Multi-Scale Feature Fusion Model for Bridge Appearance Defect Detection by Rong Pang, Yan Yang, Aiguo Huang, Yan Liu, Peng Zhang, Guangwu Tang

“…Accordingly, a novel Lightweight MFF (namely MFF-L）model for bridge appearance defect detection using a lightweight network EfficientNetV2 and a feature pyramid network is proposed, which fuses multi-scale features to shorten the training speed and improve recognition accuracy. Finally, the effectiveness of the proposed method is evaluated on the bridge disease dataset and public computational fluid dynamic dataset.…”
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Discovery of a non‐nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect by Xiyuan Wang, Zhengsheng Zhan, Zhen Wang, Yan Zhang, Kaiyan Zhao, Han Li, Xiaoqian Zhou, Yuting Guo, Fengying Fan, Jian Ding, Meiyu Geng, Xuekui Yu, Wenhu Duan, Zuoquan Xie

“…Moreover, DW18343 induced immune memory to combat the growth of rechallenged tumors. Finally, DW18343 was shown to be an activator of both the innate and adaptive antitumor immunity in tumor tissue, potentially explaining its strong antitumor effects in vivo. …”
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Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution by Florian Dunker-Seidler, Kathrin Breunig, Magdalena Haubner, Florian Sonntag, Markus Hörer, Rebecca C. Feiner

“…Our data highlight a high vector batch quality with low plasmid-derived and host cell DNA impurities of random origin, critical for mitigating associated safety risks. Finally, we compared nanopore data with orthogonal SMRT sequencing data and observed a higher base quality, but largely similar length and impurity profiles. …”
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Blinder Oaxaca and Wilk Neutrosophic Fuzzy Set-Based IoT Sensor Communication for Remote Healthcare Analysis by Osamah Ibrahim Khalaf, Rajesh Natarajan, Natesh Mahadev, Prasanna Ranjith Christodoss, Thangarasu Nainan, Carlos Andres Tavera Romero, Ghaida Muttashar Abdulsahib

“…With the application of the Blinder Oaxaca function, energy efficiency is enhanced. Finally, the Shapiro Wilk Neutrosophic Fuzzy algorithm is applied for ensuring robust data analysis. …”
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Prognostic significance of ımmunhistochemical axl expression in pancreas ductal adenocarcinomas by Ozden Oz, Asuman Argon, Tulu Ayata Kebat, Ozlem Ozdemir, Savas Yakan

“…Introduction and Aim: Pancreas Ductal Adenocarcinomas (PDACs) are among the leading causes of cancer-related death. Tyrosine kinase receptors (TKRs) are responsible for cell plasticity, chemoresistance, immunosuppression and metastasis potential. …”
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Sensitive Detection of Lasalocid Residue in Chicken by Surface Enhanced Raman Spectroscopy by Yao WANG, Yingying SUN, Yubing JING, Xiyan YANG, Yanfei LI, Jiaxiang HUANG, Xiujin CHEN, Zhaozhou LI, Li CAO, Huaibin KANG

“…Then, by adding HNO3, AuNPs aggregation degree was changed and LAS solubility was increased to further enhance SERS signal. Finally, the method was evaluated by establishing the standard curve and the recovery test of chicken sample. …”
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Accurate prediction for electro-oxidation regeneration of chromium- containing waste acid based on artificial neural network by SHI Yaqi, MENG Guangyuan, CHEN Peng, ZHANG Xinwan, FU Tao, YANG Zhengwu, ZHANG Liansheng, ZHANG Lehua

“…The coefficient of determination(R2) between predicted value and experimental value was greater than 0.97, and the root-mean-square error(RMSE) was less than 0.04. Finally, the average relative error between predicted value and experimental value was 0.14%, which indicated that the model had good generalization ability. …”
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Advanced surgical techniques and considerations in carotid body tumor management: insights from a cohort study by Farooq Ahmad Ganie, Masarat-ul Gani, Hakeem Zubair Ashraf, Shahbaz Bashir, Iqra Nazir Naqash, Mudasir Hamid Bhat, Shadab Maqsood, Altaf Hussain Mir, Mohd Iqbal Dar

“…For Shamblin Type 3 lesions, we employed the RF (Rija-farooq) technique, a retrograde dissection method wherein we first delineated the tumor from the internal carotid artery, followed by the external carotid artery, and finally, at the carotid bifurcation. Results Notably, none of the patients exhibited any postoperative neurological or vascular complications. …”
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Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma by Shibing Zhao, Dasheng Tian, Fei Huang, Lei Wang, Jinhao Cheng, Zhitao He, Qitian Shen, Shuai Liang, Deliang Gong, Jun Liu, Chengfeng Yi, Chun Zhang, Erbao Bian, Juehua Jing, Tao Wang

“…Furthermore, two subgroups of OS patients with distinct prognoses (clusters 1 and 2) were identified. Finally, LMO7-AS1 was chosen for functional experimental validation. …”
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Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release by Shengnan Zhao, Zizhen Gong, Xixi Du, Chunyan Tian, Lingyu Wang, Jiefei Zhou, Congfeng Xu, Yingwei Chen, Wei Cai, Jin Wu

“…Meanwhile, DCA-induced NLRP3 inflammasome activation is at least partially achieved through stimulating extracellular regulated protein kinases (ERK) signaling pathway downstream of S1PR2 followed by promoting of lysosomal cathepsin B release. …”
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Dendrobium chrysotoxum Lindl. Alleviates Diabetic Retinopathy by Preventing Retinal Inflammation and Tight Junction Protein Decrease by Zengyang Yu, Chenyuan Gong, Bin Lu, Li Yang, Yuchen Sheng, Lili Ji, Zhengtao Wang

