Associations of Maternal Complaints to Levator Ani Muscle Trauma within 9 Months after Vaginal Birth: A Prospective Observational Cohort Study by N. Kimmich, J. Birri, A. Richter, R. Zimmermann, M. Kreft

“…Between 3/2017 and 4/2019, we prospectively evaluated vaginal births of 212 primiparous women with singletons in vertex presentation≥36+0 gestational weeks for levator ani muscle (LAM) trauma by translabial ultrasound, for pelvic organ prolapse by clinical examination, and for urogynecological complaints using questionnaires 1-4 days (P1), 6-10 weeks (P2), and 6-9 months (P3) after birth. …”
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Research Progress on the Brain Effect Mechanism of Tai Chi Chuan Training by WANG Yajun, XU Shurui, LIU Jiao

“…Tai Chi Chuan training contributes to the improvement of attention, and the control of attention during training may be related to the regulation of α wave rhythm and activity of cerebral cortex. After Tai Chi Chuan training, the latency of P300 and N400 is shortened, and the ability of resource allocation, information processing and word processing is improved, so as to improve the capacity and resources of brain perception information. …”
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Loss of LRRK2 activity induces cytoskeleton defects and oxidative stress during porcine oocyte maturation by Yu-Xia Wei, Ya-Han Wang, Xiao-Ting Yu, Lin-Lin Hu, Xiao-Qiong Luo, Shao-Chen Sun

“…Further analysis indicated that LRRK2 was related with cytoskeleton dynamics since its inhibition caused spindle organization defect and chromosome misalignment, and both cytoplasmic and cortex actin decreased. Moreover, LRRK2 co-localized with mitochondria and its activity was essential for mitochondria distribution. …”
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Decoding the synergistic potential of herbal medicine and dietary supplements for treating postmenopausal osteoporosis by Jinfang Dou, Xuehong Hu, Junchang Liu, Jiaxian Liu, Chuyue Zhang, Yuelin Zhang, Xianjie Zhen, Siyu Tao, Jinghua Zhang, Guangjian Jiang

“…The 12-week experiment involved measurements of bone density and microstructure, histological evaluation of femoral trabeculae and bone cortex, quantification of osteoclasts in the femur, assessment of osteoclast differentiation factor expression (NFATc1 and C-Fos), and measurement of collagen I carboxyl-terminal peptide (CTX-1). …”
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Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…Background/Objectives: <i>Amyotrophic lateral sclerosis</i> (ALS), or Lou Gehrig’s disease, is a debilitating, incurable neurodegenerative disorder characterised by motor neuron death in the spinal cord, brainstem, and motor cortex. With an incidence rate of about 4.42 cases per 100,000 people annually, ALS severely impacts motor function and quality of life, causing progressive muscle atrophy, spasticity, paralysis, and eventually death. …”
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The Neurodevelopmental Dynamics of Multilingual Experience During Childhood: A Longitudinal Behavioral, Structural, and Functional MRI Study by Pasquale Anthony Della Rosa, Gerda Videsott, Virginia Maria Borsa, Eleonora Catricalà, Nicolò Pecco, Federica Alemanno, Matteo Canini, Andrea Falini, Rita Franceschini, Jubin Abutalebi

“…In this study, we investigated whether multilingual competence yields early changes in executive attention control mechanisms and their underlying neural structures in the frontal–striatal system, such as the dorsal anterior cingulate cortex/pre-supplemental area and the left caudate. …”
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Ultra high density imaging arrays in diffuse optical tomography for human brain mapping improve image quality and decoding performance by Zachary E. Markow, Jason W. Trobaugh, Edward J. Richter, Kalyan Tripathy, Sean M. Rafferty, Alexandra M. Svoboda, Mariel L. Schroeder, Tracy M. Burns-Yocum, Karla M. Bergonzi, Mark A. Chevillet, Emily M. Mugler, Adam T. Eggebrecht, Joseph P. Culver

