entropy for sequence conservation analysis and structural network-based methods identified candidate epitopes that are highly conserved and evolutionarily constrained in SARS-CoV-2 and other zoonotic coronaviruses. Finally, the population coverage of T cell epitopes was analyzed. …”
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Identification of urothelial cancer-associated 1 (UCA1) as a diagnostic biomarker of pre-eclampsia via regulating microRNA-16 and its downstream signaling pathway by Ye-Hong Xv, Wei Gao, Liao-Jv Wang

“…Moreover, UCA1 was identified as a sponge of miR-16, while PAPP-A mRNA was identified as a virtual target gene of miR-16. Finally, a negative regulatory relationship was observed between the expression of miR-16 and UCA1 or PAPP-A, while the expression of UCA1 and PAPP-A were positively related. …”
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Failure and development height of overlying rock of a water flowing fracture in goaf under a karst aquifer by Lulin Zheng, Xiong Liu, Qing Qiu, Youwen Tian, Weide Ren, Jin Xu, Xiaokun Wang

“…The shape and maximum height of the plastic failure zone was typical trapezoid and 46.12 m, respectively. Finally, the height of the water-conducting fracture zone determined on site was 42–51.8 m. …”
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Analysis of Multifrequency GNSS Signals and an Improved Single-Epoch RTK Method for Medium-Long Baseline by Jian Chen, Jiahui Wang, Kaikun Zhang, Wei Duan, Xingwang Zhao, Chao Liu

“…Furthermore, under the 50 km baseline, the GPS NL ambiguity-fixed rate using the ionosphere-free (IF) combination reaches only 47.74% at the ratio threshold of 2. Finally, compared to the ionosphere-free combination method, the GPS NL ambiguity-fixed rate is increased by 45.52% with the presented method. …”
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E46K α-Synuclein Mutation Fails to Promote Neurite Outgrowth by Not Inducing Cdc42EP2 Expression, Unlike Wild-Type or A53T α-Synuclein in SK-N-SH Cells by Hyunja Jung, Seonghan Kim

“…We also analyzed the differential regulation of cell division control 42 effector protein 2 (Cdc42EP2) using real-time quantitative polymerase chain reaction and western blot analysis. Finally, to confirm the implication of neurite outgrowth, we knocked down Cdc42EP2 using small interfering RNA. …”
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Effects of citizen participation on urban water management based on socioeconomic factors by F. Mardianti, D.E. Purba

“…In fact, other socioeconomic indicators are inversely proportional to what are expected based on theoretical assumption. Finally, educational level and income do not always translate to behavioral changes linked to water pollution management.…”
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A Novel Variant Of Regenerating Iα Gene (REG) In Type II Diabetics Among Pakistani Targeted Population by Sadaf Saleem, Saeeda Baig, Sadia Farrukh, Mazhar Shafiq

“…Results: Blood samples were drawn from 90 finalized patients, including 70 diabetics and 20 controls with an M: F ratio of 12:8. …”
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Cumbre de Sistemas Alimentarios de la ONU 2021: Desmantelando la democracia y restableciendo el control corporativo de los sistemas alimentarios by Matthew Canfield, Molly D Anderson, Philip McMichael

“… Este artículo analiza el desarrollo y la organización de la Cumbre de Sistemas Alimentarios de las Naciones Unidas (UNFSS), que está siendo convocada por el Secretario General de la ONU, António Guterres, a finales de 2021. Aunque pocas personas discutirán que los sistemas alimentarios globales necesitan transformación, ha quedado claro que la Cumbre es, en cambio, un esfuerzo de una poderosa alianza de corporaciones multinacionales, organizaciones filantrópicas y países orientados a la exportación para subvertir las instituciones multilaterales de gobernanza alimentaria y capturar la narrativa global de la “transformación de los sistemas alimentarios”. …”
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Model Construction of InSAR-based Rainfall Thresholds for Landslide Hazards in Yanhe Basin, Chinese Loess Plateau by WANG Zhenliang, CHEN Manyu, ZHAO Jianlin, YUAN Ke, YANG Jie, ZHANG Chen

“…Then the correlations between rainfall factors and landslide shape variables were calculated to determine the rainfall days and effective rainfall attenuation coefficient in the early period. Finally, the effective rainfall (E), rainfall intensity (I) and rainfall duration (D) were calculated, and the E-D, I-D and E-I rainfall threshold models were established by combining the power function. …”
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Eine Systematik diatonischer Skalen by Marc Neufeld

“…The limits of the system’s possibilities are discussed. Finally, the article considers the concept of “new modality” which refers to a connection between scalar and spectral thinking.…”
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Numerical modeling of land subsidence induced by groundwater extraction considering unsaturated effects and using element-free Galerkin (EFG) method by A. Tourei, A. Pak, M. A. Iranmanesh

“…Furthermore, our findings highlight the nonlinear correlation between groundwater extraction and the subsequent decrease in hydraulic head and land subsidence augmentation. Finally, we conducted a parametric study to better understand the effect of various characteristics of aquifers and observe the effect of the aquifer's parameters, such as hydraulic conductivity, elastic modulus, and Poisson's ratio. …”
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Vehicle-Mounted Photovoltaic System Energy Management in Intelligent Transportation Systems: A Maximum Power Point Tracking Control by Jingao Wang, Qifei Liu, Silan Jing

