Changes in Intestinal Microbiota Are Associated with Islet Function in a Mouse Model of Dietary Vitamin A Deficiency by Yunting Zhou, Junming Zhou, Yumin Zhang, Jun Tang, Bo Sun, Wei Xu, Xiaohang Wang, Yang Chen, Zilin Sun

“…The underlying mechanisms involved in Vitamin A- (VA-) related changes in glucose metabolic disorders remain unclear. Recent evidence suggests that intestinal microbiota is closely linked to the metabolic syndrome. …”
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A comprehensive scoping review of intergenerational dance programmes for cohorts with a generational gap. by Siobhán O'Reilly, Orfhlaith Ní Bhriain, Sarah Dillon, Amanda M Clifford

“…The aim of this scoping review was to collate and map the available evidence for intergenerational dance.<h4>Methods</h4>This scoping review followed the guidance outlined by the Joanna Briggs Institute. …”
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Solving unknown primary cancer with earlier diagnosis - the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for... by Anna Ugalde, Richard W. Tothill, Stephen Quinn, Hui-Li Wong, Owen Prall, Catherine Mitchell, Nilmini Wickramasinghe, Clare Fedele, Natalie Richards, Elizabeth Todio, Cindy Bryant, Louisa G. Collins, Sarah McLean, Hyun Soo Ko, Tim Akhurst, Christopher Steer, Bo Gao, Mark Wong, Chloe Georgiou, Narayan Karanth, Anna Kuchel, Louise Nott, Shamsudheen Padinharakam, Mark Shackleton, Ian M. Collins, Madhu Singh, Rachel Wong, Zee Wan Wong, Alexis Butler, Tharani Sivakumaran, Penelope Schofield, Linda Mileshkin

“…This research will generate important evidence with scalability for future research at trial completion. …”
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Are We Overlooking Anatomical Contributions to Dynamic Knee Valgus? by Matt Dewald, Madison Andersen, Laura Higgins, Emma Porter, Alex Wickersham

“…Future research should normalize DKV measurements by bony anatomy when addressing DKV and jump performance. # Level of Evidence 2c…”
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Expression pattern of lncRNA H19 in oral squamous cell carcinoma tissues in comparison to normal tissues. A systematic review by Ramya Sekar, Selvaraj Jayaraman, Saranya Varadarajan, Thodur Madapusi Balaji, Vishnupriya Veeraraghavan, Prabhu Shankar Dayasankar, Dharshini Devi J

“…Nevertheless, its expression patterns in OSCC in contrast to healthy tissues remain unclear. The evidence currently available about H19's expression in OSCC is assessed in this review. …”
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Is the Use of Tourniquets More Advantageous than Other Bleeding Control Techniques in Patients with Limb Hemorrhage? A Systematic Review and Meta-Analysis by Roberto Cirocchi, Dominica Prigorschi, Luca Properzi, Matteo Matteucci, Francesca Duro, Giovanni Domenico Tebala, Bruno Cirillo, Paolo Sapienza, Gioia Brachini, Sara Lauricella, Diletta Cassini, Antonia Rizzuto, Andrea Mingoli

“…<i>Background and Objectives:</i> Trauma, particularly uncontrolled bleeding, is a major cause of death. Recent evidence-based guidelines recommend the use of a tourniquet when life-threating limb bleeding cannot be controlled with direct pressure. …”
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Evaluation of the Level of Salivary sHLA-G in Children Aged 3–5 Years with or without Dental Caries by Mansoureh Bijani, Amrollah Mostafazadeh, Mina Motallebnejad, Ali Bijani, Roghiyeh Pourbagher, Samaneh Gharekhani

“…The present study provides some preliminary evidences on relationship between sHLA-G and dental caries in children.…”
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Dynamic Functional Ability in Lacrosse Players in Relation to Development of Sport-Related Onset of Musculoskeletal Pain by Zane Thompson, Joseph G. Wasser, Kevin R. Vincent, Heather K. Vincent

“…Detecting these pertinent biomechanical errors and subsequently developing proper training programs could help prevent lower extremity and low back pain onset. # Level of Evidence III…”
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Effects of a Groin Pain Prevention Program in Male High School Soccer Players: A Cluster-Randomized Controlled Trial by Kazuki Fujisaki, Kiyokazu Akasaka, Takahiro Otsudo, Hiroshi Hattori, Yuki Hasebe, Toby Hall

“… # Conclusion A 16-week program incorporating the CAE in training sessions in high school soccer players reduced the incidence of groin pain and which may be related to injury severity according to time -lost to soccer, however the combination of both the CAE and NHE may be more effective than the CAE alone. # Level of Evidence 2b…”
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Russian Science Foundation grant No. 20-14-00140 supported this study. The authors are thankful to the multi-access Center “Bioinformatics” for the use of computational resources a... by O. V. Vishnevsky, I. V. Chadaeva, E. B. Sharypova, B. M. Khandaev, K. A. Zolotareva, A. V. Kazachek, P. M. Ponomarenko, N. L. Podkolodny, D. A. Rasskazov, E. V. Zemlyanskaya, A. G. Bogomolov, O. A. Podkolodnaya, L. K. Savinkova, M. P. Ponomarenko

