Candidate SNP-markers altering TBP binding affinity for promoters of the Y-linked genes CDY2A, SHOX, and ZFY are lowering many indexes of reproductive potential in men by M. P. Ponomarenko, E. B. Sharypova, I. A. Drachkova, L. K. Savinkova, I. V. Chadaeva, D. A. Rasskazov, P. M. Ponomarenko, L. V. Osadchuk, A. V. Osadchuk

“…., SHOX: rs28378830). This indicates a wide range of MRI indicators, alterations in which should be expected in the case of SNPs in the promoters of the human Y-chromosome genes and which can go far beyond changes in male fertility.…”
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Effects of core stability exercises on balance ability of children and adolescents with intellectual disabilities: A systematic review and meta-analysis. by Junjie Zhou, Yecheng Zhong, Wenhong Xu

“…Although pooled analyses also highlighted improvements in static and static-dynamic balance with large effect sizes over active control groups, the results were not statistically significant and should be interpreted with caution given the wide confidence intervals. The heterogeneity among the identified studies and the limited number of eligible studies may reduce the reliability of the results, but these findings emphasise the need for additional research in this domain.…”
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Implementation of rural provider-to-provider telehealth in country Western Australia: a retrospective observational analysis via the RE-AIM framework by Kaylie Toll, Suzanne Robinson, Stephen Andrew, Aled Williams, Justin Yeung, Richard Varhol, Joanna C. Moullin

“…Conclusion There is a steady expansion in the availability of provider-to-provider clinical telehealth services delivered by the WACHS Command Centre across country WA, but with wide variability of usage depending on region, site, and health facility type. …”
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Magnetic resonance imaging in primates. The example of the mouse lemur (Microcebus murinus): From detection of pathological aging to therapeutic evaluations by Nelly Joseph-Mathurin, Olene Dorieux, Audrey Kraska, Anne Bertrand, Mathieu Santin, Nadine El Tannir El Tayara, Marc Dhenain

“…Rodents and particularly transgenic mice are widely used as models for research on physiopathology of cerebral aging, neurodegenerative diseases and for the evaluation of therapies. …”
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Characterization and in vitro anticancer study of PEGylated liposome dually loaded with ferulic acid and doxorubicin by Andang Miatmoko, Patricia Kinanti Christy, Alfionita Isnaini, Berlian Sarasitha Hariawan, Devy Maulidya Cahyani, Margaret Ahmad, Nuzul Wahyuning Diyah, Mohamad Faris Adrianto, Ravi Kiran Deevi, Iwan Sahrial Hamid, Juni Ekowati

“…Abstract Doxorubicin is an anthracycline antibiotic widely used in cancer therapy. However, its cytotoxic properties affect both cancerous and healthy cells. …”
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Analysis of the CHS Gene Family Reveals Its Functional Responses to Hormones, Salinity, and Drought Stress in Moso Bamboo (<i>Phyllostachys edulis</i>) by Shiying Su, Xueyun Xuan, Jiaqi Tan, Zhen Yu, Yang Jiao, Zhijun Zhang, Muthusamy Ramakrishnan

“…However, its molecular functions remain largely unknown in <i>Phyllostachys edulis</i>, which is one of the most economically and ecologically important bamboo species and the most widely distributed one in China. This study identified 17 <i>CHS</i> genes in <i>Phyllostachys edulis</i> and classified them into seven subgroups, showing a closer evolutionary relationship to <i>CHS</i> genes from rice. …”
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Vegetative Propagation of Perennial Cut Flower Flax (Linum spp.) in a Controlled Environment by Elizabeth A. Goodman, Neil O. Anderson

“…Perennial flax (Linum austriacum, Linum perenne, L. austriacum) has a wide range of uses for the horticultural and agronomic markets. …”
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Dietary supplementation with Epimedium contributes to the improvement of hormone levels, gut microbiota, and serum metabolite composition in the Chinese forest musk deer (Moschus b... by Shan Xie, Shan Xie, Qinlin Yang, Zaixiang Ying, Zaixiang Ying, Mingcheng Cai, Wenqiao Fan, Hanyu Gao, Hanyu Gao, Xiaolan Feng, Yongjiang Wu

“…The results indicated that the inclusion of Epimedium in the diet increased dry matter intake (DMI) and improved the ratio of feed to gain (F/G), with an increase in fecal testosterone levels (p &lt; 0.05). 16S rDNA sequencing analysis revealed that Epimedium enhanced the richness and diversity of the gut microbiota in the Chinese forest musk deer, increasing the relative abundance of beneficial bacteria such as Firmicutes, while reducing the relative abundance of the potentially pathogenic Proteobacteria (p &lt; 0.05). A widely targeted metabolomics analysis identified 25 differential metabolites between the two groups. …”
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Metformin Use and Survival in Patients with Advanced Extrahepatic Cholangiocarcinoma: A Single-Center Cohort Study in Fuyang, China by Jinqing Wu, Yabo Zhou, Guizhou Wang

“…Metformin is an oral antidiabetic agent that has been widely prescribed for the treatment of type II diabetes. …”
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mHealth knowledge and usage in maternal healthcare delivery: perspectives and experiences of healthcare practitioners in Ghana by Edward Kwabena Ameyaw, Padmore Adusei Amoah, Pascal Agbadi, Aikins Amoako Asiama

