Characterization and ameliorative effects of Chenopodium murale hydroethanolic extract against diethylnitrosamine-induced hepato-renal damage and malfunction by Howida S. Abou- Seif, Osama M. Ahmed, Samah A. El-Newary, Marwa E. Shabana, Mahitab I. EL-Kassaby, Ghada M. Elqattan, Hussein G. Sawie

“…C. murale reflecting its ameliorative potential which diminished obviously the DEN-induced elevated hepato-renal levels of IL-1β and TNF-α (immuno- inflammatory indicators), also down regulated Bcl-2, NF-κB, and Nrf-2 (inflammatory mediators). Conclusion These findings proved that C. murale might protect and ameliorate DEN-induced hepato-renal damage through activation of antioxidant and anti-inflammatory systems.…”
Get full text

Ionized and total magnesium levels and health outcomes in patients with type 2 diabetes mellitus by Juhaina Salim Al-Maqbali, Salwa Al Harasi, Qasim Al Mamary, Henrik Falhammar, Ibrahim Al-Zakwani, Mohammed Al Za’abi, Abdullah M. Al Alawi

“…Hypermagnesemia was associated with higher serum creatinine concentrations (p < 0.01) and lower estimated glomerular filtration rate (eGFR) (p = 0.026). An iMg/tMg ratio above 80% was associated with elevated HbA1c levels, while ratios below 60% were associated with diabetic retinopathy and hypertension. …”
Get full text

Bioactive chemical constituents of Curcuma longa L. rhizomes extract inhibit the growth of human hepatoma cell line (HepG2) by Abdel-Lateef Ezzat, Mahmoud Faten, Hammam Olfat, El-Ahwany Eman, El-Wakil Eman, Kandil Sherihan, Abu Taleb Hoda, El-Sayed Mortada, Hassenein Hanaa

Get full text

Public knowledge, attitudes, practices, and barriers to skin cancer screening in the United Arab Emirates. by Anan S Jarab, Walid Al-Qerem, Karem H Alzoubi, Mariam Al Mohammad, Shrouq R Abu Heshmeh, Yazid N Al Hamarneh, Tareq Mukattash, Maher Khdour

“…PLoS ONE…”
Get full text

Paving the way of entrepreneurship for university students: the role of innovativeness, technological adaptability, and self-management, with risk-taking and family support as moderator by Md. Abu Issa Gazi, Anika Tasnim Mim, Abdullah Al Masud, Md. Kazi Hafizur Rahman, Mohammad Bin Amin, Abdul Rahman bin S Senathirajah, Judit Oláh

“…The sampling method used was convenience sampling. We utilized structural equation modeling (SEM) to examine and interpret the data. …”
Get full text

Infantile Extracranial Rhabdoid Tumor of the Scalp by Sura Al Rawabdeh, Deifallah Alsharari, Hayat Khasawneh, Ola M. Al Waqfi, Qamar Yaser Malabeh, Hiathem Abu Alhaija, Raed Mohammad Aljubour, Hamzeh M. Alkhawaldeh

“…This tumor has a grave prognosis. We report to the best of our knowledge the first case of infantile scalp extracranial rhabdoid tumor in a 6-month-old male baby who presented with a right parietal scalp mass since the age of 1 month. …”
Get full text

Investigation of Total Tannin, Phenolic & Flavonoid Content of Araucaria Heterophylla for Antioxidant Source by Ankita Ghosh, Shimanta Paul, Susmita Ghosh, Sadia Akter, Rezwan Ahmed Mahedi, Sadia Afrin, Akayed Hasan, Mohamod Wasaf Hasan, Md Abu Sayeed, Nikolaos Syrmos

“…The present study was conducted to analyze the phytochemical and determine the total flavonoid, tannin, phenolic content of Araucaria Heterophylla leaves extract using two different solvents (methanol and dichloromethane) using UV-Vis spectrophotometric. …”
Get full text

Overview tren penelitian komunikasi pendidikan menggunakan analisis bibliometrik by Arwan Arwan, Miftahuddin Miftahuddin, Alfiah Alfiah, Suhaimi Suhaimi, Abu Anwar, Silawati Silawati, Arbi Arbi, Dramawati Dramawati, Istiqomah Istiqomah, M. Fahli Zatrahadi, Nilma Zola

