Role of Gender Equity and Disability Inclusion to Help Achieve the Larger Cause of Health for All and Attain SDG 2030 by India by Sonali Kar, Abu Bashar, Sridevi Gnanasekaran, A K Jayasree, Pillaveetil Sathyadas Indu, Kajal Srivastava

“…Gender equity now is the finer version, which is accepted and received well too, and this inclusiveness has urged us to add disability inclusion into our context of discussion. …”
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Exploring socio-demographic determinants of obesity in Jordanian women of reproductive age: insights from a nationwide survey by Mahmoud Shaaban Abdelgalil, Sara Hosny El-Farargy, Mohamed Adel Dowidar, Mohamed Abd-ElGawad

“…Result We included 4,339 Jordanian women in our study, of whom 2,189 were classified as obese and 2,150 had a normal body mass index (BMI). …”
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Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) by Junyu Yan, Kai Luo, Bo Wang, Jiaxin He, Can Li, Jiang Zhou, Wenhao Lai, Xin Zhou, Jingwei Ye, Mingzhu Pan, Yingbing Su, Weihua Gao, Kai Guo, Chengmin Zhao

“…The level of tgf-β (transforming growth factor beta), il-10 (interleukin 10), caspase3, caspase7, caspase9, occludin, zo-1 (zonula occludens-1), zo-2, claudin-12, claudin-15a, claudin-15b in the intestine of the 0.10 % group significantly increased compared with the control group (P < 0.05). …”
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D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint by Cheng-E Tu, Yong-Feng Liu, Hong-Wei Liu, Chun-Mei Jiao, Quentin Liu, Mien-Chie Hung, Peng Li, Xiang-Bo Wan, Xin-Juan Fan, Yun-Long Wang

“…The anti-cancer role of metabolite was examined using colony formation assay and APC min/+ mice. Co-immunoprecipitation, LS-MS, qRT-PCR, and immunofluorescence were performed to explore the underlying mechanisms. …”
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Chimeric antigen receptor with novel intracellular modules improves antitumor performance of T cells by Pengju Wang, Yiyi Wang, Xiaojuan Zhao, Rui Zheng, Yiting Zhang, Ruotong Meng, Hao Dong, Sixin Liang, Xinyi He, Yang Song, Haichuan Su, Bo Yan, An-Gang Yang, Lintao Jia

“…Conventional CARs employ an intracellular domain (ICD) from the ζ subunit of CD3 as a signaling module, and it is largely unknown how alternative CD3 chains potentially contribute to CAR design. Here, we obtained a series of CAR-T cells against HER2 and mesothelin using a domain comprising a single immunoreceptor tyrosine-based activation motif from different CD3 subunits as the ICD of CARs. …”
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Gallic acid protects intervertebral disc cells from ferroptosis and alleviates intervertebral disc degeneration by regulating key factors of oxidative stress by Zaishi Zhu, Zeling Huang, Chaofeng Zhang, Bo Xu, Hua Chen, Shuai Pei, Baofei Zhang, Lishi Jie, Xiaoqing Shi, Yujiang Liu, Yuwei Li, Yuwei Li, Xiaofeng Shen, Xiaofeng Shen

“…BackgroundIntervertebral disc degeneration (IDD) is a chronic degenerative disease and one of the main causes of low back pain (LBP). Currently, there is no effective treatment. …”
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Characterization and functional analysis of conserved non-coding sequences among poaceae: insights into gene regulation and phenotypic variation in maize by Yi Luo, Hang Zhai, Xiu Zhong, Bo Yang, Yang Xu, Tianhong Liu, Qi Wang, Yang Zhou, Yan Mao, Yaxi Liu, Qi Tang, Yanli Lu, Yao Wang, Jie Xu

