The joint effects of inflammation and renal function status on in-hospital outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis by Zhichao Huang, Xiaoyue Zhu, Xiuman Xu, Yi Wang, Yafang Zhu, Dongqin Chen, Yongjun Cao, Xia Zhang

“…The addition of WBC and eGFR to the basic model significantly improved risk prediction for post-stroke pneumonia (category-free NRI 69.0%, 95% CI 47.3%–90.7%; IDI 5.4%, 95% CI 2.6%–8.3%) and functional outcome (category-free NRI 59.4%, 95% CI 39.2%–79.9%; IDI 5.3%, 95% CI 2.9%–7.8%). Similarly, when we added CRP and eGFR to the basic model with conventional risk factors, the risk discrimination and prediction for post-stroke pneumonia and functional outcome was also significantly improved. …”
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Elevated D-dimer on admission may predict poor prognosis in childhood influenza associated encephalopathy by Huizhen Wang, Lingkong Zeng, Xingfeng Cheng, Hui Li, Hong Zhang, Yuanmei Shi, Yong Zhang, Changjian Li

“…After binary logistic regression analysis, it was concluded that D-dimer was an independent risk factor for poor prognosis (odds ratio = 1.440, 95% confidence interval 1.052–1.972, P = 0.023), and the area under the curve (95% confidence interval) was 0.802 (0.680–0.924), P < 0.001. When D-dimer was ≥ 1.18 mg/L FEU, the occurrence of poor prognosis was predicted with sensitivity and specificity of 65.4% and 96.7%, respectively. …”
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Albumin corrected anion gap and clinical outcomes in elderly patients with acute kidney injury caused or accompanied by sepsis: a MIMIC-IV retrospective study by Yongbin Wang, Lei Zhong, Jie Min, Jianhong Lu, Jinyu Zhang, Jiajun Su

“…Abstract Background Elderly acute kidney injury (AKI) occurring in the intensive care unit (ICU), particularly when caused or accompanied by sepsis, is linked to extended hospital stays, increased mortality rates, heightened prevalence of chronic diseases, and diminished quality of life. …”
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Water Quality Assessment of Rivers in Aquatic Eco-environmental Function Regions in Changzhou City by WANG Xuesong, ZHANG Ge, LI Ying, XU Jinqian, CAI Yongjiu

“…In 2018,57 monitoring sections were arranged for a quarterly water quality survey in Changzhou,which can help grasp the water quality of 13 aquatic eco-environmental function regions.The current situation,characteristics of spatial heterogeneity,and seasonal changing laws of main water quality indicators are evaluated by multiple methods such as the water quality grade analysis,comprehensive water quality identification index (WQII) method,redundancy analysis,and principal component analysis.In this way,we can explore the major influencing factors of water quality.The results are as follows:① In 2018,the water quality of rivers in Changzhou City was mainly classified as Grade IV according to the Environmental Quality Standards for Surface Water (GB 3838—2002),which indicates the poor water quality.② The results show significant spatio-temporal difference in the concentration of main water quality indicators,and the water quality in the western hills is better than that in the eastern plains.The grade of water quality is higher in summer and autumn than in spring and winter.③ From the perspective of aquatic eco-environmental function regions,the water quality of III-09 (ecologically Grade III), IV-02 (ecologically Grade IV),and IV-03 (ecologically Grade IV) regions in the eastern urban area is poor,while the water quality of I-02 (ecologically Grade I), II-01 (ecologically Grade II),III-08 (ecologically Grade III) regions in the west is good.The grades of aquatic eco-environmental function regions are highly consistent with the water quality,which proves that the function regions can provide scientific reference for the monitoring, assessment,and environmental management of water quality.④ The redundancy analysis shows that the land for construction is the main influencing factor in the deterioration of water quality.The increase in the relative proportion of arable land and the decrease in the aquatic area closely correlate with the deterioration of water quality when the scale is over 2,000 m.⑤ The principal component analysis indicates that the five-day biochemical oxygen demand,COD,and permanganate index have high interpretation rates.This shows that the water quality of rivers in Changzhou City is mainly affected by organic pollution and eutrophication. …”
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Application of the flipped classroom model based on Bloom’s Taxonomy of Educational Objectives in endodontics education for undergraduate dental students by Yaru Wei, Zhengjun Peng

