Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention by Sonia Youhanna, Aurino M. Kemas, Shane C. Wright, Yi Zhong, Britta Klumpp, Kathrin Klein, Aikaterini Motso, Maurice Michel, Nicole Ziegler, Mingmei Shang, Pierre Sabatier, Aimo Kannt, Hongda Sheng, Nuria Oliva‐Vilarnau, Florian A. Büttner, Brinton Seashore‐Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, Volker M. Lauschke

Get full text

Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy by Timothy J Abreo, Emma C Thompson, Anuraag Madabushi, Kristen L Park, Heun Soh, Nissi Varghese, Carlos G Vanoye, Kristen Springer, Jim Johnson, Scotty Sims, Zhigang Ji, Ana G Chavez, Miranda J Jankovic, Bereket Habte, Aamir R Zuberi, Cathleen M Lutz, Zhao Wang, Vaishnav Krishnan, Lisa Dudler, Stephanie Einsele-Scholz, Jeffrey L Noebels, Alfred L George, Atul Maheshwari, Anastasios Tzingounis, Edward C Cooper

Get full text

Nonalcoholic Fatty Liver Disease and Associated Metabolic Risks of Hypertension in Type 2 Diabetes: A Cross-Sectional Community-Based Study by Xiaoying Ding, Ying Xu, Yufan Wang, Xiaohua Li, Chunhua Lu, Jing Su, Yuhang Ma, Yuting Chen, Yanhua Yin, Lijun Zhang, Yong Wu, Yaqiong Jin, Lijun Zheng, Songmei Xu, Xiuli Zhu, Jilin Ma, Lihua Yu, Junyi Jiang, Naisi Zhao, Qingwu Yan, Andrew S. Greenberg, Qianfang Huang, Qian Ren, Haiyan Sun, Mingyu Gu, Li Zhao, Yunhong Huang, Yijie Wu, Chunxian Qian, Yongde Peng

Get full text

Expert consensus on pulpotomy in the management of mature permanent teeth with pulpitis by Lu Zhang, Chen Lin, Zhuo Chen, Lin Yue, Qing Yu, Benxiang Hou, Junqi Ling, Jingping Liang, Xi Wei, Wenxia Chen, Lihong Qiu, Jiyao Li, Yumei Niu, Zhengmei Lin, Lei Cheng, Wenxi He, Xiaoyan Wang, Dingming Huang, Zhengwei Huang, Weidong Niu, Qi Zhang, Chen Zhang, Deqin Yang, Jinhua Yu, Jin Zhao, Yihuai Pan, Jingzhi Ma, Shuli Deng, Xiaoli Xie, Xiuping Meng, Jian Yang, Xuedong Zhou, Zhi Chen

Get full text

Perioperative tislelizumab plus chemotherapy for locally advanced gastroesophageal junction adenocarcinoma (NEOSUMMIT-03): a prospective, nonrandomized, open-label, phase 2 trial by Run-Cong Nie, Shu-Qiang Yuan, Ya Ding, Yong-Ming Chen, Yuan-Fang Li, Cheng-Cai Liang, Mu-Yan Cai, Guo-Ming Chen, Wei Wang, Xiao-Wei Sun, De-Sheng Weng, Dan-Dan Li, Jing-Jing Zhao, Xiao-Jiang Chen, Yuan-Xiang Guan, Zhi-Min Liu, Yao Liang, Ma Luo, Jun Chi, Hai-Bo Qiu, Zhi-Wei Zhou, Xiao-Shi Zhang, Ying-Bo Chen

Get full text

Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals by Najwa D. Aljehani, Levi Tamming, Muhammad Yasir Khan, Rwaa H. Abdulal, Mohamed A. Alfaleh, Aishah Ghazwani, Asalah Helal, Reem M. Alsulaiman, Mohammad A. Sanki, Khalid Alluhaybi, Farah Ayman Sukareh, Rahaf H. Alharbi, Faris H. Alyami, M-Zaki ElAssouli, Salima Shebbo, Wesam H. Abdulaal, Abdullah Algaissi, Ahmad Bakur Mahmoud, Mohammad Basabrain, Diana Duque, Jegarubee Bavananthasivam, Wangxue Chen, Lisheng Wang, Simon Sauve, Turki S. Abujamel, Tarfa Altorki, Rowa Alhabbab, Anh Tran, Xuguang Li, Anwar M. Hashem

