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20141
Triglyceride glucose-waist circumference as a useful predictor for diabetes mellitus: a secondary retrospective analysis utilizing a Japanese cohort study
Published 2025-01-01“…Results After a maximum of 13.0 years of follow-up, 358 people finally developed diabetes. Upon adjusting for covariates, the result showed TyG-WC was positively and independently associated with incident Diabetes Mellitus (DM) (Hazard Ratio (HR): 1.004, 95%C: 1.001–1.006). …”
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20142
The Influence of Vertical Resolution on Internal Tide Energetics and Subsequent Effects on Underwater Acoustic Propagation
Published 2025-01-01“…Increasing the number of isopycnal layers, up to 48, increases the available potential energy contained in high (third‐to‐eighth) tidal baroclinic modes. Finally, sound speed variability and acoustic parameters differ for simulations with less than 48 layers. …”
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20143
Oral Health Impact Profile in Celiac Patients: Analysis of Recent Findings in a Literature Review
Published 2018-01-01“…The first analysis with filters recorded 67 manuscripts accordingly with the selected keywords. Finally, a number of 16 appropriate published papers were comprehended in the review. …”
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20144
Multidrug-Resistant Salmonella enterica Serovar Rissen Clusters Detected in Azores Archipelago, Portugal
Published 2019-01-01“…Considering the well-known spread of MDR between gastrointestinal bacteria, the identification of MDR circulating clones should constitute an alert to public health authorities. Finally, this study constitutes the starting point for the implementation of the “One Health” approach for Salmonella surveillance in Portugal.…”
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20145
Sulfated Cyclocarya paliurus polysaccharides exert immunomodulatory potential on macrophages via Toll-like receptor 4 mediated MAPK/NF-κB signaling pathways
Published 2024-01-01“…Meanwhile, SCP3 could activate mitogen-activated protein kinase (MAPK) and nuclear factor kappa B (NF-κB) signaling pathways, which increased the phosphorylation of Erk1/2, JNK, p38 and NF-κB p65, promoting secretion of cytokines tumor necrosis factor α (TNF-α), interleukin 6 (IL-6) and nitric oxide (NO) as well as the production of reactive oxygen species (ROS). …”
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20146
Structural study, optical properties, thermal stability, and biological activity of a non-centrosymmetric hybrid compound 3,4-Diaminopyridinium perchlorate (3,4-DAPP)
Published 2025-03-01“…Additionally, the optical properties were investigated by UV–Vis absorption and photoluminescence spectroscopy, which exhibit emission property, and a band gap energy of 3.9 eV. Finally, biological activity tests revealed that 3,4-DAPP exhibited moderate antibacterial activity, particularly against Bacillus cereus. …”
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20147
Spatial variation of land use carbon budget and zoning for carbon compensation in the Huai River Eco-economic Belt, China
Published 2025-01-01“…Results indicate that (1) Carbon emissions in the Huai River Eco-economic Belt are generally showing a downward trend, and carbon absorption rises modestly. (2) Carbon emissions exhibit a spatial distribution of higher in the western, northern and eastern regions and lower in the center zone, with large differences in carbon absorption among cities in the same year. (3) Carbon compensation types in the Huai River Eco-economic belt include 7 payment zones, 5 balanced zones and 14 compensated zones, which can be finally classified into 5 categories of carbon compensation space optimization areas by combining with the Normalized Revealed Comparative Advantage Index and model for zoning of carbon compensation. …”
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20148
Multi-Criteria Assessment of Urban Thermal Hotspots: A GIS-Based Remote Sensing Approach in a Mediterranean Climate City
Published 2025-01-01“…Within GIS workflow, the city is divided into LCZs, thermal hotspots are detected, and finally, it is analyzed to understand how urban factors, such as urban boundaries, building density, and vegetation, affect urban scale LST, all using graphical and analytical cross-assessment. …”
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20149
Nomogram model and risk score predicting overall survival and guiding clinical decision in patients with Hodgkin’s lymphoma: an observational study using SEER population-based data...
