A rare case of adult-onset vanishing white matter leukoencephalopathy with movement disorder, expressing homozygous EIF2B3 and PRKN pathogenic variants by Bashar Kamal Ali Douden, Yazan Mohammad Abdullah Abufara, Mahmood Fayez Ali Aldrabeeh, Naela Ramadan Mohammad Tell, Ismail Abudaya

“…Nevertheless, the long-term consequences are uncertain due to the illness’s ongoing progression and the absence of a cure currently. …”
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Clinical Holistic Medicine: the “New Medicine”, the Multiparadigmatic Physician, and the Medical Record by Søren Ventegodt, Mohammed Morad, Joav Merrick

“…The excellent physician will choose the right paradigm(s) for the person, the illness, or the situation, and will use the case record to keep track of all the subjective and objective factors and events involved in the process of healing through time. …”
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Attitudes and Barriers to Breastfeeding among Mothers in Princess Nourah Bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia by Razan Yasser Abulreesh, Ibtihaj Abdullah Alqahtani, Zainah Yahya Alshehri, Maha Ali Alsubaie, Shatha Nasser Alburayh, Norah Mohammed Alzamil, Hayat Saleh Alzahrani

“…The participants’ mean age was 34.1 ± 10.4 years; most (87.8%) were Saudi; 92.8% were married; 62% had a bachelor’s degree; and 43% had “enough income.” While 40% of the mothers reported >6 months “exclusive breastfeeding” for the first baby, only 34.8% did so for the last baby, and 54.5% did so for most of all babies altogether. …”
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Predictive Factors for Failure of Noninvasive Ventilation in Adult Intensive Care Unit: A Retrospective Clinical Study by Qimin Chen, Ming Liu, Bo Liu, Wei Li, Daixiu Gao, Lulu Xie, Yu Wu, Liang Li, Ying Liu, Ying Wang, Tang Yan, Yuanyi Liu, Yumei Cheng, Xu Liu, Feng Shen

“…We aim to determine the factors that predict the failure of NIV in critically ill patients with acute respiratory failure (ARF). …”
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Association between biomass cooking fuels and prevalence of tuberculosis among households: a cross-sectional study from 2019 - 2021 in India by Baikunth Kumar Yadav, Pranveer Singh, Prakasini Satapathy, Ponnusamy Thillai Arasu

“…A combined effort of governmental and non-governmental organizations is required to spread awareness about the ill effects of using biomass-based cooking fuels.…”
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Assessment of mental health literacy using a multifaceted measure among a Chinese rural population by Liang Zhou, Shui-yuan Xiao, Mi Hu, Hui-ming Liu, Yu Yu, Zi-wei Liu, Xi-guang Liu, Joyce P Yang

“…Objectives The present study aims to assess mental health literacy (MHL) using a standardised multifaceted 20-item instrument called Mental Health Knowledge Questionnaire (MHKQ) developed by the Chinese Ministry of Health, among a rural Chinese population.Setting Four villages in Liuyang county of Hunan province, China.Participants This was a cross-sectional study. …”
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Adaptive coping mechanisms use and associated factors among adult glaucoma patients attending the University of Gondar Comprehensive Specialized Hospital, Tertiary Eye Care and Tra... by Bisrat Misganaw Geremew, Biruk Fanta Alemayehu, Getenet Shumet Birhan, Biruk Lelisa Eticha, Mahtot Leykun Sisay, Woretaw Endalew Melese, Abebe Tilahun Mekonenne

“…Objective Adaptive coping mechanisms (ACMs) are effective ways to cope with stress and anxiety in patients with chronic illnesses, such as glaucoma. This study aimed to assess the proportion of ACM and associated factors among adult glaucoma patients enrolled at the tertiary eye care and training centre in Northwest Ethiopia.Design An institution-based cross-sectional study.Setting This study was conducted at a tertiary eye care and training centre in Northwest Ethiopia from 15 May 2022 to 30 June 2022.Participants The study included a sample of 398 adult glaucoma patients selected using a systematic random sampling technique.Primary and secondary outcome measures The participants were diagnosed with glaucoma by ophthalmologists. …”
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Role of laparoscopic surgery in blunt abdominal trauma; retrospective analysis in a tertiary trauma center by Rifan Alyami, Ahad E. Alotaibi, Leen Almohayya, Ajyad Al Jawad, Raghad Almukhayzim, Abeer Alhoumedan, Rakan S. Aldusari

“…Conclusion While laparoscopic techniques have been used for decades in abdominal surgeries, a consensus on their effectiveness and accuracy in diagnosing blunt abdominal injuries in trauma settings is still lacking. …”
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Understanding human papillomavirus vaccine response and efficacy in people living with HIV: A systematic mixed studies review and meta-analysis. by Alvine M Akumbom, Alanna J Bergman, Howard Strickler, Chakra Budhathoki, Manka Nkimbeng, Raeven Grant, Nancy R Reynolds, Kawsar R Talaat

“…The mean difference in GMT for HPV18 between PWH and PWoH was -536.23 (95% CI: -830.66, -241.81); approximately 22 times higher than HPV18 seropositivity cut-offs, assuming milli-Merck Units per milliliter. Risk factors for incident or persistent infections in PWH included: failure to seroconvert after vaccination, baseline CD4+ T-cell count <500 cells/mm3, early age of sexual debut, HIV viral load ≥ 400 copies/mL. …”
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Comparison of CRP, Procalcitonin, Neutrophil Counts, Eosinophil Counts, sTREM-1, and OPN between Pneumonic and Nonpneumonic Exacerbations in COPD Patients by Shan Mou, Wei Zhang, Yan Deng, Zhijun Tang, Depeng Jiang

