Enhancing the utility of polygenic scores in Alzheimer’s disease through systematic curation and annotation by Savannah Mwesigwa, Yulin Dai, Nitesh Enduru, Zhongming Zhao, Zhongming Zhao

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Fabrication of Dye-Sensitized Solar Cells (DSSC) Using Mg-Doped ZnO as Photoanode and Extract of Rose Myrtle (Rhodomyrtus tomentosa) as Natural Dye by Nurdin Siregar, Motlan, Jonny Haratua Panggabean, Makmur Sirait, Juniastel Rajagukguk, Noto Susanto Gultom, Fedlu Kedir Sabir

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Perspective of Need for First Aid Education in Bulgarian Schools by Daniela Baleva

“…Results: Approximately 59% of respondents state their willingness to undergo further first aid and disaster response training. …”
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Severe Hypoglycemia due to Isolated ACTH Deficiency in Children: A New Case Report and Review of the Literature by Michael Y. Torchinsky, Robert Wineman, George W. Moll

“…Review of the literature showed that the prevalence of this condition could be underestimated in the neonatal period and in Prader-Willi syndrome. Isolated ACTH deficiency occurs in older children as well as in neonates.…”
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Purging the Past and Gauging the Future: Stage Puritans as Manifestations of Religious Trauma in Restoration Comedies Adapted from European Sources (1660-1689) by Alice Marion-Ferrand

“…This paper focuses on five Restoration comedies with religious concerns composed between Charles II’s return to England and the Glorious Revolution, and adapted from French, Spanish and English (Elizabethan and Jacobean) sources: The Law Against Lovers (1663) by William Davenant, Tartuffe or the French Puritan (1670) by Matthew Medbourne, Sir Patient Fancy (1678) by Aphra Behn, The Spanish Fryar, or the Double-Discovery (1681) by John Dryden, and Sir Courtly Nice, or It Cannot Be (1685) by John Crowne. …”
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Modeling the Traveler’s Route Choice Behavior under Unexpected Accidents by Minqing Zhu, Peng Shi, Hongjun Cui, Xinye Li, Xinwei Ma

“…The study finds that with the increase in congestion level, travelers are more willing to change the route; during the commute, travelers tend to choose the route with less travel time and angular cost; in the moderate and serious congestion scenarios, travelers no longer reject the detour route; attribute perception difference, scale effect, and psychological threshold effect; affect travelers’ route choice behavior. …”
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When plastisphere and drilosphere meet: Earthworms facilitate microbiome and nutrient turnover to accelerate biodegradation of agricultural plastic films by Caide Huang, Liuwei Wang, Wei-Min Wu, Yvan Capowiez, Yuhui Qiao, Deyi Hou

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Design and implementation of a model for OS kernel integrity protection by Dong-hai TIAN, Jun-hua CHEN, Xiao-qi JIA, Chang-zhen HU

“…Untrusted kernel extensions were considered to be a big threat to OS kernel integrity because once they were loaded into the kernel space,then they may corrupt both the OS kernel data and code at will.To address this problem,MAC-based model named MOKIP for OS kernel integrity protection was presented.The basic idea of MOKIP was to set different integrity labels for different entities in the kernel space,and then ensure that the entities with low integrity label cannot harm the entities with high integrity label.A prototype system based on the hardware assisted virtualization technology was implemented.The experimental results show that proposed system is effective at defending against various malicious kernel extension attacks within a little performance overhead which is less than 13%.…”
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‘Wisdom is a gift given to the Wise’: Florence Farr (1860–1917): New Woman, Actress and Pagan Priestess by Muriel Pécastaing-Boissière

“…Nevertheless, Farr has long been studied almost exclusively as George Bernard Shaw’s or William Butler Yeats’s so-called ‘Muse’. Admittedly, Shaw and Yeats wrote leading parts for her, but it was she who commissioned and staged some of their very first plays. …”
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EVALUATION OF GRADUATES OF RESIDENCY IN DIGESTIVE SURGERY AND COLOPROCTOLOGY IN A SINGLE CENTER: A 43 YEARS PORTRAIT by Gilton Marques FONSECA, Luiz Henrique DA COSTA, José Donizeti MEIRA JUNIOR, Nelson Fausto DELL’AQUILLA JUNIOR, Ulysses RIBEIRO JUNIOR, Paulo HERMAN, Luiz Augusto Carneiro D’ALBUQUERQUE

