Regulation of Pear Fruit Quality: A Review Based on Chinese Pear Varieties by Ying Zhang, Yudou Cheng, Yuru Ma, Junfeng Guan, Hao Zhang

“…Furthermore, the review offers practical suggestions for improving pear fruit quality and provides insights for researchers in related fields. Finally, future trends in fruit quality research are discussed, offering a forward-looking perspective for advancing the field.…”
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Radiomics-based biomarker for PD-1 status and prognosis analysis in patients with HCC by Gulizaina Hapaer, Feng Che, Qing Xu, Qian Li, Ailin Liang, Zhou Wang, Jituome Ziluo, Xin Zhang, Yi Wei, Yuan Yuan, Bin Song, Bin Song

“…Radiomics score was built for each patient and was integrated with independent clinic radiologic predictors into the radiomics model using multivariable logistic regression analysis.ResultsSeventeen radiomics features were finally selected to construct the radiomics score. …”
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Ultrathin skin-conformable electrodes with high water vapor permeability and stretchability characteristics composed of single-walled carbon nanotube networks assembled on elastome... by Tatsuhiro Horii, Kai Yamashita, Marimo Ito, Kei Okada, Toshinori Fujie

“…., the electrical resistance changes ~1.1 times). Finally, the SWCNT 3rd-SBS nanosheet is applied to detect the surface electromyogram from the forearm of a subject. …”
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A Research Synthesis of Therapeutic Interventions for Whiplash-Associated Disorder (WAD): Part 4 – Noninvasive Interventions for Chronic WAD by Robert W Teasell, J Andrew McClure, David Walton, Jason Pretty, Katherine Salter, Matthew Meyer, Keith Sequeira, Barry Death

“…While the majority of a subset of nine studies supported the effectiveness of interdisciplinary interventions, the two randomized controlled trials provided conflicting results. Finally, there was limited evidence, consisting of one supportive case series each, that both manual joint manipulation and myofeedback training may provide some benefit. …”
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Constructing a new index for measuring industrial estate readiness using the analytic network process (ANP) approach by Siti Afiani Musyarofah, Alva Edy Tontowi, Nur Aini Masruroh, Budhi Sholeh Wibowo

“…IERI measurements were implemented in real cases on Indonesia IEs listed in the National Medium-Term Development Planning (RPJMN) 2020–2024, demonstrating its practical application. Finally, validation was carried out by comparing the results of the IE readiness score using the developed IERI formula and with those of existing tools and plotting based on the IE occupancy rate. …”
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Design of Ice Tolerance Flight Envelope Protection Control System for UAV Based on LSTM Neural Network for Detecting Icing Severity by Ting Yue, Xianlong Wang, Bo Wang, Shang Tai, Hailiang Liu, Lixin Wang, Feihong Jiang

“…This provides a safe range of tracking commands for guiding the aircraft out of the icing region. Finally, the ice tolerance flight envelope protection control law is developed, using a nonlinear dynamic inverse controller (NDIC) as the inner loop and a nonlinear model predictive controller (NMPC) as the outer loop. …”
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Local and Systemic IKKε and NF-κB Signaling Associated with Sjögren’s Syndrome Immunopathogenesis by Weiqian Chen, Jin Lin, Heng Cao, Danyi Xu, Bei Xu, Liqin Xu, Lihuan Yue, Chuanyin Sun, Guolin Wu, Wenbin Qian

“…The inhibitor of κB (IκB) kinase (IKK) family such as IKKα, IKKβ, IKKγ, and IKKε, is required for this signaling. …”
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Regulation of reactive oxygen species and the role of mitochondrial apoptotic-related genes in rheumatoid arthritis by Conghui Gao, Chengqiang Zhang, Lixing Wen, Gailian Zhang, Xiaoping Liu, Jie Wang, Luping Cui, Rui Li, Tingting Nie, Jiaoniu Duan, Yingying Guo