“…Further, this system decoded visual stimulus position with 19–35% lower error than previous HD-DOT, throughout occipital cortex.…”
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Key regions aberrantly connected within cerebello-thalamo-cortical circuit and their genetic mechanism in schizophrenia: an fMRI meta-analysis and transcriptome study by Yarui Wei, Ziyu Wang, Kangkang Xue, Xiaoyu Niu, Longyao Ma, Shaoqiang Han, Baohong Wen, Yong Zhang, Huafu Chen, Jingliang Cheng

“…These genes were specially expressed in the brain tissue, in the neurons of the cerebellum, subcortex and cortex and during nearly all developmental stages, and constructed a protein-protein interaction network supported by 85 hub genes with functional significance. …”
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Xiao-Xu-Ming Decoction Reduced Mitophagy Activation and Improved Mitochondrial Function in Cerebral Ischemia and Reperfusion Injury by Rui Lan, Yong Zhang, Tao Wu, Yun-Zhi Ma, Bao-Qi Wang, Hai-Zhong Zheng, Ya-Na Li, Yan Wang, Chun-Qing Gu, Ji-Tao Wu

“…Ultrastructural features of mitochondria and mitophagy in the penumbra of the ischemic cortex were observed by transmission electron microscopy. …”
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Tyrosine hydroxylase of the brain and it’s regulation by glucocorticoids by E. V. Sukhareva, T. S. Kalinina, V. V. Bulygina, N. N. Dygalo

“…Moreover, our treatment led to increase in TH mRNA levels in 25- and 70-day-old animals, as well as an increase in enzyme activity in the brainstem and cerebral cortex of adult rats. The long-term changes in TH expression are limited by the perinatal period of development. …”
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The role of fMRI in the mind decoding process in adults: a systematic review by Sahal Alotaibi, Maher Mohammed Alotaibi, Faisal Saleh Alghamdi, Mishaal Abdullah Alshehri, Khaled Majed Bamusa, Ziyad Faiz Almalki, Sultan Alamri, Ahmad Joman Alghamdi, Mohammed Alhazmi, Hamid Osman, Mayeen U. Khandaker

“…Key brain regions involved include the superior temporal sulcus (STS), medial prefrontal cortex (mPFC), and temporoparietal junction (TPJ), all crucial for mentalizing (understanding others’ mental states). …”
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Neurotransmitters crosstalk and regulation in the reward circuit of subjects with behavioral addiction by Zhenlei Peng, Qiyu Jia, Junxiong Mao, Xiao Luo, Anqi Huang, Hao Zheng, Shijie Jiang, Qi Ma, Qi Ma, Chuang Ma, Qizhong Yi

“…The neurobiological underpinnings of BADs primarily involve impairments in the reward circuitry, encompassing the ventral tegmental area, nucleus accumbens in the ventral striatum, and prefrontal cortex. These brain regions form networks that communicate through neurotransmitter signaling, leading to neurobiological changes in individuals with behavioral addictions. …”
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Therapeutic Effectiveness of Mirror Therapy Combined with Music Therapy on Upper Limb Motor Function in Hemiplegic Patients with Stroke by SHI Bohan, ZHU Yan, MA Shujie, XU Qian, WANG Ping, CHEN Zhu, ZHU Weijia

“…MAS grade of the upper limb of the patients in the combined treatment group was lower than that in the conventional rehabilitation group and the mirror therapy group （<italic>P</italic>&lt;0.05）；However，there were no significant statistical differences in MAS grade between the mirror therapy group and the conventional rehabilitation group （<italic>P</italic>&gt;0.05）.ConclusionMirror therapy combined with music therapy can be more effective than mirror therapy alone for promoting the recovery of the upper limb function and the activities of daily living，also for alleviating the upper limb spasticity and improving the excitability the motor cortex of the affected brain area.…”
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Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test by Tatyana Strekalova, Nataliia Markova, Elena Shevtsova, Olga Zubareva, Anastassia Bakhmet, Harry M. Steinbusch, Sergey Bachurin, Klaus-Peter Lesch