“…Identification of CNS provides valuable information about potentially functional genomic elements, regulatory regions, and helps to gain insights into the genetic basis of crop agronomic traits. Results Here, we comprehensively analyze CNS in maize, by comparing the genomes of maize inbred line B73 (Zea mays ssp. mays), its close wild relative Zea mays spp. mexicana, and other grasses in Poaceae, including sorghum (Sorghum bicolor), foxtail millet (Setaria italica) and two adlay (Coix lacryma) cultivars. …”
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Cross-protection against homo and heterologous influenza viruses via intranasal administration of an HA chimeric multiepitope nanoparticle vaccine by Yongqiang Zhao, Jia Liu, Chun Peng, Shuangshuang Guo, Bo Wang, Longping Chen, Yating Wang, Haiwen Tang, Liming Liu, Qi Pan, Shiren Li, Jingyu Wang, Dongni Yang, Enqi Du

“…The nanoparticle vaccine co-expresses the ectodomain of haemagglutinin (H), three repeated highly conserved ectodomains of matrix protein 2 (M), and the M-cell-targeting ligand Co4B (C) in a baculovirus-insect cell system. …”
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Ganoboninketal C from Ganoderma boninense improves the efficacy of CDDP-based chemotherapy through inhibiting translesion DNA synthesis by Xiaolu Ma, Fei Yang, Ke Ma, Hongyan Shen, Junjie Han, Kai Wang, Yeran Yang, Jiawei Zhu, Ruiyuan An, Qilin Wang, Tie-Shan Tang, Bo Zhou, Hongwei Liu, Caixia Guo

“…Furthermore, we found that activating transcription factor 3 is a potential novel TLS modulator. …”
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The Economic Burden of Brucellosis Care in China: Socioeconomic Status Inequality by Hai-Bo He, Qiao-Shan Lu, Lian-Lian Wang, Muhetal Aishan, Jiang-Shan Zhao, Xian-Yan Tang, Man-Tong Zhu, Milikam Reheman, Qiu-Lan Chen, Yan-Ping Zhang

“…Therefore, our study aimed to investigate the costs and out-of-pocket expenses of brucellosis care, specifically examining the varying socioeconomic status of patients in Xinjiang, China. We collected cost and demographic data from 563 respondents and their hospital bills and employed latent variable analysis to assess socioeconomic status. …”
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Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration by Shuangpeng Jiang, Guangzhao Tian, Xu Li, Zhen Yang, Fuxin Wang, Zhuang Tian, Bo Huang, Fu Wei, Kangkang Zha, Zhiqiang Sun, Xiang Sui, Shuyun Liu, Weimin Guo, Quanyi Guo

“…Regenerative medicine involving stem cells has entered a new stage and is considered the most promising way to regenerate articular cartilage. In terms of theories on the mechanism, it was thought that stem cell-mediated articular cartilage regeneration was achieved through the directional differentiation of stem cells into chondrocytes. …”
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Inverse Agonist of Retinoid-Related Orphan Receptor-Alpha Prevents Apoptosis and Degeneration in Nucleus Pulposus Cells via Upregulation of YAP by Tongzhou Liang, Jincheng Qiu, Shaoguang Li, Zhihuai Deng, Xianjian Qiu, Wenjun Hu, Pengfei Li, Taiqiu Chen, Zhancheng Liang, Hang Zhou, Bo Gao, Dongsheng Huang, Anjing Liang, Wenjie Gao

“…Intervertebral disc degenerative disease (IDD) is the most common degenerative spine disease, which leads to chronic low back pain and symptoms in the lower extremities. In this study, we found that RORα, a member of the retinoid-related orphan receptor family, is significantly elevated in nucleus pulposus tissue in IDD patients. …”
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Expression of a Splice Variant of CYP26B1 in Betel Quid-Related Oral Cancer by Ping-Ho Chen, Ka-Wo Lee, Cheng-Chieh Hsu, Jeff Yi-Fu Chen, Yan-Hsiung Wang, Ker-Kong Chen, Hui-Min David Wang, Hurng-Wern Huang, Bin Huang

“…We investigated whether a splice variant of CYP26B1 is associated with the occurrence of ROS related oral and pharyngeal cancer. …”
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Single-cell transcriptome atlas of peripheral immune features to Omicron breakthrough infection under booster vaccination strategies by Yuwei Zhang, Shanshan Han, Qingshuai Sun, Tao Liu, Zixuan Wen, Mingxiao Yao, Shu Zhang, Qing Duan, Xiaomei Zhang, Bo Pang, Zengqiang Kou, Xiaolin Jiang, Xiaolin Jiang, Xiaolin Jiang

