ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…However, its role across different cancer types is not well understood.MethodsUtilizing multi-omics data, we comprehensively evaluated ITGA4’s expression, clinical relevance, diagnostic and prognostic value, functions, mutations, and methylation status, along with its impact on immunity, mismatch repair (MMR), heterogeneity, stemness, immunotherapy responsiveness, and drug resistance in pan-cancer, with partial validation in gastric cancer (GC) using transcriptomic analysis, single-cell data, western blot (WB), wound-healing assay, flow cytometry and immunohistochemistry (IHC). …”
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The Neglected Creatures of Forests: Wild Bees by Yasemin Güler

“…Although honey bee (Apis mellifera L.) is the best known as pollinator and most common species in ecosystems, there are approximately 16.000 bee species all over the world that have been described so far. The importance of the presence of bees in all ecosystems, including forests, will be more clearly understood when approximately 80% of flowering plants are thought to be pollinated by animals. …”
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Cloud-edge hybrid deep learning framework for scalable IoT resource optimization by Umesh Kumar Lilhore, Sarita Simaiya, Yogesh Kumar Sharma, Anjani Kumar Rai, S. M. Padmaja, Khan Vajid Nabilal, Vimal Kumar, Roobaea Alroobaea, Hamed Alsufyani

“…Simulations using real-world IoT data on the iFogSim platform showed significant improvements: task scheduling time was reduced by 21%, operational costs by 17%, and energy consumption by 22%. …”
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The Role of Higher Education Through the Eyes of Hungarian Undergraduate Students and Graduates: A Qualitative Exploratory Study by Zsófia Kocsis, Gabriella Pusztai

“… Context: Most education systems equip graduates with the professional knowledge and cognitive skills needed to enter the world of work. However, there are other competencies also important for young graduates to become successful employees. …”
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Hikaya as a literary genre (based on A. Eniki's literary works of the 1940s–1960s) by V.R. Amineva

“…On the basis of the study the following conclusions have been made: the specifics of hikaya genre in A. Eniki's works define the correlation of epic and lyrical categories in the structure of the work. …”
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Hydrogeochemical characterization of groundwater using water quality index and multivariate statistical analysis in Binji town and environs, Sokoto basin, Northwestern Nigeria by Ibrahim Mohammed Abdullahi, Lawali Abubakar, Garba Saidu, Hassan Yusuf

“…Ca ion exceeded the Nigerian standard for drinking water quality (NSDWQ) and the World Health Organization (WHO) set limits in one sample, Mg in 14 samples while K exceeded in four samples. …”
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The Effect of Exercise-Induced Central Fatigue on Cervical Spine Joint Position Error, Strength, and Endurance by Antonio Vintimilla, Troy Hooper, C. Roger James, Ho Cheng Lu, Karthick Natesan, Jeegisha Kapila, Phil Sizer

“…The investigators hypothesized that EICF would have a negative effect on all variables. # Study Design Healthy subjects were examined using a single factor, within-subjects repeated measures design. …”
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Relationship Between Weight Status and Health-Related Quality of Life in School-age Children in China by Mandana Zanganeh, Peymané Adab, Bai Li, Miranda Pallan, Wei J. Liu, Lin Rong, Wei Liu, James Martin, Kar K. Cheng, Emma Frew

“…Height and weight measures were taken at school by trained researchers using standardized methods, and BMI _z_ scores were calculated using the World Health Organization 2007 growth charts. The relationship between HRQOL and weight status was examined using multivariable analyses, adjusting for age, gender, and socioeconomic status. …”
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Quality assessment and umbrella review of systematic reviews about dance for people with Parkinson's disease. by Camila Pinto, Rafaela Simon Myra, Alexandre Severo do Pinho, Francisca Pereira, Guido Orgs, Aline Souza Pagnussat

“…<h4>Objective(s)</h4>To determine (1) the quality of systematic reviews about dance-based intervention in individuals with Parkinson's disease (PD) and (2) standard evidence for dance-based intervention efficacy based on the categories of The International Classification of Functioning, Disability, and Health (ICF) from the World Health Organization's (WHO).<h4>Methods</h4>The data source included MEDLINE, PUBMED, Embase, Scopus, CENTRAL (Cochrane Library), CINAHL, PEDro, SPORTDiscus, APA PsycNet (APA PsycINFO), LILACS, SciELO, and AMED. …”
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Institutional structure formation of the global green finance market by A. S. Issenov

“…Using the global green bond market as an example, up-to-date statistics and analysis of the broader composition of issuers of green financial instruments by country, world region, sovereign and corporate participants, and development institutions have been presented. …”
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Renewal of wheat cultivars enhances ozone resistance in yield but detrimentally impacts quality: a survey of Chinese wheat by Yinsen Qian, Zheng Zhao, Yifan Cao, Quan Ma, Nanyan Zhu, Lingqi Song, Min Zhu, Min Zhu, Chunyan Li, Chunyan Li, Jinfeng Ding, Jinfeng Ding, Wenshan Guo, Wenshan Guo, Xinkai Zhu, Xinkai Zhu, Xinkai Zhu

