Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient by Amina M. Bagher

“…Individuals carrying the CYP2C9∗3 or CYP2C8∗3 non-functional alleles have reduced enzyme activities resulting in elevated ibuprofen plasma concentrations and half-life. We presented a case of a 31-year-old Saudi female patient with a history of rheumatoid arthritis (RA) who had taken ibuprofen at 600 mg twice daily for eight weeks. …”
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Comparison between Rocuronium and Atracurium Effect on Blood Pressure during General Anaesthesia in Baghdad Hospital by Adel Amen Hama, Noor Faris Hoobi, Sara Emad Majeed

“…The study recruited 50 adult patients, divided in to two groups the rocuronium drug groups which included 25 patients and atracurium drug group which included 25 patients, age ranged from (18-60 years) of both sexes who were (ASAI and ASAII) patients undergoing (elective surgeries) in Baghdad education hospital during the period from (October 2019 to March 2020). …”
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Association between exposure to ambient air pollutants and metabolic syndrome in the vicinity of the Taklamakan Desert by Zhe Wang, Weidong Ji, Yushan Wang, Lin Li, Kai Wang, Hongze Liu, Yining Yang, Yi Zhou

“…A 10 μg/m³ increase in concentration was associated with the following respective odds ratios: PM1 (1.341, 95 % CI: 1.331, 1.351), PM2.5 (1.036, 95 % CI: 1.034, 1.037), PM10 (1.006, 95 % CI: 1.005, 1.007), O3 (1.385, 95 % CI: 1.374, 1.396), and CO (1.015,95 %, CI: 1.0147, 1.016). …”
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The Obesity Paradox Revisited: Is Obesity Still a Protective Factor for Patients With High Comorbidity Burden or High-Complexity Procedures? by Hyo Jin Son, BSc, Denise W. Gee, MD, David Gomez, MD, PhD, James J. Jung, MD, PhD

“…Then, we investigated the subgroups stratified by procedural complexity and comorbidity burden using a modified Charlson Comorbidity Index (mCCI) and mortality probability. …”
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Nucleotide variation in Foxp3 gene and prognosis of bladder cancer: a case-control study by Qin Li, Yan Zhang, Yan Zhang, Min Su, Yaping Song, Yanyun Wang, Bin Zhou, Lin Zhang

“…SPSS and online SNPstats software were used to determine the disparities between groups.ResultsFor the rs3761548 C/A polymorphism, patients with the CA/AA genotype showed a notable decrease in the case group (22.1% versus 34.8%, P = 0.003, OR = 0.61, 95%CI = 0.44-0.85), and the heterozygous CA genotype presented a distinctly lower risk for BC (P = 0.0003, OR = 0.43, 95%CI = 0.26-0.70). Notably, individuals who were homozygous for the AA genotype demonstrated a markedly lower overall survival (OS) rate compared to those with the CC/CA genotypes (P = 0.03, OR = 5.89, 95%CI = 1.23-28.15), after adjusting for factors such as age, gender, smoking status, tumor grade, metastasis, and clinical stage. …”
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Application of Chain Nursing Process in the Nursing of Elderly Inpatients with Implantable Venous Infusion Port by Juan Hu, Li Zhou, Juanying Ding

“…After intervention, the scores of GAD-7 and AIS in the two groups were reduced compared with those before intervention, and the above scores in the study group were lower than those in the routine group (P<0.05). …”
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Accessibility of Patients With Special Healthcare Needs to Dental Care in the Eastern Province of Saudi Arabia: A Multicentre Study From Perspective of Caregiver and Dental Care Pr... by Tarek Ezzeldin, Mazin Algahtani, Nadia Abdulrahman Alghannam, Faisal Abdulkareem Alsafran, Intisar Ahmad Siddiqui, Hebah Zaki Al-Ghanim, Basma Mohamed Bader, Abdullah Abdulatif Alshubat, Adnan Hamad Almarry, Hussein Hejji IbnAhmed, Sarah Abdulhadi Kanakri, Reem Babiker Eltayeb, Mohammed Ibrahim Almuaybid, Khalaf Ali Al-Wasi

