Status of cerebrovascular autoregulation relates to outcome in severe paediatric head injury: STARSHIP, a prospective multicentre validation studyResearch in context by Shruti Agrawal, Claudia Smith, Stefan Y. Bogli, Michal M. Placek, Manuel Cabeleira, Deborah White, Esther Daubney, Adam Young, Erta Beqiri, Riaz Kayani, Diarmuid O'Donnell, Nazima Pathan, Suzanna Watson, Anna Maw, Matthew Ganrett, Hari Krishan Kanthimathianathan, Harish Bangalore, Santosh Sundararajan, Gayathri Subramanian, Dusan Raffaj, Avishay Sarfatti, Simona Lampareillo, Anton Mayer, Oliver Ross, Marek Czosnyka, Peter J. Hutchinson, Peter Smielewski, Carly Tooke, Caroline Payne, Holly Belfield, Amisha Mistry, Collette Spencer, Claire Jennings, Lara Bunni, Laura Anderson, Emily Morgan, Melanie James, Rebecca Beckley, Tahnima Khatun, Hafiza Khatun, Olivia Nugent, Richard Aldridge, Ruth Morgan, Julie Morcombe, Martin Quinton, Catherine Postlethwaite, Jenny Pond, Jessica Cutler, Caitlin Oxford

“…This provides additional evidence for the potential use of PRx for individualizing prognosis and treatment and pave way for further research in pTBI with the created database. …”
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Amphetamine use as a predictor of cardiovascular and cerebrovascular mortality and morbidity: a longitudinal cohort study of criminal justice clients by Ada Åhman, Jonas Berge, Anders Håkansson

“…Amphetamine was not significantly associated with cardiovascular or cerebrovascular events, compared to the main drug heroin or polysubstance use.ConclusionIn this study on substance-using criminal justice clients, while the highest incidence rates of both cardiovascular and cerebrovascular events were found among amphetamine-using individuals, the study did not provide evidence of an independent association. The study highlights the need to take co-factors into account, such as comorbidities and socio-economic factors. …”
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Socioeconomic factors and sex effects of postpartum maternal depression on offspring internalizing symptoms: a systematic review and meta-analysis by Yang Geng, Wenlan Liu, Zhiying Yu, Hui Zhang, Yun Li, Weihua Zhao

“…ROBINS-E tool was used to rate the quality of evidence. Results Twenty-eight studies were eligible between 1997 and 2023, including 24,022 mother–child dyads. …”
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IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3 by Huiyue Dong, Huiyue Dong, Ling Zhu, Ling Zhu, Jingjing Sun, Jingjing Sun, Qiuyan Chen, Qiuyan Chen, Pengyang Liu, Pengyang Liu, Wei Zhang, Huajing Zeng, Rong Lin, Rong Lin, Zongyang Yu, Zongyang Yu, Jun Lu, Jun Lu, Jun Lu, Jun Lu

“…Meanwhile, compared to the groups treated with either IFNβ or RSL3 alone, the combination treatment of IFNβ and RSL3 significantly inhibited the growth of HT1080 three-dimensional (3D) spheroids and tumor in a mouse xenograft model.ConclusionsOur work reveals a role for IFNβ in promoting ferroptosis and provides evidence that IFNβ could be used with RSL3 to increase cytotoxic effects in tumor cells.…”
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Evaluation and comparison of portfolios formed by strategies through PE, PEG, PERG-SD, and PERG-Beta in the Tehran stock exchange by Hossein Eslami, Seyed Mohammad Moshashaei, Farzad Rahimzadeh

“…Another goal of this research is to determine whether the strategies above can be superior to the TEDPIX index in the long term.Methodology: Our evidence includes 362 companies listed on the Tehran Stock Exchange from 2016 to 2023, and 110 have been selected as a research sample. …”
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Sonic hedgehog restrains the ubiquitin-dependent degradation of SP1 to inhibit neuronal/glial senescence associated phenotypes in chemotherapy-induced peripheral neuropathy via the TRIM25-CXCL13 axis by Ying Zou, Shu Wu, Qian Hu, Haoxian Zhou, Yuanlong Ge, Zhenyu Ju, Shengkang Luo

“…Conclusion: These findings provide evidence for the role of PTX-induced senescence in DRG sensory neurons and Schwann cells, suggesting that Shh could be a potential therapeutic target for CIPN.…”
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The Novel Histological Prostatic Inflammation Score Helps Defining the Association Between Stromal and Glandular Inflammation with the Risk of Prostate Cancer at Prostate Biopsy by Ugo Giovanni Falagario, Francesca Sanguedolce, Angelo Cormio, Antonella Ninivaggi, Marco Finati, Francesco Guzzi, Gian Maria Busetto, Carlo Bettocchi, Daniele Castellani, Giuseppe Carrieri, Luigi Cormio

“…<b>Background:</b> There is emerging evidence of an inverse association between prostatic inflammation (PI) and prostate cancer (PCa) diagnosis and outcome. …”
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PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways by Xue He⁺, Yanan Cui⁺, Tiao Li, Lijuan Luo, Zihang Zeng, Yiming Ma, Yan Chen

