Joint fluid multi-omics improves diagnostic confidence during evaluation of children with presumed septic arthritis by Yolanda Peña-López, Naureen G. Tareen, Bo Zhang, Indu Raman, Carlos A. Arana, Chengsong Zhu, Yang Liu, Pratibha Selvakumar, Nicolai S. C. van Oers, Simrat Morris, Lora V. Hooper, Lawson A. B. Copley, Prithvi Raj

“…Results Ten children with suspected primary septic arthritis and two with acute hematogenous osteomyelitis (AHO) diagnoses were assessed. …”
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Analysis of employment conditions and management training needs among medical caregivers (医疗护理员从业现况及管理培训需求分析) by WANG Huaxin (王华新), LIU Guiying (刘桂英), TANG Ling (唐玲), E Haiyan (鄂海燕), GAO Bo (高波), SUN Mingli (孙明丽), ZHOU Jie (周洁), WANG Xiao (王潇)

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The cancer-associated fibroblasts interact with malignant T cells in mycosis fungoides and promote the disease progression by Yige Zhao, Yong Li, Yong Li, Panpan Wang, Mengyan Zhu, Jiaqi Wang, Bo Xie, Chenyu Tang, Yangyang Ma, Shiwen Wang, Sha Jin, Jinhui Xu, Zhao Li, Xiaoyan Zhang, Liuyu Li, Xiuzu Song, Ping Wang

“…We supposed that the tumor cells transformed from TRM-dominant phenotype to TCM-dominant phenotype during MF progressed from early-stage to advanced-stage. …”
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A bibliometric analysis of hydrogel research in various fields: the trends and evolution of hydrogel application by Zhong-Zhu Yuan, Yu-Zhou Fan, Shao-Jun Cheng, Feng-Jie Wei, Jing Gao, Chen-Xi Wang, Bo-Shuang Song, Si-Lu Tan, Si-Lian Gao, Juan-Juan Kang, Yan Liu, Sheng-Hong Li

“…This study integrated the current matrix system and characteristics of hydrogels, aiming to offer a cross-field reference for hydrogel researchers and promote the advancement of hydrogel research. Furthermore, we proposed a novel and reproducible bibliometric research paradigm, which can provide a more comprehensive analysis of the trends and trajectory of a research field. …”
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Risk of Colorectal Cancer in Ulcerative Colitis Patients: A Systematic Review and Meta-Analysis by Qing Zhou, Zhao-Feng Shen, Ben-sheng Wu, Cheng-biao Xu, Zhong-qi He, Tuo Chen, Hong-tao Shang, Chao-fan Xie, Si-yi Huang, Yu-gen Chen, Hai-bo Chen, Shu-tang Han

“…The study was registered with PROSPERO, number CRD42018102213. Findings. We included 58 studies that included 267566 UC patients. …”
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Efficacy of TIPS plus extrahepatic collateral embolisation in real-world data: a validation study by Chao Chen, Feng Zhang, Hao Wu, Wei Wu, Hui Xue, Yuzheng Zhuge, Chunqing Zhang, Guangchuan Wang, Zhengjie Li, Qiong Wu, Bo Wei, Jun Tie, Xiubin Sun, Lianhui Zhao, Yifu Xia, Jiao Xu, Peijie Li

“…This study aims to confirm the effectiveness of TIPS+E using real-world data.Methods The multicentre retrospective cohort included 2077 patients with cirrhosis who underwent TIPS±E (TIPS: 631, TIPS+E: 1446) between January 2010 and December 2022. …”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

“…S100A8/A9, also known as calprotectin or myeloid-related protein-8/14 (MRP8/14), is an alarmin primarily secreted by activated neutrophils with potent pro-inflammatory property. In this study, we explored the roles of S100A8/A9 in modulating neuroinflammation and influencing TBI outcomes, delving into the underlying mechanisms. …”
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An assessment of breast cancer HER2, ER, and PR expressions based on mammography using deep learning with convolutional neural networks by Shun Zeng, Hongyu Chen, Rui Jing, Wenzhuo Yang, Ligong He, Tianle Zou, Peng Liu, Bo Liang, Dan Shi, Wenhao Wu, Qiusheng Lin, Zhenyu Ma, Jinhui Zha, Yonghao Zhong, Xianbin Zhang, Guangrui Shao, Peng Gong

“…Mammography of patients with pathologically proven breast cancer was obtained from two centers. A deep learning-based model (CBAM ResNet-18) for predicting HER2, ER, and PR expressions was trained and validated using five-fold cross-validation on a training dataset. …”
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Preparation and quality assessment of innovative gluten-free biscuit enriched with galangal (Alpinia galanga Linn.) powder by Eatemad M. El-Sayed, Essam Mohamed Elsebaie, Shaymaa A. Hozifa, Marwa Fawzi Ahmed El-Farsy, Dalia M. El-Mesiry, Soher Abd-Elfattah ElMeslamy, Heba Ali Yousef Shaat, Rehab A. Shehata, Marwa A. Ahmed, Amira Lotfy Abd Allah, Suzan S. Ibraheim

