Predictive Factors of Response to Biological Disease Modifying Antirheumatic Drugs: Towards Personalized Medicine by Claire I. Daïen, Jacques Morel

“…Many therapies are now available for patients with rheumatoid arthritis (RA) who have an inadequate response to methotrexate including tumor necrosis factor inhibitors, abatacept, tocilizumab, and rituximab. …”
Get full text

Incidental Diagnostic and Treatment of a Suppurative Appendicitis at Colonoscopy by Mohammed Amine Benatta

“…We herein report a patient with acute appendicitis who was diagnosed by colonoscopy: a 54-year-old woman with normal physical examination and laboratory results within normal limits. …”
Get full text

Aversion for Avulsion: A Case of Delayed Diagnosis of Traumatic Tricuspid Rupture by Wendy K. Bernstein, Nicholas Goehner

“…However, the incidence of this injury is rising due to the improved initial treatment of complex trauma patients as well as enhanced early detection methods through the use of cardiac ultrasound. We report the case of an otherwise healthy 42 year old male who sustained significant blunt force trauma after a single motor vehicle accident. …”
Get full text

Bihemispheric Posterior Inferior Cerebellar Artery Occurring with an Azygos Anterior Cerebral Artery: Case Study by Jamie Toms, Rishi Wadhwa, Sudheer Ambekar, Hugo Cuellar

“…Variations in intracranial vasculature are well known. We report a rare anatomic variation in a patient who underwent cerebral angiography for suspected intracranial aneurysm. …”
Get full text

Diabetic Myonecrosis: Uncommon Complications in Common Diseases by Sisira Sran, Manpreet Sran, Nicole Ferguson, Prachi Anand

“…We report a case of sudden thigh pain from spontaneous quadriceps necrosis, also known as diabetic myonecrosis, in a 28-year-old patient with poorly controlled diabetes mellitus. …”
Get full text

Cladophialophora bantiana Brain Abscess in an Immunocompetent Patient by Sanjay G. Revankar

“…A case involving a 79-year-old immunocompetent woman who presented with left-sided weakness and a ring-enhancing brain lesion is reported. …”
Get full text

Intrathecal Trastuzumab Treatment of the Neoplastic Meningitis due to Breast Cancer: A Case Report and Review of the Literature by Cristina Dumitrescu, Dominique Lossignol

“…We report the case of a 65-year-old woman, diagnosed with a breast cancer human epidermal growth factor receptor (HER2) previously negative, who developed leptomeningeal carcinomatosis and was treated with intrathecal (IT) trastuzumab (TST). …”
Get full text

Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease by Betül Ünal, Cumhur İbrahim Başsorgun, Sinem Çil Gönülcü, Aslı Uçar, Fatih Çelik, Gülsüm Özlem Elpek

“…Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. …”
Get full text

Cutaneous Basal Cell Carcinoma with Bone Metastases: An Orthopaedic Case Report by Brianna R. Fram, John Strony, Geetha Jagannathan, Scot A. Brown

“…Though metastatic BCC (mBCC) is uncommon, the literature demonstrates a 0.0028%-0.55% rate of metastasis. We report on a patient treated at our institution who was found to have mBCC with osseous metastases. …”
Get full text

Invasive Heart Rate Control as a Salvage Therapy in Amiodarone-induced Thyroid Storm by Emin Evren OZCAN, Mustafa DOGDUS, Resit Yigit YILANCIOGLU, Suleyman Cem ADIYAMAN, Oguzhan Ekrem TURAN

“…This association may put both AF and thyrotoxicosis treatment into a vicious circle, leading to AI cardiomyopathy. Herein, we aimed to present atrioventricular node ablation as a salvage therapy in a patient with AIT who had AF-causing hemodynamic impairment, resistance to medical therapy, and cardioversion.…”
Get full text

Youth Mentoring: Involving College Students by Emily Rickerson, Muthusami Kumaran, Kate Fogarty

“… Today’s youth are facing a number of troubling issues including substance abuse, family disturbances, bullying, low morale resulting in low academic achievement, dropping out of school, and more. Having someone who cares about youth, to talk to them about the issues they face and mentoring them, can be a positive factor for all involved. …”
Get full text

A Few Misconceptions about Cultural Evolution by O’Brien Michael J.

