Determinants of Pelvic Floor Disorders among Women Visiting the Gynecology Outpatient Department in Wolkite University Specialized Center, Wolkite, Ethiopia by Ayana Benti Terefe, Tolesa Gemeda Gudeta, Girma Teferi Mengistu, Seboka Abebe Sori

“…The prevalence of pelvic floor disorder was reported to be 17.8% with 9.3% of the women experiencing urinary incontinence, 8.9% experiencing pelvic organ prolapse, and 5.9% experiencing anal incontinence. Two hundred thirty-two (85.9%) were currently married, while 110 (40.7%) were housewives. …”
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Blood Lipid Levels and Their Value as Markers of Disease Activity in Severe Ulcerative Colitis by Zhu L, Tian L, Li S, Huo L

“…This study aimed to explore the relationship between blood lipid levels and disease activity, and to evaluate the early predictive value of blood lipid levels for severe ulcerative colitis (UC).Patients and Methods: Here, we analyzed blood lipid indicators of 210 patients with UC and 210 healthy individuals who visited the hospital between August 2018 and August 2022. …”
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Predictors and prognosis of elderly hip fracture patients with perioperative atrial fibrillation: a nested case–control study by Wei Li, Aoying Min, Wei Zhao, Weining Li, Shuhan Li, Saidi Ran, Mingming Fu, Qili Yu, Junkai Kou, Zhiqian Wang, Zhiyong Hou

“…Methods An examination of hip fracture patients at the Third Hospital of Hebei Medical University, who had been hospitalized from January 2018 to October 2020 in succession, was conducted retrospectively. …”
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Effect of differences in vascular anatomy on surgical outcomes of left pancreatectomy: a retrospective study by Masahiro Fukada, Noriki Mitsui, Takeshi Horaguchi, Yuji Hatanaka, Itaru Yasufuku, Yuta Sato, Jesse Yu Tajima, Shigeru Kiyama, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi

“…Methods This was a single-center retrospective study involving 123 patients who underwent left pancreatectomy (LP). We analyzed the correlation between vascular anatomical variations, namely, (i) the root of the splenic artery (SpA; types 1 and 2), (ii) the parent artery of the dorsal pancreatic artery, (iii) confluence patterns of the left gastric vein, and (iv) the inferior mesenteric vein, and surgical outcomes. …”
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Speed of urban public transport as criterion of the justification of spatial and time-based prioritization by Yurii Yevchuk

“…For this reason, more and more attention is being paid to prioritizing urban public transport, which is capable of moving large numbers of people around the city and surrounding areas. …”
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A Nation-Wide Survey of High School Baseball Coaches’ Perceptions Indicates their Arm Care Programs Play a Role in Injury Prevention by K A Matsel, E E Weiss, R J Butler, M C Hoch, P M Westgate, T R Malone, T L Uhl

“…Among the 12.7% (n=83/654) of coaches who do not use arm care programs, the two most commonly cited reasons for not implementing arm care were lack of observed benefit (41%) and insufficient staff (31%). …”
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Inter-individual Variability in Psychological Outcomes of Supervised Exercise in Adults with Type 2 Diabetes / Variabilidad interindividual en los efectos psicológicos del ejercici... by Marco Guicciardi, Romina Lecis, Davide Massidda, Lucina Corgiolu, Adelina Porru, Matteo Pusceddu, Francesca Spanu

“… Abstract: Exercise is a key component in the management of Type 2 Diabetes Mellitus (T2DM), however despite the strong evidence of its protective effects, a majority of the population with this diagnosis remains inactive and those who start an exercise program are not willing to train themselves over the long-term. …”
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Fractionated robotic radiosurgery for unfavorable nonfunctioning pituitary macroadenoma: 5-year outcomes from a single institution protocol by Akrita Bhatnagar, Monica Pernia Marin, Jonathan W. Lischalk, Min Ji Koh, Siviero Agazzi, Simeng Suy, Brent T. Harris, Susmeeta T. Sharma, Edward Aulisi, Amjad Anaizi, Mohamed H. Khattab, Walter C. Jean, Walter C. Jean, Sean P. Collins, Brian T. Collins