“…In addition, the perspective of dental care providers who care for patients with SCN and the factors affecting the provision of treatment was also appraised. …”
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Screening for monoclonal B-lymphocyte expansion in a hospital-based Chinese population with lymphocytosis: an observational cohort study by Yue Wang, Jing Li, Peng Liu, Jiadai Xu, Zheng Wei

“…This study was designed to find the most cost-effective way to screen for asymptomatic B-LPD.Design Observational study.Setting A lymphocytosis screening project was conducted at a large-scale hospital among the Chinese population.Participants For 10 consecutive working days in 2018, 22 809 adult patients who received a complete blood count (CBC) were reviewed. …”
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Predicting the risk of gastroparesis in critically ill patients after CME using an interpretable machine learning algorithm – a 10-year multicenter retrospective study by Yuan Liu, Songyun Zhao, Wenyi Du, Wei Shen, Ning Zhou

“…The clinical data of critically ill patients transferred to the intensive care unit (ICU) post-CME were meticulously analyzed to identify key risk factors associated with the development of gastroparesis.MethodsWe gathered 34 feature variables from a cohort of 1,097 colon cancer patients, including 87 individuals who developed gastroparesis post-surgery, across multiple hospitals, and applied a range of machine learning algorithms to construct the predictive model. …”
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Association between occupational exposure to gasoline and anemia: a retrospective cohort study in China by Lan Lin, Hongmei Cao, Beining Wu, Jin Wang, Lin Song, Weiling Chan, Geyang Li, Li Zhou, Jing Xiao, Lejia Zhu, Yulong Lian

“…Anemia was diagnosed according to WHO guidelines on hemoglobin cutoffs to define anemia in individuals and populations. …”
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The clinical application and anatomical analysis of proximal peroneal artery perforator in free fibula flap based on CTA by Yitong Zhao, Danwei Xiang, Lina Song, Zhujiajun Cui, Xingwu Zheng, Tianyu Zhang, Huihui Yang, Yongzhen Fu, Qilin Liu

“…Methods A comprehensive review was conducted involving 50 patients who underwent CTA examinations. Three-dimensional reconstruction of DICOM data was utilized to document the presence, quantity, location, and variations of proximal perforators. …”
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Results of biochemical and histological studies after restoration of bone defects using cellular technologies in dental patients by А.V. Bambuliak, N.B. Kuzniak, L.Y. Lopushniak, І.І. Dronyk, О.О. Myhal

“…The clinical material included examination of 79 patients who underwent replacement of bone defects of the alveolar processes and/or an alveolar part of the appropriate jaw by means of different osteoplastic materials and their combinations or without their application (the control group). …”
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Case report: Trauma-induced Klebsiella pneumoniae invasive syndrome presenting with liver abscess, lung abscess, endophthalmitis, and purulent meningitis by Hong-qiao Chen, Zhen-hua Mo, Wu-xiao Wei

“…Trauma may facilitate invasive infections by disrupting immune barriers and compromising local tissue integrity, creating entry points for pathogens.Case presentationThis study reports a case of a 72-year-old male who developed multiple infections, including liver abscess, lung abscess, left endophthalmitis, and purulent meningitis, following a traumatic fall. …”
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Sociodemographic disparities in influenza vaccination among older adults in United States by Huan Tao, Jin Chen, Xue Zhang, Xue Zhang, Tao Wang, Nenggang Jiang, Yongqian Jia

“…Compared to non-Hispanic Black people with an income below $25,000 and education less than high school, the ORs were significantly higher among non-Hispanic whites [2.12, (95% CI 1.97–2.28)], non-Hispanic Black people [1.30, (95% CI 1.18–1.44)], and Hispanics [1.40, (95% CI 1.24–1.59)] earning above $50,000 and education above high school. Those who received an influenza vaccination tended to be concentrated in the high-income group and high-education group.ConclusionThere are substantial racial and socioeconomic disparities in influenza vaccination uptake among individuals aged 65 years or older. …”
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Association between maternal infertility treatment and child neurodevelopment: findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study in Miyagi a... by Mami Ishikuro, Shinichi Kuriyama, Shigeo Kure, Junichi Sugawara, Taku Obara, Nobuo Yaegashi, Tatsui Otsuka, Aoi Noda, Keiko Murakami, Fumihiko Ueno, Fumiko Matsuzaki, Tomomi Onuma, Zen Watanabe, Naomi Shiga, Noriyuki Iwama, Hamada Hirotaka, Masahito Tachibana, Hiroaki Tomita, Masatoshi Saito

