Electronic media use and sleep in toddlerhood and preschool age by R. Praninskienė, R. Jusienė, I. Laurinaitytė, L. Petronytė, I. Rakickienė, V. Urbonas

“…Children who were sleeping shorter than 8 hours at night were using computers longer during the week and on weekends, they also spent more time on other screens during the weekends. Finally, the longer over all screen time was prominent in the group of children who had the highest scores of sleep problems. …”
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Lipid Metabolism-Related Gene Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Advanced Gastric Cancer by Lijian He, Qiange Ye, Yanmei Zhu, Wenqi Zhong, Guifang Xu, Lei Wang, Zhangding Wang, Xiaoping Zou

“…Furthermore, our results indicated that most chemotherapeutic agents are more effective for AGC patients in the low-risk group than in the high-risk group, and risk scores for AGC are strongly correlated with drug sensitivity. Finally, we performed qRT-PCR experiments to verify the relevant results. …”
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Causal Associations Between Sarcopenia and Gestational Diabetes Mellitus by Huang Y, Zhao S, Hong J, Shen L, Wang Z, Wang D

“…Second, in the reverse MR analysis, we assessed whether GDM influenced sarcopenia-related traits. Finally, sensitivity analysis was conducted to assess the robustness of the MR analysis.Results: Forward MR analysis revealed that appendicular lean mass (odds ratio [OR] = 1.2182, 95% confidence interval [CI]: 1.1397– 1.3021, P < 0.0001), right-hand grip strength (OR= 1.4194, 95% CI: 1.0773– 1.8701, P= 0.0128), left-hand grip strength (OR= 1.6064, 95% CI: 1.2829– 2.0115, P < 0.0001), and usual walking pace (OR= 3.3676, 95% CI: 1.8769– 6.0423, P < 0.0001) were associated with an increased risk of GDM. …”
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Developing a novel model for predicting overall survival in late-onset colon adenocarcinoma patients based on LODDS: a study based on the SEER database and external validation by Chen Chen, Heng-Bo Xia, Wei-Wei Yuan, Meng-Ci Zhou, Xue Zhang, A.-Man Xu

“…The efficacy of the nomograms was assessed by calibration, time-dependent area under the curve (AUC) and decision curve analysis (DCA). Finally, the prognoses of the patients were compared by plotting survival curves on the basis of risk scores. …”
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Intra-specific variation in mortality of even-aged Cryptomeria japonica (L. f.) D. Don. forests can be explained using relationships among long-term stand characteristics by Keiko Fukumoto, Tomohiro Nishizono, Fumiaki Kitahara

“…We then constructed a mortality model using a conventional logistic approach and selected the best model for the stepwise methods. Finally, we applied a piecewise structural equation model (SEM) to identify these variables’ direct and indirect effects. …”
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Adaptation and combination of two scales to measure dispositional gratitude in health sciences faculty: a psychometric analysis by Jesus Alfonso Beltran-Sanchez, José Moral de la Rubia, Adrian Valle de la O, Josue Omar Nava-Manzo, Angeles Dominguez

“…The validation of the one-factor model with convergent reliability and validity suggests that the total scale score serves as an adequate measure of gratitude. Finally, it represents a valuable contribution to the teaching of health sciences since it generates healthy environments with prosocial attitudes that facilitate flourishing in personal and academic life, and in the future, health professionals with humanism as their standard.…”
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The role of SASP in ischemic stroke: a deep dive into cellular mechanisms by Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang

“…Investigated immune infiltration in stroke patients, managed quality control and annotation of single-cell data, cherry-picked central cells based on SASP scores, unearthed essential genes via enrichment analysis, conducted pseudo-time and intercellular communication studies, and prognosticated drugs for hub genes. Finally, authenticated core gene expression in serum of MCAO and Sham rats using real-time fluorescent polymerase chain reaction (RT-qPCR).ResultsFourteen hub genes were discerned. …”
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Self-other distinction modulates the sense of self-agency during joint actions by Laura Zapparoli, Marika Mariano, Lucia Maria Sacheli, Tommaso Berni, Caterina Negrone, Carlo Toneatto, Eraldo Paulesu

“…Do we explicitly and implicitly feel like we are fully in control of the motor act even if the goal is finally achieved by our partner? To address these questions, we measured explicit and implicit sense of self-agency in individual and (coordinated or sequential) interactive contexts. …”
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Development of a Three-Stage Hybrid Model by Utilizing a Two-Stage Signal Decomposition Methodology and Machine Learning Approach to Predict Monthly Runoff at Swat River Basin, Pak... by Muhammad Sibtain, Xianshan Li, Ghulam Nabi, Muhammad Imran Azam, Hassan Bashir

“…Afterward, the SVM algorithm was applied to the decomposed subcomponents for the prediction purpose. Finally, four statistical indices are utilized to measure the performance of the CVS model compared with other hybrid models including CEEMDAN-VMD-MLP (multilayer perceptron), CEEMDAN-SVM, VMD-SVM, CEEMDAN-MLP, VMD-MLP, SVM, and MLP. …”
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CDC25B Is a Prognostic Biomarker Associated With Immune Infiltration and Drug Sensitivity in Hepatocellular Carcinoma by Zixiang Huang, Liangzhi Xu, Zhengqiang Wu, Xiaofeng Xiong, Linfei Luo, Zhili Wen