“…The length of study time prior to class under the flipped classroom model was longer than when using the traditional lecture method (t = 3.165, p = 0.003), but the flipped classroom model shortened review time after class (t = 4.038, p = 0.001). …”
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Management of Irritable Bowel Syndrome: Novel Approaches to the Pharmacology of Gut Motility by Carmelo Scarpignato, Iva Pelosini

“…Besides decreasing colonic sensitivity to distension, these drugs prolong intestinal transit and may be particularly useful in diarrhea-predominant IBS. Finally, when administered in small pulsed doses, octreotide, besides reducing the perception of rectal distension, accelerates intestinal transit, although other evidence disputes such an effect.…”
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Prevalence of prolonged transitional neonatal hypoglycemia and associated factors in Ethiopia: A systematic review and meta-analysis. by Solomon Demis Kebede, Amare Kassaw, Tigabu Munye Aytenew, Kindu Agmas, Demewoz Kefale

“…Similarly, prevalence estimates were comparable when using RBS thresholds of <47 mg/dL (21%; 95% CI: 16-27) and <40 mg/dL (18%; 95% CI: 15-22). …”
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DNA PROTECTIVE ACTIVITY OF Artemisia spp HAIRY ROOT EXTRACTS by Duplij V., Afanasieva K., Chopei M., Matvieieva N. A.

“…At the same time, there were no significant differences in the degree of protection of plasmid DNA from damage (percentage of supercoiled DNA) when extracts from hairy root lines of A. vulgaris and A. tilesii were added to the reaction mixture. …”
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Extended-release amphetamine (Dyanavel XR) is associated with reduced immediate-release supplementation in adults with ADHD, regardless of baseline patient variables: a retrospecti... by Joel L. Young, Richard N. Powell, Anna Powell, Lisa L. M. Welling, Lauren Granata, Jaime Saal, Margot Nash

“…This relationship held when controlling for baseline IR use. Regardless of whether patients supplemented with an IR, they demonstrated improved ADHD symptoms as measured by the ADHD Symptom and Side Effect Tracking (ASSET) scale after 90 days (d = 0.68 in patients with IR, d = 0.39 in patients without IR). …”
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Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity by Matthew C. Austin, Charanya Muralidharan, Saptarshi Roy, Justin J. Crowder, Jon D. Piganelli, Amelia K. Linnemann, Amelia K. Linnemann

“…We also demonstrate that HLA-I is upregulated in EndoC β-cells when autophagic degradation is inhibited. This effect was observed under both basal and IFNα stimulated conditions. …”
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Feasibility and Safety of the C1 “Zero Angle” Screw: A Novel “In–Out–In” Technique for Atlantoaxial Dislocation by Zexing Chen, Xinzhao Huang, Xiaobao Zou, Peirong Lian, Guoqiang Liu, Junlin Chen, Changrong Zhu, Xiangyang Ma

“…No instance of C1ZAS placement‐related VA injury or dural laceration was observed. Conclusions When the placement of C1 PS is not feasible in patients with AAD and unilateral/bilateral narrow C1 pedicles, C1ZAS placement with “in–out–in” technique can be considered an effective alternative option, providing tricortical or quadricortical purchase for rigid fixation of the atlas.…”
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Correlation and predictive value of novel anthropometric indicators with adult sarcopenia and sarcopenia obesity by Xue Wu, Ziang Chen, Yuanhui Zhao, Hong Ren

“…The prevalence of these conditions is higher among middle-aged men of a given age when contrasted with women at the age of 40. All anthropometric indexes demonstrated a positive correlation with the onset of SA and SO, with the association with waist-to-height ratio (WHtR) showcasing a heightened strength subsequent to the adjustment for all covariates. …”
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Overlying strata movement law and rockburst prevention & control for fully mechanized top coal caving face in extra-thick coal seams by Hai Rong, Longyue He, Yadi Wang, Xiangzhi Wei, Shilong Wei, Suihan Yang, Jincheng Li, Linlin Chen

