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  1. 17741
  2. 17742

    Prevalence and Associated Factors of Overweight and Obesity among Primary School Children Aged 7–17 Years in Urban Mbarara, Uganda by Benedict Twinomugisha, Abdon Marius Birungi

    Published 2024-01-01
    “…There is a need to establish evidence-based strategies to inform policy on prevention of childhood overweight/obesity.…”
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    Article
  3. 17743

    TRAF2 and RIPK1 redundantly mediate classical NFκB signaling by TNFR1 and CD95-type death receptors by Jennifer Wagner, David Vredevoogd, Xin Yu, Dong Lu, Daniel S. Peeper, Heike M. Hermanns, Jin Wang, Harald Wajant, Daniela Siegmund

    Published 2025-01-01
    “…Based on our findings, two distinguishable types of TNFR1-interacting complexes promote TNF-induced NFκB signaling: First, a TRADD-TRAF2/cIAP utilizing complex Ia which becomes evident in RIPK1-deficient cells. Second, a non-modified RIPK1 utilizing complex Ib which acts in TRADD- or TRAF2-deficient cells. …”
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  4. 17744

    Thyroid function during COVID-19 and post-COVID complications in adults: a systematic review by Anisha Panesar, Palma Gharanei, Natasha Khovanova, Lawrence Young, Dimitris Grammatopoulos, Dimitris Grammatopoulos

    Published 2025-02-01
    “…COVID-19 primarily targets the respiratory system but also affects multiple organ systems, including the endocrine system. Emerging evidence suggests interactions between thyroid function, the acute phase of COVID-19, and the prolonged symptoms known as post-COVID sequalae or long COVID. …”
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  5. 17745

    A Comparison of Resting Scapular Posture and the Davies Closed Kinetic Chain Upper Extremity Stability Test by John D Heick, Jenna Haggerty, Robert C Manske

    Published 2021-06-01
    “…Additional studies are required to identify the usefulness of the Kibler scapular position classification. # LEVEL OF EVIDENCE 2b: Individual Cohort Study…”
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  6. 17746

    Genetic diversity and transmission pattern of multidrug-resistant tuberculosis based on whole-genome sequencing in Wuhan, China by Liqing Wei, Jun Chen, Zhen Deng, Zefang Zhang, Zhengbin Zhang, Qionghong Duan

    Published 2025-01-01
    “…The clustering rates between L4 and L2 strains were not significantly different (χ2 = 0.0017, p > 0.05).ConclusionThe genetic diversity of MDR-TB in Wuhan demonstrates unique characteristics, with evidence of localized transmission. These findings highlight the urgent need to strengthen measures to detect early cases of MDR-TB and control transmission of MDR-TB in the region.…”
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  7. 17747
  8. 17748

    Les aqueducs romains de Lyon et d’ailleurs : nouveaux repères by Aldo Borlenghi, Catherine Coquidé

    Published 2023-12-01
    “…Numerous clues can be used in chasing down a chronology, but uncertainty is often the rule and multiple pieces of evidence have to intersect in order to arrive at plausible conclusions.Finally, bringing water into the city centre is the ultimate purpose. …”
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  9. 17749

    An analytical cross-sectional study on optimal (timely or cumulative age-appropriate) routine childhood immunization coverage in the communities of Ebonyi state, Nigeria by Ugwu I. Omale, Cordis O. Ikegwuonu, Glory E. Nkwo, Chimaobi C. Iwegbulam, Louisa C. Ekwuazi, Chidinma I. Amuzie, Richard L. Ewah

    Published 2025-01-01
    “…Other predictors were having a mother who completed secondary or higher education, delivery at a health facility, decrease in the age of the husband of the mother, decrease in the birth order of the child, and urban/semi-urban residence. The evidence calls for policy actions and interventions to increase optimal routine childhood immunization coverage, and indicate specific factors to be considered, in the efforts to tackle the recurring outbreaks of VPDs.…”
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  10. 17750

    Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

    Published 2025-02-01
    “…Abstract Purpose Emerging evidences have indicated a role of the complement system in the pathogenesis of diabetic nephropathy (DN). …”
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  11. 17751
  12. 17752

    Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

    Published 2024-11-01
    “…This still represents a significant societal burden and these findings may help inform public health initiatives to encourage prevention and evidence‐based interventional strategies and ultimately, improve the quality of life for those suffering with SP in Wales.…”
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  13. 17753

    FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis by Yu Cheng, Yang Jiao, Wan Wei, Mengjia Kou, Yaodong Cai, Yang Li, Hao Li, Tonghua Liu

    Published 2025-02-01
    “…The use of 3-TYP further confirmed FBR2’s intervention in ferroptosis and cellular senescence through the SIRT3/p53 pathway.ConclusionFBR2 shows therapeutic potential in a BLM-induced pulmonary fibrosis mouse model, with its effects mediated through modulation of the ferroptosis pathway via the SIRT3/p53 mechanism. This study provides novel evidence for the targeted treatment of IPF and offers further insights into its pathogenesis.…”
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  14. 17754

    Reliability and Validity of the ActivForce Digital Dynamometer in Assessing Shoulder Muscle Force across Different User Experience Levels by Christos Karagiannopoulos, Sean Griech, Brian Leggin

    Published 2022-06-01
    “…Its low-cost and electronic accessibility features may promote better compliance for clinicians using dynamometry to objectively assess and store muscle force data in a cost-effective manner. # Level of Evidence 3…”
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  15. 17755

    Effects of virtual reality technology on early mobility in critically ill adult patients: a systematic review and meta-analysis by Yansha He, Yansha He, Qin Yang, Xiaoxia Dai, Tian Chen, Huan Wu, Kunjie Li, Shiqiong Zhu, Yanlin Liu, Hua Lei

    Published 2025-02-01
    “…However, the effect of enhancing the functional independence of limbs is not yet evident and still needs to be confirmed by high-quality, multicenter, and large-sample clinical trials.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/ Prospero register No.: CRD42024546409.…”
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  16. 17756

    Muscle Activity and Kinematics During Three Hamstring Strengthening Exercises Compared to Sprinting: A Cross-Sectional Study. by Adelso Jorge, Eric Lichtenstein, Oliver Faude, Ralf Roth

    Published 2024-05-01
    “…All examined exercises demonstrated their peak activity at short hamstring muscle length. # Level of evidence 3b…”
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  17. 17757

    Nicotine-induced CHRNA5 activation modulates CES1 expression, impacting head and neck squamous cell carcinoma recurrence and metastasis via MEK/ERK pathway by Chen Feng, Wei Mao, Chenyang Yuan, Pin Dong, Yuying Liu

    Published 2024-10-01
    “…Nicotine exposure activates CHRNA5, regulating CES1 expression via the MEK/ERK pathway, contributing to the recurrence and metastasis of head and neck squamous carcinoma.…”
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  18. 17758

    Causal Effects of Sleep Traits on Angina Pectoris: Mediation by Cardiovascular Risk Factors by Zeng C, Ke Y, Li H, Zhang C, Chen J, Chen M

    Published 2025-02-01
    “…Getting up in the morning reduced the risk of SAP, while longer sleep duration lowered the risk of SAP and UAP. More evidences are required to clarify the roles of sleep traits and risk factors in AP.Keywords: sleep traits, angina pectoris, hypertension, Mendelian randomization, mediation…”
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  19. 17759

    Diagnostic performance of CT for extrarenal fat invasion in renal cell carcinoma: a meta-analysis and systematic review by Junchao Ma, Enyu Yuan, Shijian Feng, Jin Yao, Chunlei He, Yuntian Chen, Bin Song

    Published 2025-01-01
    “…Abstract Objectives Renal cell carcinoma (RCC) with extrarenal fat (perinephric or renal sinus fat) invasion is the main evidence for the T3a stage. Currently, computed tomography (CT) is still the primary modality for staging RCC. …”
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  20. 17760

    Risk Factors for Stress Fractures in Female Runners: Results of a Survey by Therese E Johnston, Allison E Jakavick, Caroline A Mancuso, Kathleen C McGee, Lily Wei, Morgan L Wright, Jeremy Close, Ayako Shimada, Benjamin E Leiby

    Published 2021-02-01
    “…Prospective studies are warranted to infer a cause and effect relationship amongst these variables and stress fracture risk. # Level of Evidence Level IV…”
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