“…The training significantly impacted all respondents’ professional lives, with 92.5% willing to choose the same specialty again. Graduates from Era 2 showed a higher proportion of females, residents of cities other than São Paulo, and graduates from institutions outside FMUSP. …”
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The American Society of Pain and Neuroscience (ASPN) Guidelines and Consensus on the Definition, Current Evidence, Clinical Use and Future Applications for Physiologic Closed-Loop... by Pope JE, Deer TR, Sayed D, Antony AB, Bhandal HS, Calodney AK, Chakravarthy K, Costandi S, Diep J, Durbhakula S, Fishman MA, Gilligan C, Goree JH, Guirguis M, Hagedorn JM, Hunter CW, Kallewaard JW, Kapural L, Lam CM, Li S, Mayrsohn B, Nijhuis H, Nikolic S, Petersen EA, Poree LR, Puri SK, Reece DE, Rosen SM, Russo MA, Shah JM, Staats PS, Verrills P, Vu CM, Levy RM, Mekhail N

“…Jason E Pope,1 Timothy Ray Deer,2 Dawood Sayed,3 Ajay B Antony,4 Harjot Singh Bhandal,1 Aaron K Calodney,5 Krishnan Chakravarthy,6 Shrif Costandi,7 Jack Diep,8 Shravani Durbhakula,9 Michael A Fishman,10 Christopher Gilligan,11 Johnathan Heck Goree,12 Maged Guirguis,13 Jonathan Michael Hagedorn,14 Corey William Hunter,15,16 Jan Willem Kallewaard,17,18 Leonardo Kapural,19– 21 Christopher M Lam,3 Sean Li,22 Brian Mayrsohn,23,24 Harold Nijhuis,25 Serge Nikolic,26 Erika A Petersen,27 Lawrence Raymond Poree,28 Shawn K Puri,29 David E Reece,30 Steven Mark Rosen,31 Marc A Russo,32 Jay M Shah,33 Peter Sean Staats,34 Paul Verrills,35 Chau M Vu,1 Robert M Levy,36 Nagy Mekhail37 1Evolve Restorative Center, Santa Rosa, CA, USA; 2Pain Services, The Spine & Nerve Center of the Virginias, Charleston, WV, USA; 3Department of Anesthesiology and Pain Medicine, The University of Kansas Medical Center, Kansas City, KS, USA; 4The Orthopaedic Institute, Gainesville, FL, USA; 5Clinical Research, Precision Spine Care, Tyler, TX, USA; 6Anesthesiology and Pain Medicine, Solaris Research Institute, Wilmington, DE, USA; 7Pain Medicine, Cleveland Clinic, Cleveland, OH, USA; 8Nevada Pain Management, Las Vegas, NV, USA; 9Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA; 10Michael Fishman MD PLLC, Lebanon, PA, USA; 11Robert Wood Johnson University Hospital, New Brunswick, NJ, USA; 12Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 13Interventional Pain Management Department, Ochsner Health System, New Orleans, LA, USA; 14Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA; 15Ainsworth Institute of Pain Management, New York City, NY, USA; 16Physical Medicine & Rehabilitation, Icahn School of Medicine at Mount Sinai Hospital, New York City, NY, USA; 17Amsterdam University Medical Centre, Amsterdam, The Netherlands; 18Rijnstate Hospital, Arnhem, The Netherlands; 19Carolinas Pain Institute, Winston Salem, NC, USA; 20Centers for Clinical Research, Winston Salem, NC, USA; 21Chronic Pain Research Institute, Winston Salem, NC, USA; 22National Spine and Pain Centers, Shrewsbury, NJ, USA; 23Interventional Pain Management, Maywell Health, Plainview, NY, USA; 24Interventional Pain Management, Maywell Health, New York City, NY, USA; 25Anesthesiology, St Antonius Hospital, Nieuwegein, Utrecht, The Netherlands; 26Pain Medicine and Neuromodulation, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK; 27Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 28Anesthesia- Division of Pain Medicine, University of California, San Francisco, CA, USA; 29Integrated Pain Associates, Killeen, TX, USA; 30Absolute Pain Management, Rockville, MD, USA; 31Delaware Valley Pain and Spine Institute, Trevose, PA, USA; 32School of Biomedical Sciences, University of Newcastle, Newcastle, NSW, Australia; 33Samwell Institute of Pain Management, Colonia, Livingston, and Englewood, NJ, USA; 34National Spine and Pain Centers, Atlantic Beach, FL, USA; 35Metropain, Melbourne, VIC, Australia; 36Neuromodulation: Technology at the Neural Interface, International Neuromodulation Society, Boca Raton, FL, USA; 37Evidence-Based Pain Management Research, Cleveland Clinic, Cleveland, OH, USACorrespondence: Timothy Ray Deer, The Spine and Nerve Center of the Virginias, 400 Court Street, Charleston, WV, 25304, USA, Tel +1 304 347 6141, Email doctdeer@aol.comIntroduction: Neuromodulation has been a staple of treatment for moderate-to-severe chronic refractory pain since the introduction of the first spinal cord stimulator by Norman Shealy in 1967. …”
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New version of derivative consequence argument and response to objections by B. V. Faul