“…Gene set enrichment analysis (GSEA) was used to identify signaling pathways enriched in CDC25B expression, and differential genes (DEGs) were used to screen out coexpressed hub genes and construct protein-protein interaction (PPI) networks. 5-Ethynyl-2′-deoxyuridine (EDU) staining was used to compare the proliferation and differentiation ability of the HCC cell line (HCC-LM3) after knockdown of CDC25B. Finally, we investigated the mutation of CDC25B in HCC and the relationship between CDC25B expression and tumor cell infiltration of lymphocytes and some immune checkpoints as well as drug sensitivity. …”
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Prevalence and Associated Factors of Perinatal Asphyxia in Neonates Admitted to Ayder Comprehensive Specialized Hospital, Northern Ethiopia: A Cross-Sectional Study by Gebrehiwot Teklehaimanot Gebregziabher, Fikaden Berhe Hadgu, Haftom Temesgen Abebe

“…Variables with P value < 0.25 were fitted to the multivariable binary logistic regression model. Finally, variables with P value < 0.05 were expressed as associated factors of perinatal asphyxia. …”
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ATP Induces Disruption of Tight Junction Proteins via IL-1 Beta-Dependent MMP-9 Activation of Human Blood-Brain Barrier In Vitro by Fuxing Yang, Kai Zhao, Xiufeng Zhang, Jun Zhang, Bainan Xu

“…Degradation of tight junction proteins (TJPs) such as ZO-1 and occludin occurs, which finally contributes to disruption of BBB. A contact coculture system using human astrocytes and hCMEC/D3, an immortalized human brain endothelial cell line, was used to mimic BBB in vitro. …”
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Drawing-Aware Parkinson&#x2019;s Disease Detection Through Hierarchical Deep Learning Models by Ioannis Kansizoglou, Konstantinos A. Tsintotas, Daniel Bratanov, Antonios Gasteratos

“…By directly comparing it against a similar end-to-end classifier, the benefits of our technique are clearly illustrated during experiments. Finally, its performance is compared against several state-of-the-art ML- and DL-based PD detection methods, demonstrating the method&#x2019;s supremacy.…”
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Sustainability by extraction of bioactive compounds from onion seeds by Mestour, Selma, Meniai, Abdeslam-Hassen, Melloul, Sarra, Louaer, Mehdi

“…These fatty acids are well known for their benefits for human health. Finally this research showed ability of the supercritical CO2 extraction to induce a sustainability character while being performing in producing bioactive substances, excluding the use of organic solvent and even replacing classical and traditional techniques like hydrodistillation.…”
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Bioadhesive Chitosan Films Loading Curcumin for Safe and Effective Skin Cancer Topical Treatment by Seila Tolentino, Mylene M. Monteiro, Felipe Saldanha-Araújo, Marcilio Cunha-Filho, Tais Gratieri, Eliete N. Silva Guerra, Guilherme M. Gelfuso

“…Furthermore, curcumin alone was more effective in inhibiting tumor cells than radiotherapy alone (<i>p</i> < 0.01), with no additional benefit observed when curcumin was combined with radiotherapy. Finally, irritation tests confirmed that the films were safe for topical application. …”
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Mechanical properties and piecewise constitutive model of fine sandstone in mining area of western China by Qing Wang, Dongxiao Zhang, Fei Han, Yongqiang Zhao, Pengfei Zhang, Feng Xiong

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Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates by Panagiotis N. Lalagkas, Rachel D. Melamed

“…In this manner, we are able to prioritize a list of drugs based on each predisposing disease, with each drug linked to a set of implicating pathways. Finally, we evaluate our recommendations against drugs currently under investigation for breast cancer. …”
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A study on climate change impacts using lumped versus distributed hydrological models in a semi-arid basin by Farahnaz Baharvand, Ali Reza Massah Bavani, Mohammad Mahdavi, Massoud Goodarzi

“…By analyzing the models, finally, the three best models, including GFDL-CM3, CNRM-CM5 and NorESM1-M models, which reproduce the climatic behavior of monthly temperature and precipitation values, were selected. …”
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Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments by Liu C, Liu W, Lu H, Fan Y, Wang A

“…Subsequently, the key targets were selected to dock with baicalin based on molecular docking. Finally, in vitro experiments were conducted to further validate the predictions.Results: A total of 318 potential targets of baicalin and 752 gout-related targets were screened. …”
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Random-Parameter Multivariate Negative Binomial Regression for Modeling Impacts of Contributing Factors on the Crash Frequency by Crash Types by Chenzhu Wang, Fei Chen, Jianchuan Cheng, Wu Bo, Ping Zhang, Mingyu Hou, Feng Xiao

“…Subsequently, we compute the goodness-of-fit and predictive measures to confirm the superiority of the proposed model. Finally, we also calculate the elasticity effects to augment the comparison. …”
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