HER-SAFE study design: an open-label, randomised controlled trial to investigate the safety of withdrawal of pharmacological treatment for recovered HER2-targeted therapy-related c... by Robin Chung, James C Moon, Alexander R Lyon, Charlotte H Manisty, Muhummad Sohaib Nazir, Malcolm Walker, Peter Kellman, Benjamin Dowsing, Daniel Chen, Jessica Artico, Mark Westwood, Hakim-Moulay Dehbi, Rebecca Roylance, Tom Crake, Peter Schmid, Arjun Ghosh, Maria Sol Andres, Joanna Pedra, Orla Worn

“…The study will recruit 90 participants who will undergo serial clinical assessment over 12 months with advanced cardiovascular imaging (CMR scans with automated analysis at baseline, 6 and 12 months), cardiac biomarker measurement (six time points over 12 months), plus complete heart failure QoL and medication disutility questionnaires. …”
Get full text

The appearance of scalp high‐frequency oscillations is associated with poor seizure control in pediatric epilepsy patients by Keisuke Maeda, Nami Hosoda, Himari Tsuboi, Honoka Naito, Chiaki Kudo, Junichi Fukumoto, Shiho Fujita, Naohiro Ichino, Keisuke Osakabe, Keiko Sugimoto, Shunta Yamaguchi, Naoko Ishihara

“…Plain Language Summary This study analyzed scalp high‐frequency oscillations and spikes in pediatric patients with various types of epilepsy who were being treated using ASMs. The results showed that an increased risk of scalp HFO appearance was observed in patients with poor seizure control compared to those with good seizure control. …”
Get full text

Perancangan dan Implementasi Sistem Informasi Deteksi Kesesuaian Pemanfaatan Ruang Berbasis Web dengan Fitur Geo-Intersection Pada POSTGIS by Issa Arwani, Widhy Hayuhardhika Nugraha Putra, Ghazian Hamdi, Tsania Dzulkarnain

“…The public and investors who want to access RSPA information directly go to the DPUPR-Perkim office. …”
Get full text

Association between sperm motility in thawed semen and pregnancy rate in Mediterranean buffaloes by Armando Quintero-Moreno, Carla Osorio Meléndez, Héctor Nava-Trujillo, Jorge Rubio Guillén, Juan Carlos Gutiérrez-Añez, Adriana Camacho de Gutiérrez

“…The results show that the buffalo bulls with high fertility (A and B) presented in their ejaculates sperm with the best VAP (Z: 14.6% and Y: 15.84%) and less quantity of immobile sperm (W: 7.14% and V: 1.63%) (P<0.01). …”
Get full text

Current trends of unicompartmental knee arthroplasty (UKA): choosing between robotic-assisted and conventional surgeries and timing of procedures by Kelvin S. C. Cheung, Kai Chun Augustine Chan, Amy Cheung, Ping Keung Chan, Michelle Hilda Luk, Kwong Yuen Chiu, Henry Fu

“…Abstract Background With robotic advancements in UKA technology, we sought to explore if robotic-assisted UKA could translate to clinical benefits such as reduced hospital stays and lowered emergency readmissions. …”
Get full text

Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Methods The present study utilized a three-year longitudinal cohort design, with data from the China Health and Retirement Longitudinal Study (CHARLS). 4,869 participants aged 60–97 years from CHARLS wave 2015 and 2018 who were cognitively and physically healthy were included in analysis. …”
Get full text

Corticosteroid use beyond 1-year post heart transplantation is associated with worse outcomes: A contemporary analysis of the ISHLT registry by Abhishek Jaiswal, MD, William L. Baker, Pharm.D, Ashwin Pillai, MD, Michelle Kittleson, MD, PhD, Balaphanidhar Mogga, MD, Zeina Jedeon, MD, Caroline Chen, David A. Baran, MD

“…Methods: We included adults who underwent their first heart-only transplant between January 2010 and June 2018. …”
Get full text

Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…Patients with recurrent epithelial ovarian cancer who have disease progression either during or within 6 months after completion of platinum-based therapy will be included. …”
Get full text

Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…This study sought to identify differences in the use of ENDS device type based on age and cigarette use status to inform policy about regulating ENDS.Design This was a cross-sectional study.Setting Data was derived from a national survey conducted in 2021 in the USA.Participants Participants include 2369 US youth and adults (13 years or older) who reported past 30-day ENDS use.Outcome measures Past 30-day fairly regular use (i.e., several times a week or more) of ENDS device types, namely cigalikes, disposables, refillable tank/box mods, closed pods, refillable pods and drippers. …”
Get full text