Published 2022-06-01“…Additionally, the calibration curve and receiver operating characteristic curve were implemented to evaluate the accuracy and discrimination. Finally, we obtained 1-year, 3-year and 5-year survival rates of HL patients.Results 10 912 patients were eligible for the study. …”
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20150
Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients
Published 2025-02-01“…Stability was evaluated using 5-fold cross-validation standard deviation. Finally, 1799 observations with 40 outcome predictors were included. …”
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20151
Furanocoumarin compounds isolated from Dorstenia foetida potentiate irinotecan anticancer activity against colorectal cancer cells
Published 2024-03-01“…., when used individually. Finally, the percentage of apoptotic cells in the HCT116 line treated with the combination was markedly higher than in the cells treated with the individual agent (60 % apoptotic cells for the combination compared to 17 and 45 % for Iri and compound 2 monotherapy, resp). …”
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20152
Immediate Respiratory Warm-Up Effect on Dynamic Inspiratory Muscle Strength in Cardiac Surgery Candidates
Published 2024-11-01“…Results: Covariance analysis showed no significant difference in the average and best values of the S-index, PIF or VC indices at the second tests, between two groups (P>0.05), or in the independent t test and Mann-Whitney U test for the “rate of changes,” between two tests (P>0.05). Finally, intra-group changes, assessed with paired sample t test between two tests, were mostly non-significant for these indices (P>0.05), except for the best VC in the study group (P=0.03). …”
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20153
Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2pos Breast Cancer
Published 2021-01-01“…To explore the possibility of combining targeted drugs with Th1-polarizing vaccines, we undertook a study to examine the impact of combining Th1 cytokines with the relatively broad-spectrum receptor tyrosine kinase antagonist, sunitinib. We found that when a panel of five phenotypically diverse human breast cancer cell lines was subjected to treatment with sunitinib plus recombinant Th1 cytokines IFN-γ and TNF-α, synergistic effects were observed across a number of parameters including different aspects of apoptotic cell death. …”
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20154
lncRNA HHIP-AS1 Promotes the Osteogenic Differentiation Potential and Inhibits the Migration Ability of Periodontal Ligament Stem Cells
Published 2021-01-01“…In addition, the RNA sequencing data showed that 356 mRNAs and 14 lncRNAs were upregulated, including receptor tyrosine kinase-like orphan receptor 2 and nuclear-enriched abundant transcript 1, while 185 mRNAs and 6 lncRNAs were downregulated, including fibroblast growth factor 5 and LINC00973, in HHIP-AS1-depleted PDLSCs. …”
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20155
Electrochemical sensor doped with core-shell structured molecularly imprinted polymer proposed for therapeutic drug monitoring of trazodone hydrochloride
Published 2025-08-01“…Additionally, three different approaches namely; Analytical EcoScale, Analytical GREEnness metric approach and finally, the most recent one; Red-Green-Blue model were applied to evaluate the greenness and whiteness profile of the developed method.…”
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20156
Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2α
Published 2014-01-01“…Moreover, LPS evoked similar levels of phosphorylation of c-Jun N-terminal kinase (JNK) and nuclear factor-κB (NF-κB) in young and middle-aged mice. …”
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20157
Coping Strategies in Migraine without Aura: A Cross-Sectional Study
Published 2019-01-01“…Although migraine patients appeared to be less oriented to transcendent (that means a reduced utilization of an adaptive coping strategy), they did not perceive daily living as more stressful than HCs. Finally, the reduced utilization of the “turning to religion” coping strategy is associated with a great impact of migraine on ability to function on the job or at school, at home, and in social situations in migraine patients.…”
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20158
Proteomic Analysis Reveals the Vital Role of Synaptic Plasticity in the Pathogenesis of Temporal Lobe Epilepsy
Published 2022-01-01“…Bioinformatics analysis indicated 27 DEPs were mainly enriched in “regulation of synaptic plasticity and structure” and “calmodulin-dependent protein kinase activity,” which implicate synaptic remodeling may play a vital role in the pathogenesis of TLE. …”
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20159
An Actor-Oriented and Architecture-Driven Approach for Spatially Explicit Agent-Based Modeling
Published 2023-10-01“…Domain knowledge including spatial specifications is summarized in a class diagram which is later transformed into the agent-based model. Finally, the XML file representing the model produced is used as input in the transformation process leading to code. …”
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20160
Effect of Double Masking with Silk or Cotton Over-masks on the Source Control Capabilities of a Surgical Mask
Published 2022-04-01“…Not only can double masking reduce viral or bacterial transmission, but it can also promote surgical mask longevity, thereby reducing global waste and pollution associated with the use of disposable surgical masks. Finally, an additional study with five human subjects revealed no significant differences in perceived comfort (measured by proxies such as relative humidity, temperature, and CO2 level inside the mask) between single masking and double masking, as well as between double masking with either a silk or cotton over-mask.…”
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