“…Long-term outcomes are established in the literature for single-fraction frame-based radiosurgery, but mature outcomes are lacking for fractionated frameless radiosurgery. We report our institution’s 5-year efficacy and toxicity results for unfavorable nonfunctioning pituitary macroadenoma patients treated with 5-fraction robotic radiosurgery.MethodsBetween 2010 and 2020, patients who completed 5-fraction robotic radiosurgery for the treatment of unfavorable nonfunctioning pituitary macroadenomas were included. …”
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Reduction of pain and functional disability over time in patients treated with zavegepant: a post-hoc analysis of the BHV3500-301 phase 3 randomized controlled trial by Lauren Powell, Fiona O’Sullivan, Pramoda Jayasinghe, Basia Rogula, Feng Dai, Jessica Cirillo, Samantha Sweeney, Lucy Abraham, Jessica Ailani

“…Conclusion This post-hoc analysis demonstrates the benefit of zavegepant nasal spray over placebo on two patient-centric endpoints: time spent with pain freedom and normal functioning over 48-h post-dose. …”
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Real-World Life Analysis of a Continuous Glucose Monitoring and Smart Insulin Pen System in Type 1 Diabetes: A Cohort Study by Paola Pantanetti, Giovanni Cangelosi, Sara Morales Palomares, Gaetano Ferrara, Federico Biondini, Stefano Mancin, Gabriele Caggianelli, Mauro Parozzi, Marco Sguanci, Fabio Petrelli

“…Methods: A retrospective observational study was conducted among adults with T1D who initiated Medtronic Smart MDI therapy. Participants were enrolled voluntarily at the Diabetes and Nutrition Clinic in Ast Fermo, Marche Region, Italy. …”
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Medullary thyroid cancer in MEN2 pediatric/adolescent carriers of RET mutation: genotype/phenotype correlation and outcome in a retrospective series of 23 patients by Guenda Di Benedetto, Ignazio Barca, Laura De Gregorio, Claudia Scollo, Fiorenza Gianì, Federica Martorana, Marco Russo, Francesco Frasca, Gabriella Pellegriti, Gabriella Pellegriti, Giulia Sapuppo

“…BackgroundMultiple endocrine neoplasia type 2 syndrome (MEN2) is a hereditary disease resulting from mutations of the rearranged during transfection (RET) protooncogene subclassified into MEN2A [medullary thyroid carcinoma (MTC), pheochromocytoma, and primary hyperparathyroidism] and MEN2B (MTC, pheochromocytoma, Marfanoid habitus, mucous neuromas, and intestinal ganglioneuromatosis). …”
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Social-ecological perspective on the suicidal behaviour factors of early adolescents in China: a network analysis by Xueying Zhang, Yuan Li, Juan Chen, Peiying Li, Mengyuan Yuan, Yonghan Li, Gengfu Wang, Puyu Su

“…Identifying modifiable risk factors during this critical phase is a priority to inform effective suicide prevention strategies.Aims To explore the risk and protective factors of suicidal behaviours (ie, suicidal ideation, plans and attempts) in early adolescence in China using a social-ecological perspective.Methods Using data from the cross-sectional project ‘Healthy and Risky Behaviours Among Middle School Students in Anhui Province, China’, stratified random cluster sampling was used to select 5724 middle school students who had completed self-report questionnaires in November 2020. …”
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Clinical Efficacy Between Intravenous Paracetamol and Intravenous Fentanyl for Propofol Deep Sedation in Colonoscopy: A Randomized Controlled Trial by Thiparporn T, Supan W, Amornyotin S

“…Due to a lack of data on intravenous paracetamol, we aimed to investigate the clinical efficacy of intravenous paracetamol compared to intravenous fentanyl under propofol deep sedation for colonoscopy.Methods: A total of 225 patients who underwent colonoscopy at Siriraj Hospital were randomly assigned to two groups. …”
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Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract by Chun-Nun Chao, Chi-Feng Hung, Wei‑Hong Lai, Chun-Liang Tung, Wan-Yun Yeh, Kai-Wu Yang, Meilin Wang, Ya-Yan Lai, Pei-Lain Chen, Cheng-Huang Shen

