Randomised, pragmatic, waitlist controlled trial of cannabis added to prescription opioid support on opioid dose reduction and pain in adults with chronic non-cancer pain: study pr... by A Eden Evins, Ellie Grossman, Julia Jashinski, Aurora Quaye, Corinne Cather, Kevin Potter, David A Schoenfeld, Jodi M Gilman

“…Also despite lack of efficacy data, there are many reports of people using cannabis products to manage chronic pain and replace or reduce chronic opioids. Here we describe the protocol for a randomised trial of the effect of cannabis, when added to a behavioural pain management and prescription opioid taper support programme, on opioid utilisation, pain intensity and pain interference.Methods This is a pragmatic, single-blind, randomised, wait-list controlled trial that aims to enrol 250 adults taking prescription opioids at stable doses of ≥25 morphine milligram equivalents per day for chronic non-cancer pain who express interest in using cannabis to reduce their pain, their opioid dose or both. …”
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Impact of leadless pacemaker implantation site on cardiac synchronization and tricuspid regurgitation by Xiao-fei Gao, Hong Zhu, Jia-sheng Zhang, Ning-Zhang, Xiao-hong Pan, Yi-Zhou Xu

“…Post-pacing QRS duration showed no significant difference between the two groups (139.21 ± 11.36 vs. 143.83 ± 16.35 ms P = 0.310). …”
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Osteoradionecrosis in osseous free flaps after maxillofacial reconstruction: a single-center experience by Jakob Fenske, Philipp Lampert, Eirini Nikolaidou, Claudius Steffen, Marcus Beck, Norbert Neckel, Susanne Nahles, Max Heiland, Friedrich Mrosk, Steffen Koerdt, Carsten Rendenbach

“…This study aims to evaluate the therapeutic outcomes and potential predictors of free flap ORN within osseous free flaps based on a large-scale, single-center database.MethodsA retrospective analysis was conducted on patients who underwent osseous free flap reconstruction of maxilla or mandible in a one stage procedure followed by adjuvant radiotherapy due to an advanced head and neck malignancy between April 2017 and July 2023. …”
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Classification of Wheezing Children in Rural Bangladesh by Intensity of Ascaris Infection, Total and Specific IgE Levels, History of Pneumonia, and Other Risk Factors by Haruko Takeuchi, Md Alfazal Khan, Khalequz Zaman, Sayaka Takanashi, S. M. Tafsir Hasan, Mohammad Yunus, Tsutomu Iwata

“…We analyzed relevant data collected in 2001. The participants included 219 5-year-old wheezing children who were randomly selected from 1705 children living in the Matlab Health and Demographic Surveillance area of the International Centre for Diarrhoeal Disease Research, Bangladesh. …”
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Navigating the Risk Landscape in ST-Elevation Myocardial Infarction Patients Postpercutaneous Coronary Intervention: A Narrative Review by Utkarsh Gaur, Charuta Gadkari, Aditya Pundkar

“…All these factors together create a complex, high-risk profile of patients who will need individualised and directed management strategies for optimum reduction in mortality. …”
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Political technologies: structural and functional indifference by O. N. Zabuzov

“…These examples show the functional indifference of political technologies.The functional indifference of political technologies has been shown: in terms of their content, structure and functions, political technologies are "indifferent" to the political process, to the person who uses them.…”
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Prior Appendectomy and the Onset and Course of Crohn’s Disease in Chinese Patients by Dafan Chen, Jing Ma, Qiwen Ben, Lungen Lu, Xinjian Wan

“…A retrospective case-control study was performed to compare prior appendectomy rate between CD patients and age- and gender-matched controls at two Chinese hospitals. The clinical course of CD was determined in patients who underwent and did not undergo appendectomies before CD diagnosis. …”
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Suicidal ideation and its associated risk factors among students of a medical college in Chennai—A cross-sectional study by M Koushik, Prarthana Veeramani, L Pooja Mary Vaishali, B Charumathi, Timsi Jain

“…Previous studies have analyzed suicidal ideation in patients who have already attempted self-harm. In this study, we aim to find out the prevalence of suicidal ideation and knowledge of danger signs of suicide in a nonclinical population, especially among students of a medical college. …”
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Environmental Sustainability, Value Re-Orientation as Panacea to Gender-Based Violence and Culture of Silence Among Adolescent Girls by Florence Adeoti Yusuf, Adesile Moshood Imran, Peter Sanjo Adewale

“…Community leaders should implement community-based interventions, such as locking up or imprisoning those who have committed any type of GBV inside their community. …”
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Outcomes of Hospitalized COVID-19 Patients by Risk Factors: Results from a United States Hospital Claims Database by Peter J. Mallow, Kathy W. Belk, Michael Topmiller, Edmond A. Hooker

“…**Conclusions:** Quantifying the role of CDC risk factors upon admission may improve risk stratification and identification of patients who may require closer monitoring and more intensive treatment.…”
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Improving health outcomes by strengthening public sector capacity in social and behaviour change programming in Nigeria: a qualitative study by Pooja Sripad, Augustine Ankomah, Amanda Kalamar, Adetayo Adetunji, Bright Addo, Dele Abegunde, Nrupa Jani Tulsiani, Foyeke Oyedokun-Adegbabo

