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    Evaluation of the performance of nucleic acid amplification tests (NAATs) in detection of chlamydia and gonorrhoea infection in vaginal specimens relative to patient infection stat... by Minttu M Rönn, Louise Mc Grath-Lone, Bethan Davies, Janet D Wilson, Helen Ward

    Published 2019-01-01
    “…Objective We evaluated the performance of nucleic acid amplification tests (NAATs) using vaginal specimens in comparison to specimens from the cervix or urine in their ability to detect chlamydia and gonorrhoea infection in women based on patient infection status (PIS).Design Systematic review.Data sources EMBASE and Ovid MEDLINE databases were searched through 3 October 2017.Eligibility criteria for selecting studies We included studies that tested samples from the vagina and ≥1 other site (cervix and/or urine) with ≥2 NAATs for chlamydia and ≥2 NAATs or 1 NAAT and culture for gonorrhoea for each site.Data extraction and synthesis Performance is defined as the sensitivity of a NAAT using a specimen site and PIS of the patient. …”
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