Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time by Anthony A. Fryer, David Holland, Michael Stedman, Christopher J. Duff, Lewis Green, Jonathan Scargill, Fahmy W. F. Hanna, Pensée Wu, R. John Pemberton, Christine Bloor, Adrian H. Heald

“…In general, less variability in testing frequency (more consistent monitoring) was associated with better diabetes control. This was most evident with moderately raised baseline HbA1c levels (7.0–9.0% (54–75 mmol/mol)). …”
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Intramedullary Fixation for Metacarpal Fractures: A Multi-Institutional Prospective Outcomes Study by Michael B. Gehring, MD, Brandon Wolfe, BA, Riley Kahan, BS, Stephanie D. Malliaris, MD, Kia M. Washington, MD, Matthew D. Folchert, MD, Kyros Ipaktchi, MD, Mark A. Greyson, MD, Alexander Lauder, MD, Matthew L. Iorio, MD

“…Type of study/level of evidence: Therapeutic IV.…”
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Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins by Anna-Sophia Hartke, Cara S. Schreiber, Kristina Lau, Ivo Wiesweg, Inken Waltl, Ulrich Kalinke, Franziska Richter, Christopher Käufer

“…Increasing evidence points to infectious diseases as contributor to the pathogenesis of neurodegeneration in Parkinson's disease (PD), probably driven by a peripheral and CNS inflammatory response together with alpha-synuclein (aSyn) pathology. …”
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Associations of blood-based biomarkers of neurodegenerative diseases with mortality, cardio- and cerebrovascular events in persons with chronic coronary syndrome by Valerie Lohner, Laura Perna, Ben Schöttker, Robert Perneczky, Hermann Brenner, Ute Mons

“…Background: In light of growing evidence highlighting interactions between cardiac and brain health, we investigated associations of biomarkers of neurodegenerative diseases with adverse outcomes (all-cause and cardiovascular mortality, major cardiovascular events, and stroke) in persons with chronic coronary syndrome (CCS). …”
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DNA hypomethylation-mediated upregulation of GADD45B facilitates airway inflammation and epithelial cell senescence in COPD by Yuan Zhan, Qian Huang, Zhesong Deng, Shanshan Chen, Ruonan Yang, Jiaheng Zhang, Yating Zhang, Maocuo Peng, Jixing Wu, Yiya Gu, Zhilin Zeng, Jungang Xie

“…Introduction: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease typically characterized by chronic airway inflammation, with emerging evidence highlighting the driving role of cellular senescence-related lung aging. …”
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Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations by Ayat Kadhi, Ayat Kadhi, Ayat Kadhi, Edward Eid, Michel J. Massaad, Inaam El-Rassy, Dana Maria Khoury, Yutaka Shimomura, Nelly Rubeiz, Mazen Kurban, Mazen Kurban, Mazen Kurban, Georges Nemer, Georges Nemer

“…Despite the truncation, our investigations revealed that this variant produces a fully functional IL17RA protein. This was evident from the presence of IL17RA in the patient’s peripheral blood mononuclear cells (PBMCs) and the ability of the mutant IL17RA to dimerize with both wild-type protein and its partners IL17RC and IL17RD. …”
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The Role of Cardiac Resynchronization Therapy in Heart Failure: A Narrative Review by Olivier Uwishema, Ece Karabulut, Dalal Sheikhah, Burhan Kantawala, Misgana Gallo, Fatima Soufan, Magda Wojtara

“…Methods An extensive review of the literature was conducted with evidence from several databases like Medline, PubMed Central, and Embase. …”
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Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOk... by Narayanaswamy Venketasubramanian, Deidre Anne De Silva, Christopher P L H Chen, Cyrus G Escabillas, John Harold Hiyadan, Johnny K Lokin, Romulo U Esagunde, Joel M Advincula, Christian Oliver C Co, Maria Epifania V Collantes, Annabelle Y Lao, Yeow-Hoay Koh, Carol Huilian Tham

“…The results of this study will provide objective level B evidence on the efficacy of MLC1501 on long-term recovery and safety of 24 weeks of treatment among patients with IS.Trial registration number NCT05289947.…”
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World-wide survey on the treatment of peripheral vestibular disorders by Michael Strupp, Michael Strupp, Nils Lucca Kern, Nils Lucca Kern, Göran Laurell, Louisa Lehner, Eva Grill, Eva Grill, Ralf Strobl, Ralf Strobl

“…This study shows in particular that certain drugs are often used despite low or very low evidence. Namely in AUVP, MD and VP well-designed controlled trials with clinically meaningful endpoints are needed.…”
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Blockade of Erythropoietin-Producing Human Hepatocellular Carcinoma Receptor B1 in Spinal Dorsal Horn Alleviates Visceral Pain in Rats by Chen-Li Sun, Cheng-Wen Li, Nong He, Yuan-Zhang Tang, Xiu-Liang Li, Fu-Shan Xue, Jia-Xiang Ni