“…In the UTUC advanced stages, the OR of virus and LT expression was 3.18-fold higher compared to those who do not require chemotherapy. Conclusions JCPyV infection is highly prevalent in UTUC, and the presence of CKD concurrent with high expressions of LT and mutant p53 proteins in patients may be a useful indicator for chemotherapy and poor prognosis.…”
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Unveiling the pathways: identifying the multifaceted determinants of low birth weight among neonates in low-income countries: a case-control study by Dube Jara, Angefa Ayele, Dukele Boneya, Jitu Beka, Miesa Gelchu, Alo Edin

“…Background Low birth weight, as defined by the WHO, refers to the weight of a neonate below 2500 g at birth and is a significant public health concern globally, with both short- and long-term consequences. …”
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Baseline Smartphone App Survey Return in the Electronic Framingham Heart Study Offspring and Omni 1 Study: eCohort Study by Jian Rong, Chathurangi H Pathiravasan, Yuankai Zhang, Jamie M Faro, Xuzhi Wang, Eric Schramm, Belinda Borrelli, Emelia J Benjamin, Chunyu Liu, Joanne M Murabito

“…We also aim to report survey results for selected baseline surveys and participant experience with this study’s app. …”
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Epilepsy care pathway: The Finnish model by Reetta Kälviäinen, Zakarya Hadj‐Allal, Jarkko Kirjavainen, Reina Roivainen, Tarja Linnankivi, Jukka Peltola, Kai Eriksson, Salla Lamusuo, Tuire Lähdesmäki, Johanna Annunen, Päivi Vieira, Virpi Tarkiainen, Leena Jutila, Anni Saarela, Leena Kämppi, Liisa Metsähonkala, Eija Gaily, Niina Lähde, Jaana Antinmaa, Sini Erme, Anna‐Leena Pirttisalo, Jari Virolainen, Milla Ylijoki, Laura Kela, Jonna Komulainen‐Ebrahim, Paula Sorjonen, Finnish Severe Epilepsy Coordination Group

“…They must align with the WHO Global Action Plan on Epilepsy, ensuring best practices and cost‐effective management. …”
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Risk factors associated with the failure of local methotrexate combined with minimally invasive surgery for late cesarean scar pregnancy by Xiao-Tong Cheng, Yan-Song Liu, Dan-Yang Song, Xiao-Cui Nie, Yu-Shi Xiang, Ju-Min Niu

“…Methods This retrospective case-control study was conducted between January 2016 and December 2023, involving patients with late CSP (≥ 8 weeks) who received local MTX injection combined with either hysteroscopic or laparoscopic surgery. …”
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The variation in the number of roots and canals morphology of permanent mandibular first molar teeth by using cone beam computed tomography imaging in a sample of Erbil city by Hassan Ali Mahmoyd Albarzanji, Alaa Muhamed Sadiq Muhamed Jamil

“…The data analysis for the number of canals in study sample indicated that the mesial root had two canals in all sample while in distal root showed that 41 mandibular first molars showed two canals which were about 29.1% and 100 mandibular first molars showed one canal which was about 70.9%. …”
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Pan-tumor analysis to investigate the obesity paradox in immune checkpoint blockade by Evan J Lipson, Ludmila Danilova, Elizabeth M Jaffee, Won Jin Ho, Mark Yarchoan, Yasser Ged, Jean Hoffman-Censits, Jennifer Durham, Sanjay Bansal, Chester Kao, Rajat Mohindra, Stephanie L Alden, Tanguy Y Seiwert, Soren Charmsaz, Howard L Li, Kabeer Munjal, Hua-Ling Tsai, Alexei Hernandez, Erin M Coyne, Rachel Garonce-Hediger, Laura Tang, Marina Baretti, Kathryn Howe, G Scott Chandler, Madelena Brancati, Aanika Warner, Ervin Griffin, Mari Nakazawa, Chris Thoburn, Jennifer Gizzi, Nicole E Gross, Elsa Hallab, Sarah S Shin, Aditi Guha

“…To interrogate mechanisms of divergent immune responses in obese and non-obese patients, we examined the relationship among obesity status, clinical responses, and immune profiles from a diverse, pan-tumor cohort of patients treated with ICI-based therapy.Methods From June 2021 to March 2023, we prospectively collected serial peripheral blood samples from patients with advanced or metastatic solid tumors who received ICI as standard of care at Johns Hopkins. …”
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