Association of Time in Target Range of Resting Heart Rate With Adverse Clinical Outcomes in Patients With Acute Coronary Syndromes After Percutaneous Coronary Intervention by Jianmei Zheng, Cen Chen, Zhongcai Fan, Qiang Ye, Yi Zhong, Jinsong Li, Hao Huang, Jianping Deng, Jinghong Zhao, Tinglin Xiong, Wenjie Tian, Xuemei Zhang

“…A total of 1455 ACS patients who underwent percutaneous coronary intervention (PCI) and were admitted to 22 hospitals between 2019 and 2022 were enrolled and followed up for 12 months. …”
Get full text

Analisis Keberterimaan Pengguna Taring Dukcapil Menggunakan Metode Technology Acceptance Model (TAM), Delone & Mclean dan Importance Performance Analysis (IPA) by Ayu Nyoman Waisantini Winaya, Komang Setemen, Made WIndu Antara Kesiman

“…Respondents are people who take printed documents at the Dukcapil Service. …”
Get full text

Exploring the impact and mechanisms of behavioral activation on sleep disorders in colorectal cancer: a randomized controlled trial by Anlong Li, Runze Huang, Han Ge, Dajie Liu, Shaochun Liu, Yingxue Jia, Jiaying Chai, Xinyi Zheng, Lijun Liu, Chen Gan, Jian Xu, Ling Cheng, Mingjun Zhang, Huaidong Cheng

“…Behavioral activation (BA), derived from cognitive behavioral therapy (CBT), offers a flexible, simple, and cost-effective alternative. …”
Get full text

The Epidemiological Characteristics of Coronavirus Disease (COVID-19) in Halabja Province/Kurdistan –Iraq by Osama Hamid Shareef, Othman Abdulrahman Mohammed, Dashty Aziz Ghafor, Ari Shareef Ali, Hardi Rafat Baqi, Ali Aziz Ali, Aryan Mahmood Faraj, Syamand Ahmed Qadir, Ali Muhi Aldeen Omar Aljabary

“…Samples were obtained nasopharyngeal using a sterilized swab following WHO guidelines and then the real time PCR (RT-PCR) machine was used for analysis. …”
Get full text

How to build a framework to establish a patient research partner network in rheumatology research: a report of a 2-year implementation project by Maarten de Wit, Oliver Distler, Cosimo Bruni, Anna-Maria Hoffmann-Vold, Muriel Elhai, Rucsandra Dobrota, Adrian Ciurea, Caroline Ospelt, Raphael Micheroli, Dania Diem, Stefan Dudli, Kristina Buerki, Stacey Grealis, Melpomeni Toitou, Silke Ludwig, Chantal Britt, Florian Klett, Isabelle Steeb, Tanja Maletic, Andreas Eisenring, Penelope Jane Timpert-Argust, Eva Camarillo-Retamosa

“…Background Patient research partners (PRPs) are people living with a relevant disease who actively contribute to research. Their contribution is beneficial for any research project. …”
Get full text

Pembrolizumab hybrid dosing is non-inferior to flat dosing in advanced non-small cell lung cancer: a real-world, retrospective bicenter cohort study by Egbert F Smit, Willemijn S M E Theelen, Michiel M Smeenk, Vincent van der Noort, Jeroen M A Hendrikx, Hanieh Abedian Kalkhoran

“…However, clinical efficacy data are lacking.Methods In this retrospective cohort trial, consecutive patients with advanced non-small cell lung cancer (NSCLC) who received ≥1 cycle pembrolizumab±chemotherapy at two tertiary institutions were included. …”
Get full text

Assessment of The Factors Affecting Management of Gender and Sexual Violence Against Women in Rural Communities: A Case Study of Kyanamira Sub County Kabale District. by Tumuheki, Timothy

“…In addition, the bride price meant women's fear of returning to their natal homes without being able to repay the bride price. It also means that women are restricted from legally reporting their spouses to the authorities and bride price practices were found to cause intimidation and isolation of women. …”
Get full text

Sports and Games Union Policy by Kabale University

“…a) Building the physical anatomy of the body for both the young and the old b) Promoting teamwork and discipline given that many sports have strict rules and regulations c) Encouraging patriotism, closer social harmony and the world outlook. …”
Get full text

A Shoemaker Butterfly Prepona laertes (Lepidoptera: Nymphalidae) by James E. Hayden

Get full text

Malignant arrhythmia in a COVID-19 patient with a structurally normal heart by Clare Anne Yoke Kum Fong, Benjamin Wei Liang Tung, Weiqin Lin, Kay Choong See

Get full text

Citrus Pest Quick Guide: Citrus Whitefly by Xavier Martini, Lauren M Diepenbrock, Katie L Ray, Jamie D Burrow

Get full text