Characterising SRD5A2 Gene Variants in 37 Indonesian Patients with 5-Alpha-Reductase Type 2 Deficiency by Nanis S. Marzuki, Firman P. Idris, Hannie D. Kartapradja, Alida R. Harahap, Jose R. L. Batubara

“…In addition, the respective sensitivities for detecting severe 5ARD2 cases using T/DHT (cutoff: 10) and urinary Et/An ratios (cutoff: 0.95) were 85% and 90%, whereas mild cases were only identified with 64.7% and 47.1% sensitivity, respectively. Although we were unable to identify clear correlations between genotypic and phenotypic characteristics in this study, we clearly showed that individuals who were homozygous or compound heterozygous for any of the harmful mutations were more likely to exhibit classic 5ARD2 phenotypes, lower EMS, female assignment at birth, and virilisation during puberty. …”
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The effect of Baby-Friendly Hospital Initiative compliance on the association between mode of birth and breastfeeding initiation in Sri Lanka by Laavanya Lokeesan, Elizabeth Martin, Rebecca Byrne, Yvette D. Miller

“…Globally, there is some evidence that exposure to mother-baby skin-to-skin contact (BFHI Step 4) is lower in caesarean section births. Therefore, we aimed to determine how breastfeeding initiation varies by mode of birth in Sri Lanka, and the extent to which women’s exposure to BFHI practices explains any associations found. …”
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Creating pragmatic, rapid‐cycle, evidence‐based innovation: The Kaiser Permanente Northern California Delivery Science and Applied Research (DARE) program by Douglas A. Corley, Julie A. Schmittdiel, Smita Rouillard, Yi‐Fen Chen, Tracy A. Lieu

“…Conclusions High‐volume, evidence‐based innovation programs can be important, scale‐able, reproducible models for different settings for increasing quality, affordability, sustainability, value, and equity in healthcare and furthering the difficult‐to‐achieve concept of developing sustainable learning healthcare systems.…”
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Continued Implementation and Use of a Digital Informal Care Support Platform Before and After COVID-19: Multimethod Study by Nikita Sharma, Christian Wrede, Sofia Bastoni, Annemarie Braakman-Jansen, Lisette van Gemert-Pijnen

“…Those included, for example, alternative ways to engage with end users, incorporating automated user support and large-scale communication features, considering the fluctuation of user groups, and addressing data transparency concerns in health care. …”
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Anlotinib in combination with metronomic chemotherapy in HER2-negative metastatic breast cancer: an observational and retrospective study by Jiaxuan Liu, Jiayang Zhang, Huiping Li, Guohong Song, Lijun Di, Hanfang Jiang, Ying Yan, Huan Wang, Jing Wang, Xiaoran Liu, Bin Shao, Qiao Li

“…We conducted the present retrospective study to evaluate the efficacy and safety of anlotinib plus MCT for HER2 negative MBC. …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

“…One of the main treatment goals is improving quality of life (QoL), particularly for patients with lower-risk MDS (LR-MDS) who may live longer with compromised QoL. …”
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Laboratory diagnosis of H. pylori among dyspeptic patients using Culture and Rapid urease test by Hogir Mohammed Shukri Saadi, Ali Yahya Saeed

“…Medical laboratory analysis of H. pylori infection is done by two ways invasive and non- invasive methods. Invasive techniques frequently disapproved by patients because it is inconvenient but still remain reliable methods. …”
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Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes by Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

“…Methods We performed a retrospective analysis of prospectively collected data from consecutive adult AIS‐LVO patients with successful reperfusion (modified Thrombolysis in Cerebral Infarction 2b/2c/3). …”
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Family planning and preimplantation testing: family experiences in congenital adrenal hyperplasia by Jessica L. Sandy, Jessica L. Sandy, Jessica L. Sandy, Grant Betts, Jessica L. Harper, Suzanne M. Nevin, Suzanne M. Nevin, Suzanne M. Nevin, Rebecca Deans, Rebecca Deans, Rebecca Deans, Kristen A. Neville, Kristen A. Neville

“…Eight decided to have additional children of whom seven agreed to participate. Thematic analysis identified six key domains. …”
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Procedural sedative effect of remimazolam in ICU patients on invasive mechanical ventilation: a randomised, prospective study by Youli Tian, Jintong Li, Minggen Jin, YiHua Piao, Jisheng Sheng, Zhixiong Mei, Qingsong Cui, Lilin Li