“…The goaf of the 12,220 working face in the north of the working face is a crucial reason for the support resistance of the upper part of the 12,240 working face being greater than that of the middle part and the middle part being greater than that of the lower part. When the working face advances 20–30 m, a distinct pressure accumulation area emerges in the middle of the working face and is regularly distributed as the working face advances. …”
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Scoping review of infectious disease prevention, mitigation and management in passenger ships and at ports: mapping the literature to develop comprehensive and effective public hea... by Lemonia Anagnostopoulos, Sotirios Vasileiadis, Leonidas Kourentis, Zacharoula Bogogiannidou, Ioanna Voulgaridi, Gordon Nichols, Fani Kalala, Matthaios Speletas, Christos Hadjichristodoulou, Varvara A. Mouchtouri, the EU HEALTHY SAILING project

“…While outside the review’s scope, measures may impact travellers’ mental health, necessitating strategies when designing and implementing PMM measures.…”
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The effect of smoking on the immediate effectiveness of induction chemotherapy in the combined treatment of HPV-associated oropharyngeal cancer by P. V. Golubev, L. V. Bolotina, A. R. Gevorkov, T. I. Deshkina

“…Differences were considered reliable at p &lt; 0.05.Results. When evaluating the objective response to treatment, it was revealed that disease control was achieved in 33 (97 %) patients from group 1 and in all 34 (100 %) patients from group 2. …”
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Transcranial Doppler sonography follow-up study in mild vascular cognitive impairment. by Mariagiovanna Cantone, Manuela Pennisi, Giuseppe Lanza, Raffaele Ferri, Francesco Fisicaro, Francesco Cappellani, Emanuele David, Vito Nicosia, Klizia Cortese, Giovanni Pennisi, Valentina Puglisi, Rita Bella

“…MBFV, PSV, and EDV showed a significant increase in PSV and PI and a reduction in EDV. When focused to younger patients (<65 years), we confirmed the significant worsening of both MoCA and StroopT but not HDRS, as well as the significant changes in PI and RI. …”
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MicroRNA-21-5p Reduces Hypoxia/Reoxygenation-Induced Neuronal Cell Damage through Negative Regulation of CPEB3 by Bin Wang, Ping Yu, Wei Lin, Zhaohui Zhai

“…The luciferase reporter gene experiment verified that CPEB3 is the target of miR-21-5p (P<0.05). When coexpressing miR-21-5p mimic and CPEB3 in the cells, the protective effects of miR-21-5p under H/R were reversed (all P<0.05), and the activation of the EGFR/PI3K/AKT pathway was also inhibited (all P<0.05). …”
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Estimating and forecasting daily reference crop evapotranspiration in China with temperature-driven deep learning modelsMendeley Data by Jia Zhang, Yimin Ding, Lei Zhu, Yukuai Wan, Mingtang Chai, Pengpeng Ding

“…By integrating location and seasonality information into the training set, we found a notable improvement in the accuracy of ETo estimating, with the average Root Mean Square Error (RMSE) of the five DL models decreasing from 0.55 mm d−1 to 0.48 mm d−1. Furthermore, when we directly employed a larger volume of weather forecast data to train the models, the forecasting accuracy of ETo was significantly improved, and among the five DL models, GRU performs the best. …”
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Genomic strategies to facilitate breeding for increased β-Glucan content in oat (Avena sativa L.) by Sumandeep Kaur Bazzer, Guilherme Oliveira, Jason D. Fiedler, Raja Sekhar Nandety, Jean-Luc Jannink, Melanie Caffe

“…The overall GWAS identified 73 loci, of which 15 coincided with loci identified for individual environments and 37 coincided with previously reported β-glucan QTLs not identified when performing the GWAS in single years. In addition, 21 novel loci were identified that were not reported in the previous studies. …”
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Seroprevalence of Malaria and Hepatitis B Coinfection among Pregnant Women in Tamale Metropolis of Ghana: A Cross-Sectional Study by Gideon Kofi Helegbe, Paul Armah Aryee, Baba Sulemana Mohammed, Anthony Wemakor, David Kolbila, Abdul-Wahid Abubakari, Salam Askanda, Rashid Alhassan, Collins Barnie, Afua Aboagyewaa Donkoh, Ernest Ofosu

“…Mal/HBV coinfection was higher (0.7%) when compared with Mal/HIV (0.1%), Mal/syphilis (0.0%), HBV/HIV (0.0%), HBV/syphilis (0.1%), and HIV/syphilis (0.0%) coinfections. …”
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