“…At the organisational level, the approach facilitated coordination of SBC activities, enabled training cascades and promoted adherence to health service guidelines. …”
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Lenvatinib versus sorafenib as second-line therapy following progression on atezolizumab–bevacizumab in patients with unresectable hepatocellular carcinoma: a multicenter retrospec... by Jaekyung Cheon, Shigeo Shimose, Hyung-Don Kim, Takashi Niizeki, Min-Hee Ryu, Tomotake Shirono, Baek-Yeol Ryoo, Hideki Iwamoto, Changhoon Yoo

“…However, the optimal second-line treatment for patients unresponsive to AB remains undefined. Patients and methods This multicenter, retrospective study included patients with uHCC who underwent second-line treatment with lenvatinib (LEN) or sorafenib (SOR) after AB failure at two academic centers between June 2018 and November 2023. …”
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Evaluating The Effectiveness Of Near-Peer Teaching Modality In Undergraduate Dental Students Learning A Psychomotor Skill (Partial Denture Fabrication) Considering Social And Cogni... by Saima Irshad, Gulmina Saeed Orakzai, Waqar-Un Nisa, Nauman Bari Khan, Misbah Ali, Saba Farooq

“… Objective: To analyze the effectiveness of Near Peer Teaching (NPT) modality in the psychomotor skills development of dental students in fabricating removable partial dentures considering cognitive and social congruence factors Methods: This sequential two-phase experimental study was carried out from September 2022- December 2022 at Watim Dental College Rawalpindi. 50 Students of second-year BDS and recently graduated dental interns who were doing House jobs participated in the study. 50 students were divided into 2 groups A and B respectively. …”
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Nutrition Knowledge and Satisfaction Levels of Postbariatric Surgery Adults in the United Arab Emirates: A Pilot Study by Souheir Alia, Habiba I. Ali, Taoufik Zoubeidi, Mariam Ahmed

“…Research assessing the nutrition knowledge of postbariatric surgery patients is limited, although this category of patients is predisposed to malnutrition. In this pilot study, we explored postbariatric nutrition knowledge, satisfaction levels with dietitian nutrition counseling, and decision to undergo bariatric surgery of 83 patients who attended a postbariatric outpatient nutrition clinic in Dubai, United Arab Emirates (UAE). …”
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Legal basis for providing legal aid to a detained person in the context of international standards and practice of the European Court of Human Rights by M. М. Kolomoitsev

“…Based on the analysis of theoretical approaches to the essence of the institute of detention of a person, the article substantiates the position that detention is a procedural action which has a temporary restrictive nature of the rights of a person who was detained during the commission or attempted commission of a criminal offence, immediately after the commission of a criminal offence or during the continuous prosecution of a person suspected of a criminal offence, and which aims to ensure further pre-trial investigation, clarification of the circumstances of the event which occurred. …”
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Effect of Different Doses of Sugammadex on Recovery and Hemodynamic Parameters in Reversing Neuromuscular Blockade in Patients Undergoing Electroconvulsive Therapy by Kadir ARSLAN, Gozde UCUKSARAC, Hale CETIN ARSLAN, Erkan AYDIN, Ayca Sultan SAHIN

“…The most common diagnosis (32.7%) in patients who underwent ECT was bipolar disorder. The average time to recovery of spontaneous breathing, eye-opening time, time to comply with voluntary commands, and time to reach MAS 9 were found to be significantly lower in group 3 (p<0.001, p<0.001, p<0.001, and p=0.002, respectively). …”
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Stem cell markers: A guide to neoadjuvant therapy in breast carcinomas by Zuhal Gucin, Nur Buyukpinarbasili, Melin Ozgun Gecer, Yeliz Emine Ersoy, Haci Mehmet Turk, Seyma Yildiz, Direnc Ozlem Aksoy

“…Statistical Analysis Used: IBM Statistical Package for the Social Sciences (SPSS), version 23.0 (IBM Corp., Armonk, NY, USA) software was used for statistical analyses, and a P value less than 0.05 was considered statistically significant. …”
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A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass by Sarahi Herrera-Gonzalez, Dema Shamoon, Tingliang Shen, Simon Badin, Yatinder Bains

“…Treatment involves conventional chemo-immunotherapy consisting of R CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) or RB (rituximab and bendamustine), with the latter being better tolerated and associated with longer progression-free survival. …”
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Sedated and unsedated gastroscopy has no influence on the outcomes of patients with gastric cancer: a retrospective study by Chengke Yin, Yiwu Sun, Jie Liang, Xin Sui, Zhaoyi He, Ailing Song, Wenjia Xu, Lei Zhang, Yufei Sun, Jingshun Zhao, Fei Han

“…Methods This was a retrospective study of patients who were diagnosed with GC by gastroscopy and underwent gastrectomy from January 2013 to December 2017. …”
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Effect of Intestinal Levodopa-Carbidopa Infusion on Pharyngeal Dysphagia: Results from a Retrospective Pilot Study in Patients with Parkinson’s Disease by Bendix Labeit, Inga Claus, Paul Muhle, Sonja Suntrup-Krueger, Rainer Dziewas, Tobias Warnecke

“…In all patients with PDrPD who underwent flexible endoscopic evaluation of swallowing (FEES) in the clinical “on-state” both before and after implementation of LCIG treatment, FEES videos were systematically reassessed. …”
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