“…With China being the leading wheat producer of the world, contributing 17.8% to global output, the vulnerability of wheat to O3 is of particular concern. …”
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Digital Health Intervention (SANGYAN Podcast) to Enhance Knowledge Related to COVID-19 and Other Health Conditions: Protocol for an Implementation and Evaluation Study by Ashish Joshi, Surapaneni Krishna Mohan, Apurva Kumar Pandya, Ashoo Grover, Sofia Rani Saggu, Saravanavel Kalpana Revathi, Shruti Sharma

“…ConclusionsThe finding from this research project will aid in the development and implementation of data-driven, evidence-based, and human-centered behavior change interventions using podcasts to address public health challenges among populations living in diverse settings. This would also help in enhancing the acceptability of podcasts as a source of health-related information. …”
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Differences in effects of varying compound extreme temperature and precipitation events on summer maize yield in North China by Zhongxian Liu, Rangjian Qiu, Qi Zhang

“…With global climate change, compound extreme weather events are occurring more frequently in many parts of the world. Air temperature and precipitation are the most important weather elements that influence maize growth and yield formation, especially under rainfed cultivation. …”
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Assessing gut barrier integrity and reproductive performance following pre-mating oral administration of solid-lipid-nanoparticles designed for drug delivery by Valentina Lacconi, Valentina Lacconi, Micol Massimiani, Micol Massimiani, Giulia Antonello, Paolo Gasco, Roberta Bernardini, Cristiana Ferrari, Lorenzo Ippoliti, Gina La Sala, Antonio Pietroiusti, Ivana Fenoglio, Chiara Riganti, Luisa Campagnolo

“…Considering that assumption of drug-delivering nanocarriers in reproductive age may potentially affect women’s reproductive health, the aim of the present study was to evaluate whether repeated oral administration of SLNs to female mice prior to mating would influence key pregnancy outcomes. For this purpose, SLNs melatonin loaded (SLN + mlt) or unloaded were orally administered to CD1 female mice at two different dosages—low (7.5 mg/kg) and high (750 mg/kg) —three times a week for 6 weeks. …”
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Predicting positive Clostridioides difficile test results using large-scale longitudinal data of demographics and medication history by Anh Pham, Robert El-Kareh, Frank Myers, Lucila Ohno-Machado, Tsung-Ting Kuo

“…Decision boundary analysis was conducted using pair-wise false positive and false negative cases each model would predict at a specific threshold. Results: Logistic Regression, Random Forest, and Ensemble models yielded test AUROCs of 0.839, 0.851, and 0.866, respectively. …”
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Stover yield, morphological fractions and nutrient composition of five stay-green sorghum (Sorghum biochar L.) varieties at the physiological maturity stage by Abuye Tulu, Mekonnen Diribsa, Birmeduma Gadisa, Worku Temesgen

“…In contrast, Asosa1 yielded the highest leaf biomass and leaf-to-stem ratio, followed by Adukara, suggesting that stover produced by such varieties would contribute to higher-quality forage that supports livestock productivity. …”
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Arbovirus vectors of epidemiological concern in the Americas: A scoping review of entomological studies on Zika, dengue and chikungunya virus vectors. by Reilly Jones, Manisha A Kulkarni, Thomas M V Davidson, RADAM-LAC Research Team, Benoit Talbot

“…Two mosquito species, Aedes aegypti and Aedes albopictus, are among the world's most prominent arboviral vectors, and are known vectors for all three viruses in the Americas.…”
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hCTLA4-Gene-Modified Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMMSCs) Maintain POSTN Secretion to Enhance the Migration Capability of Allogeneic hBMMSCs through the Integ... by Lei Song, Fei Zhang, Rui Zhou, Jun Xiao, Lei He, Fei Dai

“…Following this, ELISA, Transwell assays, wound healing assays, and western blotting were performed. …”
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Evaluation of Freshness of Farmed Two-Year-Old Acipenser persicus during Storage in Ice by Mina Seifzadeh, Ali Raoufi

“…Chilled fish is considered a fresh product and helps to ensure the development of world trade. So, the present study aimed to investigate the freshness of two-year-old farmed A. persicus by chemical, microbial, sensory, and physical experiments, and determine its shelf life during ice storage. 20 fish samples were maintained in chilled seawater tanks for 12 days. …”
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Appetite Suppression and Antiobesity Effect of a Botanical Composition Composed of Morus alba, Yerba mate, and Magnolia officinalis by Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Tae-Woo Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia

“…Obesity and its comorbidities continue to challenge the world at an alarming rate. Although the long term solution lies on lifestyle changes in the form of dieting and exercising, drug, medical food, or dietary supplement interventions are required for those who are already obese. …”
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