Neoadjuvant pyrotinib and trastuzumab in HER2-positive breast cancer with no early response (NeoPaTHer): efficacy, safety and biomarker analysis of a prospective, multicentre, response-adapted study by Fei Wang, Yongjiu Wang, Bin Xiong, Zhenlin Yang, Jingfen Wang, Yumin Yao, Lixiang Yu, Qinye Fu, Liang Li, Qiang Zhang, Chao Zheng, Shuya Huang, Liyuan Liu, Chun Liu, Huaibo Sun, Beibei Mao, Dong-Xu Liu, Zhigang Yu

“…These findings suggest that adding pyrotinib may benefit patients who do not respond to neoadjuvant trastuzumab plus chemotherapy. …”
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The effectiveness of posterior Schanz screw system in the anatomical restoration of thoracolumbar vertebral burst fractures: A 10-year single-institution experience by Pietro Domenico Giorgi, Simona Legrenzi, Ye Youchen, Bove Federico, Giuseppe Rosario Schirò

“…Load-sharing score >8, body mass index >26, preoperative radiological parameters (SI, SK, and anterior body height [ABH] ratio), and postoperative ABH ratio were identified as significant predictors of correction loss >10°. …”
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Does Isoniazid Preventive Therapy Provide Better Treatment Outcomes in HIV-Infected Individuals in Northern Ethiopia? A Retrospective Cohort Study by Tesfay Mehari Atey, Helen Bitew, Solomon Weldegebreal Asgedom, Asrat Endrias, Derbew Fikadu Berhe

“…Early antiretroviral therapy (ART), isoniazid preventive therapy (IPT), and isoniazid-rifapentine (3HP) are effective strategies for preventing tuberculosis (TB) among people living with HIV (PLHIV). The study aimed to determine the effect of IPT on the TB incidence, follow-up CD4+ T cells, and all-cause mortality rate. …”
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Diagnostic Accuracy of Next Generation Sequencing Panel using Circulating Tumor DNA in Patients with Advanced Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis by Mariana M. Sebastião, Rodrigo S. Ho, João Paulo V. de Carvalho, Micha Nussbaum

“…Therefore, it can be considered a reliable alternative to guide the patients with aNSCLC to the right treatment who cannot undergo an invasive procedure or have insufficient tissue material for molecular tests.…”
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Oncologic oUTcomes of neoadjuvant chemotherapy for obSTructive colon cAncer after steNt decompression (OUTSTAND trial); A study protocol of multicenter non-inferiority randomized controlled trial by Bong-Hyeon Kye, Ji-Hoon Kim, Hyung-Jin Kim, Yoon-Suk Lee, In-Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Jong-Kyung Park, Chang-Hyeok Ahn, Jae-Im Lee, Seong-Taek Oh, Byung Jo Choi

“…Methods & analysis The patients assigned to the control group will undergo curative surgery within two weeks after successful SEMS placement. The patients assigned to the experimental group will undergo three cycles of neoadjuvant FOLFOX chemotherapy within two weeks after successful SEMS placement. …”
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Diagnostic Model of In-Hospital Mortality in Patients with Acute ST-Segment Elevation Myocardial Infarction Used Artificial Intelligence Methods by Yong Li

“…We used confusion matrix combined with the area under the receiver operating characteristic curve (AUC) to evaluate the pros and cons of the above models. …”
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Transcutaneous Bilirubin Measurements Can Be Used to Measure Bilirubin Levels during Phototherapy by Saad Abdullah Alsaedi

“…In this prospective observational study, healthy term newborns who required TSB measurements were included. TcB measurements were taken from the forehead before starting and during phototherapy using the BiliChek device. …”
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The effect of cervical length on procedure time and VAS pain score in office hysteroscopy by Cenk Soysal, Onur Ince, Yasemin Taşçı

“…A cross-sectional study was conducted on 50 patients who underwent office hysteroscopy for various indications such as abnormal uterine bleeding and infertility. …”
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Implications of circular economy practices for firms in the integrated waste sector by Daniel Agyapong, Gloria K. Q. Agyapong, Daniel Ofori, Osman Light, Stephanie Efua Frimpong

“…It was concluded that waste management companies that excel in undertaking circular economy activities such as remanufacturing, trash recycling, and refurbishing are more likely to draw clients who want green activities in addition to their current needs. …”
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Refractive Status in Eyes Implanted with Toric and Nontoric Intraocular Lenses during Combined Cataract Surgery and Microhook Ab Interno Trabeculotomy by Yasuyuki Takai, Kazunobu Sugihara, Mihoko Mochiji, Kaoru Manabe, Aika Tsutsui, Masaki Tanito