“…Objectives This study aimed to examine the association between infertility treatment and neurodevelopment in children at 2 and 3.5 years of age.Design Prospective cohort study.Setting and participants The study population consisted of mother–child pairs who participated in the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study in Miyagi and Iwate Prefectures, Japan. …”
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Correlations between Placental Thickness and Neonatal Outcomes: A Detailed Analysis at 32 and 36 Weeks by Alka Agrawal, Prachi Shukla, Vivek Yonati, Sapna Ahlawat, Rinku Meena, Deepak Ahlawat, Neelesh Patel

“…It is important to measure PT along with biometric parameters during ultrasound examinations for pregnant women. In addition, we observed the interaction of different factors, including body mass index and parity.…”
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The Efficacy and Safety of the Chinese Herbal Formula, JTTZ, for the Treatment of Type 2 Diabetes with Obesity and Hyperlipidemia: A Multicenter Randomized, Positive-Controlled, Op... by Xiaotong Yu, Lipeng Xu, Qiang Zhou, Shengping Wu, Jiaxing Tian, Chunli Piao, Hailong Guo, Jun Zhang, Liping Li, Shentao Wu, Meizhen Guo, Yuzhi Hong, Weirong Pu, Xiyan Zhao, Yang Liu, Bing Pang, Zhiping Peng, Song Wang, Fengmei Lian, Xiaolin Tong

“…A total of 450 participants with T2D (HbA1c ≥ 7.0%; waist circumference ≥ 90 cm and 80 cm in males and females, resp.; and triglycerides (TG) ≥ 1.7 mmol/L) were randomly assigned, in equal proportions, to two groups in this multicenter randomized, positive-controlled, open-label trial. …”
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Prediction of subsequent vertebral fracture after percutaneous vertebral augmentation using MRI-based vertebral bone quality and CT-based Hounsfield units: a retrospective cross-se... by Youdi Xue, Kun Shi, Weixiang Dai, Chao Ma, Jie Li

“…Computed tomography (CT)-based Hounsfeld units (HU) and magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score can evaluate osteoporosis quantitatively, hyperlipidemia(HLP) might affect measurement result of VBQ score. …”
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Data-Driven Decision Support Tool Co-Development with a Primary Health Care Practice Based Learning Network [version 2; peer review: 2 approved] by Daniel Lizotte, Eric Sutherland, Paulino Lucamba, Sandra Fitzpatrick, Kelly Angevaare, Sara Bhatti, Jennifer Rayner, Jacqueline Kueper

“…Background The Alliance for Healthier Communities is a learning health system that supports Community Health Centres (CHCs) across Ontario, Canada to provide team-based primary health care to people who otherwise experience barriers to care. This case study describes the ongoing process and lessons learned from the first Alliance for Healthier Communities’ Practice Based Learning Network (PBLN) data-driven decision support tool co-development project. …”
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Atypical Mucin Expression Predicts Worse Overall Survival in Resectable Pancreatic Ductal Adenocarcinoma by Yunzhen Qian, Yitao Gong, Yu Liu, Yusheng Chen, Ruijie Wang, Zhengjie Dai, Xuan Zou, Yesiboli Tasiheng, Guopei Luo, Xuan Lin, Xu Wang, He Cheng, Xianjun Yu, Chen Liu

“…However, the relationship between mucin expression and prognosis of PDAC patients has been controversial in the past decades; therefore, we aim to figure out the association of mucin expression with survival in PDAC patients who underwent radical resection. …”
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