“…Under the same analgesic regimen, the two groups received remimazolam and propofol for procedural sedation. …”
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Analisis Kesalahan dalam Pembuktian Teorema Bilangan Bulat pada Mahasiswa IKIP Budi Utomo Malang by Nok Izatul Yazidah, Yunis Sulistyorini, Era Dewi Kartika

“…The subject of this research is the mathematics education student of IKIP Budi Utomo who is teaching number theory course. This research is a qualitative descriptive study. …”
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Application of deep learning model based on unenhanced chest CT for opportunistic screening of osteoporosis: a multicenter retrospective cohort study by Chengbin Huang, Dengying Wu, Bingzhang Wang, Chenxuan Hong, Jiasen Hu, Zijian Yan, Jianpeng Chen, Yaping Jin, Yingze Zhang

“…Key Points The application of unenhanced chest CT is increasing. Most people do not consciously use DXA to screen themselves for osteoporosis. …”
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Anti-Adhesive Podocalyxin Expression Is Disrupted in Recurrent Implantation Failure by Mustafa Tas

“…This study was designed to determine whether switching between the anti-adhesive podocalyxin (PDX) and adhesive HOXA10 receptivity modulator occurs in the endometrium of women with recurrent implantation failure (RIF). <b>Methods:</b> Twenty-four patients with RIF who could not conceive for three or more cycles despite good-quality embryo transfer constituted the study group. …”
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The Clinicopathological Characteristics and Prognoses of dMMR Gastric Adenocarcinoma Patients by Jie Wang, Yanfeng Xi, Jian Zhao, Xuetong Rong, Weidong Lu, Yusheng Wang

“…From May 2011 to November 2020, GC patients who underwent surgery with dMMR confirmed by immunohistochemistry (IHC) at the Affiliated Cancer Hospital of Shanxi Medical University were selected. …”
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Usage and cost-effectiveness of anti-psychotics in psychiatry OPD among various clinical conditions: A prospective observational study in a tertiary care center by Reshabh Saini, Chandrasekaran Dhinakaran, Rohit Raina, Ramanathan Gandhibabu, Kathiresan Krishnasamy

“…Conclusion: In this study, we had observed the usage and types of anti-psychotic drugs to control and minimize the different psychotic symptoms among the OPD patients. …”
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Clinical report of Mediterranean fever in a child in Ukraine – Don’t miss it! by К.Y. Pashenko, Т.V. Frolova, Y.V. Кarpushenko, G.R. Muratov, О.М. Savvo, Т.О. Khalturina, О.М. Ashcheulov

“…This article presents a clinical case of FMF in a 4-year-old child who was admitted to our hospital with complaints of fever, abdominal pain, vomiting, and stool retention. …”
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Contemporary Results of Transcatheter Aortic Valve Replacement in Obese Patients by T. Owais, M. El Garhy, P. Lauten, M. Haensig, H. Lapp, P. C. Schulze, T. Kuntze

“…We stratified the patients according to BMI. Results. …”
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A Clinical Monitoring Program of COVID-19 Outpatients: A Prospective Cohort Study by Hossein Kasiri, Cyrus Mahjub, Mohammadreza Mazaeri, Fahimeh Naderi-Behdani, Aliyeh Bazi, Monireh Ghazaeian, Sahar Fallah

“…Results. From 323 patients who had been referred to the emergency department, 105 individuals were recruited between April 26 and August 2, 2020. …”
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Pharmacists’ perceptions of the new pharmaceutical vaccination service in Romania: a comprehensive first two-years evaluation by Corneliu-Florin Buicu, Mihaela-Simona Naidin, Marius Calin Chereches, Marina-Daniela Dimulescu, Adina Turcu-Stiolica

“…In terms of overall satisfaction, 23% of pharmacists reported being very satisfied, while 39% indicated they were satisfied with the new pharmaceutical service they were providing. …”
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Quantification of ecosystem services from mangrove silvofishery by E. Sumarga, D. Rosleine, G.B. Hutajulu, R.P. Plaurint, Tsabita ., M. Basyuni, S.H. Larekeng, M.F. Taqiyudin, N.N. Shohihah, H. Ali

“…To quantify fisheries production, interviews were conducted with area managers and pond farmers who are engaged in silvofishery practices within the region. …”
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