Get full text

Association of Total Mortality and Cardiovascular Endpoints With the Timing of the First and Second Systolic Peak of the Aortic Pulse Wave by Yi‐Bang Cheng, De‐Wei An, Lucas S. Aparicio, Qi‐Fang Huang, Yu‐Ling Yu, Chang‐Sheng Sheng, Teemu J. Niiranen, Fang‐Fei Wei, José Boggia, Katarzyna Stolarz‐Skrzypek, Natasza Gilis‐Malinowska, Valérie Tikhonoff, Wiktoria Wojciechowska, Edoardo Casiglia, Krzysztof Narkiewicz, Wen‐Yi Yang, Jan Filipovský, Kalina Kawecka‐Jaszcz, Ji‐Guang Wang, Tim S. Nawrot, Yan Li, Jan A. Staessen, the International Database of Central Arterial Properties for Risk Stratification (IDCARS) Investigators

Get full text

Ground-based Reconnaissance Observations of 21 Exoplanet Atmospheres with the Exoplanet Transmission Spectroscopy Imager by Ryan J. Oelkers, Luke M. Schmidt, Erika Cook, Mary Anne Limbach, D. L. DePoy, J. L. Marshall, Jimmy Ardoin, Mitchell Barry, Evan Batteas, Alexandra Boone, Brant Conway, Silvana Delgado Adrande, John D. Dixon, Enrique Gonzalez-Vega, Alexandra Guajardo, Landon Holcomb, Christian Lambert, Shravan Menon, Divya Mishra, Jacob Purcell, Zachary Reed, Nathan Sala, Noah Siebersma, Nhu Ngoc Ton, Raenessa M. L. Walker, Z. Franklin Wang, Kaitlin Webber

Get full text

Biomass burning emission analysis based on MODIS aerosol optical depth and AeroCom multi-model simulations: implications for model constraints and emission inventories by M. Petrenko, M. Petrenko, R. Kahn, R. Kahn, M. Chin, S. E. Bauer, T. Bergman, H. Bian, G. Curci, B. Johnson, J. W. Kaiser, Z. Kipling, H. Kokkola, H. Kokkola, X. Liu, K. Mezuman, K. Mezuman, T. Mielonen, G. Myhre, X. Pan, X. Pan, A. Protonotariou, S. Remy, R. B. Skeie, P. Stier, T. Takemura, K. Tsigaridis, K. Tsigaridis, H. Wang, D. Watson-Parris, D. Watson-Parris, K. Zhang

Get full text

Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response by Wazim Mohammed Ismail, Jenna A. Fernandez, Moritz Binder, Terra L. Lasho, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Liguo Wang, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Seul Kee Byeon, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Keith D. Robertson, Akhilesh Pandey, Eric D. Wieben, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik

Get full text

Recent centennial drought on the Tibetan Plateau is outstanding within the past 3500 years by Yu Liu, Huiming Song, Zhisheng An, Qiang Li, Steven W. Leavitt, Ulf Büntgen, Qiufang Cai, Ruoshi Liu, Congxi Fang, Changfeng Sun, Kerstin Treydte, Meng Ren, Lidong Mo, Yi Song, Wenju Cai, Quan Zhang, Weijian Zhou, Achim Bräuning, Jussi Grießinger, Deliang Chen, Hans W. Linderholm, Ashish Sinha, Hai Cheng, Lu Wang, Ying Lei, Junyan Sun, Wei Gong, Xuxiang Li, Linlin Cui, Liang Ning, Lingfeng Wan, Thomas W. Crowther, Constantin M. Zohner