“…The patients with community-acquired pneumonia (CAP) and acute exacerbations of COPD (AECOPD) could have a higher risk of acute and severe respiratory illness than those without CAP in AECOPD. Consequently, early identification of pneumonia in AECOPD is quite important. …”
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The clinical profile and outcome of patients receiving continuation electroconvulsive therapy (C-ECT): A retrospective study by Sandeep Grover, Sanjana Kathiravan, Subho Chakrabarti

“…Results: A total of 72 C-ECT courses were identified that were used in 60 patients. Out of all the patients receiving ECT, only 3.25% of patients receive C-ECT. …”
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Burden of Respiratory Disease in Pediatric Intensive Care Unit: Experience from a PICU of a Tertiary Care Center in Pakistan by Sidra Ishaque, Nazia Bibi, Zaiba Shafik Dawood, Janeeta Hamid, Quratulain Maha, Syeda Asma Sherazi, Ali Faisal Saleem, Qalab Abbas, Naveed Ur Rehman Siddiqui, Anwar Ul Haque

“…A retrospective study was conducted on children aged 1 month to 18 years who were diagnosed with respiratory illness at the PICU in a tertiary hospital in Karachi, Pakistan. …”
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Myxedema Psychosis: Neuropsychiatric Manifestations and Rhabdomyolysis Unmasking Hypothyroidism by Sundus Sardar, Mhd-Baraa Habib, Aseel Sukik, Bashar Tanous, Sara Mohamed, Raad Tahtouh, Abdelrahman Hamad, Mouhand F. H. Mohamed

“…She had no prior history of psychiatric illnesses. She underwent total thyroidectomy three years before the current presentation due to papillary thyroid cancer. …”
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A scoping review on peer-led interventions to improve youth mental health in low- and middle-income countries by Dana Chow, Dunstan J. Matungwa, Elizabeth R. Blackwood, Paul Pronyk, Dorothy Dow

“…Youth living in low- and middle-income countries (LMICs) have an increased vulnerability to mental illnesses, with many lacking access to adequate treatment. …”
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The performance of a lateral flow SARS-CoV-2 antibody assay and semi-autonomous SARS-CoV-2 antisense and sense RNA fluorescence in situ hybridization assay in a prospective cohort... by Inge D Wijnberg, Anton J Soons, Johan G Reimerink, Marit Wiersma, Marie Christine J Plat, Tom van Gool, Gijsbert J Jansen, Cornelis Stijnis, Jack G Koning, Adam Meijer

“…At the beginning of the COVID-19 pandemic, diagnostic testing was not accessible for mildly ill or asymptomatic individuals. Military operational circumstances exclude the usage of reference laboratory tests. …”
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Assessing the effects of therapeutic combinations on SARS-CoV-2 infected patient outcomes: A big data approach. by Hamidreza Moradi, H Timothy Bunnell, Bradley S Price, Maryam Khodaverdi, Michael T Vest, James Z Porterfield, Alfred J Anzalone, Susan L Santangelo, Wesley Kimble, Jeremy Harper, William B Hillegass, Sally L Hodder, National COVID Cohort Collaborative (N3C) Consortium

“…<h4>Background</h4>The COVID-19 pandemic has demonstrated the need for efficient and comprehensive, simultaneous assessment of multiple combined novel therapies for viral infection across the range of illness severity. Randomized Controlled Trials (RCT) are the gold standard by which efficacy of therapeutic agents is demonstrated. …”
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Intestinal obstruction caused by disseminated mycobacterium avium complex disease following solid organ transplantation: a case report by Akane Mita, Sho Nakakubo, Yusuke Nishimura, Hideki Shima, Masaaki Watanabe, Tsuyoshi Shimamura, Satoshi Konno

“…However, biopsies showed CD68-positive histiocyte-like cells with numerous acid-fast bacilli, confirming disseminated MAC infection. …”
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Barriers and facilitators to the conduct of critical care research in low and lower-middle income countries: A scoping review. by Bharath Kumar Tirupakuzhi Vijayaraghavan, Ena Gupta, Nagarajan Ramakrishnan, Abi Beane, Rashan Haniffa, Nazir Lone, Nicolette de Keizer, Neill K J Adhikari

“…Two reviewers independently reviewed titles and abstracts, and where necessary, the full-text to select eligible studies. …”
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Association of TyG index with mortality at 28 days in sepsis patients in intensive care from MIMIC IV database by Heping Xu, Jinyuan Xie, Yan Xia, Huan Niu, Hong Wang, Feng Zhan

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Influenza vaccination of school teachers: A scoping review and an impact estimation. by Anne Huiberts, Brigitte van Cleef, Aimée Tjon-A-Tsien, Frederika Dijkstra, Imke Schreuder, Ewout Fanoy, Arianne van Gageldonk, Wim van der Hoek, Liselotte van Asten

“…<h4>Introduction</h4>Influenza vaccination, besides protecting traditional risk groups, can protect employees and reduce illness-related absence, which is especially relevant in sectors with staff shortages. …”
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