“…The spinal expressions of EphB1, p-EphB1, ephrinB2, and p-ephrinB2 were significantly increased in the TNBS group compared with the control group, but visceral hyperalgesia and elevation of spinal EphB1 and p-EphB1 expressions were evidently alleviated by intrathecal administration of EphB2-Fc in the TNBS + EphB2-Fc group. …”
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Age‐related longitudinal change in cardiac structure and function in adults at increased cardiovascular risk by Fei Fei Gong, Jennifer M. Coller, Michele McGrady, Umberto Boffa, Louise Shiel, Danny Liew, Simon Stewart, Alice J. Owen, Henry Krum, Christopher M. Reid, David L. Prior, Duncan J. Campbell

“…Conclusions Whereas the increase in LVMI with age was explained by CVD risk factors alone, age, together with risk factors, independently predicted longitudinal change in all other echocardiographic parameters, providing evidence for age‐specific mechanisms of change in cardiac structure and function as people age. …”
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Empowering Nursing Practices: Enhancing Patient Care Through Knowledge, Attitude and Practice Towards Urinary Catheterisation in Taicang City by Lihong Zhang, Hong Zhang, Yaxuan Wang, Hui Li, Ting Liu, Jingjing Qian, Chi Wang

“…The findings would provide evidence for policymakers to develop targeted educational intervention to improve nurses’ practice and might improve the outcomes of patients. …”
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Identifying Conservative Interventions for Individuals with Subacromial Pain Syndrome Prior to Undergoing a Subacromial Decompression: A Scoping Review by Joseph A Signorino, Aubrey G. Thompson, Benjamin R Hando, Jodi L Young

“…Many questions regarding optimal conservative management for SAPS persists. # Level of Evidence n/a…”
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Stochastic population models to identify optimal and cost‐effective harvest strategies for feral pig eradication by Peter W. Hamnett, Frédérik Saltré, Brad Page, Myall Tarran, Matt Korcz, Kate Fielder, Lindell Andrews, Corey J. A. Bradshaw

“…Although many feral pig eradications have been attempted, management decisions are often led by practitioner experience rather than empirical evidence. Few interventions have been guided by population models to identify harvest intensity necessary to achieve eradication within a specified time frame, nor have they applied data on control effort and costs to evaluate the relative cost‐effectiveness of proposed control strategies. …”
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Grid-Scale Battery Systems for VAR Support in Con Edison Distribution Substations via Bi-Directional Smart Inverters by Mohamed K. Kamaludeen, Yusef Esa, Kirn Zafar, Elihu Nyemah, Ahmed Ali A. Mohamed, Tamer Ibrahim, Simon Odie

“…According to the literature review carried out and presented in this paper, it is evident that reactive power control for DER applications and grid have been examined in various studies. …”
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Interactive effects of atmospheric oxidising pollutants and heat waves on the risk of residential mortality by Nan Ren, Huimin Huang, Baoying Liu, Chuancheng Wu, Jianjun Xiang, Quan Zhou, Shuling Kang, Xiaoyang Zhang, Yu Jiang

“…Conclusions Overall, we found some evidence suggesting that heat waves increase the impact of oxidising atmospheric pollutants on residential mortality to some extent.…”
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Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol by Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Vivian Wing Yan Lee, Kai Chow Choi, Alexander Yuk Lun Lau, David R Thompson, Eddie Chi Fai Kwok

“…Systematic reviews have yielded inconclusive evidence regarding the effectiveness of different interventions intended to support stroke survivors’ social participation. …”
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Professional Barriers in Energy Efficiency Retrofits—A Solution Based on Information Flow Modeling by Xilong Liao, Chun Wang, Baiyi Li, Baizhan Li, Chenqiu Du

“…The multifaceted nature of systems involved in building retrofits results in a complex project, with barriers in both retrofit design and construction becoming increasingly evident. This research comprehensively assesses the common barriers in building retrofits and investigates the potential for integrating energy-efficient retrofits with information flow modeling from an interdisciplinary perspective. …”
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Avian influenza overview September–December 2024 by European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian Influenza, Leonidas Alexakis, Hubert Buczkowski, Mariette Ducatez, Alice Fusaro, Jose L. Gonzales, Thijs Kuiken, Karl Ståhl, Christoph Staubach, Olov Svartström, Calogero Terregino, Katriina Willgert, Miguel Melo, Lisa Kohnle

“…Human infections with avian influenza viruses remain rare and no evidence of human‐to‐human transmission has been documented in the reporting period. …”
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Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women und... by Christopher Oldmeadow, Mitch J Duncan, Penny Reeves, Priscilla Viana da Silva, Rebecca Wyse, Helen Moore, Alison Zucca, Sancha Robinson, Stephen Ridley Smith, Emma Sansalone, Owen Morris, Rebecca Chenery, Lara Riley, Anna Palazzi-Parsons

“…The DHI incorporates the following evidence-based behaviour change strategies: education, self-monitoring and feedback and prompts and cues. …”
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