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Do health professionals know about overdiagnosis in screening, and how are they dealing with it? A mixed-methods systematic scoping review. by Veerle Piessens, Ann Van den Bruel, An Piessens, Ann Van Hecke, John Brandt Brodersen, Emelien Lauwerier, Florian Stul, An De Sutter, Stefan Heytens

“…This seems intertwined with their overall beliefs about the benefits of screening, their position towards offering screening, and their willingness to inform screening candidates about overdiagnosis. …”
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Das Menschliche in der Musik . August Halms prozessuale Metaphorik im Brennpunkt analysetheoretischer Fragestellungen by Astrid Bolay

“…Bei einer meta-sprachlichen Analyse seiner Formulierungen nach Lakoff und Johnson wird sichtbar, dass menschliche, letztlich körperbasierte metaphorische Konzepte sein (und unser) gesamtes, räumliches wie prozessuales ‒ und zum großen Teil unbewusstes ‒ Verständnis von Musik durchdringen; eine Perspektive, die jede Grenzziehung innerhalb dieses Spektrums von Metaphorizität willkürlich erscheinen lässt. Wenn anschließend einige der ›energetischen‹ Konzeptualisierungen, die für Halms Verständnis von Musik besonders typisch sind, daraufhin untersucht werden, wie sie kognitivistisch funktionieren und was sie leisten, so geschieht das auch mit dem Ziel, ihr Potenzial für die seriöse Musikanalyse unserer Tage nutzbar zu machen. …”
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Stereotypes and social representations associated with pediatric surgeons among medical students, residents and physicians: a cross-sectional study by Coline Ducrot, Max Piffoux, Mathilde Payen, Sebastien Raux, Franck Rolland, Evan Gouy, Linh Nam Truong, Ariel Frajerman, Florent Vinchon, Nawale Hadouiri

“…Unexpectedly, attending to courses on pediatric surgery was not associated with willingness to become a PS. Conclusions The SR of pediatric surgery is rather neutral although only a minority of responders consider practicing pediatric surgery. …”
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Intravenous Ketamine for Suicidal Behavior in Severe Depression with Psychotic Features by T. V. Pavan Kumar, Divya Bolla, Raj Kiran Donthu, Anzory Pathak

“…As the patient and family members were not willing for mECT, based on evidence, IV ketamine was discussed and started. …”
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THE TRANSFORMATION PERIODS IN THE RUSSIAN-TURKISH RELATIONS (1991-2016) by D. G. Bdoyan

“…Further development of the relations resulted in willingness of the two countries to transition from a multidimensional to a strategic partnership. …”
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Positive Solutions to Periodic Boundary Value Problems of Nonlinear Fractional Differential Equations at Resonance by Lei Hu

“…By Leggett-Williams norm-type theorem for coincidences due to O’Regan and Zima, we discuss the existence of positive solutions to fractional order with periodic boundary conditions at resonance. …”
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Systemic Lupus Erythematosus (SLE) with Acute Nephritis, Antineutrophil Cytoplasmic Antibody- (ANCA-) Associated Vasculitis, and Thrombotic Thrombocytopenic Purpura (TTP): A Rare C... by Sohail Farshad, Christopher Kanaan, Solomiia Savedchuk, Dillon S. Karmo, Alexandra Halalau, Abhishek Swami

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Aleksandr Bogdanov and Sergei Eisenstein on Emotions: The Affectional, the Theory of Expressiveness, and the Emotional Script by Bugaeva Lyubov

“…In Empiriomonism, Aleksandr Bogdanov introduces the term ‘affectional’ that he borrowed from Richard Avenarius but revised in the light of William James’s theory of emotions. The ‘affectional’ is an index of energy balance between suffering and pleasure. …”
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