Orphan nuclear receptor NR2E3 is a new molecular vulnerability in solid tumors by activating p53 by Yidan Wang, Todd G. Kroll, Linhui Hao, Zhi Wen

“…Here, we demonstrate that the full-length protein isoform of NR2E3 instead of its short isoform activates wild-type p53 and is capable of rescuing certain p53 mutations in various cancer cell lines. …”
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Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis by Valentina Zagardo, Mandara Harikar, Gianluca Ferini

“…As the first systematic review on this topic, our study faced considerable source heterogeneity, precluding a meta-analysis. Instead, we analyzed treatment trends by demographics and tumor characteristics, providing a comprehensive overview and encouraging further research in this area.…”
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Efficacy and safety of tenofovir and entecavir in patients with chronic hepatitis B-related cirrhosis: a systematic review and meta-analysis by Lu Cao, Li Li, Lixing Yang, Nan Zhou, Yu Zhang

“…Tenofovir did not significantly cause renal dysfunction, but instead improved estimated glomerular filtration rate levels compared with entecavir. …”
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Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells by Lisa Nguyen, Lucas-Sebastian Spitzhorn, James Adjaye

“…As urine-derived renal progenitor cells can be easily obtained from cells shed into urine, the generation of 3D-NPCs directly from renal progenitor cells instead of pluripotent stem cells or kidney biopsies holds a great potential for the use in nephrotoxicity tests, drug screening, modelling nephrogenesis and diseases.…”
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A facile synthesis by spark plasma sintering of mobile lithium ions into oxynitride glass-ceramic matrix: Insight and perspective by Sharafat Ali, Abbas Saeed Hakeem, Hussain Alslman, Natalia Anna Wójcik

“…The quest for efficient energy storage solutions has led to the development of solid-state Li-on batteries (SSBs), which utilize solid-state electrolyte (SSE) materials instead of organic liquid electrolytes. This study investigates the effect of increasing Li content in a Ca11Al14Si16O49N10 glass-ceramic material on its structural, thermal, physical, and electrical properties. …”
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Transfer of Organochlorine Pesticide Residues during Household and Industrial Processing of Ginseng by Peiling Wu, Mengying Gu, Yujie Wang, Jian Xue, Xiaoli Wu

“…Generally, people are more inclined to take the household- or industrial-processed ginseng products, instead of eating them directly. To investigate the intake of pesticides along with ginseng more specifically, we simulated two household processing methods (boiling and brewing) and two industrial processing methods (ethanol refluxing and boiling combined with resin purification) and then calculated the transfer rates of five organochlorine pesticide (OCP) residues in ginseng. …”
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How to Manage Low Estriol Levels in Pregnancies, One Center Experience by Elif YILMAZ GULEC, Alper GEZDIRICI, Akif AYAZ, Fatma Nihal OZTURK, Ibrahim POLAT

“…We aimed to investigate the outcomes of pregnancies with low uE3 levels in Down syndrome screening and emphasize the high prevalence of STS deficiency instead of SLOS in such cases. Methods: Fifteen pregnancies with very low uE3 levels and high risk for trisomy and/or SLOS in screening tests were evaluated and tested for STS deficiency and SLOS. …”
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NEW «PARASITIC CLASS»: ON THE CONCEPT OF MIKHAIL VOSLENSKY by Сергій САВЧЕНКО, Катерина ПРОКОФ’ЄВА, Оксана РЕШЕТІЛОВА

“…He refutes the thesis about the nomenklatura’s modernizing role, pointing instead to the robust developmental dynamics of pre-revolutionary Russia. …”
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Response Surface Methodology and Textural Profile Analysis for Optimization of Fruit Peel-Based Extruded Snack (Elbow Macaroni) by Pragya Mishra, Ena Gupta, Karishma Gupta

“…The proximate composition of optimized fruit peel macaroni was reported to have 5.06, 9.7, 2.7, 1.33, 1.42, and 79.79 percent of moisture, protein, fibre, fat, ash, and carbohydrate, respectively. Thus, instead of disposing and causing environmental hazards, the fruit peels act as promising sources for food supplementation and can be utilized for the nutritional enrichment of snack foods. …”
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Legality of bringing to administrative responsibility for an offense under Art. 130 Code of Ukraine on Administrative Offenses: retrospective analysis by K. O. Chyshko

“…It was stated that the clarification provided in this regard by the Committee on Law Enforcement of the Verkhovna Rada of Ukraine is neither a source of law nor a normative legal act and is not binding, but instead serves a recommendatory function, therefore, the involvement of persons for committing a specific criminal offense under the procedure of proceedings on administrative offenses has no legal grounds.…”
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Economy of Fertilizer Nitrogen through Organic Sources in Rain-Fed Rice-Legume Cropping Systems in West Bengal, India by A.M. Puste, S. Bandyopadhyay, D.K. Das

