Recognizing and addressing burnout among healthcare workers in rural Nepal: a proof-of-concept study using Kern’s six-step theoretical framework by Raj Kumar Dangal, Eva Studer, Tula Krishna Gupta, Kristin Nguyen, Amit Suneja, Karuna Khadka, Shailina Bata Shrestha, Bibhav Acharya

“…During the first phase, we conducted a targeted needs assessment using an online survey among nine rural primary care physicians working in Charikot Hospital. We then developed learning objectives for knowledge, attitude, and skills domains based on the World Health Organization (WHO) definition of burnout. …”
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Molecular genetics of idiopathic pulmonary fibrosis by R. N. Mustafin

“…Idiopathic pulmonary fibrosis (IPF) is a severe progressive interstitial lung disease with a prevalence of 2 to 29 per 100,000 of the world’s population. Aging is a significant risk factor for IPF, and the mechanisms of aging (telomere depletion, genomic instability, mitochondrial dysfunction, loss of proteostasis) are involved in the pathogenesis of IPF. …”
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MetaTrans-FSTSF: A Transformer-Based Meta-Learning Framework for Few-Shot Time Series Forecasting in Flood Prediction by Jiange Jiang, Chen Chen, Anna Lackinger, Huimin Li, Wan Li, Qingqi Pei, Schahram Dustdar

“…Our framework was evaluated using diverse datasets, including a real-world hydrological dataset from a small catchment area in Wuyuan, China, and other benchmark time series datasets. …”
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Family planning in Pacific Island Countries and Territories (PICTs): A scoping review. by Relmah Baritama Harrington, Nichole Harvey, Sarah Larkins, Michelle Redman-MacLaren

“…More than 60% of women who would like to avoid or delay their pregnancies are unable to do so. …”
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Fraxinellone-mediated targeting of cathepsin B leakage from lysosomes induces ferroptosis in fibroblasts to inhibit hypertrophic scar formation by Wei Xu, Hao Lv, Yaxin Xue, Xiaofeng Shi, Shaotian Fu, Xiaojun Li, Chuandong Wang, Danyang Zhao, Dong Han

“…Methods The impact of fraxinellone (FRA) on the proliferation and migration capacity of human hypertrophic scar-derived fibroblasts (HSFs) was assessed by EdU proliferation, wound healing and transwell assays. Quantitative real-time PCR (qRT‒PCR), Western blot (WB), immunofluorescence staining and collagen gel contraction assays were performed to evaluate the collagen production and activation capacity of HSFs. …”
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TRENDS IN GLOBAL TRANSFORMATIONS OF COUNTRIES IN THE CONTEXT OF THEIR DEVELOPMENT AND ENSURING NATIONAL SECURITY by Olena A. Parshyna, Marharyta Yu. Parshyna, Tetiana V. Chumak, Ljudmila I. Yarmolenko

“…World development at the current stage is accompanied by complex integration processes and global transformations. …”
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Continuing the continuous harvests of food production: from the perspective of the interrelationships among cultivated land quantity, quality, and grain yield by Peng Cheng, Yang Zhang, Ke Liu, Xuesong Kong, Shiman Wu, Huafei Yan, Ping Jiang

“…Abstract The rapid population growth around the world has become one of the main challenges for countries to ensure adequate food supply. …”
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Determinants of Exclusive Breastfeeding of Infants under Six Months among Cambodian Mothers by Sopheak Um, Ying Zhen Charissa Chan, Bunkea Tol, Heng Sopheab

“…Practicing exclusive breastfeeding (EBF) in an infant’s first six months of life is recommended by the World Health Organization because of its proven effectiveness as a method to support the infant’s short- and long-term physical and cognitive development. …”
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Goiter and Its Associated Factors among Adolescent High School Girls at Tach Armachiho District, Northwest Ethiopia: An Institution-Based Cross-Sectional Study by Belaynew Mesfin, Bisrat Misganaw, Melkamu Tamir Hunegnaw, Esmael Ali Muhammad

“…The presence of goiter was estimated using criteria set by World Health Organization. Iodine content of the salt was estimated by using spot testing kits. …”
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Unveiling the rural dichotomy: the dual impact of rurality on youth mental health by Sarah Youngson, Beatriz Cuesta-Briand, Mathew Coleman

“…Most themes included both positive and negative components, as well as ambivalence, demonstrating a double-edged sword. Conclusion: The study findings support the view that mental health in rural young people is best viewed through an ecosystem lens, acknowledging the complex and dynamic interplay between interpersonal, community and environmental factors on young people. …”
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DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer by Jianan Zhang, Qi Shen, Lu Xia, Xueqiong Zhu, Xuejie Zhu