“…This topic is becoming increasingly relevant as the allergization of the population grows, being a major challenge for modern medicine. That is why intensive research by breeders is already underway for creating hypoallergenic forms of food plants. …”
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Effectiveness of digital behaviour change interventions for promoting physical activity in adolescents with overweight and obesity: A systematic review and meta-analysis by Puteri Shanaz Jahn Kassim, Noor Azimah Muhammad, Nur Faraheen Abdul Rahman, Sherina Mohd Sidik, Cecilia A. Essau, Shamsul Azhar Shah

“…Digital behaviour change interventions (DBCI) are increasingly used to increase physical activity; however, there is insufficient evidence on their use in promoting physical activity among adolescents with overweight and obesity, including its active components. …”
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The Effect of Concussion History on Lower Extremity Injury Risk in College Athletes: A Systematic Review and Meta-Analysis by Vanessa Ramirez, Ryan McCann, Eric Schussler, Jessica Martinez

“…Clinical assessments throughout the concussion return-to-play protocol may need to be improved in order to detect lingering impairments caused by concussions. # Level of Evidence 1…”
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Rasagiline as Adjunct to Levodopa for Treatment of Parkinson’s Disease: A Systematic Review and Meta-Analysis by Osamu Kano, Hiroshi Tsuda, Ayako Hayashi, Masaki Arai

“…This meta-analysis aimed to provide updated evidence on the efficacy for motor and nonmotor symptoms and the safety of rasagiline/levodopa versus levodopa in patients with Parkinson’s disease experiencing motor fluctuations. …”
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An Interval Throwing Program for Baseball Pitchers Based upon Workload Data by Michael M. Reinold, Brittany Dowling, Glenn S. Fleisig, Leonard C. Macrina, Kevin E. Wilk, John T. Streepy, James R. Andrews

“…The ITP may be used following common injuries or surgeries to the throwing shoulder and elbow, such as Tommy John surgery, while also serving as a basis for future development of shorter duration ITPs. # Level of Evidence 2c…”
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Creep enhancement and sliding in a temperate, hard-bedded alpine glacier by J.-P. Roldán-Blasco, A. Gilbert, L. Piard, F. Gimbert, C. Vincent, O. Gagliardini, A. Togaibekov, A. Togaibekov, A. Walpersdorf, N. Maier

“…Our study provides further evidence that borehole inclinometry, combined with full-Stokes flow modeling, allows for the constraining of both ice rheology and basal friction at scales that cannot be inferred from surface velocity measurements alone.…”
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Emotion regulation-based internet-delivered cognitive behavioural therapy for premenstrual dysphoric disorder: study protocol for a randomised controlled trial in Sweden by Filipa Sampaio, Alkistis Skalkidou, Gerhard Andersson, Cornelia Weise, Johanna M. Hoppe, Maria Kleinstaeuber, Johan Vegelius, Erika Comasco, Maria Gröndal, Elisavet Kaltsouni, Felicia Sundström, Monica Buhrman

“…Thus, non-pharmacological treatments are needed as an alternative or additive treatment strategy. Evidence indicates that cognitive behavioural therapy (CBT) is a promising candidate. …”
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Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats by Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami

“…Human leucocyte antigen (HLA)-B27 is a genetic risk factor for SpA. Recent evidence suggests that the interleukin −17 (IL17) axis strongly contributes to SpA. …”
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Molecular mechanisms and therapeutic strategies of Naegleria fowleri Carter (1970): a review of the fatal brain-eating amoeba by N. Datta

“…Currently, there is no specific or approved treatment for PAM, and the available options are based on empirical evidence or case reports. The survival rate of PAM remains very low, despite the use of multiple drugs and supportive care. …”
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Dysplasia in Ulcerative Colitis by RH Riddell

“…It is assumed that surveillance will reduce the mortality from colorectal cancer, although the evidence that this is happening is very limited. Cancers which are resected but from which the patient survives are an acceptable outcome, although less so in theory, as survival is to a certain extent fortuitous. …”
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Five decades of Abramov glacier dynamics reconstructed with multi-sensor optical remote sensing by E. Mattea, E. Berthier, A. Dehecq, T. Bolch, T. Bolch, A. Bhattacharya, A. Bhattacharya, S. Ghuffar, M. Barandun, M. Hoelzle

“…We also measure the buildup to a third velocity pulsation, with doubling of mean annual velocity since 2011 despite a continued mass loss of <span class="inline-formula">−</span>0.55 <span class="inline-formula">±</span> 0.06 m w.e. yr<span class="inline-formula">⁻¹</span>. The collected evidence indicates that Abramov is a surge-type glacier with a recurrence time of 20–30 years, challenging its representativity for regional mass balance. …”
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