“…Field experiments were conducted at a farmers’ plot adjacent to the Regional Research Station, red and laterite zone, Sub-center Sekhampur (Birbhum district) of West Bengal, India, situated 23° 24' N latitude, 87° 24' E longitude, to study the effect of different bio- and organic sources of nutrients instead of total fertilizer N in terms of crop productivity in the sequence and building up of soil fertility. …”
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Non-Toxic Buffer Layers in Flexible Cu(In,Ga)Se2 Photovoltaic Cell Applications with Optimized Absorber Thickness by Md. Asaduzzaman, Md. Billal Hosen, Md. Karamot Ali, Ali Newaz Bahar

“…The simulation results with ZnS and ZnO based buffer layer materials instead of using CdS indicate that the cell performance would be better than that of the CdS buffer layer based cell. …”
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Wood Chip Incorporation in Almond Orchard Planting Berms Increased Gravimetric Water Content, Soil CO2 Efflux, and Fine Root Length Density by Hana You, Paul Martinez, Mae Culumber, Brent Holtz, Astrid Volder

“…Incorporation of chipped woody material into soil instead of burning or transporting wood chips (WCs) off-site is a practical solution to dispose of old orchard trees. …”
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Application of a Plug-and-Play Immunogenicity Assay in Cynomolgus Monkey Serum for ADCs at Early Stages of Drug Development by Montserrat Carrasco-Triguero, Helen Davis, Yuda Zhu, Daniel Coleman, Denise Nazzal, Paul Vu, Surinder Kaur

“…Secondly, we propose a cut point methodology based on animal specific baseline variability instead of a population data approach. This assay showed good sensitivity, drug tolerance, and reproducibility across a variety of antibody-derived biotherapeutics without the need for optimization across molecules.…”
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Carbonized Aramid Fiber as the Adsorbent for In-Tube Solid-Phase Microextraction to Detect Estrogens in Water Samples by Xiaoxiao Zhu, Yijun Zhang, Pengfei Liu, Xiuzhi Bai, Na Chen, Yuping Zhang

“…The prepared fiber was packed in a stainless-steel tube instead of the sample loop of a six-port and tested for the extraction of five environmental estrogen hormones coupled with high-performance liquid chromatography. …”
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A Multi-Resonant based reference feedforward adaptive voltage control for Grid-Forming inverter in island mode to compensate system uncertain and harmonic distortions by Renzhi Huang, Zaijun Wu, Xueyong Xu, Xiangjun Quan, Mingfei Li, Zichen Wang, Mengnan Liu

“…Thanks to its linearization, the stability of the strategy is ensured by the mature linear control theory instead of the Lyapunov stability theory. Then, the principles of parameter selection based on the root locus method are introduced to improve the dynamic performance of this technique. …”
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Arsenic and fifteen other metal (loid)s exposure of children living around old mines in the south of France by Igor Pujalté, Zeno Loi, Alice Bernard, Lionel Moulis, Sophie Delpoux, Jacques Gardon

“…Proximity to mining sites did not increase arsenic exposure (r Pearson = 0.142). Instead, factors like age, seafood consumption, and environmental conditions were more influential. …”
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Design of a new hydrokinetic turbine simulation model based on the extended power coefficient concept by Manuel Rico-Secades, Antonio Javier Calleja-Rodríguez, Aitor Fernández-Jiménez, Eduardo Álvarez-Álvarez, Fher Said Macedo-Garcia, Jaime Arau-Roffiel

“…Even, a methodology has been developed to dynamically find the values of the extended power coefficient according to the blockage produced in the channel.Moreover, and based on this extended coefficient, a hydrokinetic turbine simulation model is presented to be applied in cases of flow blockage instead of the actual models of the electrical simulators based in the classical coefficient. …”
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Electron–phonon coupling and coherent energy superposition induce spin-sensitive orbital degeneracy for enhanced acidic water oxidation by Yanfeng Shi, Lupeng Wang, Miao Liu, Zuozheng Xu, Peilin Huang, Lizhe Liu, Yuanhong Xu

“…Different from traditional nanostructuring, here we employ an innovative microwave-mediated electron–phonon coupling technique to assemble specific Ru atomic patterns (instead of random Ru-particle depositions) on Mn0.99Cr0.01O2 surfaces (RuMW-Mn1-xCrxO2) in RuCl3 solution because hydrated Ru-ion complexes can be uniformly activated to replace some Mn sites at nearby Cr-dopants through microwave-triggered energy coherent superposition with molecular rotations and collisions. …”
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High-performance solid-state proton gating membranes based on two-dimensional hydrogen-bonded organic framework composites by Dandan Lei, Yixiang Wang, Qixiang Zhang, Shuqi Wang, Lei Jiang, Zhen Zhang

“…Here, we demonstrate solid-state hydrogen-bonded organic frameworks-based membranes to achieve high-performance ambient humidity-controlled proton gating, accomplished by switching the proton transport pathway instead of relying on conventional ion blockage/activation effects. …”
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