Get full text

A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases by Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Tianhao Wang, Kang Bei, Chithra Changalath, Shiny Matilda, Alex J. Rai, Renata Welc-Falęciak, Agnieszka Pawełczyk, Lucas S. Blanton, Aleš Chrdle, Andrea Fořtová, Daniel Růžek, Gheyath K. Nasrallah, Laith J. Abu-Raddadi, Duaa W. Al-Sadeq, Marah Abed Alhakim Abdallah, Daniele Lilleri, Chiara Fornara, Piera D’Angelo, Milena Furione, Maria Söderlund-Venermo, Klaus Hedman, Dimosthenis Chochlakis, Eirini Makridaki, Artemis Ntoula, Anna Psaroulaki, Angélica Escárcega-Ávila, John J. Rajasekaran

Get full text

STAGER checklist: Standardized testing and assessment guidelines for evaluating generative artificial intelligence reliability by Jinghong Chen, Lingxuan Zhu, Weiming Mou, Anqi Lin, Dongqiang Zeng, Chang Qi, Zaoqu Liu, Aimin Jiang, Bufu Tang, Wenjie Shi, Ulf D. Kahlert, Jianguo Zhou, Shipeng Guo, Xiaofan Lu, Xu Sun, Trunghieu Ngo, Zhongji Pu, Baolei Jia, Che Ok Jeon, Yongbin He, Haiyang Wu, Shuqin Gu, Wisit Cheungpasitporn, Haojie Huang, Weipu Mao, Shixiang Wang, Xin Chen, Loïc Cabannes, Gerald Sng Gui Ren, Iain S. Whitaker, Stephen Ali, Quan Cheng, Kai Miao, Shuofeng Yuan, Peng Luo

Get full text

Impacts of irrigation expansion on moist-heat stress based on IRRMIP results by Yi Yao, Agnès Ducharne, Benjamin I. Cook, Steven J. De Hertog, Kjetil Schanke Aas, Pedro F. Arboleda-Obando, Jonathan Buzan, Jeanne Colin, Maya Costantini, Bertrand Decharme, David M. Lawrence, Peter Lawrence, L. Ruby Leung, Min-Hui Lo, Narayanappa Devaraju, William R. Wieder, Ren-Jie Wu, Tian Zhou, Jonas Jägermeyr, Sonali McDermid, Yadu Pokhrel, Maxwell Elling, Naota Hanasaki, Paul Muñoz, Larissa S. Nazarenko, Kedar Otta, Yusuke Satoh, Tokuta Yokohata, Lei Jin, Xuhui Wang, Vimal Mishra, Subimal Ghosh, Wim Thiery

Get full text

Toward an integrated pantropical ocean observing system by Gregory R. Foltz, Yassir A. Eddebbar, Janet Sprintall, Antonietta Capotondi, Antonietta Capotondi, Sophie Cravatte, Sophie Cravatte, Peter Brandt, Peter Brandt, Adrienne J. Sutton, Tamaryn Morris, Juliet Hermes, Juliet Hermes, Clive R. McMahon, Michael J. McPhaden, Lev B. Looney, Lev B. Looney, Lev B. Looney, Franz Philip Tuchen, Franz Philip Tuchen, Mathew Koll Roxy, Fan Wang, Fei Chai, Regina R. Rodrigues, Belen Rodriguez-Fonseca, Belen Rodriguez-Fonseca, Aneesh C. Subramanian, Marcus Dengler, Cheyenne Stienbarger, Kathleen Bailey, Weidong Yu

Get full text

OrchidBase 6.0: increasing the number of Cymbidium (Orchidaceae) genomes and new bioinformatic tools for orchid genome analysis by You-Yi Chen, Ye Sun, Chung-I Li, Shao-Ting Lin, Hao-Chen Zheng, Zhe-Bin Zhang, Bing-Ru Lee, Chun-Lin Hsieh, Yu-Yun Hsiao, Chi-Nga Chow, Chien-Wen Yang, Wen-Chi Chang, Heming Chen, Feng-Xi Yang, Gen-Fa Zhu, Qinyao Zheng, Cheng-Yuan Zhou, Zhuang Zhao, Ye Ai, Lin-Ying Wang, Deqiang Chen, Xin He, Ming-Zhong Huang, Dong-Hui Peng, Hao Yu, Siren Lan, Zhong-Jian Liu, Wei-Sheng Wu, Wen-Chieh Tsai