“…Based on this, it does not need to cause multiple interference to the circuit, and the tracking efficiency is high. Finally, the relative experimental results are provided to verify the performance of the proposed method.…”
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Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes by K. V. Ustyantsev, E. V. Berezikov

“…We annotated and characterized the sequence of SL RNA and characterized conserved cis- and SL transsplicing motifs. Finally, we found that a majority of SL trans-spliced genes are evolutionarily conserved and signif icantly over-represented in neoblast-specific genes. …”
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Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation by Wenbo Xu, Shiyan Lv, Xiaoyan Wang, Chengchao Song, Chunyang Xi, Jinglong Yan

“…Furthermore, the supernatant of BMMs after Fer-1 treatment promoted osteogenesis and angiogenesis. Finally, Fer-1 successfully alleviated OP in OVX mice by reducing the level of lipid peroxidation in vivo. …”
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Optimization of land use structure integrating ecosystem service function and economic development—A case study in Dongting Lake Ecological and Economic Zone, China by Yifan Zhu, Min Zhou

“…The modeling results show that the economic benefits of the optimized Dongting Lake Eco-Economic Zone range between [15622.72 × 108,19150.50 × 108] CNY, and the optimized areas of farmland, woodland, grassland, water area, construction land, and unutilized land are[25686.99,25932.61]km2, [22093.37,22295.23]km2,[837.11108,841.41]km2,[7536.86,7767.01]km2,[2660.92,2987.49]km2,[1090.72,1116.36]km2.and the ecosystem service function, pollutant emission level and ecosystem service value of the optimized Dongting Lake Eco-Economic Zone in the optimization scenario, which guarantees higher economic benefits than the status quo scenario, show a better performance than the status quo scenario as a whole. Finally, by spatially allocating the optimization results, the coupled model provides a new perspective and tool for decision-makers to develop sustainable regional land use planning.…”
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Exploring Heat-Response Mechanisms of MicroRNAs Based on Microarray Data of Rice Post-meiosis Panicle by Yan Peng, Xianwen Zhang, Yuewu Liu, Xinbo Chen

“…Then, GO-Slim classification and functional identification of these 178 target genes showed that (1) miRNAs were mainly involved in a series of basic biological processes even under heat conditions; (2) some miRNAs might play important roles in the heat resistance (such as osa-miR164, osa-miR166, osa-miR169, osa-miR319, osa-miR390, osa-miR395, and osa-miR399); (3) osa-miR172 might play important roles in protecting the rice panicle under the heat stress, but osa-miR437, osa-miR418, osa-miR164, miR156, and miR529 might negatively affect rice fertility and panicle flower; and (4) osa-miR414 might inhibit the flowering gene expression by downregulation of LOC_Os 05g51830 to delay the heading of rice. Finally, a heat-induced miRNA-PPI (protein-protein interaction) network was constructed, and three miRNA coregulatory modules were discovered.…”
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Automated Phenotypic Analysis of Mature Soybean Using Multi-View Stereo 3D Reconstruction and Point Cloud Segmentation by Daohan Cui, Pengfei Liu, Yunong Liu, Zhenqing Zhao, Jiang Feng

“…This network enhances feature extraction capabilities through the integration of point cloud and voxel convolution, as well as an orientation-encoding (OE) module. Finally, phenotypic parameters such as stem diameter, pod length, and pod width are extracted and validated against manual measurements. …”
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Freeze-Thaw Cycle Effect on Sputtering Rate of Water-Saturated Yellow Sandstone under Impact Loading by Yunbing Hu, Tianzhu Duan, Penghui Xian, Liang Chen

“…By transforming the fragments into spheres with the corresponding particle sizes, and combining the dissipated energy, the surface specific energy of yellow sandstone with different freeze-thaw temperatures is calculated. Finally, the sputtering rate of the fragments is obtained by using the relationship of total work, dissipated energy, and kinetic energy. …”
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Self-Assembly of Binderless MXene Aerogel for Multiple-Scenario and Responsive Phase Change Composites with Ultrahigh Thermal Energy Storage Density and Exceptional Electromagnetic... by Chuanbiao Zhu, Yurong Hao, Hao Wu, Mengni Chen, Bingqing Quan, Shuang Liu, Xinpeng Hu, Shilong Liu, Qinghong Ji, Xiang Lu, Jinping Qu

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Inserção e atuação do fisioterapeuta residente em um centro obstétrico: relato de experiência by Fernanda Lopes Alves Santos, Débora Sales de Castro

“…No pós parto imediato, muitas parturientes relataram o quanto foi importante ter uma fisioterapeuta nesse momento de suas vidas, fazendo comparações com os partos anteriores ao qual não tiveram esse tipo de assistência. CONSIDERAÇÕES FINAIS: A fisioterapeuta residente teve total autonomia para sugerir condutas às parturientes, associando teoria e prática, resultando em um trabalho de parto efetivo, contribuindo para o qualidade do serviço prestado. …”
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