“…Observed increases of GSK-3beta mRNA in prefrontal cortex during delayed testing session correlated with individual parameters of behavioural despair that was not found in the classic Porsolt test. …”
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Corticospinal Tract Wiring and Brain Lesion Characteristics in Unilateral Cerebral Palsy: Determinants of Upper Limb Motor and Sensory Function by Cristina Simon-Martinez, Ellen Jaspers, Lisa Mailleux, Els Ortibus, Katrijn Klingels, Nicole Wenderoth, Hilde Feys

“…Fifty-two participants with uCP (mean age (SD): 11 y and 3 m (3 y and 10 m)) underwent a single-pulse Transcranial Magnetic Stimulation session to determine CST wiring between the motor cortex and the more affected hand (n=17 contralateral, n=19 ipsilateral, and n=16 bilateral) and an MRI to determine lesion timing (n=34 periventricular (PV) lesion, n=18 corticosubcortical (CSC) lesion), location, and extent. …”
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Current conceptions and promising tools to prevent cataractogenesis by M.A. Kovalevskaya, Yu.V. Vladimirova, L.A. Filina, V.L. Kokorev

“…Many studies clearly demonstrate that Catalin (pirenoxine) eye drops provide anti-cataract effect on all layers of the lens, in particular, cortex and p osterior capsule. High therapeutic efficacy and long-term safety allow for recommending Catalin to slow the progression of cataract, in particular, early cataracts in patients under 59 years of age. …”
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Case report: Monitoring consciousness with fNIRS in a patient with prolonged reduced consciousness following hemorrhagic stroke undergoing adjunct taVNS therapy by Fei Gao, Likai Wang, Likai Wang, Zhan Wang, Yaru Tian, Jingyi Wu, Mengchun Wang, Litong Wang

“…The frontal-parietal were subdivided into 12 regions of interest (ROIs) and it was determined that the FC between the left dorsolateral prefrontal cortex (DLPFC) and the left prefrontal ROIs was 0.06 ± 0.41 before the intervention and 0.55 ± 0.24 after the intervention. …”
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tDCS cranial nerve Co-stimulation: Unveiling brainstem pathways involved in trigeminal nerve direct current stimulation in rats by Alireza Majdi, Liyi Chen, Lars E. Larsen, Robrecht Raedt, Myles Mc Laughlin

“…Differential changes in tonic and phasic LC activity highlight their roles in TN-DCS effects on the cortex. This research offers insights to improve tDCS efficacy and understanding. …”
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A Novel Mouse Model of Alzheimer's Disease with Chronic Estrogen Deficiency Leads to Glial Cell Activation and Hypertrophy by Annik Prat, Maik Behrendt, Edwige Marcinkiewicz, Sebastien Boridy, Ram M. Sairam, Nabil G. Seidah, Dusica Maysinger

“…The most prominent changes in the cerebral cortex and hippocampus of these hypoestrogenic mice were marked hypertrophy of both cortical neurons and astrocytes and an increased number of activated microglia. …”
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Renal and Hematological Effects of CLCF-1, a B-Cell-Stimulating Cytokine of the IL-6 Family by Virginia J. Savin, Mukut Sharma, Jianping Zhou, David Gennochi, Timothy Fields, Ram Sharma, Ellen T. McCarthy, Tarak Srivastava, Jos Domen, Aurélie Tormo, Jean-François Gauchat

“…CLCF-1 increased phosphorylation of STAT3 in multiple cell types, activated podocytes leading to formation of lamellipodia and decrease in basal stress fibers, increased glomerular albumin permeability, and increased STAT3 phosphorylation of peripheral blood cells and renal cortex. CLCF-1 increased urine albumin/creatinine ratio in mice and increased B-cell expression of IgG in mouse spleen. …”
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