Get full text

Measurement report: Exploring the variations in ambient BTEX in urban Europe and their environmental health implications by X. Liu, X. Zhang, M. Dufresne, T. Wang, L. Wu, R. Lara, R. Seco, M. Monge, A. M. Yáñez-Serrano, A. M. Yáñez-Serrano, A. M. Yáñez-Serrano, M. Gohy, P. Petit, A. Chevalier, M.-P. Vagnot, Y. Fortier, A. Baudic, V. Ghersi, G. Gille, L. Lanzi, V. Gros, L. Simon, H. Héllen, S. Reimann, Z. Le Bras, M. J. Müller, D. Beddows, S. Hou, Z. Shi, R. M. Harrison, W. Bloss, J. Dernie, S. Sauvage, P. K. Hopke, P. K. Hopke, X. Duan, T. An, A. C. Lewis, J. R. Hopkins, E. Liakakou, N. Mihalopoulos, N. Mihalopoulos, X. Zhang, A. Alastuey, X. Querol, T. Salameh

Get full text

Unveiling microbial communities with EasyAmplicon: A user‐centric guide to perform amplicon sequencing data analysis by Salsabeel Yousuf, Hao Luo, Meiyin Zeng, Lei Chen, Tengfei Ma, Xiaofang Li, Maosheng Zheng, Xin Zhou, Liang Chen, Jiao Xi, Hongye Lu, Huiluo Cao, Xiaoya Ma, Bian Bian, Pengfan Zhang, Jiqiu Wu, Renyou Gan, Baolei Jia, Linyang Sun, Zhicheng Ju, Yunyun Gao, Waqar Afzal Malik, Chuang Ma, Hujie Lyu, Yahui Li, Huiyu Hou, Yuanping Zhou, Defeng Bai, Yao Wang, Haifei Yang, Jiani Xun, Shengda Du, Tianyuan Zhang, Xiulin Wan, Kai Peng, Shanshan Xu, Tao Wen, Tong Chen, Yong‐Xin Liu

Get full text

Author Correction: Typical and extreme weather datasets for studying the resilience of buildings to climate change and heatwaves by Anaïs Machard, Agnese Salvati, Mamak P. Tootkaboni, Abhishek Gaur, Jiwei Zou, Liangzhu Leon Wang, Fuad Baba, Hua Ge, Facundo Bre, Emmanuel Bozonnet, Vincenzo Corrado, Xuan Luo, Ronnen Levinson, Sang Hoon Lee, Tianzhen Hong, Marcelo Salles Olinger, Rayner Maurício e Silva Machado, Emeli Lalesca Aparecida da Guarda, Rodolfo Kirch Veiga, Roberto Lamberts, Afshin Afshari, Delphine Ramon, Hoang Ngoc Dung Ngo, Abantika Sengupta, Hilde Breesch, Nicolas Heijmans, Jade Deltour, Xavier Kuborn, Sana Sayadi, Bin Qian, Chen Zhang, Ramin Rahif, Shady Attia, Philipp Stern, Peter Holzer

Get full text

Typical and extreme weather datasets for studying the resilience of buildings to climate change and heatwaves by Anaïs Machard, Agnese Salvati, Mamak P. Tootkaboni, Abhishek Gaur, Jiwei Zou, Liangzhu Leon Wang, Fuad Baba, Hua Ge, Facundo Bre, Emmanuel Bozonnet, Vincenzo Corrado, Xuan Luo, Ronnen Levinson, Sang Hoon Lee, Tianzhen Hong, Marcelo Salles Olinger, Rayner Maurício e Silva Machado, Emeli Lalesca Aparecida da Guarda, Rodolfo Kirch Veiga, Roberto Lamberts, Afshin Afshari, Delphine Ramon, Hoang Ngoc Dung Ngo, Abantika Sengupta, Hilde Breesch, Nicolas Heijmans, Jade Deltour, Xavier Kuborn, Sana Sayadi, Bin Qian, Chen Zhang, Ramin Rahif, Shady Attia, Philipp Stern, Peter Holzer

Get full text