Conjugates of Phthalocyanines With Oligonucleotides as Reagents for Sensitized or Catalytic DNA Modification

“…Under both sensitized and catalyzed conditions, the nucleotides <mml:math alttext="G$^{13}$"> <mml:msup> <mml:mtext>G</mml:mtext> <mml:mrow> <mml:mn>13</mml:mn> </mml:mrow> </mml:msup> </mml:math>&#8211;<mml:math alttext="G$^{15}$"> <mml:msup> <mml:mtext>G</mml:mtext> <mml:mrow> <mml:mn>15</mml:mn> </mml:mrow> </mml:msup> </mml:math> were mainly modified, providing evidence that the reaction proceeded in the double-stranded oligonucleotide. …”
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Enhancing predictive accuracy for urinary tract infections post-pediatric pyeloplasty with explainable AI: an ensemble TabNet approach by Hongyang Wang, Junpeng Ding, Shuochen Wang, Long Li, Jinqiu Song, Dongsheng Bai

“…By improving prediction accuracy, this model supports proactive interventions, reduces postoperative infections and re-obstruction rates, enhances pyeloplasty outcomes, and alleviates health and economic burdens. Level of evidence IV Case series with no comparison group.…”
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Economic-productive analysis of a mixed cattle-bubaline model mixed model in the Northern region of Corrientes Province in Argentina by Pablo Maldonado-Vargas, Vanesa Guadalupe Mierke, Liliana Laura Pellerano, Guillermo Sebastián Grimaldi, Orlando Alberto Álvarez, Natalia Mercedes Vallejos, Margarita Rosa Itatí Romero, Francisco Daniel Romero, Alexis Sebastián Bandeo, Gonzalo Enrique Tuñón, José Luis Konrad

“… The production of buffaloes has been consistently growing in Argentina, with an increase in the number of animals and spread in 19 of the 23 provinces of the country, with an evident regional grouping. The Northeastern region of Argentina contains the provinces of Corrientes, Formosa, Chaco, Misiones, and Entre Rios, where 88.89% of the buffaloes, with Corrientes having the most significant numbers of animals and farmers. …”
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gp91phox, a Novel Biomarker Evaluating Oxidative Stress, Is Elevated in Subclinical Hypothyroidism by Xiaochun Ma, Furong Wang, Xiaowen Zhen, Lifang Zhao, Li Fang, Zhenfang Dong, Wenbin Chen, Xiaoming Zhou

“…The levels of serum soluble gp91phox evidently increased in the patients with SH with a high level of LDL-C (81.52 ± 37.00 ug/mL) as compared to the healthy controls (54.98 ± 1.83ug/mL, p<0.001), controls with high level of LDL-C (61.21 ± 4.48 ug/mL, p=0.038) and SH with a normal level of LDL-C (62.82 ± 11.67ug/mL, p=0.027). …”
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It is time to tackle psychological determinants of obesity and eating disorders by Pietro Crescenzo

“…Obesity and malnutrition are two sides of the same question and they are probably one of the most evidence of social and economic inequalities in the world today [3]. …”
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AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection by Zhiyang Chen, Tingting Xie, Shuting Chen, Zhenhui Li, Su Yao, Xuanjun Lu, Wenfeng He, Chao Tang, Dacheng Yang, Shaohua Li, Feng Shi, Huan Lin, Zipei Li, Anant Madabhushi, Xiangtian Zhao, Zaiyi Liu, Cheng Lu

“…However, their prognostic value in hepatocellular carcinoma (HCC) remains controversial, with different evidence. Given the heterogeneous outcomes in patients with HCC undergoing liver resection, this study aims to develop an AI-based system to quantify CD8+ TILs and assess their prognostic value for patients with HCC. …”
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Development of Stylistics and Rhetoric in Lithuania by Irena Smetonienė, Marius Smetona

“…Teaching of rhetoric adheres to the classical canon rediscovered during the global revival of rhetoric. However, evident changes are occurring, as everything in the world undergoes reevaluation, from social relations and value systems to language. …”
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Spatial distribution and determinants of improved shared sanitation facilities among households in Ethiopia: Using 2019 mini-Ethiopian Demographic and Health Survey. by Baye Tsegaye Amlak, Daniel Gashaneh Belay

“…Although shared facilities are not classified as improved sanitation due to potential infection risks, inaccessibility, and safety concerns, this is a significant issue in developing countries like Ethiopia. Evidence on the distribution of shared sanitation services and their determinants in Ethiopia is limited. …”
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Enhancing Learners’ Engagement and Performance in Learning through E-Resources and Services: National Open University of Nigeria Students as Beneficiaries by Patricia Ngozi Ofodu, Loveth Ogoegbunam Ekwueme

