Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR by Zhongxia Wang, Tao Zhang, Lizhe Sun, Ruifeng Li, Yuanyuan Wei, Xiaojuan Fan, Zuyi Yuan, Junhui Liu, Tao Chen

“…DES-induced mRNA expressions of IL-6, TNF-α, and MMP-9 in circulating MNC were significantly blocked by PIO (P=0.031, 0.012, and 0.007, resp.). In addition, PIO markedly inhibited DES-enhanced NF-κB function and DES-blocked PPAR-γ activity. …”
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Medullary breast carcinoma: a pathogenic review and immunohistochemical study using tissue microarray by Ming Lee, Ana Richelia Jara-Lazaro, Poh Yian Cheok, Aye Aye Thike

“…Results: Using Ridolfi’s criteria for histologic reviews, 62 patients previously diagnosed as having ‘typical MBC’ (n = 26), ‘atypical MBC’ (n = 32) and ‘invasive carcinoma with focal medullary-like features’ (n = 4) were re-classified as follows: ‘typical MBC’ (n = 6; 9.7%), ‘atypical MBC’ (n = 46; 74.2%), and ‘non-medullary infiltrating carcinoma’ (n = 10; 16.1%). …”
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Exploring perceptions of medical students about interprofessional education (IPE): a qualitative study by Ying Xing, Chengrui Zhang, Tao Jin, Wei Luan

“…Methods A descriptive qualitative study was conducted in 2023, using purposive sampling to select medical students who had interprofessional learning experiences for semi-structured interviews. …”
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Intranasal racemic ketamine maintenance therapy for patients with treatment-resistant depression: a naturalistic feasibility study by Katelyn Halpape, Raelle Pashovitz, Annabelle Wanson, Monika Hooper, Evyn M. Peters

“…Participants were adult inpatients with treatment-resistant depression who had been successfully treated with intranasal racemic ketamine in hospital and were being referred for outpatient maintenance therapy with an intranasal racemic ketamine spray, administered at a specialized community treatment centre. …”
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Does therapy with immunosuppressive drugs improve gastrointestinal symptoms in patients with systemic sclerosis? by Oliver Distler, Cosimo Bruni, Suzana Jordan, Carina Mihai, Muriel Elhai, Rucsandra Dobrota, Alexandru Garaiman, Mike Oliver Becker, Lea Stamm, Sherif Ismail, Norina Zampatti, Aurora Maria Tatu

“…Objectives While important progress was made regarding the treatment of systemic sclerosis (SSc), there is still no evidence-based disease-modifying treatment available for SSc-related gastrointestinal (GI) manifestations. We aimed to identify an association between immunosuppressive therapy and the the severity of GI symptoms, measured by the University of California at Los Angeles/Scleroderma Clinical Trial Consortium Gastro-Intestinal Tract instrument 2.0 (GIT).Methods We selected patients with SSc who had at least two visits (further referred to as ‘baseline’ and ‘follow-up’) with completed GITs, within an interval of 12±3 months. …”
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Ibuprofen-Induced Multiple Fixed Drug Eruption Confirmed by Re-Challenge: A Case Report and Literature Review by Yoshihito Mima, Masako Yamamoto, Hiyo Obikane, Yuta Norimatsu, Ken Iozumi

“…In FDE, effector memory CD8-positive T cells that remain dormant in the basal layer after a previous inflammation are reactivated upon re-exposure to the causative drug, leading to the development of erythema at the same sites. <b>Case Presentation:</b> Herein, we report the case of a 23-year-old man who developed ibuprofen-induced multiple FDE. …”
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Assessment of factors implicated in bone fusion after percutaneous endoscopic lumbar intervertebral fusion by Zheng Huang, Xialin Li, Weihong Yi, Junfeng Gong, Yue Zhou, Yu Tang

“…Methods: This single-center retrospective study reviewed the medical records of 96 patients who underwent single-level PELIF for degenerative pathologies between 2018 and 2020. …”
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1-year data on patient-reported outcome is enough after surgery for degenerative cervical myelopathy: a cohort study from the Swedish Spine register by Lovisa Gerdhem, Anna MacDowall, Paul Gerdhem

“…Results: 642 individuals had baseline, 1-, and 2-year follow-up data, of whom 347 also had 5-year data. EMS was 14 (12–16) preoperative, 15 (12–17) at the 1-year follow-up, and 15 (12–17) at the 2-year follow-up. …”
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High‐risk cytogenetic abnormalities in multiple myeloma: PETHEMA‐GEM experience by Veronica González‐Calle, Paula Rodriguez‐Otero, Maria J. Calasanz, Manuela Guijarro, Joaquin Martínez‐López, Laura Rosiñol, Miguel T. Hernández, Ana I. Teruel, Mercedes Gironella, Albert Oriol, Javier de laRubia, Ana P. González‐Rodríguez, Joan Bargay, Felipe deArriba, Luis Palomera, Marta‐Sonia González‐Pérez, Anna Sureda, Enrique Ocio, Juan J. Lahuerta, Joan Bladé, Jesus F. San Miguel, Maria V. Mateos, Norma C. Gutiérrez

“…Abstract This study examines the impact of cytogenetic abnormalities and their co‐segregation on the prognosis of newly diagnosed multiple myeloma patients. …”
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Effectiveness of Traditional Healers in Program to Control Leprosy in Nagan Raya District in Aceh by Teuku Alamsyah, Said Usman, Mutia Yusuf, Said Devi Elvin