“…IntroductionThe high percentage of Omicron breakthrough infection in vaccinees is an emerging problem, of which we have a limited understanding of the phenomenon.MethodsWe performed single-cell transcriptome coupled with T-cell/B-cell receptor (TCR/BCR) sequencing in 15 peripheral blood mononuclear cell (PBMC) samples from Omicron infection and naïve with booster vaccination.ResultsWe found that after breakthrough infection, multiple cell clusters showed activation of the type I IFN pathway and widespread expression of Interferon-stimulated genes (ISGs); T and B lymphocytes exhibited antiviral and proinflammatory-related differentiation features with pseudo-time trajectories; and large TCR clonal expansions were concentrated in effector CD8 T cells, and clonal expansions of BCRs showed a preference for IGHV3. …”
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Paisagem Virtual e os Green Game Jam no Enfrentamento à Crise Ambiental by Rubian Diego Andrade, Elisangela Gisele do Carmo, Juliana de Paula Figueiredo, Amanda Mayara do Nascimento-Cardoso, Nara Heloisa Rodrigues, Dimitri Wo Pereira, Viviane Kawano Dias, Gisele Maria Schwartz

“… Alterações nas paisagens naturais representam preocupações mundiais. Considerando o interesse pelos videogames no contexto do lazer, torna-se instigante compreender se paisagens virtuais representam subsídios na sensibilização ambiental. …”
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Identification of Resistance to Bacterial Blight in Introgression Lines of Yuanjiang Common Wild Rice and Analysis of Its Japonica Indica Properties by Wang KAN, Hesheng YANG, Huanzhi MENG, Jiyun ZHOU, Zaiquan CHENG, Yun ZHANG, Suqin XIAO, Li LIU, Bo WANG, Fuyou YIN, Qiaofang ZHONG, Jinlu LI, Dunyu ZHANG, Ling CHEN

“…The correlation between these two traits was discussed by statistical analysis.…”
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Meta-narrative review: the impact of music therapy on sleep and future research directions by Qiaoqiao Gou, Meihui Li, Xiaoyu Wang, Xinran Yuan, Mingyi Yang, Junrui Li, Bo Wang, Dan Yang, Xiubo Ren, Miaomiao Yang, Siqi Liu, Ningning Liu, Jiaqi Han, Qiujian Xu

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3D Fusion Framework for Infarction and Angiogenesis Analysis in a Myocardial Infarct Minipig Model by Xu Zhenzhen PhD, Bo Tao PhD, MD, Yu Li MSc, Jun Zhang PhD, Xiaochao Qu PhD, Feng Cao PhD, Jimin Liang PhD

“…Then, the hearts are registered using the B-spline-based free form deformation. Finally, the [ 18 F]DG and [ 68 Ga]-NOTA-PRGD2 signals are mapped into the heart in coronary CTA, which produces a single fusion image to delineate both the cardiac structural anatomy and the functional information of myocardial viability and angiogenesis. …”
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The Role of Positron Emission Tomography Imaging in Breast Implant Illness by Siham Azahaf, MD, Karlinde A. Spit, MD, Christel J.M. de Blok, MD, PhD, Peter Bult, MD, PhD, Prabath W.B. Nanayakkara, MD, PhD, FRCP

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Intravenous Administration of Adipose-Derived Stem Cell Protein Extracts Improves Neurological Deficits in a Rat Model of Stroke by Kai Zhao, Rui Li, Changcong Gu, Long Liu, Yulong Jia, Xize Guo, Wanping Zhang, Chunying Pei, Linlu Tian, Bo Li, Jianrong Jia, Huakun Cheng, Hongwei Xu, Lixian Li

“…We demonstrated that intravenous (IV) injection of ADSC-E remarkably reduces the ischemic lesion and number of apoptotic neurons as compared to other control groups. …”
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