“…All biscuits enriched with galangal powder exhibited increased DPPH and ABTS antioxidant activity compared to the control. …”
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Exploring the role of metabolic pathways in TNBC immunotherapy: insights from single-cell and spatial transcriptomics by Shi-liang Chen, Yi-Ran Fei, Yi-Ran Fei, Xin-xian Cai, Xin-xian Cai, Cong Wang, Shi-yuan Tong, Zhe-zhong Zhang, Yan-xia Huang, Dan-dan Bian, Yi-bo He, Xiao-xiao Yang

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Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Zhihan Zhao, Huan Lan, Ibrahim El-Battrawy, Xin Li, Fanis Buljubasic, Katherine Sattler, Gökhan Yücel, Siegfried Lang, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Lukas Cyganek, Jochen Utikal, Thomas Wieland, Martin Borggrefe, Xiao-Bo Zhou, Ibrahim Akin

“…In addition to the reported ion channels, INa, ICa-L, ICa-T, If, INCX, IK1, Ito, IKr, IKs IKATP, IK-pH, ISK1–3, and ISK4, we detected both the expression and currents of ACh-activated (KACh) and Na+-activated (KNa) K+, volume-regulated and calcium-activated (Cl-Ca) Cl−, and TRPV channels. …”
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Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism by Ling Xiao, Dario F. De Jesus, Cheng-Wei Ju, Jiang-Bo Wei, Jiang Hu, Ava DiStefano-Forti, Valeria Salerno Gonzales, Tadataka Tsuji, Siying Wei, Matthias Blüher, Yu-Hua Tseng, Chuan He, Rohit N. Kulkarni

“…Abstract N6-methyladenosine (m6A) is among the most abundant mRNA modifications, yet its cell-type-specific regulatory roles remain unclear. Here we show that m6A methyltransferase-like 14 (METTL14) differentially regulates transcriptome in brown versus white adipose tissue (BAT and WAT), leading to divergent metabolic outcomes. …”
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Association between neutrophil-to-eosinophil ratio and efficacy outcomes with avelumab plus axitinib or sunitinib in patients with advanced renal cell carcinoma: post hoc analyses... by Brian Rini, Mariangela Mariani, Alessandra di Pietro, Paul Nathan, Christian Kollmannsberger, Marc-Oliver Grimm, Martin H Voss, Bradley A McGregor, Mehmet A Bilen, Yoshihiko Tomita, Bo Huang, Robert Amezquita, Matthew Tucker, Yu-Wei Chen

“…Objective We report post hoc analyses of efficacy with first-line avelumab plus axitinib or sunitinib according to baseline neutrophil-to-eosinophil ratio (NER) in patients with advanced renal cell carcinoma (aRCC) from the JAVELIN Renal 101 phase 3 trial.Methods and analysis Progression-free survival (PFS), overall survival (OS) and objective response per baseline NER were analysed in the overall population and in patients with programmed death ligand 1 (PD-L1+) tumours. …”
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Hardy-Leindler-Type Inequalities via Conformable Delta Fractional Calculus by H. M. Rezk, Wedad Albalawi, H. A. Abd El-Hamid, Ahmed I. Saied, Omar Bazighifan, Mohamed S. Mohamed, M. Zakarya

“…As a result of this, some classical integral inequalities will be obtained. Also, we would have a variety of well-known dynamic inequalities as special cases from our outcomes when α=1.…”
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Extracorporeal shock wave therapy versus dexamethasone iontophoresis as a treatment for symptomatic knee osteoarthritis by Shimaa Taha Abu El Kasem, Sahar Ahmed Abdalbary, Mohamed I. Mabrouk, Engy Badreldin S. Moustafaa, Asmaa Abonour, Rania R. Mohamed

“…Purpose The goal of this pilot study was to compare and evaluate the efficacy of extracorporeal shock wave therapy (ESWT) and dexamethasone sodium phosphate (DEX-P) iontophoresis in patients who have unilateral symptomatic knee OA (KOA). …”
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The Impact of EGDT on Sepsis Mortality in a Single Tertiary Care Center in Lebanon by Christopher El Khuri, Gilbert Abou Dagher, Ali Chami, Ralph Bou Chebl, Tarek Amoun, Rana Bachir, Batoul Jaafar, Nesrine Rizk

“…Our retrospective study included 290 adult patients presenting to the ED of a tertiary center in Lebanon with severe sepsis and/or septic shock. 145 patients between years 2013 and 2014 who received protocol care were compared to 145 patients treated by standard care between 2010 and 2012. …”
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Pseudomonas aeruginosa Biofilm Removal from Two Kinds of Granite Commonly Found in Catering Kitchen by Khaddouj Amzil, Fatima Hamadi, Hassan Latrache, Rachida Mimouni, Hicham Abou Oualid, Khadija Azelmad, Aissa Saidi, Abdallah Elboulani, Mustapha Mabrouki

“…By contrast, the EP showed that the biofilm persists on two granites after NaCLO treatment, at different concentrations and contact times. …”
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