“…Despite a growing number of social scientists who view the evolution of culture as a Darwinian process, research in the field at large is still rooted in the orthogenetic, progressive models of cultural evolution that were popularized in the nineteenth century and brought back in a new form in the mid-twentieth century. …”
Get full text

A Message to Our 2024 Peer Reviewers: Thank You by Advocate Aurora Research Institute

“…Like all peer-reviewed journals, we rely heavily on our diverse pool of academic and clinical reviewers who generously volunteer their time to help rigorously gatekeep original manuscript submissions to the Journal of Patient-Centered Research and Reviews (JPCRR). …”
Get full text

Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn by Farooq Shahzad, Ava G. Chappell, Chad A. Purnell, Monica Aldulescu, Sarah Chamlin

“…The differential diagnosis of a congenital cutaneous vascular-appearing mass in a newborn is broad and includes both benign and malignant tumors. We report the case of a newborn who presented with an erythematous exophytic skin nodule on the right upper leg. …”
Get full text

Rectal Adenocarcinoma With Pagetoid Spread: A Novel Entity by Lefika Bathobakae, Pasha Shenasan, Aakash Trivedi, Ruhin Yuridullah, Sohail Qayyum, Abraham El-Sedfy

“…It is often misdiagnosed as eczema, leukoplakia, squamous cell carcinoma, Bowen’s disease, lichen planus, or condylomata acuminata. We report a case of a 63-year-old male who presented to the emergency room (ER) for evaluation of an anal mass that had persisted over 6 months. …”
Get full text

Ensaio sobre a natureza humana: uma reflexão a partir de Abraham Maslow by Jonas Muriel Backendorf

“…This paper presents some thoughts about who we are as humans, a task that fits in the field of moral psycology, specifically in the areas which aims understanding and defineing more broadly the moral subject or agent. …”
Get full text

Severe Hypercalcemia and Acute Renal Failure: An Unusual Presentation of Sarcoidosis by Rudruidee Karnchanasorn, Molly Sarikonda, Saleh Aldasouqi, Ved V. Gossain

“…Acute renal failure, although described, is also a rare presentation of patients with sarcoidosis. We describe two patients with sarcoidosis, who presented with severe hypercalcemia and worsening renal function. …”
Get full text

Pancreatic Hydatid Cyst Causing Acute Pancreatitis: A Case Report and Literature Review by Bayan Alsaid, Maryam Alhimyar, Fadi Rayya

“…Primary pancreatic hydatid cyst is in unusual location and rarely causes acute pancreatitis. In this paper, we report a case of a 34-year-old man who admitted with recurrent acute pancreatitis. …”
Get full text

Candida dubliniensis breast implant infection in a lung transplant recipient by Ashley Barnes, MD, Kristen Broderick, MD, Errol Bush, MD, Jonathan Orens, MD, Melanie Marashly, CRNP, Shmuel Shoham, MD, Robin Avery, MD

“…This report details the case of a lung transplant recipient with a remote history of breast cancer and breast reconstruction with implants, who received lengthy antifungal therapy for a post-transplant donor-transmitted Candida dubliniensis empyema. …”
Get full text

Undiagnosed HIV Presenting with Lymphoid Interstitial Pneumonitis by Jason J. Rizqallah, Christopher T. Shah, Oladoyin Oluwole, John N. Sheagren

“…Undiagnosed or untreated human immunodeficiency virus infection can lead to devastating complications. We present a case of a 41-year-old woman who was found to have HIV-related lymphoid interstitial pneumonitis. …”
Get full text