Permanent aquifer storage loss from long-term groundwater withdrawal: A case study of subsidence in Bandung (Indonesia) by Michelle Rygus, Marco Bianchi, Alessandro Novellino, Ekbal Hussain, Ahmad Taufiq, Steven Reinaldo Rusli, Dwi Sarah, Claudia Meisina

“…Continued industrial groundwater extraction, primarily from the deeper, confined aquifer, has resulted in permanent aquifer storage loss totalling 7.2 km3. …”
Get full text

Accessing medical records for research in South African public hospitals: a reflective narrative by Daphney Nozizwe Conco, Boitumelo Komane, Emelda Boikanyo, Zinhle Khadija Maneli, Mothupi Boikanyo, Sharon Fonn

“…The themes that emerged from the field reports and debriefing sessions prompted us to delve deeper into the research process. To explore these themes, we conducted a focus group discussion (FGD) with all researchers. …”
Get full text

Sex-Specific Differences in the Pathophysiology of Hypertension by Hannah Zhang, Pawan K. Singal, Amir Ravandi, Inna Rabinovich-Nikitin

“…Understanding the sex-specific differences in fat metabolism may provide deeper insights into the patho-mechanisms associated with hypertension and lead to more comprehensive sex-specific care.…”
Get full text

The protective effects of peptides from Chinese baijiu on AAPH-induced oxidative stress in HepG2 cells via Nrf2-mediated signaling pathway by Jiaying Huo, Yuezhang Ming, Huifeng Li, Anjun Li, Jiwen Zhao, Mingquan Huang, Weizheng Sun, Jihong Wu, Jinglin Zhang

“…These findings provide the molecular basis for the effects of antioxidant peptides derived from Chinese baijiu, which is important for a deeper understanding of the relationship between human health and moderate drinking.…”
Get full text

Effect of feedback-integrated reflection, on deep learning of undergraduate medical students in a clinical setting by Zainab Maqsood, Madiha Sajjad, Raheela Yasmin

“…Conclusion The findings highlight the effectiveness of feedback-integrated reflection versus reflection alone in fostering deeper learning by improving higher-order MCQ scores in a gynecologic setting in the undergraduate medical education. …”
Get full text

Supporting older adults with mobility disabilities through voice-activated digital assistants and smart home technologies by Jaewon Kang, Emma Lachs, Kathryn Huang, Laura A. Rice, Wendy A. Rogers

“…We conducted in-depth interviews to gain deeper insights into their experiences and perspectives. …”
Get full text

Case Report: Clinical awareness about the effect of laser interstitial thermal therapy on pediatric high-grade brain tumors after radiotherapy by Sandra Fernandes Dias, Markus F. Oertel, Ana Guerreiro Stücklin, Nicolas U. Gerber, Elisa Colombo, Tristan P. C. van Doormaal, Niklaus Krayenbühl

“…The tumor expansion following LITT in these two patients should drive a deeper awareness of the effect of radiation and LITT on the tumor-environment. …”
Get full text

Extracellular electron transfer genes expressed by candidate flocking bacteria in cable bacteria sediment by Jamie J. M. Lustermans, Mantas Sereika, Laurine D. W. Burdorf, Mads Albertsen, Andreas Schramm, Ian P. G. Marshall

“…This community, found in deeper anoxic sediment layers, is involved in sulfur, carbon, and metal (in particular Fe) cycling and indirectly utilizes oxygen here by extracellularly transferring electrons to cable bacteria.IMPORTANCECable bacteria are ubiquitous, filamentous bacteria that couple sulfide oxidation to the reduction of oxygen at up to centimeter distances in sediment. …”
Get full text

Value-based healthcare for social insurance medicine: key enablers for adoption in practice by Sylvia J van der Burg-Vermeulen, Philip J van der Wees, Jan L Hoving, Nina Zipfel, Marijke Melles, Marije E Hagendijk

“…Future research should delve deeper into these seven key enablers to facilitate the adoption of VBHC, and thereby promote value creation in the practice of SIM.…”
Get full text

Will Climate Change Alter the Swimming Behavior of Larval Stone Crabs?: A Guided-Inquiry Lesson by Abigail L. Smith, Jessyca LaBadie, Aly Busse, Emilie Solomon, Casie Farrell, Daniel M. Holstein, Zuo George Xue, Philip M. Gravinese

“…As larvae develop offshore, they become less sensitive to certain abiotic stimuli, which promotes a deeper depth distribution that may expose them to variable current speeds, thus influencing the direction of advection (horizontal movement). …”
Get full text

Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data by Caitlin Guccione, Lucas Patel, Yoshihiko Tomofuji, Daniel McDonald, Antonio Gonzalez, Gregory D. Sepich-Poore, Kyuto Sonehara, Mohsen Zakeri, Yang Chen, Amanda Hazel Dilmore, Neil Damle, Sergio E. Baranzini, George Hightower, Teruaki Nakatsuji, Richard L. Gallo, Ben Langmead, Yukinori Okada, Kit Curtius, Rob Knight