“…Conclusions PU.1 alleviates the inhibitory effects of CSE on EPC function and lunghoming via activating the canonical Wnt/β-catenin pathway and CXCL12/CXCR4 axis. …”
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Workforce outcomes among substance use peer supports and their contextual determinants: A scoping review protocol. by Justin S Bell, Tina Griffin, Sierra Castedo de Martell, Emma Sophia Kay, Mary Hawk, Michelle Hudson, Bradley Ray, Dennis P Watson

“…<h4>Objective</h4>This scoping review protocol aims to describe a proposed effort to review the nature and extent of research evidence on peer workforce outcomes and how these outcomes might differ across service settings. …”
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1990–2041 Global burden of Burkitt lymphoma with 20 years forecast: A systematic analysis using the global burden disease of study of 2021 by Chengyun Dou, Yidan Sang, Hongbo Zhu, Chuangjie Cao

“…High body-mass indexes contribution to Burkitt lymphoma is evident in the disability-adjusted life-years, with the United States and the United Kingdom recording 0.06 and 0.05, respectively. …”
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The Quality of Functional Movements and the Back Squat in Amateur and Professional Bodybuilders by VERONIKA ILJINAITĖ, LAIMONAS ŠIUPŠINSKAS, KRISTINA BERŠKIENĖ

“…Greater experience in bodybuilding is associated with the compliance with several BSA criteria: trunk position, frontal knee alignment, tibial translation angle, foot position in all three back squat variations with different external loads, and descent with the training weight. # Level of Evidence 3b…”
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Characteristics and publication status of minimally invasive glaucoma surgery trials registered in ClinicalTrials.gov, 2007–2024: a cross-sectional study by Chuzhi Peng, Hongyan Jia, Jianping Hu, Yonghong Jiao

“…Overcoming the design limitations of trials will be essential for generating more robust evidence to guide clinical practice and policy decisions.…”
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Association between joint exposure to ambient air pollutants and carotid plaque: The mediating role of cardiometabolic risk factors by Yunfei Li, Ze Han, Xiaoyu Zhao, Yueruijing Liu, Zhiyuan Wu, Jinqi Wang, Xia Li, Xiuhua Guo, Lixin Tao

“…Background: Research has shown that exposure to joint air pollution is related to atherosclerosis, but little evidence has been found for carotid plaques. Our objective is to assess the association between exposure to joint air pollutants and carotid plaque and explore the mediating role of cardiometabolic factors in this relationship. …”
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Phytophthora: an ancient, historic, biologically and structurally cohesive and evolutionarily successful generic concept in need of preservation by Clive Brasier, Bruno Scanu, David Cooke, Thomas Jung

“…Abstract The considerable economic and social impact of the oomycete genus Phytophthora is well known. In response to evidence that all downy mildews (DMs) reside phylogenetically within Phytophthora, rendering Phytophthora paraphyletic, a proposal has been made to split the genus into multiple new genera. …”
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Basal ganglia components have distinct computational roles in decision-making dynamics under conflict and uncertainty. by Nadja R Ging-Jehli, James F Cavanagh, Minkyu Ahn, David J Segar, Wael F Asaad, Michael J Frank

“…Theoretical accounts suggest that dynamic regulation of the amount of evidence required to commit to a decision (a dynamic "decision boundary") may be necessary to meet these competing demands. …”
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Development of an Injury Burden Prediction Model in Professional Baseball Pitchers by Garrett Bullock, Charles Thigpen, Gary Collins, Nigel Arden, Thomas Noonan, Michael Kissenberth, Ellen Shanley

“…The inclusion of both modifiable and non-modifiable factors into a comprehensive injury burden model provides the most accurate prediction of days lost in professional pitchers. # Level of Evidence 2…”
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Beverage consumption modifies the risk of type 2 diabetes associated with ambient air pollution exposure by Chaonan Fan, Wenjuan Wang, Wenxue Xiong, Zhiyao Li, Li Ling

“…Background: Evidence on how beverage consumption modifies associations between air pollution (AP) exposure with the type 2 diabetes (T2D) risk remains scarce, which we aimed to investigate in this study. …”
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Pseudovibriamides from Pseudovibrio marine sponge bacteria promote flagellar motility via transcriptional modulation by Yitao Dai, Vitor Lourenzon, Laura P. Ióca, Dua Al-Smadi, Lydia Arnold, Ian McIntire, Roberto G. S. Berlinck, Alessandra S. Eustáquio

“…Thus, this work gives insights into pseudovibriamide biosynthesis and provides evidence that they are signaling molecules relevant to bacterial motility and to other yet-to-be-identified phenotypes.…”
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The effect of cheese intake on osteoarthritis: a Mendelian randomization study by Song Wen, Zehan Huang, Bin Zhang, Yuqing Huang

“…Conclusions Our findings provided compelling genetic evidence of causal inverse associations between cheese intake and various types of OA, including self-reported OA, OA of the hip or knee, knee OA, and hip OA, which may enhance the efficacy of OA prevention by deepening our comprehension of the involved risk factors.…”
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Development and validation of the Information Literacy Measurement Scale (ILMS-34) in Chinese public health practitioners by Hui Li, Ke-Ying Li, Xia-Rong Hu, Xuan Hong, Yan-Ting He, Hua-Wei Xiong, Yi-Li Zhang

“…Abstract Background Public health professionals (PHPs) have increasing information needs to inform evidence-based public health decisions and practice, which requires good information literacy. …”
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