“…In each of these regions, one urban and one rural setting were selected to ascertain pertinent data from a wide range of maternity health practitioners and directors of health services operating within these regions.Participants Purposive sampling technique was used to recruit 32 participants, who fall into two primary groups: directors of health services (n=9) and maternity health practitioners (23).Results The findings revealed that maternal healthcare providers were familiar with and frequently used mHealth technologies (typically video calls/conferences and text messages). mHealth was considered a useful tool in maternal healthcare as it enhanced the efficiency of service delivery and improved practitioners’ performance. mHealth facilities eased access to digital medical information, user-friendly interfaces and the ability to facilitate remote consultations. …”
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Economic impact of medication non-adherence by disease groups: a systematic review by Victoria Garcia-Cardenas, Rachelle Louise Cutler, Fernando Fernandez-Llimos, Michael Frommer, Charlie Benrimoj

“…Relevant information was extracted and quality assessed using the Drummond checklist.Results Seventy-nine individual studies assessing the cost of medication non-adherence across 14 disease groups were included. Wide-scoping cost variations were reported, with lower levels of adherence generally associated with higher total costs. …”
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Natural Language Processing and Social Determinants of Health in Mental Health Research: AI-Assisted Scoping Review by Dmitry A Scherbakov, Nina C Hubig, Leslie A Lenert, Alexander V Alekseyenko, Jihad S Obeid

“… Abstract BackgroundThe use of natural language processing (NLP) in mental health research is increasing, with a wide range of applications and datasets being investigated. …”
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A retrospective analysis of migraine prophylaxis with anti-CGRP monoclonal antibodies at the hospital of Lithuanian University of Health Sciences Kaunas Clinics by V. Karpavičiūtė, K. Statkevičienė, G. Žemgulytė

“…Preventive treatment of anti-calcitonin gene-related peptide monoclonal antibodies (anti-CGRP mAbs) is currently being widely investigated worldwide. Materials and methods. …”
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Identification of mesenchymal stem cell populations with high osteogenic potential using difference in cell division rate by Maya Watanabe, Yukiyo Asawa, Dan Riu, Tomoaki Sakamoto, Kazuto Hoshi, Atsuhiko Hikita

“…Introduction: In bone regenerative medicine, mesenchymal stem cells (MSCs) have been widely investigated for their potential in bone regeneration. …”
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Occurrence and bioaccumulation of organophosphate flame retardants in high-altitude regions: A comprehensive field survey in Qinghai Province, China by Haibao Zhu, Jinlin Hu, Zheng Ruan, Danhua Liu, Meirong Zhao

“…Organophosphate flame retardants (OPFRs) are a class of substances that pose potential risks to human health and ecosystems due to their large-scale production, wide range of applications, and ubiquitous presence in the environment. …”
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The Role of Establishing a Multidisciplinary Team for Idiopathic Granulomatous Mastitis in Improving Patient Outcomes and Spreading Awareness about Recent Disease Trends by Rami J. Yaghan, Nehad M. Ayoub, Shadi Hamouri, Alia Al-Mohtaseb, Maha Gharaibeh, Lamees Yaghan, Mahmoud Al-Dari, Hiba Al-Kaff, Nabil A. Al-Zoubi

“…Suspicion for malignancy was raised in one out of 39 ultrasound reports, and one out of 20 mammography reports. Wide local excision was the main treatment modality (95.5%). 19 patients (43.2%) received corticosteroids. …”
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Like milk on the stove: Healthcare professionals navigating uncertainty when caring for families with 22q11DS. by Sophie Ayoub, Eva De Clercq, Cheryl Cytrynbaum, Luzius A Steiner, Bernice S Elger

“…Clinical manifestations vary widely among individuals and across different life stages. …”
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Identification of ALEKSIN as a novel multi-IRF inhibitor of IRF- and STAT-mediated transcription in vascular inflammation and atherosclerosis by Aleksandra Antonczyk, Katarzyna Kluzek, Natalia Herbich, Mahdi Eskandarian Boroujeni, Bart Krist, Dorota Wronka, Anna Karlik, Lukasz Przybyl, Adam Plewinski, Joanna Wesoly, Hans A. R. Bluyssen

“…This was in line with the common inhibition of ALEKSIN and STATTIC observed on the genome-wide expression of pro-inflammatory IRF/STAT/NF-κB target genes, as well as on the migration of HMECs. …”
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Validation of the Food Safe Zone questionnaire for families of individuals with Prader-Willi syndrome by Elisabeth M. Dykens, Elizabeth Roof, Hailee Hunt-Hawkins, Theresa V. Strong

“…., locking food sources, constant supervision around food, alerting others). Although widely used, these strategies have yet to be systematically examined. …”
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Lagorio’s Wall in the Crimea: pages of scientific activity of the geologist Oleksandr Lagorio by Dmytro Mikhalenok

“…The formation of the Lagorio’s scientific views in the universities of Dörpt (now Tartu, Estonia) and Warsaw (now Poland) are shown. In the latter, a wide profiled scientific school of the scientist was formed, including synthetic geology (experimental mineralogy and petrography)—the most well-known representative of which was the Polish scientist Józef Morozewicz, crystallography (Georg Wulff), and applied and theoretical geology (Dmitro M. …”
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