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20221
Resource availability and competition shape pollinator trophic specialization in longleaf pine savannas
Published 2025-03-01“…Pollinators were more specialized in communities containing many conspecific pollinators, possibly reflecting pollinator preferences. Finally, in more diverse flowering plant assemblages, pollinators were taxonomic specialists in flower visitation but phylogenetic and functional generalists, providing pollination services across diverse plant assemblages.…”
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20222
Investigating the Prevalence, Antibiotic Resistance Pattern, and Serotyping of Shigella Isolates from Traditional and Industrial Olivier Salads
Published 2025-02-01“…These samples were examined for bacterial isolation and identification, which was finally confirmed by the API-20E kit. Then, a serological reaction was used to confirm Shigella and determine the species. …”
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20223
Advances in Focal Segmental Glomerulosclerosis Treatment From the Perspective of the Newest Mechanisms of Podocyte Injury
Published 2025-02-01“…Corresponding targeted medications such as Abatacept, chemokine receptor (CCR) inhibitors, CDDO-Im (2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide), adenosine monophosphate-activated protein kinase (AMPK) activators, and Adalimumab are currently under investigation. …”
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20224
A core set of risk factors in individuals at risk of rheumatoid arthritis: a systematic literature review informing the EULAR points to consider for conducting clinical trials and...
Published 2021-09-01“…After screening of titles, 138 abstracts were reviewed and 96 articles finally included. Fifty-three articles included data on risk factors including autoantibodies, subclinical inflammation on imaging, clinical features, serum and cellular biomarkers and genetic markers. …”
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20225
Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway
Published 2025-02-01“…Molecular investigations have determined that PHY mitigates the nuclear translocation of nuclear factor kappa B, thereby downregulating myosin light-chain kinase-driven myosin light-chain phosphorylation. …”
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20226
TNF Superfamily: A Growing Saga of Kidney Injury Modulators
Published 2010-01-01“…TWEAK promotes the secretion of MCP-1 and RANTES through NF-kappaB RelA-containing complexes and upregulates CCl21 and CCL19 expression through NF-kappaB inducing kinase (NIK-) dependent RelB/NF-kappaB2 complexes. …”
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20227
Dual-positive gastric cancer: an extremely malignant subtype of gastric cancer with high serum alpha-fetoprotein and carcinoembryonic antigen concentrations
Published 2025-01-01“…Tumor characteristics and overall health conditions were analyzed to identify factors contributing to CEA elevation. Finally, the treatment responses of this group to different treatment modalities were also reviewed.ResultsApproximately 45% of gastric cancer patients with elevated serum AFP also show increased CEA levels, classifying them as the dual-positive gastric cancer (DPGC) subgroup. …”
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20228
An action research study on the needs and perspectives of medical students and junior residents on peer physical examination guidelines to respect medical students’ autonomy and pr...
Published 2025-02-01“…We then conducted interviews of 16 participants and revised our guidelines accordingly. Finally, we asked 632 medical students and 191 junior residents to fill out the form for obtaining informed consent (Questionnaire Survey 2) in order to check the feasibility of our PPE guidelines. …”
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20229
Ex Vivo, In Vitro and In Vivo Bone Health Properties of Grana Padano Cheese
Published 2025-01-01“…As a consequence, metabolized GP digest significantly increased the number of osteoblasts, whereas the metabolized water did not exert this effect. Finally, the mice were fed diets containing GP or CaCO<sub>3</sub> and pea isolate and the in vivo outcomes were assessed through fluorescent probe and computed tomography. …”
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20230
An UPLC-MS/MS Method for Determination of Osimertinib in Rat Plasma: Application to Investigating the Effect of Ginsenoside Rg3 on the Pharmacokinetics of Osimertinib
Published 2020-01-01“…Osimertinib is a novel oral, potent, and irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) for treatment of advanced T790M mutation-positive advanced non-small cell lung cancer, which is commonly combined with ginsenoside Rg3 in clinic to enhance the efficacy and minimize adverse reactions. …”