“…Abstract As next-generation sequencing technologies produce deeper genome coverages at lower costs, there is a critical need for reliable computational host DNA removal in metagenomic data. …”
Get full text

Unlocking the interactive potential of digital models with game engines and visual programming for inclusive Vr and web-based museums by Fabrizio Banfi, Daniela

“…By supporting a diverse range of devices—including desktop computers, VR headsets, and mobile phones and tablets—these solutions aim to expand accessibility, foster inclusivity, and promote a deeper, more immersive engagement with cultural heritage. …”
Get full text

Increasing atmospheric evaporative demand across the Tibetan plateau and implications for surface water resources by Shiqin Xu, Dennis P. Lettenmaier, Tim R. McVicar, Pierre Gentine, Hylke E. Beck, Joshua B. Fisher, Zhongbo Yu, Ningpeng Dong, Akash Koppa, Matthew F. McCabe

“…Our findings provide a deeper understanding of the accelerating hydroclimatic changes and their impact on surface water resources in the Tibetan Plateau.…”
Get full text

Study of Fire Plume Behavior and Maximum Ceiling Temperature Rise in a Curved Tunnel Driven by the Coupling of Blockage Effect and Longitudinal Ventilation by Xin Zhang, Jie Li, Hao He, Xiaofeng Chen, Kai Zhu, Mingjian Yin, Ying Cao, Ke Wu

“…This work highlights the multi-dimensional and non-stable plume behavior pattern in a complex tunnel fire scenario, thus providing a deeper understanding to improve the classical tunnel fire dynamic system.…”
Get full text

Unknown issues of digitalizing the tax domain by Dimitrijević Marina

“…Digitalization of the taxation domain facilitates the work of tax authorities and compliance with tax regulations, strengthens the state's digital tax power, empowers the function of tax control of taxpayers, digitally and technologically shapes the tax reality, and gradually paves the "path" for a wider and deeper presence of tax authority in the taxpayer's life and business. …”
Get full text

Magma evolution during the post-rift phase of the Santos Basin, Brazil: petrogenesis and geochemistry of ∼126–121 ma basalts and diabases by Wenyuan He, Hongping Wang, Jinglin Su, Wangquan Wang, Junfeng Zhao, Guoping Zuo, Tongkui Wang, Liu Yang, Kangxu Ren, Chaofeng Wang, Jian Zhao, Yuan Guo, Yonggang Zhang, Jing Sun

“…The geochemical analysis hints that the older basalts and diabases were likely derived from the asthenospheric mantle, whereas the younger ones display a geochemical mix indicative of contributions from both the deeper asthenosphere and the subcontinental lithospheric mantle (SCLM), or possibly from crustal contamination. …”
Get full text

Exploring salivary gene expression clusters: A bioinformatics approach for advanced diagnosis and prognosis in head and neck squamous cell carcinoma by Rajesh Parsanathan, Rishaba Byju, D.S. Prabakaran

“…The aim is to identify critical genes and their protein-protein interactions through bio-computational analyses, contributing to a deeper understanding of HNSCC progression. Ultimately, the hypothesis anticipates the discovery of novel molecular signatures in saliva, potentially enhancing early detection and prognostic precision in head and neck squamous cell carcinoma. …”
Get full text

Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells Support CD34pos Hematopoietic Stem Cell Propagation and Suppress Inflammatory Reaction by Mohsen Moslem, Irina Eberle, Iuliia Weber, Reinhard Henschler, Tobias Cantz

“…Considering functional capabilities, iPSC-MSCs provided supportive feeder layer for CD34+ hematopoietic stem cells’ self-renewal and colony forming capacities. …”
Get full text

Modeling of Blood Flow Dynamics in Rat Somatosensory Cortex by Stéphanie Battini, Nicola Cantarutti, Christos Kotsalos, Yann Roussel, Alessandro Cattabiani, Alexis Arnaudon, Cyrille Favreau, Stefano Antonel, Henry Markram, Daniel Keller

“…We found that local vasodilation from astrocyte activity increased blood flow, especially in capillaries, exhibiting a layer-specific response in deeper cortical layers. Additionally, the highest blood flow variability occurred in capillaries, emphasizing their role in cerebral perfusion regulation. …”
Get full text

Supraglacial Lake Depth Retrieval from ICESat-2 and Multispectral Imagery Datasets by Quan Zhou, Qi Liang, Wanxin Xiao, Teng Li, Lei Zheng, Xiao Cheng

“…Our results show that machine learning-based algorithms achieve better accuracy than traditional regression or physics-based methods do, especially for deeper lakes. The best accuracy was achieved when extreme gradient boosting was applied to a Sentinel-2 L1C image, with root mean square error, mean absolute error, and median absolute error values of 0.54 m, 0.43 m, and 0.36 m, respectively. …”
Get full text