Geographic Distribution of HCV Genotypes and Efficacy of Direct-Acting Antivirals in Chronic HCV-Infected Patients in North and Northeast China: A Real-World Multicenter Study by Wencong Li, Jing Liang, Jihong An, Lingdi Liu, Yihui Hou, Lu Li, Wen Zhao, Luyao Cui, Ningning Xue, Zaid Al-Dhamin, Tao Han, Yuemin Nan, Liaoyun Zhang

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Pembrolizumab hybrid dosing is non-inferior to flat dosing in advanced non-small cell lung cancer: a real-world, retrospective bicenter cohort study by Egbert F Smit, Willemijn S M E Theelen, Michiel M Smeenk, Vincent van der Noort, Jeroen M A Hendrikx, Hanieh Abedian Kalkhoran

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Evaluating the Benefit of Home Support Provider Services for Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea: Protocol for an Ambispective International R... by Sarah Alami, Manuella Schaller, Sylvie Blais, Henry Taupin, Marta Hernández González, Frédéric Gagnadoux, Paula Pinto, Irene Cano-Pumarega, Lieven Bedert, Ben Braithwaite, Hervé Servy, Stéphane Ouary, Céline Fabre, Fabienne Bazin, Joëlle Texereau

“…ObjectiveThe AWAIR study aims to evaluate and compare the impact of different home support provider service levels on PAP adherence and persistence in 4 European countries. MethodsThis real-world, ambispective, cohort study—conducted in France, Belgium, Spain, and Portugal—will recruit adults with OSA who started PAP therapy between 2019 and 2023 and were followed by an Air Liquide Healthcare home support provider. …”
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Dream Knowledge – Understanding the Dreamworld Utilizing the Medicine Wheel by John T. Ward

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The Lobé Waterfall, an exceptional geocultural heritage on the coast of cameroon between sustainable tourism and the conservation of cultural identities by Mesmin Tchindjang, Marcel Hugues Etoga

“…This article looks at the challenges of developing tourism around the Lobé Waterfall, a singular geosite at the crossroads of three coastal civilisations (Pygmy, Batanga and Mabi), proposed by the administration of Cameroon in 2006 for inclusion on the UNESCO World Heritage List. Its definitive recognition as heritage is hindered by the prevarications of the decision-makers who favour industrialisation over integrated management and sustainable tourism, as recommended by the UNWTO and the UNIDO via the COAST STEP project. …”
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On the Issue of Mobilization of Buddhist Theological School Students and Monastics for Military Rear Work during the First World War (1916–1917) (based on Materials from the State... by Bazar D. Tsybenov, Bair Ts. Gomboev

“…Researchers have little studied some aspects of the requisition of Buryats for military rear work during the First World War. The question of conscription of students of Buddhist theological schools is a complex one. …”
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Differences in the Cardiovascular Risk Assessment in Cardiology Outpatients in Mali: Comparison between Framingham Body Mass Index-Based Tool and Low-Information World Health Organ... by Bâ Hamidou Oumar, Sangaré Ibrahima, Camara Youssouf, Sidibé Noumou, Coulibaly Souleymane, Cissoko Yacouba, Sidibé Samba, Konaté Massama, Maiga Asmaou Kéita, Doumbia Coumba Thiam, Touré Mamadou, Diakité Mamadou, Menta Ichaka, Diall Ilo Bella

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Clinical trial participation, clinical care, and patient outcomes by practice setting: a real-world database analysis of patients with Chronic Lymphocytic Leukemia or Mantle Cell L... by Debora S. Bruno, Manoj Khanal, Xiaohong Li, Maricer P. Escalon, Katherine Winfree, Lisa M. Hess

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Future destinations: how people cured of hepatitis C using direct acting antiviral drugs progress in a new HCV-free world. A thematic analysis by Sarah R. Donaldson, Andrew Radley, John F. Dillon

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Overall Survival of Patients with Metastatic Renal Cell Carcinoma Following the Introduction of Targeted and Immunotherapies: A Norwegian Retrospective, Real-World Registry Data St... by Puco K, Notland CS, Szulkin R, Jonasson C, Beisland C, Johannesen TB, Solli O, Oldenburg J, Heinrich D

“…This retrospective, registry-based study provides real-world evidence on patient outcomes and treatments of the Norwegian patients with mRCC in the period from 1995 to 2018.Keywords: real-world data, immunotherapy, molecular targeted therapy, Norway, renal cell carcinoma…”
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Renoprotective Effect of Thai Patients with Type 2 Diabetes Mellitus Treated with SGLT-2 Inhibitors versus DPP-4 Inhibitors: A Real-World Observational Study by Apichaya Chanawong, Suriyon Uitrakul, Supatcha Incomenoy, Natnicha Poonchuay