Get full text

Evaluation of a PCR-based lateral flow device for detecting Aspergillus and Candida species from clinical specimens by Ariff Khalid, Jacinta Santhanam, Mohd Nizam Tzar, Ang-Lim Chua, Sharifah Fadilah Abdul Wahid, Wan Rahiza Wan Mat, Raha Abd Rahman, Petrick Periyasamy

“…To validate the developed system, 203 clinical samples suspected of fungal infection were collected from two hospitals in Kuala Lumpur and tested. Results: The limits of detection of the multiplexed PCR were in the range of 5–100 CFU/mL for fungal spiked human blood samples. …”
Get full text

The association of cytokine levels and postnatal factors with retinopathy of prematurity by Syatirah Abu Yazib, May May Choo, Nurliza Khaliddin, Christine PY Ong, Yao Mun Choo, Azanna Ahmad Kamar, Gopal G Lingam, Tengku A Kamalden

“…Based on follow-up examinations, patients were divided into two groups: No ROP and ROP. The ROP group was further divided into two subgroups: non-vision-threatening ROP (non-VTROP), and vision-threatening ROP (VTROP). …”
Get full text

Relationship between Serum Cytokeratin-18, Control Attenuation Parameter, NAFLD Fibrosis Score, and Liver Steatosis in Nonalcoholic Fatty Liver Disease by Sumitro Kosasih, Wong Zhi Qin, Rafiz Abdul Rani, Nazefah Abd Hamid, Ngiu Chai Soon, Shamsul Azhar Shah, Yazmin Yaakob, Raja Affendi Raja Ali

“…Using CAP, AUROC curves for detection of S≥2 and S≥3 were good (0.76, 0.77, respectively). We also proposed cut-off value of CAP to detect S≥2 and S≥3 to be 263 and 319db/m, respectively, and fragmented CK-18 level to detect S≥2 and S≥3 (194 and 294 U/L, respectively). …”
Get full text

The Diagnostic and Prognostic Value of Kinesin-4A Protein, β-Tubulin Protein, and Exosomes as Non-Invasive Biomarkers in Iraqi Women with Breast Cancer by Samar Hasan Shammar, Hiba Resheed Behayaa, Ahmed F. F. Al-Baaj, Mohammed M. Ewadh, Sura Abd Zaid, Muna M. Ewadh, Mufeed Jalil Ewadh

“…Materials and Methods: This study involved 70 Iraqi women with (BC), who had BC diagnosed for the first time. The study also included a control group (CG) of 70 participants. …”
Get full text

Influence of titanium and gold platelet morphology on heat transfer in biomagnetic third-grade hybrid nanofluid flow through a vertical channel by S. Suneetha, S.R.R. Reddy, Maduru Lakshmi Rupa, T. Mahesh Kumar, Mohammed Jameel, Taoufik Saidani, Lamia Abu El Maati, Dilsora Abduvalieva, M. Ijaz Khan

Get full text

Metabolomics insights into doxorubicin and 5-fluorouracil combination therapy in triple-negative breast cancer: a xenograft mouse model study by Mai M. Hassanein, Mai M. Hassanein, Yousra A. Hagyousif, Yousra A. Hagyousif, Ruba A. Zenati, Ruba A. Zenati, Hamza M. Al-Hroub, Farman Matloob Khan, Ahmad Y. Abuhelwa, Ahmad Y. Abuhelwa, Karem H. Alzoubi, Karem H. Alzoubi, Nelson C. Soares, Nelson C. Soares, Waseem El-Huneidi, Waseem El-Huneidi, Eman Abu-Gharbieh, Eman Abu-Gharbieh, Eman Abu-Gharbieh, Hany Omar, Hany Omar, Dana M. Zaher, Yasser Bustanji, Yasser Bustanji, Yasser Bustanji, Mohammad H. Semreen, Mohammad H. Semreen

Subjects: Get full text

Pt/IrO x enables selective electrochemical C-H chlorination at high current by Bo Wu, Ruihu Lu, Chao Wu, Tenghui Yuan, Bin Liu, Xi Wang, Chenyi Fang, Ziyu Mi, Surani Bin Dolmanan, Weng Weei Tjiu, Mingsheng Zhang, Bingqing Wang, Zainul Aabdin, Sui Zhang, Yi Hou, Bote Zhao, Shibo Xi, Wan Ru Leow, Ziyun Wang, Yanwei Lum