“…Gene Set Enrichment Analysis (GSEA), regulatory network, and drug prediction explored biomarker mechanisms. Finally, key cells analysis included clustering, type annotation, pseudo-temporal study, and interaction, focusing on validated biomarker expression in those cells. …”
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Global sensitivity analysis and uncertainty quantification for a mathematical model of dry anaerobic digestion in plug-flow reactors by Daniele Bernardo Panaro, Andrea Trucchia, Vincenzo Luongo, Maria Rosaria Mattei, Luigi Frunzo

“…The obtained Sobol' indices allowed to perform the quantitative global sensitivity analysis. Finally, the uncertainty quantification results led to the definition of the probability density function related to the investigated quantity of interest. …”
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Exploration of the shared diagnostic genes and molecular mechanism between obesity and atherosclerosis via bioinformatic analysis by Wenrong An, Kegong Tang, Juan Liu, Wenfei Zheng, Guoxia Li, Yunsheng Xu

“…Additionally, higher immune cell infiltration expression was found in both diseases and strongly linked to the diagnostic genes. Finally, we constructed the TF-gene and miRNA-gene networks. …”
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Clinical characteristics and predictive biomarkers of intensive care unit-acquired weakness in patients with cardiogenic shock requiring mechanical circulatory support by Tae Higuchi, Tomomi Ide, Takeo Fujino, Takeshi Tohyama, Yuta Nagatomi, Tomoyuki Nezu, Masataka Ikeda, Toru Hashimoto, Shouji Matsushima, Keisuke Shinohara, Masaaki Nishihara, Takeshi Iyonaga, Tomohiko Akahoshi, Tomoki Ushijima, Akira Shiose, Shintaro Kinugawa, Hiroyuki Tsutsui, Kohtaro Abe

“…The ICU-AW group showed a higher prevalence of extracorporeal membrane oxygenation and ventilator use. Creatine kinase, troponin T, interleukin (IL)-15 levels on admission were significantly higher, whereas hemoglobin and albumin levels were significantly lower in the ICU-AW group. …”
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Vascular Contractility Relies on Integrity of Progranulin Pathway: Insights Into Mitochondrial Function by Shubhnita Singh, Ariane Bruder, Rafael M. Costa, Juliano V. Alves, Sivakama Bharathi, Eric S. Goetzman, Thiago Bruder‐Nascimento

“…In addition, in vivo treatment with mitochondrial fission inhibitor restored mitochondrial quality and vascular contractility, while vascular smooth muscle cells overexpressing PGRN displayed higher lysosome biogenesis, accelerated mitophagy flux, and mitochondrial respiration accompanied by vascular hypercontractility. Finally, angiotensin II failed to induce vascular contractility in PGRN−/−, suggesting a key role of PGRN to maintain the vascular tone. …”
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Propuesta de guía de práctica clínica corta para el manejo de la enfermedad renal crónica by Jorge Félix Rodríguez Ramos, Guillermo Luis Herrera Miranda

“…Se realizó una investigación clínica epidemiológica entre los años 2017-2019, en el Policlínico Luis Augusto Turcios Lima, del municipio de Pinar del Río. La guía fue elaborada siguiendo criterios de la medicina basada en la evidencia, por consenso y por opinión de expertos. …”
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Purification, Characterization and Antibacterial Mechanism of Plantaricin 2-1 by Mengyang LI, Xiaoxue CHE, Qingshen SUN

“…To explore the basic properties and antibacterial mechanism of bacteriocin produced by Lactobacillus plantarum L3, the strain was sub-cultured in MRS medium, and the broth was extracted by ethyl acetate extraction, followed by purification serially through dextran gel chromatography, cation exchange chromatography and reverse phase high performance liquid chromatography (RP-HPLC), and finally identified by liquid chromatography tandem mass spectrometry (LC-MS/MS). …”
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Intraparenchymal Neural Stem/Progenitor Cell Transplantation for Ischemic Stroke Animals: A Meta-Analysis and Systematic Review by Hailong Huang, Kun Qian, Xiaohua Han, Xin Li, Yifeng Zheng, Zhishui Chen, Xiaolin Huang, Hong Chen