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20231
Sustained response off treatment after fostamatinib in refractory immune thrombocytopenia: A series of four case reports
Published 2025-12-01“…We present four cases describing treatment with the spleen tyrosine kinase (SYK) inhibitor, fostamatinib, that showed sustained response off treatment (SROT).Case presentations: Case 1 was a 66-year-old male with chronic ITP. …”
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20232
Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3+ T Cell through Modulation of CD11b+ Cell Function
Published 2018-01-01“…In vitro Treg induction was more efficient when CD4+CD25− T cells differentiated in the presence of CD11b+ cells obtained from IL-22Ab-treated GVHD mice, compared with cocultured untreated control cells. Finally, IL-22Ab modulated the expression of cytokines and costimulatory molecules in CD11b+ cells in aGVHD mice. …”
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20233
Prediction model, risk factor score and ventilator-associated pneumonia: A two-stage case-control study
Published 2025-02-01“…We constructed a prediction model by least absolute shrinkage and selection operator (LASSO), random forest (RF), and extreme gradient boosting (XGBoost) models in 363 patients and 363 controls, and weighted RFS was calculated based on significant predictors. Finally, the diagnostic performance of the RFS was testified and further validated in another 177 pairs of VAP case-control study. …”
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20234
Regulation of ofloxacin resistance in Escherichia coli strains causing calf diarrhea by quorum-sensing acyl-homoserine lactone signaling molecules
Published 2025-02-01“…There were 125 differentially expressed genes between bacteria treated with a sub-inhibitory concentration of OFX and those treated with C8, of which 102 were up-regulated and 23 were down. Finally, It found that to adding the C8 significantly increased the resistance of tested bacteria to OFX. …”
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20235
The Most Important Measures in Reducing Infection Control in the Anesthesia Work Environment: An Evidence-Based Study
Published 2024-11-01“…To assess the validity of the approach used in calculating the content validity coefficient (CVR) and the content validity index (CVI), Finally, the Test-Retest method, and Cronbach's alpha coefficient were used to determine reliability. …”
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20236
Investigation of the Protective Effect of Probiotic Lactobacillus plantarum Ep-M17 on the Hepatopancreas of Penaeus vannamei
Published 2024-01-01“…Furthermore, Ep-M17 stimulated gene transcription in crucial immune response-related signalling pathways like the mitogen-activated protein kinase signaling pathway and the antigen processing and presentation pathway. …”
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20237
Identification of key regulators in pancreatic ductal adenocarcinoma using network theoretical approach.
Published 2025-01-01“…Our analysis revealed 33 key regulators were predominantly enriched in neuroactive ligand-receptor interaction, Cell adhesion molecules, Leukocyte transendothelial migration pathways; positive regulation of cell proliferation, positive regulation of protein kinase B signaling biological functions; G-protein beta-subunit binding, receptor binding molecular functions etc. …”
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20238
PENERAPAN KONSEP ARSITEKTUR HIJAU PADA GEDUNG KOMITE OLAHRAGA NASIONAL INDONESIA DIMAKASSAR
Published 2018-06-01“…KONI sebagai suatu organisasi memiliki struktur organisasi yang mengatur berbagai kegiatan olahraga yang ada di Indonesia, selain itu juga KONI bertugas untuk mengembangkan minat dan bakat olahraga yang ada pada masyarakat Indonesia . …”
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20239
Three-Dimensional Digital Documentation for the Conservation of the Prambanan Temple Cluster Using Guided Multi-Sensor Techniques
Published 2025-01-01“…First, APDs were established from the literature to derive the associated multiple detail levels; then, multiple sensors and modes of light detection and ranging (Lidar) scanners and photogrammetry were utilized according to their detail requirements and, finally, point cloud data were processed, integrated, assessed, and validated by the proof of the existence of an APD. …”
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20240
SFDA-MEF: An Unsupervised Spacecraft Feature Deformable Alignment Network for Multi-Exposure Image Fusion
Published 2025-01-01“…We also design a feature point extraction loss function to render our output more conducive to subsequent IOS tasks. Finally, we present a multi-exposure spacecraft image dataset. …”
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