“…Cell proliferation and apoptosis rates and invasiveness and migratory capacities were determined by CCK-8 assays, BrdU staining assays and colony formation assays, fluorescence activated cell sorting (FACS), wound healing assays, and Transwell invasion assays of cervical cancer cells after DYNLT3 modulation. …”
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Reliability of Goniometric Techniques for Measuring Hip Flexor Length Using the Modified Thomas Test by Kira Eimiller, Emma Stoddard, Briana Janes, Mason Smith, Andrew Vincek

“…It was hypothesized that controlling for pelvic tilt would enhance the reliability of these measurements…”
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Internal and external influences on role stereotype adherence and gender dynamics on engineering design teams by Anastasia M. Schauer, Jessie Liu, Christopher Saldaña, Katherine Fu

“…After being assigned the documentation role, men anticipated that their contribution to the project would be significantly lower compared to women, indicating a decrease in interest or a devaluation of their role on the team. …”
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MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation by Yi Zhang, Qin-shan Li, Hong-lin Liu, Hong-ting Tang, Han-lin Yang, Dao-qiu Wu, Yu-ying Huang, Li-cheng Li, Li-hong Liu, Meng-xing Li

“…The impact of MKRN1 on CRC cell proliferation and migration was observed using CCK8, colony formation, wound healing, and transwell assays. A combination of MKRN1 quantitative proteomics, ubiquitination modification omics analysis, and a string of in vitro and in vivo experiments revealed the potential mechanisms by which MKRN1 regulates CRC metastasis. …”
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Are Functional Performance Test Scores Better When Compared to Baseline or Contralateral Limb Scores Following LE Injury in Adolescent Athletes? by Edward Jones, Jessica Jochum, Hannah Corn, Michaela O'Brien, Melissa Parks, Jamal Armoush, Amanda Annee

“…It was hypothesized that using baseline scores for comparison would be more responsive to residual deficits following injury than using the contralateral limb…”
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Global Occupational Exposure to Blood and Body Fluids among Healthcare Workers: Systematic Review and Meta-Analysis by Dechasa Adare Mengistu, Gebisa Dirirsa, Elsai Mati, Dinku Mekbib Ayele, Kefelegn Bayu, Wegene Deriba, Fekade Ketema Alemu, Yohannes Mulugeta Demmu, Yohanis Alemeshet Asefa, Abraham Geremew

“…Based on subgroup analysis by publication year, survey year, and World Health Organization regions, the highest prevalence of blood and body fluid exposure in the last 12 months was observed among articles published between 2004 and 2008 (66.3%), conducted between 2003 and 2008 (66.6%), and conducted in the Southeast Asia Region (46.9%). …”
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Neuropsychiatric adverse events associated with Glucagon-like peptide-1 receptor agonists: a pharmacovigilance analysis of the FDA Adverse Event Reporting System database by Wenchao Lu, Shihan Wang, Huilin Tang, Tao Yuan, Wei Zuo, Yuling Liu

“…Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used due to their profound efficacy in glycemic control and weight management. Real-world observations have revealed potential neuropsychiatric adverse events (AEs) associated with GLP-1RAs. …”
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Tourism planning and development: The case of Portugal’s Norte region by Ana Paula Lopes, Filomena Soares

“…The north of Portugal has a rich cultural, historical and architectural landscape heritage, including some pearls that the United Nations Educational, Scientific and Cultural Organisation has classified over the years as World Heritage Sites. With its wideranging impact on economic growth, employment and social development, tourism can be a powerful tool with which to shape the Portuguese economy, contributing to the country’s competitiveness, richness and cohesion. …”
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RELIGIOUS FAITH: EXISTENTIAL-ANTHROPOLOGICAL MEANINGS by O. I. Predko

“…Religious faith, acting as a factor in human activity, builds his value-worldview model of the world. Faith deals with the "ultimate" problems of human existence since it is of exceptional importance in solving life-meaning issues of human existence. …”
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Safety and effectiveness of appropriately and inappropriately dosed rivaroxaban or apixaban versus warfarin in patients with atrial fibrillation: a cohort study with nested case–co... by Luis Alberto García Rodríguez, Pareen Vora, Luke Roberts, Gunnar Brobert, Samuel Fatoba, María Eugenia Sáez, Antonio González-Pérez

“…Further studies on this topic from real-world populations are needed.…”
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