“…In addition, DC alleviated the increased 1 and phosphorylated p65, IκB, and IκB kinase (IKK) in diabetic rats. DC also reduced the increased serum levels of TNFα, interferon-γ (IFN-γ), IL-6, IL-1β, IL-8, IL-12, IL-2, IL-3, and IL-10 in diabetic rats. …”
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Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cel... by Graciela Ruiz, Heriberto A. Valencia-González, Delia Pérez-Montiel, Felipe Muñoz, Rodolfo Ocadiz-Delgado, Jorge Fernández-Retana, Carlos Pérez-Plasencia, Osbaldo Reséndis-Antonio, Patricio Gariglio, Alejandro García-Carrancá

“…When we performed a meta-analysis using microarray data from cervical cancer biopsies and normal tissues, we found that the expression of OSKM-N and some target genes allowed separating tumor and normal tissues between samples, which enhanced the importance of OSKM-N in the tumorigenesis. Finally, we analyzed and compared both transcript and protein expression profiles of these factors within a cohort of patients with cervical cancer. …”
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A novel imatinib analogue inhibitor of chronic myeloid leukaemia: design, synthesis and characterization—explanation of its folded conformation by Rodolfo Moreno-Fuquen, Juan F. Avellaneda-Tamayo, Kevin Arango-Daraviña, Javier Ellena, Alan R. Kennedy

“…Chronic myeloid leukaemia (CML) is primarily treated using imatinib mesylate, a tyrosine kinase inhibitor (TKI) targeting the BCR::ABL1 oncoprotein. …”
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Optimizing ternary hybrid nanofluids using neural networks, gene expression programming, and multi-objective particle swarm optimization: a computational intelligence strategy by Tao Hai, Ali Basem, As’ad Alizadeh, Pradeep Kumar Singh, Husam Rajab, Chemseddine Maatki, Nidhal Becheikh, Lioua Kolsi, Narinderjit Singh Sawaran Singh, H. Maleki

“…Then, the high-performing models provide the foundation for optimization using the well-established multi-objective particle swarm optimization algorithm. Finally, the decision-making technique TOPSIS is employed to identify the most desirable points from the Pareto front, based on various design scenarios. …”
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Activités artisanales sur la rive droite de la Vesle à Reims/Durocortorum by Émilie Jouhet, Michaël Brunet, Pierre Mathelart, Véronique Matterne

“…The brushes were likely used to remove the down from the sheets of fabric produced, which would have been stretched on a pole, and the fluff subsequently removed by cutting, thereby refining the fabric. Finally, in the absence of vats or tubs, the practice of dyeing in this sector of the city has also been deduced from the high rates of certain plant remains within the carpological samples. …”
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Les fours « à pain » dans les Gaules et les Germanies (ve s. av. J.-C.-ve s. apr. J.-C.), un regard technique by Nicolas Monteix, Camille Noûs

“…The different parts of the ovens are described: the hearth –which also serves as sole–, the –rarely hemispherical– dome, the mouth, the different materials used for construction, the possible base supporting the dome and finally the ancillary fittings (altar, vent, chimney and ashpit). …”
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Caesalpinia sappan L. ethyl acetate extract regulated angiogenesis in atherosclerosis by modulating the miR-126/VEGF signalling pathway by Yue He, Chao Huang, Jingjing Chen, Weizeng Shen

“…Moreover, RT‒PCR assay and Western blot analysis results showed that CSEAE significantly upregulated the expression of miR-126 (p value < 0.01), downregulated the expression of VEGF mRNA (p value < 0.01), and decreased the protein expression levels of VEGF (p value < 0.01), phosphatidyl-inositol-3-kinase (PI3K) (p value < 0.01), and Ser/Thr-protein kinase (AKT1) (p value < 0.01) in mouse aortas, while ELISA showed that CSEAE significantly reduced the serum levels of vascular endothelial growth factor receptor (VEGFR2) (p value < 0.01) and hypoxia-inducible factor-1 (HIF-1) (p value < 0.01) in mice. …”
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Presenting the indigenous model of organizational self-leadership with an emphasis on training in non-governmental organizations by Sajad Ghoreishi, abbas abbaspour, Mostafa Niknami, Morteza Taheri

“…Also, causal conditions with 7 categories, intervening conditions with 9 categories, background conditions with 7 categories, strategies with 9 categories and finally consequences with 5 categories were counted. …”
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An Automatic Approach for the Identification of Offensive Language in Perso-Arabic Urdu Language: Dataset Creation and Evaluation by Salah Ud Din, Shah Khusro, Farman Ali Khan, Munir Ahmad, Oualid Ali, Taher M. Ghazal

“…Secondly, by extracting character-level and word-level features based on bag-of-words, n-grams and TFIDF representation. Finally, an extensive series of experiments were conducted on the extracted features using seven machine learning classifiers to identify the most effective features and classifiers. …”
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Mortal consequences of a cooperative action between Takotsubo syndrome and increased intracranial pressure by Gennaro Alfano, Deasy Ciervo, Teresa Migliore, Antonia Sorbo, Manuela Ariello, Andrea Vitale, Mikko O. Laukkanen, Salvatore Del Gaudio

“…The cardiac diagnostic results were (i) the ECG suggested an elevation in the left ventricular systolic function, (ii) the blood test showed neutrophilia, increased creatine and increased troponin I kinase values, and (iii) the coronary angiogram and ECG analysis demonstrated a lack of a myocardial infarction but identified apical akinesia. …”
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