“…However, the large potentials required for C(sp 3)-H bond functionalization and low water solubility of such alkanes make it challenging. Here we discover that a Pt/IrO x electrocatalyst with optimized Cl binding energy enables selective generation of Cl free radicals for C-H chlorination of alkanes. …”
Get full text

Identifying Multiomic Signatures of X‐Linked Retinoschisis‐Derived Retinal Organoids and Mice Harboring Patient‐Specific Mutation Using Spatiotemporal Single‐Cell Transcriptomics... by Yueh Chien, You‐Ren Wu, Chih‐Ying Chen, Yi‐Ping Yang, Lo‐Jei Ching, Bo‐Xuan Wang, Wei‐Chao Chang, I‐Hsun Chiang, Pong Su, Shih‐Yu Chen, Wen‐Chang Lin, I‐Chieh Wang, Tai‐Chi Lin, Shih‐Jen Chen, Shih‐Hwa Chiou

“…Herein, a multimodal approach is demonstrated combining high‐throughput scRNA‐seq and ST to elucidate XLRS‐specific transcriptomic signatures in two XLRS‐like models with retinal splitting phenotypes, including genetically engineered (Rs1emR209C) mice and patient‐derived retinal organoids harboring the same patient‐specific p.R209C mutation. …”
Get full text

β-receptor blocker enhances anti-tumor immunity via inhibiting lactate-induced norepinephrine metabolism of macrophages during malignant pleural effusion by Ru Zhang, Weijia Wang, Aitian Li, Huishang Wang, Xiaoyan Liu, Feifei Fan, Ying Wang, Huanyu Zhang, Jingxia Chang, Yinyin Zhang, Hongmin Wang, Lijun Miao, Bo Huang, Li Yang, Li Yang, Li Yang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang

“…Additionally, lactate triggered phenylalanine/norepinephrine signaling and further induced macrophage immunosuppression in an ERK-depended way. Lastly, in the MPE mouse model, propranolol inhibited MPE development and reversed the immune microenvironment of MPE.DiscussionHere, we reveal the mechanism by which lactate induces macrophage immunosuppression via activating phenylalanine/norepinephrine signaling. …”
Get full text

Smart phone-based transcutaneous electrical acupoint stimulation as adjunctive therapy for hypertension (STAT-H trial): protocol for a cluster randomised controlled trial by Yu Wang, Xiao Wang, Ying Lin, Chao-Qun Yan, Guang-Xia Shi, Cun-Zhi Liu, Jing-Wen Yang, Jian-Feng Tu, Shi-Yan Yan, Xin-Tong Su, Li-Qiong Wang, Si-Bo Kang, Bao-Hong Mi, He-Wen Li, Xue-Zhou Wang

“…The aim of this study is to evaluate the effectiveness and safety of the smart phone-based TEAS as adjunctive therapy for hypertension.Methods and analysis This study is a 52-week cluster randomised controlled trial with 1600 hypertension patients in 32 community health service centres. Patients who meet the inclusion criteria will be randomised into usual care group or TEAS group in a 1:1 ratio. …”
Get full text

OsLAP3/OsSTRL2, encoding a rice strictosidine synthase, is required for anther cuticle formation and pollen exine patterning in rice by Dai-bo Chen, Ran Zhou, Ran Zhou, Hui-min Wang, Pei-pei Zhang, Zheng-fu Yang, Zheng-fu Yang, Dan-dan Xuan, Ying-xin Zhang, Xiao-deng Zhan, Li-yong Cao, Li-yong Cao, Shi-hua Cheng, Lian-ping Sun, Lian-ping Sun

“…Furthermore, lipid profiling demonstrated a marked reduction in both wax and cutin content. These findings establish OsLAP3 as a critical regulator of fatty acid synthesis and highlight its role in anther cuticle formation and pollen exine development. …”
Get full text

Corrigendum to “Mesenchymal Stem Cells Attenuates Hirschsprung diseases-Associated Enterocolitis by Reducing M1 Macrophages Infiltration via COX-2 Dependent Mechanism” [J Pediatr S... by Xinyao Meng, Jun Xiao, Jing Wang, Minxian Sun, Xuyong Chen, Luyao Wu, Ke Chen, Zejian Li, ChenZhao Feng, Didi Zhuansun, Jixin Yang, Xiaojuan Wu, Donghai Yu, Wei Li, Yonghua Niu, Ying He, Mingfa Wei, Feng Chen, Bo Xiong, Jiexiong Feng, Tianqi Zhu

Get full text