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The Real-World Clinical Outcomes of Heavily Pretreated HER2+ and HER2-Low Metastatic Breast Cancer Patients Treated with Trastuzumab Deruxtecan at a Single Centre by Anna-Maria Lazaratos, Matthew Dankner, Aalya Hamouda, Soumaya Labidi, Victor Cohen, Lawrence Panasci, Jennifer E. Friedmann, François Patenaude, Cristiano Ferrario, Mark Basik, April A. N. Rose, Parvaneh Fallah

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Real-world clinical evidence of oral semaglutide on metabolic abnormalities in subjects with type 2 diabetes: a multicenter retrospective observational study (the Sapporo-Oral SEMA... by Sho Furusawa, Hiroshi Nomoto, Chiho Oba-Yamamoto, Jun Takeuchi, Miki Ito, Hiroyoshi Kurihara, Shin Aoki, Aika Miya, Hiraku Kameda, Akinobu Nakamura, Tatsuya Atsumi

“…Oral semaglutide in subjects with type 2 diabetes improved glycemic control and body weight in a real-world clinical setting.…”
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High tumor mutational burden predicts favorable response to anti-PD-(L)1 therapy in patients with solid tumor: a real-world pan-tumor analysis by Sehhoon Park, Jaeyun Jung, You Jeong Heo

“…Among the TMB-H patients, those who responded to anti-PD-L1 therapy had numerous active immune cells that infiltrated the tumor regions during the DSP analysis. …”
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Less Stringent Global Health Treaties: Insights from Various Regimes by Rafsi Azzam Hibatullah Albar

“…With the facts obtained, a contextual analysis of the diplomatic dynamics at the World Health Organization (WHO) was performed to understand the constraints of treaty-making at the main international platform for public health. …”
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Knowledge and attitude of nursing students regarding pediatric palliative care in a teaching nursing institute by Dinabndhu Barad, Kalpana Panda, Soumya Satpathy, Neelanjana Jena, Nirupama Behera, Syed Ghulam Mustafa, Jayeeta Dey, Jami Bikrant Kumar Prusty

“…Background: According to the World Health Organization, palliative care (PC) for children involves actively caring for the child’s health, mind, and spirit and supporting the family. …”
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Real-World Evidence of Clinical Outcomes of the Use of the Adalimumab Biosimilar SB5 in Rheumatic and Gastrointestinal Immune-Mediated Inflammatory Diseases: 12-Month Data from the... by Bruno Fautrel, Yoram Bouhnik, Carine Salliot, Franck Carbonnel, Mathurin Fumery, Christophe Bernardeau, Yves Maugars, Mathurin Flamant, Fabienne Coury, Ben Braithwaite, Salima Hateb, Janet Addison, the PERFUSE investigators

“…Abstract Background There is a need for published data on real-world use of SB5, an adalimumab (ADL) biosimilar approved in Europe in 2017, on the basis of evidence from pre-clinical and analytic data as well as phase I and III clinical studies demonstrating equivalent efficacy and comparable pharmacokinetics, safety and immunogenicity profiles as the reference ADL. …”
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Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era by Amy Alabaster, Jeffrey B. Velotta, Haley I. Tupper, Mark S. Walker, Yanina Natanzon

“…Conclusion: Stage IIIA NSCLC treatment is highly variable. Real-world studies can provide valuable evidence to support surgery as a treatment option for stage IIIA patients, who currently may only be offered chemoradiation with or without immunotherapy.…”
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Impact of diabetes remission or progression on the incidence of cardiovascular disease in Japan: historical cohort study using a nationwide claims database by Chihiro Shimayama, Kazuya Fujihara, Laymon Khin, Hiroki Takizawa, Chika Horikawa, Takaaki Sato, Masaru Kitazawa, Yasuhiro Matsubayashi, Takaho Yamada, Hirohito Sone

“…Abstract Background Previous studies demonstrated that diabetes remission can occur during intensive intervention and in real-world settings. However, the impact of diabetes remission in real-world settings on the incidence of cardiovascular disease (CVD) remains unclear. …”
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Clinical Utility of a Structured Program to Reduce the Risk of Health-Related Quality of Life Impairment after Discharge from Intensive Care Unit: A Real-World Experience by Angelica Venni, Francesca Ioia, Silvia Laviola, Francesca Frigieri, Alessandra Pieri, Simona Marilli, Daniela Balzi, Piercarlo Ballo, Stefano Gori, Diletta Guarducci

“…Conclusion. In this real-world analysis that lacks a control group, patients who used a program aimed at minimizing the risk of HRQoL deterioration and PICS reported a good perception of their state of health with a relatively low prevalence of PICS.…”
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