“…To compare the refractive status between eyes implanted with toric and nontoric intraocular lenses (IOLs) during combined cataract surgery and microhook ab interno trabeculotomy (μLOT), a minimally invasive glaucoma surgery (MIGS). …”
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Outcomes of Cranioplasty Using Autologous Bone or 3D-Customized Titanium Mesh Following Decompressive Craniectomy for Traumatic Brain Injury: Differences in Complications by Junwon Kim, Jang Hun Kim, Jong Hyun Kim, Taek-Hyun Kwon, Haewon Roh

“…Through a comparative analysis, we aimed to identify differences in complications between the two groups and, using binary logistic analysis, to determine significant factors associated with complications after CP. …”
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National Dialogue: Bahrain Case by E. I. Vulakh

“…In that context both the key task of and the major challenge to the national dialogue is to ensure maximal inclusiveness. In order to do so a few methodological, as well as purely practical questions need to be addressed: interests of what political forces (groups) must be considered, who is to elaborate the criteria and methods of selecting actual participants of the negotiations, how to assess their real representativeness and legitimacy and so on. …”
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Transforaminal Endoscopic Lumbar Discectomy versus Coblation Nucleoplasty Combined with Collagenase Chemonucleolysis for Lumbar Disc Herniation with Grade I Degenerative Spondyloli... by Yuyu Guo, Liuhu Han, Tingting Li, Bingbing Xu, Penghui Ke, Jun Hu, Rongyi Zhang, Yan Guo, Long Zhao, Likui Wang

“…Methods From January 2019 to December 2020, 60 patients who had LDH with grade I degenerative spondylolisthesis were divided into two groups. …”
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Development and predictors of bipolar disorder in children and adolescents with depressive disorders: a systematic review, meta-analysis, and meta-regression by Gonzalo Salazar de Pablo, Violeta Perez-Rodriguez, Javier de Otazu Olivares, Javier Camacho-Rubio, Aditya Sharma, Ana Catalán, Josefien Breedvelt, Claudia Aymerich, Mihai Pop, Carmen Moreno, Ian Kelleher, Jane Anderson, Paolo Fusar-Poli, Christoph U Correll, Allan H. Young

“…Methods In this systematic review and meta-analysis (PROSPERO:CRD42023431301), PubMed and Web-of-Science databases were searched for longitudinal studies reporting the percentage of C&A with ICD/DSM-defined depressive disorders who developed BD during follow-up. …”
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Relationship between Undernutrition and Periodontal Diseases among a Sample of Yemeni Population: A Cross-Sectional Study by Milad Al-Kalisi, Manal Al-Hajri, Sarah Al-Rai

“…A cross-sectional study was conducted at dental teaching clinics at the Faculty of Dentistry, Sana’a University. Of 1920 patients who attended clinics, only 229 matched the study criteria. …”
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Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection among Kidney Transplant Recipients: A Large Single-Center Experience by Emily E. Zona, Mina L. Gibes, Asha S. Jain, Juan S. Danobeitia, Jacqueline Garonzik-Wang, Jeannina A. Smith, Didier A. Mandelbrot, Sandesh Parajuli

“…Methods. We studied all adult KTRs (with a functioning allograft) who had their first episode of SARS-CoV-2 infection between 04/2020 and 04/2022. …”
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Construction of nomogram model based on contrast-enhanced ultrasound parameters to predict the degree of pathological differentiation of hepatocellular carcinoma by Shu-Min Lian, Hong-Jing Cheng, Hong-Jing Li, Hui Wang

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Giant and irregular pituitary neuroendocrine tumors surgery: comparison of simultaneous combined endoscopic endonasal and transcranial and purely endoscopic endonasal surgery at a... by Jun Fu, Wenwei Luo, Chunlin Zhang, Zhicheng Wang, Wenjian Fan, Yuanxiang Lin, Dezhi Kang, Jianping Song, Changzhen Jiang, Xiaorong Yan

“…Methods The data of GIPitNETs patients who underwent surgery between March 2018 and May 2023 at a single center were retrospectively reviewed. …”
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Chronic fatigue and headache in post-COVID-19 syndrome: a radiological and clinical evaluation by Gonçalo G. Almeida, Gonçalo G. Almeida, Saide Alkan, Saide Alkan, Robert Hoepner, André Euler, André Euler, Lara Diem, Franca Wagner

“…This study aimed to investigate the correlation between these symptoms and T2-hyperintense white matter lesions detected on magnetic resonance imaging (MRI) of the brain and spine in patients with post-COVID-19 syndrome.MethodsThis retrospective, single-center study analyzed a sample of 96 patients from Bern University Hospital in Switzerland who presented with suspected post-COVID-19 syndrome between 2020 and 2022. …”
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COVID-19 Recombinant mRNA Vaccines and Serious Ocular Inflammatory Side Effects: Real or Coincidence? by Arash Maleki, Sydney Look-Why, Ambika Manhapra, C. Stephen Foster

“…Abstract Purpose: To report two cases; bilateral arteritic anterior ischemic optic neuropathy (AAION) and bilateral acute zonal occult outer retinopathy (AZOOR) after COVID-19 mRNA vaccination. …”
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