Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3β Pathway by Zheng S, Xie Z, Zhou Z, Wang S, Xin Y, Lin J, Cheng K, Lu T, Qi R, Guo Y

“…Prior studies showed Platycodin D (PD)-induced cell cycle arrest and apoptosis in NSCLC via RNA regulatory network, yet elucidating PD’s mechanisms in NSCLC progression is challenging in the real world.Methods: Biological effects of PD on NSCLC cell lines A549 and PC-9 were assessed through in vitro assays, encompassing apoptosis, proliferation, colony formation, migration and invasion. …”
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In Vitro Activities of Ceftobiprole and Doripenem Tested against Frequently Encountered Aerobic and Facultative Gram-Positive and Gram-Negative Bacterial Pathogens Isolated from Pa... by James A Karlowsky, Mel DeCorby, Daryl J Hoban, George G Zhanel

“…OBJECTIVES: To determine the in vitro activities of ceftobiprole and doripenem using a collection of frequently isolated aerobic and facultative bacteria cultured from patient blood, urine, respiratory and wound specimens in 12 Canadian hospitals in 2007. …”
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The science and politics of ‘knowledge’ in safe sport research by Benjamin Carr

“…., more than 80% of the items were ‘double-barrelled’), most of which would tend towards over-reporting cases of violence. …”
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Comparison of Functioning, Quality of Life, and Cognition between Lithium and Sodium Valproate Combination Therapy and Sodium Valproate Monotherapy in Euthymic Bipolar Patients: A... by M Ashwini, R Jhamuna, V Jaikumar

“…The Global Assessment of Functioning (GAF) scale and the World Health Organisation Quality of Life Brief (WHOQoL-BREF) version scale were applied to both groups. …”
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Repetitive Transcranial Magnetic Stimulation for the Treatment of Complex Regional Pain Syndrome: A Pilot Study by Foglia SD, Drapeau CC, Ramdeo KR, Adams FC, Soppitt DB, Rehsi RS, Shanthanna H, Nelson AJ

“…Stevie D Foglia,1 Chloe C Drapeau,2 Karishma R Ramdeo,2 Faith C Adams,2 Daniel B Soppitt,2 Ravjot S Rehsi,2 Harsha Shanthanna,1,3 Aimee J Nelson1,2 1School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada; 2Department of Kinesiology, McMaster University, Hamilton, ON, Canada; 3Department of Anesthesia, McMaster University, Hamilton, ON, CanadaCorrespondence: Aimee J Nelson, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada, Tel +1 905-525-9140 x28053, Fax +1 905-523-6011, Email nelsonaj@mcmaster.caPurpose: Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition characterized by sensory, motor, and autonomic dysfunction with a world-wide prevalence of 26.2 per 100,000 people per year and is 3 to 4 times more prevalent in females. …”
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A Problem of Perspective: Religions in Africa or African Traditional Religion by Osman Şahin

“…Information about African religions was first provided in the works written mostly by Westerners. The works written by Christian missionaries, anthropologists, soldiers and researchers on religious life in Africa, both before and after the colonial period, have been the trendsetters of the "religion in Africa" literature. …”
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To what extent does the CO₂ diurnal cycle impact flux estimates derived from global and regional inversions? by S. Munassar, S. Munassar, S. Munassar, C. Rödenbeck, M. Gałkowski, M. Gałkowski, F.-T. Koch, F.-T. Koch, K. U. Totsche, K. U. Totsche, S. Botía, C. Gerbig

“…Differences between CO<span class="inline-formula">₂</span> mixing ratios simulated with daily averaged and hourly NEE from FLUXCOM-X range between around <span class="inline-formula">−</span>2.5 and 7 ppm averaged annually throughout a site network across the world. These differences lead to systematic biases in CO<span class="inline-formula">₂</span> flux estimates from the atmospheric inversions. …”
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Modulation of Acupuncture at Quchi (LI 11) and Waiguan (SJ 5) acupoints on LTP-like Plasticity by Qianqian SUN, Guo YU, Huitian ZHANG, Xiaokuo HE

“…We used three laser pens to locate and mark with a soft-tipped pen to assure a constant placement of the coil throughout the session.②Detection of resting motor threshold (rMT): The response resting motor threshold (rMT) was defined as the stimulus intensity at which 5/10 consecutive single stimuli at the optimal sclap site evoked a MEP of at least 50 μV amplitude in the relaxed muscle.③Investigate the short-latency somatosensory-evoked potentials (SLSEP): Monophasic electrical stimulation adjusted to produce visible thumb twitch was delivered at points overlying the ulnar nerve at the right of FDI, through a bipolar electrode (cathode proximal) with intensity 5-10 mA.④Brain plasticity induced by PAS-LTP: The LTP-like plasticity induced by paired associative stimulation (PAS) consisted of 200 stimulus pairs of electrical stimulation followed by TMS. Subjects would be tested 8 times for about 80 minutes each time. …”
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A Digital Tool (Technology-Assisted Problem Management Plus) for Lay Health Workers to Address Common Mental Health Disorders: Co-production and Usability Study in Pakistan by Maham Saleem, Shamsa Zafar, Thomas Klein, Markus Koesters, Adnan Bashir, Daniela C Fuhr, Siham Sikander, Hajo Zeeb