“…The study also revealed that the use of electronic resources influenced the users’ class tests, assignments, seminar presentations and more, while there was also evidence of non-assistance from the use of e-resources in some students’ learning pursuits. …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…In recent years, mounting evidence indicates that NTN1 also plays a crucial role in tumorigenesis and tumor progression. …”
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Nouveaux éléments concernant l’amphithéâtre antique de Saintes (Charente-Maritime) : l’arène aux iiie et ive s. apr. J.-C. by Bastien Gissinger

“…Several indications made it possible to establish –with a reasonable degree of reliability– the date of construction of the arena in its final state, as it exists today, which totally obliterated evidence of the previous states as far as it was possible to judge within the trenches made. …”
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Tobacco Use, Risk Perceptions, and Characteristics of Adults Who Used a Heated Tobacco Product (IQOS) in the United States: Cross-Sectional Survey Study by Hui G Cheng, Brendan Noggle, Andrea R Vansickel, Edward G Largo, Pierpaolo Magnani

“…ConclusionsThis study provides evidence that THS can help adult smokers in the United States completely switch away from cigarettes or reduce smoking.…”
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Efficacy and safety of sequential therapy for primary osteoporosis with bone formation promoters followed by bone resorption inhibitors: a meta-analysis by Yuxin Liu, Xin Liu, Yuefeng Wu, Tao Luo

“…Results A total of 10 eligible articles involving 14,510 patients (7171 in the intervention group versus 7339 in the comparator group) were included for the evidence synthesis. The baseline characteristics of the two groups were similar. …”
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FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis by Amaya Lopez-Pascual, Eva Santamaria, Nuria Ardaiz, Iker Uriarte, Tiffany Palmer, Anne-Renee Graham, Celia Gomar, Roberto C. Barbero, M. Ujue Latasa, Maria Arechederra, Jesus M. Urman, Carmen Berasain, Antonio Fontanellas, Carlos L. del Rio, Maite G. Fernandez-Barrena, Paolo G.V. Martini, Joshua R. Schultz, Pedro Berraondo, Matias A. Avila

“…On the other hand, histological improvements were more evident in mice receiving APOA1 LNP-mRNA. In the EtOH/POA-AP model, FGF21 and APOA1-FGF21 LNP-mRNAs reduced serum AST levels, indicating hepatoprotective activity. …”
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Intracranial pressure monitoring in patients with spontaneous onset of orthostatic headache by Linda D’Antona, Sanjay Cheema, Dwij Mehta, Fion Bremner, Laurence Dale Watkins, Ahmed Kassem Toma, Manjit Singh Matharu

“…Specific cut-offs for low and high ICP states were predetermined based on the best available current evidence. Results Thirty-eight patients (23 females, mean age 41 years ± 14SD) were identified. …”
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Validation of the Chronic Liver Disease Questionnaire for MASH (CLDQ-MASH) by Zobair M. Younossi, Maria Stepanova, Issah Younossi, Andrei Racila

“…Impact and implications:: The new criteria for metabolic dysfunction-associated steatohepatitis (MASH) are different from those previously used for non-alcoholic steatohepatitis so the evidence collected for the previous criteria need to be revisited, including disease-specific instruments for assessment of health-related quality of life. …”
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Improving Outcomes and Quality of Life for Patients With Hand and Foot Eczema: Randomized Study of a Patient-Centered Monitoring App by Aimee Bruch, Wanja Weigandt, Yannic Schardt, Raphael Herr, Johannes Benecke, Astrid Schmieder

“…ConclusionsThis study provides further evidence that digital health apps can provide valuable support in improving patient clinical outcomes and management, especially as the app-based assessment of hand and feed images appears to be reliable. …”
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INSTITUTIONAL GLOBALIZATION AS A SYSTEM OF INTEGRATION THE PHENOMENON OF THE POSTMODERN DEVELOPMENT by V. V. Zinchenko

“…The population is invited to wait and endure, i.e. plays the role of the object of political and economic manipulation. …”
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Impact of hepatic steatosis on the efficacy of antiviral treatment for chronic hepatitis B and the establishment of predictive model: a cohort study by Guanghui Ren, Kaining Jia, Shi Yin, Yunpeng Guan, Qingwei Cong, Ying Zhu

“…This is particularly evident among individuals who are negative for HBeAg (48w: 24.2% vs 12.2%, p = 0.005). …”
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Analisa Sentimen Financial Technology Peer To Peer Lending Pada Aplikasi Koinworks by Rousyati Rousyati, Windu Gata, Dany Pratmanto, Nia Kusuma Wardhani

“…The benefits of this research are to help the management of Koinworks applications regarding positive or negative opinions of application users and can provide empirical evidence for related theories so that they can be contributed to the development of subsequent theories. …”
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