“…Among these studies, almost half of the studies claimed no adverse events of tumorigenesis. The finally pooled effect sizes for neurobehavioral and histological assessments were large (1.27 for mNSS, 1.63 for the rotarod test, 0.71 for the cylinder test, and 1.11 for infarct volume reduction). …”
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The effects of tungsten content on the mechanical behavior, ignition and energy-release characteristics of short-tungsten-fibers/Zr-BMGCs under dynamic loading by Xin Yu, Jianbin Li, Xiqiang Gai, Chong Chen, Zhenxiong Wang, Xin Zhao, Hongwei Zhao, Kaichuang Zhang

“…However, analysis of binarized images and quasi-closed chamber overpressure data indicated that the flare area and peak overpressure are reduced at the same impact velocity of 1000 m/s, reflecting a lower energy density per unit mass and reaction efficiency of 435.5 J/g and 4.14 % for SWF/Zr-BMGCs compared to 1592.1 J/g and 15.12 % of Zr-BMGs. …”
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Comprehensive multi-omics analysis showed that CDC6 is a potential prognostic and immunotherapy biomarker for multiple cancer types including HCC by Chenxuan Li, En-di Zhang, Rui Yu, Bo Yuan, Yunxin Yang, Zhong Zeng, Hanfei Huang

“…The role of CDC6 in cancer was analyzed using multiple web platforms and software, including R, cBioPortal, UALCAN, SangerBox and others. Finally, CCK-8, EdU assays and Transwell assays were used to verify the effects of CDC6 knockdown on HCC cell proliferation, migration, and invasion. …”
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<i>Agrobacterium rhizogenes</i>-Mediated Hairy Root Transformation in <i>Rosa</i> by Jun Lu, Yuwen Huang, Yuhan Guo, Chunguo Fan, Guozhen Yuan, Rui Zhou, Jingjing Sun, Mengjuan Bai, Kun Wang, Jinyi Liu, Changquan Wang

“…We established an <i>A. rhizogenes</i>-mediated hairy root transformation system in rose using <i>A. rhizogenes</i> strains MSU440 and Ar Qual, successfully obtained transgenic hairy roots, and conducted preliminary experiments to examine their regeneration by employing the ultraviolet light (UV)-visible reporter eYGFPuv as a marker. Finally, we established a simple hairy root transformation process under non-aseptic conditions. …”
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Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research by Benjamin Punz, Maja Brajnik, Joh Dokler, Jaleesia D. Amos, Litty Johnson, Katie Reilly, Anastasios G. Papadiamantis, Amaia Green Etxabe, Lee Walker, Diego S. T. Martinez, Steffi Friedrichs, Klaus M. Weltring, Nazende Günday-Türeli, Claus Svendsen, Christine Ogilvie Hendren, Mark R. Wiesner, Martin Himly, Iseult Lynch, Thomas E. Exner

“…Application of the InstanceMaps tool (described herein) to research workflows of increasing complexity is presented to demonstrate its utility, starting from (i) documentation of a nanomaterial’s synthesis, functionalisation, and characterisation, over (ii) assessment of a nanomaterial’s transformations in complex media, (iii) description of the culturing of ecotoxicity model organisms Daphnia magna and their use in standardised tests for nanomaterials ecotoxicity assessment, and (iv) visualisation of complex workflows in human immunotoxicity assessment using cell lines and primary cellular models, to (v) the use of the instance map approach for the coordination of materials and data flows in complex multipartner collaborative projects and for the demonstration of case studies. Finally, areas for future development of the instance map approach and the tool are highlighted.…”
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Proton exchange membrane‐based electrocatalytic systems for hydrogen production by Yangyang Zhou, Hongjing Zhong, Shanhu Chen, Guobin Wen, Liang Shen, Yanyong Wang, Ru Chen, Li Tao, Shuangyin Wang

“…., methanol, ethanol, and ammonia) with electrolysis, offering a new opportunity to produce hydrogen using PEM‐based electrocatalytic systems. Finally, several future directions and prospects for developing PEM‐based electrocatalytic systems for H2 production are proposed through devoting more efforts to the key components of devices and reduction of costs.…”
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