“…Stage 1 (evidence review and stakeholder consultation) included 3 focus group discussions with 32 LHWs and 7 in-depth interviews with key stakeholders working in the health system or at the health policy level. …”
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Proximal Hamstring Tendinopathy: A Systematic Review of Interventions by Anthony Michael Nasser, Bill Vicenzino, Alison Grimaldi, Jay Anderson, Adam Ivan Semciw

“… # Conclusions There is insufficient evidence to recommend any one intervention over another. A pragmatic approach would be to initially trial approaches proven successful in other tendinopathies…”
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Analisis Sentimen terhadap Kebijakan Kuliah Daring Selama Pandemi Menggunakan Pendekatan Lexicon Based Features dan Support Vector Machine by Natasya Eldha Oktaviana, Yuita Arum Sari, Indriati Indriati

“…Abstract The existence of a new virus, namely COVID-19 or SARS-CoV-2, that come from Wuhan, China, in early 2020, has shocked all citizens of the world, including Indonesia, and has a high transmission rate. …”
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Paesaggi della memoria della Grande Guerra (1914-1918) Un cambiamento paradigmatico nella ricerca turistica sull’heritage di guerra by Myriam Jansen-Verbeke, Wanda George

“…Il valore aggiunto di una survey internazionale online, completata dal World Heritage Tourism Research Network1 (WHTRN) nel 2012, riguarda sia l’approccio concettuale e interdisciplinare, che ha indagato l’interdipendenza dei processi culturali, sociali, economici e politici nel contesto dei paesaggi della memoria di Guerra, sia i dati empirici che risultano da questa analisi multilinguistica.Emergono nuovi paesaggi turistici, nei quali giocano un ruolo importante gli interessi dei governi nazionali e regionali e degli stakeholders locali e internazionali. …”
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Comprehensive overview of genotype distribution and prevalence of human papillomavirus in cervical lesions by Yang Liu, Chengquan Zhao, Tiannan Wang, Yuhong Ye, Terrel Jones, Xianxu Zeng

“…Continual advancements in clinical guidelines integrating extended genotyping would increase diagnostic accuracy and refine strategies in clinical management.…”
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Profiling Key Phytoconstituents in Screw-Pressed <i>Nigella</i> Solid Residue and Their Distribution in Products and Byproducts During Oil Processing by Parbat Raj Thani, Joel B. Johnson, Surya Bhattarai, Tieneke Trotter, Kerry Walsh, Daniel Broszczak, Mani Naiker

“…However, extracting oil to satisfy the world’s needs leaves behind plenty of solid residues. …”
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Use of Go-Beyond as a Self-Directed Internet-Based Program Supporting Veterans’ Transition to Civilian Life: Preliminary Usability Study by Karolina Katarzyna Alichniewicz, Sarah Hampton, Madeline Romaniuk, Darcy Bennett, Camila Guindalini

“…Notably, 94% (88/94) of survey respondents indicated they would recommend the program to other veterans, family, or friends. …”
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Clozapine for Treatment-Resistant Disruptive Behaviors in Youths With Autism Spectrum Disorder Aged 10-17 Years: Protocol for an Open-Label Trial by André Luiz Schuh Teixeira da Rosa, Marina Ribeiro Barreto da Costa, Gabriela Bezerra Sorato, Felipe de Moura Manjabosco, Érica Bonganhi de Bem, Lucas Dellazari, Arthur Bezerra Falcão, Lucas de Oliveira Cia, Olivia Sorato Bezerra, Rogério Boff Borges, Luis Augusto Rohde, Ana Soledade Graeff-Martins

“…Adopting a pragmatic approach, this trial protocol aims to mirror real-world clinical settings, thereby enhancing the applicability and relevance of our findings. …”
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Abyssinian pea (Lathyrus schaeferi Kosterin nom. nov. pro Pisum abyssinicum A. Br.) is a problematic taxon by O. E. Kosterin

“…Br.) Berger. Perhaps it would be most correct to consider it as a hybridogenic species. …”
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Lentivirus‐mediated gene therapy for Fabry disease: 5‐year End‐of‐Study results from the Canadian FACTs trial by Aneal Khan, Dwayne L. Barber, William M. McKillop, C. Anthony Rupar, Christiane Auray‐Blais, Graeme Fraser, Daniel H. Fowler, Alexandra Berger, Ronan Foley, Armand Keating, Michael L. West, Jeffrey A. Medin

“…Interim results from this ‘first‐in‐the‐world’ Canadian FACTs (Fabry Disease Clinical Research and Therapeutics) trial were published in 2021. …”
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An efficient method for predicting the morphology of proppant packs based on a surrogate model by Tao ZHANG, Hangyu ZHOU, Yifan ZHANG, Jianchun GUO, Haoran GOU, Tang TANG

“…The numerical simulation results of proppant transport would be adopted as data sets for input, training, and testing. …”
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Evaluation of the adherence of municipalities and states to the Ministry of Health’s microplanning for high-quality vaccination activities and the increase in vaccination coverage... by Ana Catarina de Melo Araújo, Thales Philipe Rodrigues da Silva, Gustavo Velasquez-Melendez, Luciana Maiara Diogo Nascimento, Carla Conceição Ferraz, Fernanda Penido Matozinhos, Eder Gatti Fernandes

“…Abstract Background Immunization is a significant public health achievement for the whole world, although the population’s adherence to vaccination efforts remains a concern. …”
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