VIBE: an R-package for VIsualization of Bulk RNA Expression data for therapeutic targeting and disease stratification by Indu Khatri, Saskia D. van Asten, Leandro F. Moreno, Brandon W. Higgs, Christiaan Klijn, Christiaan Klijn, Francis Blokzijl, Iris C. R. M. Kolder

“…With this tool, researchers can enhance indication selection and potentially accelerate the development of novel targeted therapies with the goal of precision, personalization, and ensuring treatments align with an individual patient’s disease state across a spectrum of disorders. …”
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Integration of Universities and Employers – Potential in Building Social Capital by S. M. Apenko, A. V. Lukash, A. I. Davydov

“…The authors show promising directions of research on the subject of the article: 1) the establishment of system-wide and industry barriers that impede the development of bridging social capital for the production of an innovative product; 2) a comprehensive analysis of bridging social capital, which reflects the quality of communication and cooperation in the context of personal responsibility and competencies of officials of both participants in the educational process.…”
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Associação entre nível de atividade física nos diferentes domínios e sintomas do envelhecimento masculino by Leandro Corrêa, Airton Rombaldi, Marcelo Silva

“…Para avaliar os sintomas do envelhecimento masculino foi utilizada a escala The Aging Male’s Symptoms Scale (AMS) e para verificar o nível de AF nos diferentes domínios foi utilizado o International Physical Activity Questionnaire (IPAQ), versão longa. Foram considerados ativos aqueles que realizaram ao menos 150 minutos por semana de AF e com sintomas do envelhecimento aqueles com escore igual ou superior a 37 pontos na escala AMS. …”
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Urban vegetation and well‐being: A cross‐sectional study in Montreal, Canada by Rita Sousa‐Silva, Yan Kestens, Zoé Poirier Stephens, Benoit Thierry, Daniel Schoenig, Daniel Fuller, Meghan Winters, Audrey Smargiassi

“…In this study, we investigate the cross‐sectional associations between residential vegetation exposure and individual well‐being in Montreal, Canada, using different vegetation and well‐being measures: The proportion of grass cover, tree cover, and average NDVI value within buffers of various radii (100–1000 m) were linked to each participant's residence (n = 1072, aged 18 years or older), while well‐being was assessed using subjective happiness, emotional well‐being, and personal well‐being scales. The associations were analysed using generalised additive regression models. …”
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“Equity” in genomic health policies: a review of policies in the international arena by Prabhathi Basnayake Ralalage, Prabhathi Basnayake Ralalage, Tala Mitchell, Claire Zammit, Gareth Baynam, Gareth Baynam, Emma Kowal, Libby Masey, Julie McGaughran, Tiffany Boughtwood, Misty Jenkins, Gregory Pratt, Angeline Ferdinand

“…IntroductionThe field of genomics is rapidly evolving and has made significant impact on the diagnosis and understanding of rare and genetic diseases, in guiding precision medicine in cancer treatment, and in providing personalized risk assessment for disease development and treatment responses. …”
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Р. DESCARTES: PRINCIPLES OF RATIONALISTIC METHOD AND MORALITY (TO THE QUESTION ON THE METHODS OF SCIENTIFIC RESEARCH IN THE FIELD OF PHILOSOPHY AND SOCIAL WORK) by Оксана ОСЕТРОВА

“…The purpose of this study is to provide a philosophical critical analysis of the key principles of the rationalist method of cognition and the maxims built on its basis, proposed by R. Descartes for personal discretion. In addition, the paper focuses on those obstacles that, by obscuring the common sense of an individual, lead to the non-obviousness of the ocular, which results in the establishment and further adherence to a false conclusion instead of the true one, which will be facilitated by the use of the psychoanalytic method of research. …”
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Deaths in children in England from SARS-CoV-2 infection during the first 2 years of the pandemic: a cohort study by Shamez N Ladhani, Peter Fleming, Tom Williams, Karen Luyt, Godwin Oligbu, David Odd, Sylvia Stoianova, Anna Thursby-Pelham

“…Overall mortality rate due to COVID-19 in CYP was 3.59 (2.88–4.42) per 1 000 000 person years, being highest in the youngest (< 5 years; 4.68 (3.16–6.68)) and oldest (16/17 years; 4.83 (2.57–8.26)) CYP. …”
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Prognostic value of multi-PLD ASL radiomics in acute ischemic stroke by Zhenyu Wang, Yuan Shen, Xianxian Zhang, Qingqing Li, Congsong Dong, Shu Wang, Haihua Sun, Mingzhu Chen, Xiaolu Xu, Pinglei Pan, Pinglei Pan, Zhenyu Dai, Fei Chen, Fei Chen

“…IntroductionEarly prognosis prediction of acute ischemic stroke (AIS) can support clinicians in choosing personalized treatment plans. The aim of this study is to develop a machine learning (ML) model that uses multiple post-labeling delay times (multi-PLD) arterial spin labeling (ASL) radiomics features to achieve early and precise prediction of AIS prognosis.MethodsThis study enrolled 102 AIS patients admitted between December 2020 and September 2024. …”
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Cost Consciousness Among Dermatologists by AlFada MA

“…The survey is split into four sections, focusing on participants’ (1) demographic and workplace information; (2) knowledge of cost-related terms; (3) personal cost-consciousness level; and (4) perceived barriers to factoring cost into clinical decisions.Results: Overall, 132 practicing dermatologists participated in the survey. …”
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Neumotórax espontáneo by Lazaro Lorda Galiano, María Lourdes Hernández Echevarría, Abraham Ismael Beato Canfux, Mario Jarquín Caceres, Manuel Ceballos Hernández, Yisel del Carmen Hernández Vázquez