“…Nagan Raya was the District in Aceh with the highest number of cases; new cases in 2015 comprised 26 with Paucibacillary (PB) and 21 with Multibacillary (MB) with a total of 4.26% with Grade II disability. …”
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The Feasibility and Safety of the Clip-and-Snare Method with a Prelooping Technique for Gastric Submucosal Tumors Removal: A Single-Center Experience (with Video) by Qi Tang, Rui-Yue Shi, Jun Yao, Li-Sheng Wang, De-Feng Li

“…This study compared the efficacy and safety of endoscopic submucosal dissection (ESD) combined with clip-and-snare method and a prelooping technique (CSM-PLT) with ESD alone for the treatment of gastric submucosal tumors (gSMTs). Methods. We retrospectively enrolled a matched group of 86 patients who received ESD combined with CSM-PLT or ESD alone from July 2010 to July 2020. …”
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Multimodal Imaging Characteristics of ADRP in a Family with p.Thr58Arg Substituted RHO Mutation by Misty Ruppert, John Pyun, K. V. Chalam, David Sierpina

“…Additionally, we compare the patient’s phenotypic findings to those of her offspring, who was also affected by adRP. …”
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Determining barriers and facilitators to engagement for families in a family-based, multicomponent healthy lifestyles intervention for children and adolescents: a qualitative study by Yvonne C Anderson, Paul L Hofman, Cervantée EK Wild, Ngauru T Rawiri, Esther J Willing

“…Semistructured, home-based interviews were conducted and thematically analysed with peer debriefing for validity.Participants Families were selected through stratified random sampling to include a range of levels of engagement, including those who declined their referral, with equal numbers of interviews with Indigenous and non-Indigenous families.Results Three interactive and compounding determinants were identified as influencing engagement in Whānau Pakari: acute and chronic life stressors, societal norms of weight and body size and historical experiences of healthcare. …”
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Use Of Anti-Epileptics For Seizure Prophylaxis After Traumatic Brain Injury In The Pediatric Population by Aroosh Khan, Sidra Tul Muntaha, Hammad Ayaz, Afrah Tariq, Huma Mughal

“…A total of 160 children aged from 2 to 18 years who presented with traumatic brain injury within 24 hours of trauma were included. …”
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Hermann Karl von Keyserlingk and the Recognition of the Russian Imperial Title by the Holy Roman Empire in 1745–1746 by M. A. Petrova

“…The author managed to find out, it was Keyserlingk who had the idea to send the official representative of Russia to the election of the Emperor in Frankfurt in 1745 and then in 1746 to the Imperial Diet in Regensburg, which approved the election results. …”
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Association between Bioelectrical Impedance Parameters, Magnetic Resonance Imaging Muscle Parameters, and Fatty Liver Severity in Children and Adolescents by Kyungchul Song, Eun Gyung Seol, Eunju Lee, Hye Sun Lee, Hana Lee, Hyun Wook Chae, Hyun Joo Shin

“…Methods: Children and adolescents who underwent BIA and liver magnetic resonance imaging between September 2022 and November 2023 were included. …”
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Une famille transatlantique : les Fleuriau by Jacques de Cauna

“…The character of Aimé-Benjamin Fleuriau, plantation owner on the island of Saint-Domingue, born of a protestant family of La Rochelle, France, has become a true legend in his native town since a Ph.D. dissertation was devoted to him in 1982.It is, however, the issue of racial mixing [métissage], through one of the Domingan sons of his « housekeeper » [ménagère], which has recently inspired a novel rewarded with the Prix Renaudot, and then his whole « colored » family which has just been the object of a new Ph.D. at the university of Michigan. We can clearly see today, through the new context of cultural studies, how French families dealt with colonial contingencies characterized in particular by the presence of Blacks and free men of color in La Rochelle (he brought back with him two of his daughters of color and gave plantations and slaves to his sons of color who stayed back in Saint-Domingue) with an undeniable flexibility in the adaptation of their traditional strategies regarding kinship, marriage, godparents, and inheritance.The family of La Rochelle is in a way remodelled in the light of the Domingan slave society, but still seeking to preserve the interests of its members. …”
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Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India by Deepak Menon, Manisha Gupta, Sangeeth Thuppanattumadam Ananthasubramanian, Karthik Kulanthaivelu, Pritam Raja, Subasree Ramakrishnan, Sangeetha Seshagiri Karnam, Jitender Saini, PR Srijithesh, Girish B Kulkarni

“…Background and Objectives: Early initiation and maintenance of anticoagulation appears to be the mainstay of treatment of cerebral venous thrombosis (CVT), but the evidence supporting the intensity and duration of anticoagulation is limited. Methods: We retrospectively collected data of patients admitted with CVT over a 5-year period, who had a minimum of 6 months of clinical follow-up and three or more prothrombin time international normalized ratio (INR) values spread over 6 months. …”
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A Nomogram Based on Apelin-12 for the Prediction of Major Adverse Cardiovascular Events after Percutaneous Coronary Intervention among Patients with ST-Segment Elevation Myocardial... by Enfa Zhao, Hang Xie, Yushun Zhang

“…Information on 464 patients with STEMI who performed PCI procedures was included. After removing patients with incomplete clinical information, a total of 460 patients followed for 2.5 years were randomly divided into evaluation (n = 324) and validation (n = 136) cohorts. …”
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A Study of Hypothyroidism in Chronic Kidney Disease (CKD) Patients by Sudharsanan V, Prabhu Shankar S, Viknesh V

“…The study involved 237 CKD patients who provided informed consent and met inclusion criteria. …”
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