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- 44.83 rheumatology, orthopedics 2
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Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease
Published 2025-01-01“…A total of six key genes related to amino acid metabolism were identified, including ALDH18A1, CENPF, CSAD, CTH, CYP27B1, HBB. Results: All six genes exhibited promising diagnostic capabilities (AUC:0.7 to 0.9). …”
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4463
Simultaneous Quantification of Brigatinib and Brigatinib-Analog in Rat Plasma and Brain Homogenate by LC-MS/MS: Application to Comparative Pharmacokinetic and Brain Distribution St...
Published 2019-01-01“…The simple and sensitive LC-MS/MS method was successfully applied to the pharmacokinetic and brain distribution studies following a single oral administration of brigatinib and brigatinib-analog to rats. The above studies would lay a good foundation for the further applications of brigatinib and brigatinib-analog.…”
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Sources analysis and risk assessment of heavy metals in soil in a polymetallic mining area in southeastern Hubei based on Monte Carlo simulation
Published 2025-01-01“…The main findings are as follows: (1) Among the heavy metals present in the soil, copper (Cu) has the highest average concentration at 278.54 mg/kg, followed by zinc (Zn) at 161.16 mg/kg, chromium (Cr) at 75.23 mg/kg, nickel (Ni) at 30.38 mg/kg, arsenic (As) at 22.53 mg/kg, cadmium (Cd) at 0.76 mg/kg, and mercury (Hg) at 0.14 mg/kg; (2) The distribution of heavy metal concentrations exhibits significant regional variations, with the spatial pattern of pollution indicating that TLS is more affected than JLS, as evidenced by the Pollution Load Index (PLI) values; (3) Three potential sources of heavy metals were identified: natural sources, anthropogenic activities (including industrial production and agricultural practices), and atmospheric deposition (both dry and wet); (4) While severe contamination levels of specific metals such as copper and cadmium are observed in JLS and TLS soils, the overall contamination is mild, suggesting complex contamination dynamics; (5) Cadmium poses a moderate to high ecological risk, being the most sensitive factor in the comprehensive ecological risk assessment with a contribution rate of 65.2 %; (6) The concentrations of heavy metals in the soil present certain health risks, with children being more vulnerable than adults. …”
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Production Data Analysis and Practical Applications in the Sulige Tight Gas Reservoir, Ordos Basin, China
Published 2021-01-01“…Successful exploitation of tight sandstone gas is one of the important means to ensure the “increasing reserves and production” of the oil and gas initiative and also one of the important ways to ensure national energy security. To further improve the accuracy of historical matching of field data such as gas production and bottom-hole pressure during the production process of this type of gas reservoir, in this study, a new expression of wellbore pressure for the uniform flow of vertical fractured wells in Laplace space based on the point sink function model of vertical fractures in tight sandstone gas reservoirs is constructed. …”
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Advances in the application of multi-omics and machine learning technologies in sepsis research
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Alloy-based verification of Web service composition
Published 2012-11-01Subjects: “…Web service…”
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Effect of Low-Frequency Vibration on Muscle Response under Different Neurointact Conditions
Published 2019-01-01“…Variables including dynamic muscle force, vibration acceleration, and displacement were recorded in two conditions, with and without the stretch reflex. …”
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Review of Digital Construction of UHV Projects Based on Building Information Modeling Technology
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Association of β-Blocker Therapy at Discharge with Clinical Outcomes after Acute Coronary Syndrome in Patients without Heart Failure
Published 2020-01-01“…Among these, we analyzed 5,631 ACS patients who were discharged with LVEF≥40%. …”
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Simulating method for TCP aggregated traffic of large scale network
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Digital Twin-Empowered Robotic Arm Control: An Integrated PPO and Fuzzy PID Approach
Published 2025-01-01“…However, the control and error management of robotic arms in digital twin systems pose challenges. In this paper, we present a digital twin-empowered robotic arm system and propose a control policy using deep reinforcement learning, specifically the proximal policy optimization approach. …”
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Activated Human Umbilical Cord Blood Platelet-Rich Plasma Enhances the Beneficial Effects of Human Umbilical Cord Mesenchymal Stem Cells in Chemotherapy-Induced POF Rats
Published 2021-01-01“…The combined transplantation of HucMSCs and ucPRP resulted in more stem cells being retained in the ovaries of POF rats, the estrus cycle of the POF rats being restored, the levels of serum E2, AMH, and FSH improving, and damaged follicles beginning to grow. …”
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Matrix vesicle-inspired delivery system based on nanofibrous chitosan microspheres for enhanced bone regeneration
Published 2025-02-01“…Materials Today Bio…”
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Path-Following Control of Wheeled Planetary Exploration Robots Moving on Deformable Rough Terrain
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Hepatoma cell-derived exosomal SNORD52 mediates M2 macrophage polarization by activating the JAK2/STAT6 pathway
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Female Gender Remains a Significant Barrier to Access Cataract Surgery in South Asia: A Systematic Review and Meta-Analysis
Published 2020-01-01“…To determine whether the female gender is a barrier for the access to cataract surgery services in South Asia in the last two decades. Methods. Eligible cross-sectional studies were identified via computer searches and reviewing the reference lists of the obtained articles. …”
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Influence of Process on the Formation of Main Taste Substances and Quality of Chuanhong Congou Black Tea
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Research on co-spectrum sharing technology in LTE 2.1 GHz
Published 2022-12-01Subjects: Get full text
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