“…El antecedente patológico personal que más se asocia es la enfermedad pulmonar obstructiva crónica. …”
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VALENȚELE EVALUĂRII PSIHOLOGICE ALE CURRICULUMULUI by USM ADMIN

“…În ceea ce privește potențialul, studiul arată că un curriculum centrat pe abilități esențiale, cum ar fi gândirea critică, creativitatea și adaptabilitatea, are un impact pozitiv pe termen lung asupra succesului personal și profesional al elevilor. Curriculumul axat pe aceste abilități îi sprijină pe elevi nu doar în performanța academică, ci și în dezvoltarea unor competențe sociale și emoționale esențiale. …”
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"Quiero seguir en activo": Estrategias de mujeres que padecen fibromialgia para realizar actividades cotidianas básicas, instrumentales y avanzadas by Daniel Sanjuan-Sánchez, Carolina Climent-Sanz, María del Mar Patiño-Vera, Montserrat Gea-Sánchez, Francesc Rubí-Carnacea, Erica Briones Vozmediano

“…Se realizó un análisis temático siguiendo la clasificación de las actividades de la vida diaria en básicas (movimiento y desplazamiento, higiene personal y vestirse), instrumentales (limpieza, tareas domésticas y compras) y avanzadas (trabajo).  …”
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Workload-capacity imbalances and their impact on self-management complexity in patients with multimorbidity: a multicenter cross-sectional study by Binyu Zhao, Yujia Fu, Jingjie Wu, Erxu Xue, Chuyang Lai, Dandan Chen, Qiwei Wu, Jianing Yu, Qiaoyu Wu, Zhihong Ye, Jing Shao

“…In the network analysis, socioeconomic factors exhibited the central nodes (p < 0.05).Conclusions Personalized interventions designed to increase capacity and reduce workload are essential for improving self-management in multimorbid patients. …”
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Molecular Epidemiology of SARS-CoV-2 within Accra Metropolis Postlockdown by Frank T. Aboagye, Lawrence Annison, Henry Kwadwo Hackman, Maame E. Acquah, Yvonne Ashong, Isaac Owusu-Frimpong, Bill C. Egyam, Sharon Annison, George Osei-Adjei, Samuel Antwi-Baffour

“…The Alpha variant of SARS-CoV-2 is the predominant circulating variant, and persons presenting with symptoms are most likely to be diagnosed with COVID-19. …”
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Everything feels just a little heavier, more wrought with implications, you know? – a mixed-methods study examining lifestyle behaviors, health, and well-being of pregnant and post... by Sara Dube, Muhammad Asim, Jennifer Gonzalez, Gracia Dala, Michelle L. Wright, Megan J. Gray, Linda G. Kahn, Deborah Jacobvitz, Elizabeth M. Widen

“…Our work provides lessons for health care practitioners about support need for pregnant and postpartum persons amid societal disruption.…”
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Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response by Fabiola Stolfi, Claudio Brasso, Davide Raineri, Virginia Landra, Camilla Barbero Mazzucca, Ali Ghazanfar, Lorenza Scotti, Riccardo Sinella, Vincenzo Villari, Giuseppe Cappellano, Paola Rocca, Annalisa Chiocchetti

“…These results confirm the involvement of the immune system in MDD and demonstrate the existence of immunological signatures associated with the severity of major depressive episodes and treatment response that could guide clinical monitoring and future personalized therapies.…”
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“I’m living in a ‘no’ world now…”- A qualitative study of the widespread impact of living with chronic breathlessness, and experiences of identification and assessment of this symp... by Helene L. Elliott-Button, Miriam J. Johnson, Ann Hutchinson, David C. Currow, Joseph Clark

“…Clinicians were recruited from the Centre and affiliated GP practices. Recorded in-person interviews were transcribed and subjected to reflexive thematic analysis using Total Dyspnoea and Breathing Space conceptual frameworks. 20 patients (9 females), carers (4 spouses, 1 daughter), and clinicians (5 GPs, 3 advanced clinical practitioners, 2 nurses) were interviewed. …”
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Bipolar affective disorder in India: A multi-site population-based cross-sectional study by Bhavika Vajawat, Satish Suhas, Sydney Moirangthem, Channaveerachari Naveen Kumar, Mathew Varghese, Gopalkrishna Gururaj, Vivek Benegal, Girish N. Rao, NMHS National Collaborators Group

“…Substantial cross-sectional co-morbidities were noted as per MINI 6.0.0 with the diagnosis of current BPAD such as tobacco use disorder (33.3%), other substance use disorders (14.6%), and anxiety disorders (10.4%). Two-thirds of persons with current BPAD reported disability of varying severity at work (63%), social (59.3%), and family life (63%). …”
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The use of animation tools in the media space of the “Library Night” for the development of master’s students’ teamwork skills by Ekaterina A. Mamaeva, Dmitry N. Gribkov, Vladimir V. Matveev, Tatyana V. Masharova

“…With its help, the levels of their development, interconnected with personality qualities, are determined. For statistical processing, Pearson's chi-square test and Fisher's method (angular transformation) were used. …”
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Effectiveness and cost-effectiveness of a web-based routine assessment with integrated recommendations for action for depression and anxiety (RehaCAT+): protocol for a cluster rand... by Reinhold Kilian, Harald Baumeister, Yannik Terhorst, Johannes Knauer, Paula Philippi, Selina Kallinger, Sandro Eiler, Tamara Waldmann, Morten Moshagen, Martina Bader

“…Secondary outcomes are depression at discharge (T1) and 6 months follow-up (T2) as well as anxiety, satisfaction with participation in social roles and activities, pain impairment, fatigue, sleep, health-related quality of life, self-efficacy, physical functioning, alcohol, personality and health economic-specific general quality of life and socioeconomic cost and benefits at T1-3. …”
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